SUGT1 (SGT1 assembly cochaperone of MIS12 kinetochore complex)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10910 |
| Gene name | SGT1 assembly cochaperone of MIS12 kinetochore complex |
| Gene symbol | SUGT1 |
| Synonyms (NCBI Gene) |
SGT1
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| Chromosome | 13 |
| Chromosome location | 13q14.3 |
| Summary | This gene encodes a highly conserved nuclear protein involved in kinetochore function and required for the G1/S and G2/M transitions. This protein interacts with heat shock protein 90. Alternative splicing results in multiple transcript variants. Pseudoge |
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miRNA
miRNA information provided by mirtarbase database.
604
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y2Z0 | |||||||||||||||
| Protein name | Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog) | |||||||||||||||
| Protein function | May play a role in ubiquitination and subsequent proteasomal degradation of target proteins. | |||||||||||||||
| PDB | 1RL1 | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 365 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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