Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10867
Gene name Gene Name - the full gene name approved by the HGNC.
Tetraspanin 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TSPAN9
Synonyms (NCBI Gene) Gene synonyms aliases
NET-5, NET5, PP1057
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.33-p13.32
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT044686 hsa-miR-320a CLASH 23622248
MIRT035946 hsa-miR-1180-3p CLASH 23622248
MIRT1459930 hsa-miR-106a CLIP-seq
MIRT1459931 hsa-miR-106b CLIP-seq
MIRT1459932 hsa-miR-1287 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0005886 Component Plasma membrane IDA 18795891
GO:0005887 Component Integral component of plasma membrane IBA 21873635
GO:0005925 Component Focal adhesion HDA 21423176
GO:0008150 Process Biological_process ND
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
613137 21640 ENSG00000011105
Protein
UniProt ID O75954
Protein name Tetraspanin-9 (Tspan-9) (Tetraspan NET-5)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00335 Tetraspanin 9 229 Tetraspanin family Family
Tissue specificity TISSUE SPECIFICITY: Expressed in megakaryocytes and platelets (at protein level). {ECO:0000269|PubMed:18795891}.
Sequence
Sequence length 239
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 29212778
Unknown
Disease term Disease name Evidence References Source
Myocardial infarction Myocardial Infarction 21211798 ClinVar
Oligodendroglioma Oligodendroglioma GWAS
Astrocytoma Astrocytoma GWAS
Glioblastoma Glioblastoma CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587 GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Inhibit 35600044
Encephalitis Associate 26865714
Hypospadias Associate 32728162
Infections Associate 26865714
Insulin Resistance Associate 29986096
Neoplasms Inhibit 31242895
Neoplasms Associate 35600044
Neurocognitive Disorders Associate 35240980
Stomach Neoplasms Inhibit 31242895
Triple Negative Breast Neoplasms Associate 32019179