SERINC3 (serine incorporator 3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10955 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Serine incorporator 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SERINC3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1 |
Chromosome
Chromosome number
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20 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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20q13.12 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q13530 | ||||||||||
Protein name | Serine incorporator 3 (Tumor differentially expressed protein 1) | ||||||||||
Protein function | Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734). Non-ATP | ||||||||||
PDB | 7RU6 , 7RUG | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues. {ECO:0000269|PubMed:10559794}. | ||||||||||
Sequence |
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Sequence length | 473 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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