Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10933
Gene name Gene Name - the full gene name approved by the HGNC.
Mortality factor 4 like 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MORF4L1
Synonyms (NCBI Gene) Gene synonyms aliases
Eaf3, FWP006, HsT17725, MEAF3, MORFRG15, MRG15, S863-6
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q25.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019410 hsa-miR-148b-3p Microarray 17612493
MIRT020406 hsa-miR-29c-3p Sequencing 20371350
MIRT021448 hsa-miR-9-5p Microarray 17612493
MIRT021617 hsa-miR-142-3p Microarray 17612493
MIRT032039 hsa-miR-16-5p Proteomics 18668040
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000724 Process Double-strand break repair via homologous recombination IDA 20332121
GO:0000786 Component Nucleosome IDA 27153538
GO:0000786 Component Nucleosome IEA
GO:0003682 Function Chromatin binding IEA
GO:0005515 Function Protein binding IPI 12963728, 14506250, 15647280, 16189514, 16230350, 16407074, 17577209, 20332121, 21516116, 22244764, 24981860, 25416956, 25960410, 26496610, 27107012, 28514442, 31515488, 32296183, 33961781, 36217029
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607303 16989 ENSG00000185787
Protein
UniProt ID Q9UBU8
Protein name Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (MRG15) (Protein MSL3-1) (Transcription factor-like protein MRG15)
Protein function Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA intera
PDB 2AQL , 2EFI , 2F5J , 2F5K , 2LKM , 2N1D , 6AGO , 6INE , 7S4A , 8BPA , 8C60
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11717 Tudor-knot 11 53 RNA binding activity-knot of a chromodomain Family
PF05712 MRG 174 352 MRG Family
Sequence
Sequence length 362
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  ATP-dependent chromatin remodeling  
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Coronary artery disease Coronary artery disease N/A N/A GWAS
Coronary Heart Disease Coronary heart disease N/A N/A GWAS
Lung adenocarcinoma Lung adenocarcinoma N/A N/A GWAS
Multiple Sclerosis Multiple sclerosis N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Atherosclerosis Associate 31460868
Carotid Stenosis Associate 31651847
Cerebral Infarction Associate 31460868
Myotonic Dystrophy Inhibit 20479119
Neoplasms Inhibit 17008723
Neurodegenerative Diseases Associate 31219803
Retinoblastoma Associate 14506250