EBNA1BP2 (EBNA1 binding protein 2)

Gene Gene information from NCBI Gene database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID 10969
Gene name EBNA1 binding protein 2
Gene symbol EBNA1BP2
Synonyms (NCBI Gene)
EBP2NOBPP40
Chromosome 1
Chromosome location 1p34.2
miRNA miRNA information provided by mirtarbase database.
551
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
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miRTarBase ID miRNA Experiments Reference
MIRT006186 ebv-miR-BHRF1-1 ImmunoprecipitaionqRT-PCRWestern blot 21379335
MIRT006186 ebv-miR-BHRF1-1 ImmunoprecipitaionqRT-PCRWestern blot 21379335
MIRT006186 ebv-miR-BHRF1-1 ImmunoprecipitaionqRT-PCRWestern blot 21379335
MIRT029841 hsa-miR-26b-5p Microarray 19088304
MIRT041523 hsa-miR-193b-3p CLASH 23622248
Transcription factors Transcription factors information provided by TRRUST V2 database.
2
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
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Transcription factor Regulation Reference
MYC Activation 22169551
RB1 Activation 22169551
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
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GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0005515 Function Protein binding IPI 28514442, 32296183, 33961781, 35271311
GO:0005634 Component Nucleus IEA
GO:0005694 Component Chromosome IDA
GO:0005730 Component Nucleolus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
614443 15531 ENSG00000117395
Protein Protein information from UniProt database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q99848
Protein name Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40)
Protein function Required for the processing of the 27S pre-rRNA.
PDB 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05890 Ebp2 18 → 298 Eukaryotic rRNA processing protein EBP2 Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:11327720}.
Sequence
Sequence length 306
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Major pathway of rRNA processing in the nucleolus and cytosol
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (21)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Acute myeloid leukemia Benign rs11559312 RCV005908821
Adrenocortical carcinoma, hereditary Benign rs11559312 RCV005910303
Cervical cancer Benign rs11559312 RCV005910304
Chronic lymphocytic leukemia/small lymphocytic lymphoma Benign rs11559312 RCV005910318
Show/Hide Text Mining Associations (4)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Lymphoma Large Cell Anaplastic Associate 33040459
Muscular Diseases Associate 39438952
Neoplasms Associate 15720800, 18959818, 21220517, 33040459
Sepsis Associate 39438952