Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10928
Gene name Gene Name - the full gene name approved by the HGNC.	RalA binding protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RALBP1
Synonyms (NCBI Gene) Gene synonyms aliases	RIP1, RLIP1, RLIP76
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18p11.22
Summary Summary of gene provided in NCBI Entrez Gene.	RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive

Show/Hide all(330)

miRTarBase ID	miRNA	Experiments	Reference
MIRT047750	hsa-miR-10a-5p	CLASH	23622248
MIRT047750	hsa-miR-10a-5p	CLASH	23622248
MIRT047496	hsa-miR-10b-5p	CLASH	23622248
MIRT045735	hsa-miR-125a-5p	CLASH	23622248
MIRT040266	hsa-miR-615-3p	CLASH	23622248
MIRT035794	hsa-miR-1914-5p	CLASH	23622248
MIRT1288739	hsa-miR-101	CLIP-seq
MIRT1288740	hsa-miR-106a	CLIP-seq
MIRT1288741	hsa-miR-106b	CLIP-seq
MIRT1288742	hsa-miR-1202	CLIP-seq
MIRT1288743	hsa-miR-1203	CLIP-seq
MIRT1288744	hsa-miR-1207-5p	CLIP-seq
MIRT1288745	hsa-miR-1224-3p	CLIP-seq
MIRT1288746	hsa-miR-1226	CLIP-seq
MIRT1288747	hsa-miR-1234	CLIP-seq
MIRT1288748	hsa-miR-1253	CLIP-seq
MIRT1288749	hsa-miR-1260	CLIP-seq
MIRT1288750	hsa-miR-1260b	CLIP-seq
MIRT1288751	hsa-miR-1273e	CLIP-seq
MIRT1288752	hsa-miR-1273f	CLIP-seq
MIRT1288753	hsa-miR-1280	CLIP-seq
MIRT1288754	hsa-miR-130a	CLIP-seq
MIRT1288755	hsa-miR-130b	CLIP-seq
MIRT1288756	hsa-miR-142-5p	CLIP-seq
MIRT1288757	hsa-miR-143	CLIP-seq
MIRT1288758	hsa-miR-144	CLIP-seq
MIRT1288759	hsa-miR-147	CLIP-seq
MIRT1288760	hsa-miR-148a	CLIP-seq
MIRT1288761	hsa-miR-148b	CLIP-seq
MIRT1288762	hsa-miR-152	CLIP-seq
MIRT1288763	hsa-miR-17	CLIP-seq
MIRT1288764	hsa-miR-188-3p	CLIP-seq
MIRT1288765	hsa-miR-190	CLIP-seq
MIRT1288766	hsa-miR-190b	CLIP-seq
MIRT1288767	hsa-miR-196a	CLIP-seq
MIRT1288768	hsa-miR-196b	CLIP-seq
MIRT1288769	hsa-miR-20a	CLIP-seq
MIRT1288770	hsa-miR-20b	CLIP-seq
MIRT1288771	hsa-miR-28-5p	CLIP-seq
MIRT1288772	hsa-miR-301a	CLIP-seq
MIRT1288773	hsa-miR-301b	CLIP-seq
MIRT1288774	hsa-miR-3120-3p	CLIP-seq
MIRT1288775	hsa-miR-3125	CLIP-seq
MIRT1288776	hsa-miR-3128	CLIP-seq
MIRT1288777	hsa-miR-3139	CLIP-seq
MIRT1288778	hsa-miR-3156-3p	CLIP-seq
MIRT1288779	hsa-miR-3159	CLIP-seq
MIRT1288780	hsa-miR-3177-3p	CLIP-seq
MIRT1288781	hsa-miR-3194-5p	CLIP-seq
MIRT1288782	hsa-miR-340	CLIP-seq
MIRT1288783	hsa-miR-3609	CLIP-seq
MIRT1288784	hsa-miR-3610	CLIP-seq
MIRT1288785	hsa-miR-3613-3p	CLIP-seq
MIRT1288786	hsa-miR-3666	CLIP-seq
MIRT1288787	hsa-miR-3671	CLIP-seq
MIRT1288788	hsa-miR-3682-3p	CLIP-seq
MIRT1288789	hsa-miR-3910	CLIP-seq
MIRT1288790	hsa-miR-3914	CLIP-seq
MIRT1288791	hsa-miR-3915	CLIP-seq
MIRT1288792	hsa-miR-3916	CLIP-seq
MIRT1288793	hsa-miR-3926	CLIP-seq
MIRT1288794	hsa-miR-3927	CLIP-seq
MIRT1288795	hsa-miR-3928	CLIP-seq
MIRT1288796	hsa-miR-3944-5p	CLIP-seq
MIRT1288797	hsa-miR-3972	CLIP-seq
MIRT1288798	hsa-miR-4295	CLIP-seq
MIRT1288799	hsa-miR-4420	CLIP-seq
MIRT1288800	hsa-miR-4426	CLIP-seq
MIRT1288801	hsa-miR-4436a	CLIP-seq
MIRT1288802	hsa-miR-4446-5p	CLIP-seq
MIRT1288803	hsa-miR-4451	CLIP-seq
MIRT1288804	hsa-miR-4470	CLIP-seq
MIRT1288805	hsa-miR-4476	CLIP-seq
MIRT1288806	hsa-miR-4477b	CLIP-seq
MIRT1288807	hsa-miR-451b	CLIP-seq
MIRT1288808	hsa-miR-4530	CLIP-seq
MIRT1288809	hsa-miR-454	CLIP-seq
MIRT1288810	hsa-miR-4647	CLIP-seq
MIRT1288811	hsa-miR-4652-3p	CLIP-seq
MIRT1288812	hsa-miR-4662b	CLIP-seq
MIRT1288813	hsa-miR-4700-3p	CLIP-seq
MIRT1288814	hsa-miR-4704-3p	CLIP-seq
MIRT1288815	hsa-miR-4708-5p	CLIP-seq
MIRT1288816	hsa-miR-4709-5p	CLIP-seq
MIRT1288817	hsa-miR-4711-5p	CLIP-seq
MIRT1288818	hsa-miR-4733-3p	CLIP-seq
MIRT1288819	hsa-miR-4736	CLIP-seq
MIRT1288820	hsa-miR-4763-3p	CLIP-seq
MIRT1288821	hsa-miR-4770	CLIP-seq
MIRT1288822	hsa-miR-4778-5p	CLIP-seq
MIRT1288823	hsa-miR-4786-5p	CLIP-seq
MIRT1288824	hsa-miR-4796-3p	CLIP-seq
MIRT1288825	hsa-miR-493	CLIP-seq
MIRT1288826	hsa-miR-507	CLIP-seq
MIRT1288827	hsa-miR-519d	CLIP-seq
MIRT1288828	hsa-miR-548ah	CLIP-seq
MIRT1288829	hsa-miR-548c-3p	CLIP-seq
MIRT1288830	hsa-miR-548s	CLIP-seq
MIRT1288831	hsa-miR-557	CLIP-seq
MIRT1288832	hsa-miR-558	CLIP-seq
MIRT1288833	hsa-miR-581	CLIP-seq
MIRT1288834	hsa-miR-582-5p	CLIP-seq
MIRT1288835	hsa-miR-622	CLIP-seq
MIRT1288836	hsa-miR-646	CLIP-seq
MIRT1288837	hsa-miR-665	CLIP-seq
MIRT1288838	hsa-miR-708	CLIP-seq
MIRT1288839	hsa-miR-767-3p	CLIP-seq
MIRT1288840	hsa-miR-769-5p	CLIP-seq
MIRT1288841	hsa-miR-873	CLIP-seq
MIRT1288842	hsa-miR-877	CLIP-seq
MIRT1288843	hsa-miR-93	CLIP-seq
MIRT1288739	hsa-miR-101	CLIP-seq
MIRT1288740	hsa-miR-106a	CLIP-seq
MIRT1288741	hsa-miR-106b	CLIP-seq
MIRT1288746	hsa-miR-1226	CLIP-seq
MIRT1288747	hsa-miR-1234	CLIP-seq
MIRT2085605	hsa-miR-124	CLIP-seq
MIRT2085606	hsa-miR-1252	CLIP-seq
MIRT1288748	hsa-miR-1253	CLIP-seq
MIRT2085607	hsa-miR-1299	CLIP-seq
MIRT1288756	hsa-miR-142-5p	CLIP-seq
MIRT1288758	hsa-miR-144	CLIP-seq
MIRT1288763	hsa-miR-17	CLIP-seq
MIRT1288769	hsa-miR-20a	CLIP-seq
MIRT1288770	hsa-miR-20b	CLIP-seq
MIRT2085608	hsa-miR-299-5p	CLIP-seq
MIRT2085609	hsa-miR-3117-5p	CLIP-seq
MIRT1288774	hsa-miR-3120-3p	CLIP-seq
MIRT1288775	hsa-miR-3125	CLIP-seq
MIRT2085610	hsa-miR-3126-3p	CLIP-seq
MIRT2085611	hsa-miR-3148	CLIP-seq
MIRT2085612	hsa-miR-3190	CLIP-seq
MIRT2085613	hsa-miR-3202	CLIP-seq
MIRT1288782	hsa-miR-340	CLIP-seq
MIRT1288783	hsa-miR-3609	CLIP-seq
MIRT2085614	hsa-miR-3911	CLIP-seq
MIRT1288792	hsa-miR-3916	CLIP-seq
MIRT2085615	hsa-miR-3925-3p	CLIP-seq
MIRT2085616	hsa-miR-4251	CLIP-seq
MIRT2085617	hsa-miR-4293	CLIP-seq
MIRT2085618	hsa-miR-4329	CLIP-seq
MIRT1288800	hsa-miR-4426	CLIP-seq
MIRT1288801	hsa-miR-4436a	CLIP-seq
MIRT2085619	hsa-miR-4504	CLIP-seq
MIRT1288807	hsa-miR-451b	CLIP-seq
MIRT2085620	hsa-miR-4523	CLIP-seq
MIRT2085621	hsa-miR-4533	CLIP-seq
MIRT1288810	hsa-miR-4647	CLIP-seq
MIRT1288812	hsa-miR-4662b	CLIP-seq
MIRT2085622	hsa-miR-4687-3p	CLIP-seq
MIRT1288813	hsa-miR-4700-3p	CLIP-seq
MIRT1288814	hsa-miR-4704-3p	CLIP-seq
MIRT2085623	hsa-miR-4728-3p	CLIP-seq
MIRT2085624	hsa-miR-4729	CLIP-seq
MIRT1288818	hsa-miR-4733-3p	CLIP-seq
MIRT2085625	hsa-miR-4768-5p	CLIP-seq
MIRT2085626	hsa-miR-4786-3p	CLIP-seq
MIRT1288823	hsa-miR-4786-5p	CLIP-seq
MIRT1288824	hsa-miR-4796-3p	CLIP-seq
MIRT2085627	hsa-miR-495	CLIP-seq
MIRT2085628	hsa-miR-506	CLIP-seq
MIRT1288827	hsa-miR-519d	CLIP-seq
MIRT2085629	hsa-miR-542-3p	CLIP-seq
MIRT1288828	hsa-miR-548ah	CLIP-seq
MIRT1288834	hsa-miR-582-5p	CLIP-seq
MIRT2085630	hsa-miR-766	CLIP-seq
MIRT1288840	hsa-miR-769-5p	CLIP-seq
MIRT2085631	hsa-miR-875-3p	CLIP-seq
MIRT1288843	hsa-miR-93	CLIP-seq
MIRT2085632	hsa-miR-942	CLIP-seq
MIRT1288742	hsa-miR-1202	CLIP-seq
MIRT1288746	hsa-miR-1226	CLIP-seq
MIRT2085606	hsa-miR-1252	CLIP-seq
MIRT1288752	hsa-miR-1273f	CLIP-seq
MIRT2310884	hsa-miR-1289	CLIP-seq
MIRT2085607	hsa-miR-1299	CLIP-seq
MIRT1288754	hsa-miR-130a	CLIP-seq
MIRT1288755	hsa-miR-130b	CLIP-seq
MIRT2310885	hsa-miR-135a	CLIP-seq
MIRT2310886	hsa-miR-135b	CLIP-seq
MIRT1288756	hsa-miR-142-5p	CLIP-seq
MIRT1288757	hsa-miR-143	CLIP-seq
MIRT1288760	hsa-miR-148a	CLIP-seq
MIRT1288761	hsa-miR-148b	CLIP-seq
MIRT1288762	hsa-miR-152	CLIP-seq
MIRT2310887	hsa-miR-1827	CLIP-seq
MIRT1288765	hsa-miR-190	CLIP-seq
MIRT1288766	hsa-miR-190b	CLIP-seq
MIRT1288767	hsa-miR-196a	CLIP-seq
MIRT1288768	hsa-miR-196b	CLIP-seq
MIRT1288772	hsa-miR-301a	CLIP-seq
MIRT1288773	hsa-miR-301b	CLIP-seq
MIRT2085609	hsa-miR-3117-5p	CLIP-seq
MIRT1288774	hsa-miR-3120-3p	CLIP-seq
MIRT1288775	hsa-miR-3125	CLIP-seq
MIRT2085610	hsa-miR-3126-3p	CLIP-seq
MIRT2085611	hsa-miR-3148	CLIP-seq
MIRT2310888	hsa-miR-3155	CLIP-seq
MIRT2310889	hsa-miR-3155b	CLIP-seq
MIRT1288781	hsa-miR-3194-5p	CLIP-seq
MIRT2310890	hsa-miR-3200-5p	CLIP-seq
MIRT1288782	hsa-miR-340	CLIP-seq
MIRT2310891	hsa-miR-3658	CLIP-seq
MIRT2310892	hsa-miR-3660	CLIP-seq
MIRT1288786	hsa-miR-3666	CLIP-seq
MIRT1288788	hsa-miR-3682-3p	CLIP-seq
MIRT2310893	hsa-miR-3689a-3p	CLIP-seq
MIRT2310894	hsa-miR-3689c	CLIP-seq
MIRT1288789	hsa-miR-3910	CLIP-seq
MIRT1288790	hsa-miR-3914	CLIP-seq
MIRT1288792	hsa-miR-3916	CLIP-seq
MIRT2310895	hsa-miR-3919	CLIP-seq
MIRT2085615	hsa-miR-3925-3p	CLIP-seq
MIRT2310896	hsa-miR-3925-5p	CLIP-seq
MIRT1288794	hsa-miR-3927	CLIP-seq
MIRT1288797	hsa-miR-3972	CLIP-seq
MIRT2310897	hsa-miR-4256	CLIP-seq
MIRT2085617	hsa-miR-4293	CLIP-seq
MIRT1288798	hsa-miR-4295	CLIP-seq
MIRT2310898	hsa-miR-4316	CLIP-seq
MIRT1288799	hsa-miR-4420	CLIP-seq
MIRT1288801	hsa-miR-4436a	CLIP-seq
MIRT1288803	hsa-miR-4451	CLIP-seq
MIRT2310899	hsa-miR-4469	CLIP-seq
MIRT2085619	hsa-miR-4504	CLIP-seq
MIRT2310900	hsa-miR-4514	CLIP-seq
MIRT1288807	hsa-miR-451b	CLIP-seq
MIRT2310901	hsa-miR-4526	CLIP-seq
MIRT1288808	hsa-miR-4530	CLIP-seq
MIRT1288809	hsa-miR-454	CLIP-seq
MIRT2310902	hsa-miR-4660	CLIP-seq
MIRT2085622	hsa-miR-4687-3p	CLIP-seq
MIRT2310903	hsa-miR-4692	CLIP-seq
MIRT1288813	hsa-miR-4700-3p	CLIP-seq
MIRT1288814	hsa-miR-4704-3p	CLIP-seq
MIRT1288815	hsa-miR-4708-5p	CLIP-seq
MIRT1288816	hsa-miR-4709-5p	CLIP-seq
MIRT2085624	hsa-miR-4729	CLIP-seq
MIRT1288818	hsa-miR-4733-3p	CLIP-seq
MIRT2310904	hsa-miR-4756-3p	CLIP-seq
MIRT2085625	hsa-miR-4768-5p	CLIP-seq
MIRT1288821	hsa-miR-4770	CLIP-seq
MIRT2085626	hsa-miR-4786-3p	CLIP-seq
MIRT1288823	hsa-miR-4786-5p	CLIP-seq
MIRT2310905	hsa-miR-484	CLIP-seq
MIRT1288826	hsa-miR-507	CLIP-seq
MIRT2085629	hsa-miR-542-3p	CLIP-seq
MIRT1288831	hsa-miR-557	CLIP-seq
MIRT2310906	hsa-miR-607	CLIP-seq
MIRT2310907	hsa-miR-642a	CLIP-seq
MIRT1288836	hsa-miR-646	CLIP-seq
MIRT2085630	hsa-miR-766	CLIP-seq
MIRT1288840	hsa-miR-769-5p	CLIP-seq
MIRT2085631	hsa-miR-875-3p	CLIP-seq
MIRT1288842	hsa-miR-877	CLIP-seq
MIRT2085632	hsa-miR-942	CLIP-seq
MIRT1288746	hsa-miR-1226	CLIP-seq
MIRT2393434	hsa-miR-1233	CLIP-seq
MIRT2085605	hsa-miR-124	CLIP-seq
MIRT2085606	hsa-miR-1252	CLIP-seq
MIRT2085607	hsa-miR-1299	CLIP-seq
MIRT2085609	hsa-miR-3117-5p	CLIP-seq
MIRT1288775	hsa-miR-3125	CLIP-seq
MIRT2085610	hsa-miR-3126-3p	CLIP-seq
MIRT2085611	hsa-miR-3148	CLIP-seq
MIRT2393435	hsa-miR-3173-3p	CLIP-seq
MIRT2085612	hsa-miR-3190	CLIP-seq
MIRT2085613	hsa-miR-3202	CLIP-seq
MIRT1288785	hsa-miR-3613-3p	CLIP-seq
MIRT2310892	hsa-miR-3660	CLIP-seq
MIRT2393436	hsa-miR-3689d	CLIP-seq
MIRT2085614	hsa-miR-3911	CLIP-seq
MIRT1288790	hsa-miR-3914	CLIP-seq
MIRT1288792	hsa-miR-3916	CLIP-seq
MIRT2085615	hsa-miR-3925-3p	CLIP-seq
MIRT2393437	hsa-miR-3941	CLIP-seq
MIRT2085617	hsa-miR-4293	CLIP-seq
MIRT2085619	hsa-miR-4504	CLIP-seq
MIRT1288807	hsa-miR-451b	CLIP-seq
MIRT2310901	hsa-miR-4526	CLIP-seq
MIRT2085621	hsa-miR-4533	CLIP-seq
MIRT2393438	hsa-miR-466	CLIP-seq
MIRT2393439	hsa-miR-4672	CLIP-seq
MIRT1288814	hsa-miR-4704-3p	CLIP-seq
MIRT2393440	hsa-miR-4731-3p	CLIP-seq
MIRT1288818	hsa-miR-4733-3p	CLIP-seq
MIRT2310904	hsa-miR-4756-3p	CLIP-seq
MIRT2085625	hsa-miR-4768-5p	CLIP-seq
MIRT2393441	hsa-miR-4801	CLIP-seq
MIRT2085628	hsa-miR-506	CLIP-seq
MIRT2085629	hsa-miR-542-3p	CLIP-seq
MIRT2085630	hsa-miR-766	CLIP-seq
MIRT2085631	hsa-miR-875-3p	CLIP-seq
MIRT2085632	hsa-miR-942	CLIP-seq
MIRT2607399	hsa-miR-103a	CLIP-seq
MIRT2607400	hsa-miR-107	CLIP-seq
MIRT2607401	hsa-miR-1184	CLIP-seq
MIRT1288746	hsa-miR-1226	CLIP-seq
MIRT2393434	hsa-miR-1233	CLIP-seq
MIRT2607402	hsa-miR-3151	CLIP-seq
MIRT2607403	hsa-miR-3152-5p	CLIP-seq
MIRT2607404	hsa-miR-3170	CLIP-seq
MIRT2085615	hsa-miR-3925-3p	CLIP-seq
MIRT2607405	hsa-miR-4423-5p	CLIP-seq
MIRT2607406	hsa-miR-4447	CLIP-seq
MIRT2607407	hsa-miR-4472	CLIP-seq
MIRT2607408	hsa-miR-4655-3p	CLIP-seq
MIRT2607409	hsa-miR-4685-5p	CLIP-seq
MIRT2607410	hsa-miR-4687-5p	CLIP-seq
MIRT1288814	hsa-miR-4704-3p	CLIP-seq
MIRT2085623	hsa-miR-4728-3p	CLIP-seq
MIRT1288818	hsa-miR-4733-3p	CLIP-seq
MIRT2085625	hsa-miR-4768-5p	CLIP-seq
MIRT2607411	hsa-miR-4797-5p	CLIP-seq
MIRT2607412	hsa-miR-491-5p	CLIP-seq
MIRT2085627	hsa-miR-495	CLIP-seq
MIRT2607413	hsa-miR-759	CLIP-seq
MIRT2085630	hsa-miR-766	CLIP-seq
MIRT2085632	hsa-miR-942	CLIP-seq
MIRT2607399	hsa-miR-103a	CLIP-seq
MIRT2607400	hsa-miR-107	CLIP-seq
MIRT2607401	hsa-miR-1184	CLIP-seq
MIRT2607403	hsa-miR-3152-5p	CLIP-seq
MIRT2689310	hsa-miR-3918	CLIP-seq
MIRT2607405	hsa-miR-4423-5p	CLIP-seq
MIRT2607409	hsa-miR-4685-5p	CLIP-seq
MIRT1288817	hsa-miR-4711-5p	CLIP-seq
MIRT2607411	hsa-miR-4797-5p	CLIP-seq
MIRT2689311	hsa-miR-4800-3p	CLIP-seq
MIRT2607413	hsa-miR-759	CLIP-seq

Show/Hide all(22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IBA	21873635
GO:0005096	Function	GTPase activator activity	IDA	7673236
GO:0005515	Function	Protein binding	IPI	9422736, 16189514, 17703191, 18239685, 20709745, 21516116, 23414517, 24550280, 25241761, 25416956, 25910212, 28514442, 28580172, 28851898, 29892012, 30126976, 31515488, 31980649, 32203420, 32296183, 32814053
GO:0005829	Component	Cytosol	TAS
GO:0006897	Process	Endocytosis	IBA	21873635
GO:0006935	Process	Chemotaxis	TAS	10848592
GO:0007264	Process	Small GTPase mediated signal transduction	IBA	21873635
GO:0007264	Process	Small GTPase mediated signal transduction	IPI	7673236
GO:0016020	Component	Membrane	IBA	21873635
GO:0016020	Component	Membrane	IDA	10924126, 11437348
GO:0022857	Function	Transmembrane transporter activity	IDA	10924126, 11437348
GO:0031267	Function	Small GTPase binding	IPI	7673236, 9753634, 24056301
GO:0042626	Function	ATPase-coupled transmembrane transporter activity	IDA	10924126
GO:0042626	Function	ATPase-coupled transmembrane transporter activity	TAS	11437348
GO:0042910	Function	Xenobiotic transmembrane transporter activity	IDA	10924126
GO:0043087	Process	Regulation of GTPase activity	IDA	7673236
GO:0043547	Process	Positive regulation of GTPase activity	IBA	21873635
GO:0043547	Process	Positive regulation of GTPase activity	IDA	7673236
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0055085	Process	Transmembrane transport	IDA	10924126, 11437348
GO:1900753	Process	Doxorubicin transport	IDA	10924126
GO:1990961	Process	Xenobiotic detoxification by transmembrane export across the plasma membrane	IDA	10924126

MIM	HGNC	e!Ensembl
605801	9841	ENSG00000017797

Protein

UniProt ID

Q15311

Protein name

RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (EC 7.6.2.2, EC 7.6.2.3) (Ral-interacting protein 1)

Protein function

Multifunctional protein that functions as a downstream effector of RALA and RALB (PubMed:7673236). As a GTPase-activating protein/GAP can inactivate CDC42 and RAC1 by stimulating their GTPase activity (PubMed:7673236). As part of the Ral signali

PDB

2KWH , 2KWI , 2MBG , 6ZQT , 6ZRN

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00620	RhoGAP	210 → 355	RhoGAP domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. {ECO:0000269|PubMed:11437348}.

Sequence

MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDV
VSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKK
KEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQ
IDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKV
DELKAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKV
QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVF
FTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGI
KDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVIN
ILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSS
ESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAK
AEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSI

Sequence length

655

Interactions

View interactions

	KEGG		Reactome
	Ras signaling pathway Pathways in cancer Pancreatic cancer		Rho GTPase cycle

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Hypertension	Hypertensive disease	rs13306026	23821548
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	17013881

Show/Hide Text Mining Associations (24)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Associate	26160836
Alzheimer Disease	Associate	37926360
Breast Neoplasms	Associate	26125275
Carcinoma Hepatocellular	Associate	15526362
Colorectal Neoplasms	Associate	22549157, 28682430
Diabetes Mellitus	Associate	23419874
Drug Resistant Epilepsy	Associate	17437410
Glioblastoma	Associate	31746408
Glioma	Associate	27473470
Hypobetalipoproteinemia Familial 2	Associate	23419874
Hypoglycemia	Associate	23419874
Leukemia	Associate	24839008
Lymphatic Metastasis	Associate	26125275
Melanoma	Associate	28537681
Meningioma	Associate	25993541
Mitochondrial Diseases	Associate	37926360
Neoplasm Metastasis	Associate	17706599, 22549157, 23419874, 25690670
Neoplasms	Associate	15526362, 17706599, 23419874, 24839008, 25993541, 27572296, 28537681, 28742204, 28851898
Neoplasms	Stimulate	17954908, 22549157
Neurodegenerative Diseases	Associate	37926360
Ovarian Neoplasms	Associate	17954908
Squamous Cell Carcinoma of Head and Neck	Associate	20957082
Stomach Neoplasms	Associate	27572296
Urinary Bladder Neoplasms	Stimulate	17706599

RALBP1 (ralA binding protein 1)