Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10981
Gene name Gene Name - the full gene name approved by the HGNC.
RAB32, member RAS oncogene family
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RAB32
Synonyms (NCBI Gene) Gene synonyms aliases
PARK26
Disease Acronyms (UniProt) Disease acronyms from UniProt database
PARK26
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q24.3
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this g
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022613 hsa-miR-124-3p Microarray 18668037
MIRT029421 hsa-miR-26b-5p Microarray 19088304
MIRT516466 hsa-miR-6512-5p PAR-CLIP 20371350
MIRT516465 hsa-miR-8083 PAR-CLIP 20371350
MIRT516464 hsa-miR-506-5p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003924 Function GTPase activity IBA 21873635
GO:0003924 Function GTPase activity IDA 21808068
GO:0005515 Function Protein binding IPI 21808068, 22511774, 25360523, 31552791, 32296183
GO:0005525 Function GTP binding NAS 22511774
GO:0005739 Component Mitochondrion IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612906 9772 ENSG00000118508
Protein
UniProt ID Q13637
Protein name Ras-related protein Rab-32 (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:11784320, PubMed:21808068). Rabs cycle between an inactive GDP-bound form and an acti
PDB 4CYM , 4CZ2 , 5OEC , 5OED , 6FF8
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 27 194 Ras family Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung. {ECO:0000269|PubMed:11784320, ECO:0000269|PubMed:12186851}.
Sequence
Sequence length 225
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Dermatitis Dermatitis, Allergic Contact rs61816761, rs150597413, rs138726443, rs201356558, rs149484917, rs372754256, rs747301529, rs567795279, rs745915174 17374397
Unknown
Disease term Disease name Evidence References Source
Leprosy Leprosy 22019778 ClinVar, GWAS
Parkinson disease Parkinson disease 26, autosomal dominant, susceptibility to GenCC
Associations from Text Mining
Disease Name Relationship Type References
Albinism with hemorrhagic diathesis and pigmented reticuloendothelial cells Associate 36302964
Carcinogenesis Associate 18827820
Carcinoma Pancreatic Ductal Associate 32759795
Colorectal Neoplasms Associate 36539702
Diffuse Neurofibrillary Tangles with Calcification Associate 38614108
Glioblastoma Stimulate 36922509
Lewy Body Disease Associate 38614108
Mast Cell Activation Disorders Associate 35610596
Mucocutaneous Lymph Node Syndrome Associate 36042431
Multiple Sclerosis Associate 29261068