Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10933
Gene name Gene Name - the full gene name approved by the HGNC.
Mortality factor 4 like 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MORF4L1
Synonyms (NCBI Gene) Gene synonyms aliases
Eaf3, FWP006, HsT17725, MEAF3, MORFRG15, MRG15, S863-6
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q25.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019410 hsa-miR-148b-3p Microarray 17612493
MIRT020406 hsa-miR-29c-3p Sequencing 20371350
MIRT021448 hsa-miR-9-5p Microarray 17612493
MIRT021617 hsa-miR-142-3p Microarray 17612493
MIRT032039 hsa-miR-16-5p Proteomics 18668040
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000123 Component Histone acetyltransferase complex IBA 21873635
GO:0000724 Process Double-strand break repair via homologous recombination IDA 20332121
GO:0005515 Function Protein binding IPI 12963728, 14506250, 15647280, 16189514, 16230350, 20332121, 21516116, 24981860, 25416956, 31515488
GO:0005654 Component Nucleoplasm TAS
GO:0006342 Process Chromatin silencing IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607303 16989 ENSG00000185787
Protein
UniProt ID Q9UBU8
Protein name Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (MRG15) (Protein MSL3-1) (Transcription factor-like protein MRG15)
Protein function Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA intera
PDB 2AQL , 2EFI , 2F5J , 2F5K , 2LKM , 2N1D , 6AGO , 6INE , 7S4A , 8BPA , 8C60
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11717 Tudor-knot 11 53 RNA binding activity-knot of a chromodomain Family
PF05712 MRG 174 352 MRG Family
Sequence
Sequence length 362
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  ATP-dependent chromatin remodeling  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Adenocarcinoma Adenoid Cystic Carcinoma rs121913530, rs886039394, rs121913474 23685749
Coronary artery disease CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 1, Coronary Artery Disease rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 23202125, 28714975, 30104761, 29212778, 26343387, 24262325
Lung carcinoma Squamous cell carcinoma of lung, Carcinoma of lung rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355
View all (44 more)
28604730
Lung adenocarcinoma Adenocarcinoma of lung (disorder) rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370
View all (5 more)
19836008, 28604730
Unknown
Disease term Disease name Evidence References Source
Coronary heart disease Coronary heart disease 21378988, 24262325 ClinVar
Myocardial infarction Myocardial Infarction 26343387 ClinVar
Myocardial Infarction Myocardial Infarction GWAS
Coronary Heart Disease Coronary Heart Disease GWAS
Associations from Text Mining
Disease Name Relationship Type References
Atherosclerosis Associate 31460868
Carotid Stenosis Associate 31651847
Cerebral Infarction Associate 31460868
Myotonic Dystrophy Inhibit 20479119
Neoplasms Inhibit 17008723
Neurodegenerative Diseases Associate 31219803
Retinoblastoma Associate 14506250