Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10867
Gene name Gene Name - the full gene name approved by the HGNC.	Tetraspanin 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TSPAN9
Synonyms (NCBI Gene) Gene synonyms aliases	NET-5, NET5, PP1057
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12p13.33-p13.32
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate

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miRTarBase ID	miRNA	Experiments	Reference
MIRT044686	hsa-miR-320a	CLASH	23622248
MIRT035946	hsa-miR-1180-3p	CLASH	23622248
MIRT1459930	hsa-miR-106a	CLIP-seq
MIRT1459931	hsa-miR-106b	CLIP-seq
MIRT1459932	hsa-miR-1287	CLIP-seq
MIRT1459933	hsa-miR-134	CLIP-seq
MIRT1459934	hsa-miR-17	CLIP-seq
MIRT1459935	hsa-miR-18a	CLIP-seq
MIRT1459936	hsa-miR-18b	CLIP-seq
MIRT1459937	hsa-miR-20a	CLIP-seq
MIRT1459938	hsa-miR-20b	CLIP-seq
MIRT1459939	hsa-miR-3118	CLIP-seq
MIRT1459940	hsa-miR-3135b	CLIP-seq
MIRT1459941	hsa-miR-4419a	CLIP-seq
MIRT1459942	hsa-miR-4510	CLIP-seq
MIRT1459943	hsa-miR-4641	CLIP-seq
MIRT1459944	hsa-miR-4735-3p	CLIP-seq
MIRT1459945	hsa-miR-4766-5p	CLIP-seq
MIRT1459946	hsa-miR-519a	CLIP-seq
MIRT1459947	hsa-miR-519b-3p	CLIP-seq
MIRT1459948	hsa-miR-519c-3p	CLIP-seq
MIRT1459949	hsa-miR-519d	CLIP-seq
MIRT1459950	hsa-miR-548q	CLIP-seq
MIRT1459951	hsa-miR-93	CLIP-seq
MIRT1459952	hsa-miR-10a	CLIP-seq
MIRT1459953	hsa-miR-10b	CLIP-seq
MIRT1459954	hsa-miR-1203	CLIP-seq
MIRT1459955	hsa-miR-125a-3p	CLIP-seq
MIRT1459956	hsa-miR-1271	CLIP-seq
MIRT1459957	hsa-miR-1468	CLIP-seq
MIRT1459958	hsa-miR-182	CLIP-seq
MIRT1459959	hsa-miR-218	CLIP-seq
MIRT1459960	hsa-miR-3117-5p	CLIP-seq
MIRT1459961	hsa-miR-3140-3p	CLIP-seq
MIRT1459962	hsa-miR-3163	CLIP-seq
MIRT1459963	hsa-miR-3173-3p	CLIP-seq
MIRT1459964	hsa-miR-339-5p	CLIP-seq
MIRT1459965	hsa-miR-3620	CLIP-seq
MIRT1459966	hsa-miR-3665	CLIP-seq
MIRT1459967	hsa-miR-3943	CLIP-seq
MIRT1459968	hsa-miR-4326	CLIP-seq
MIRT1459969	hsa-miR-4470	CLIP-seq
MIRT1459970	hsa-miR-4690-3p	CLIP-seq
MIRT1459971	hsa-miR-4691-5p	CLIP-seq
MIRT1459972	hsa-miR-4694-5p	CLIP-seq
MIRT1459973	hsa-miR-4736	CLIP-seq
MIRT1459974	hsa-miR-4779	CLIP-seq
MIRT1459975	hsa-miR-4800-3p	CLIP-seq
MIRT1459976	hsa-miR-486-3p	CLIP-seq
MIRT1459977	hsa-miR-514	CLIP-seq
MIRT1459978	hsa-miR-514b-3p	CLIP-seq
MIRT1459979	hsa-miR-548ac	CLIP-seq
MIRT1459980	hsa-miR-548ae	CLIP-seq
MIRT1459981	hsa-miR-548aj	CLIP-seq
MIRT1459982	hsa-miR-548am	CLIP-seq
MIRT1459983	hsa-miR-548d-3p	CLIP-seq
MIRT1459984	hsa-miR-548x	CLIP-seq
MIRT1459985	hsa-miR-548z	CLIP-seq
MIRT1459986	hsa-miR-587	CLIP-seq
MIRT1459987	hsa-miR-636	CLIP-seq
MIRT1459988	hsa-miR-642b	CLIP-seq
MIRT1459989	hsa-miR-671-5p	CLIP-seq
MIRT1459990	hsa-miR-9	CLIP-seq
MIRT1459991	hsa-miR-96	CLIP-seq
MIRT2138088	hsa-miR-103a	CLIP-seq
MIRT2138089	hsa-miR-107	CLIP-seq
MIRT2138090	hsa-miR-1184	CLIP-seq
MIRT2138091	hsa-miR-1207-5p	CLIP-seq
MIRT2138092	hsa-miR-1827	CLIP-seq
MIRT2138093	hsa-miR-1909	CLIP-seq
MIRT2138094	hsa-miR-3150a-3p	CLIP-seq
MIRT2138095	hsa-miR-3151	CLIP-seq
MIRT2138096	hsa-miR-3175	CLIP-seq
MIRT2138097	hsa-miR-346	CLIP-seq
MIRT2138098	hsa-miR-3909	CLIP-seq
MIRT2138099	hsa-miR-4288	CLIP-seq
MIRT2138100	hsa-miR-4418	CLIP-seq
MIRT2138101	hsa-miR-4436b-3p	CLIP-seq
MIRT2138102	hsa-miR-4447	CLIP-seq
MIRT2138103	hsa-miR-4472	CLIP-seq
MIRT2138104	hsa-miR-4649-3p	CLIP-seq
MIRT2138105	hsa-miR-4651	CLIP-seq
MIRT2138106	hsa-miR-4663	CLIP-seq
MIRT2138107	hsa-miR-4763-3p	CLIP-seq
MIRT2138108	hsa-miR-491-5p	CLIP-seq
MIRT2138109	hsa-miR-509-3-5p	CLIP-seq
MIRT2138110	hsa-miR-509-5p	CLIP-seq
MIRT2138111	hsa-miR-595	CLIP-seq
MIRT2138112	hsa-miR-608	CLIP-seq
MIRT2138113	hsa-miR-632	CLIP-seq
MIRT2138114	hsa-miR-765	CLIP-seq
MIRT2138115	hsa-miR-939	CLIP-seq
MIRT2138116	hsa-miR-940	CLIP-seq
MIRT2358985	hsa-miR-1	CLIP-seq
MIRT2138088	hsa-miR-103a	CLIP-seq
MIRT2138089	hsa-miR-107	CLIP-seq
MIRT2358986	hsa-miR-1178	CLIP-seq
MIRT2358987	hsa-miR-1197	CLIP-seq
MIRT2138091	hsa-miR-1207-5p	CLIP-seq
MIRT2358988	hsa-miR-1224-3p	CLIP-seq
MIRT2358989	hsa-miR-1253	CLIP-seq
MIRT2358990	hsa-miR-1267	CLIP-seq
MIRT2358991	hsa-miR-1293	CLIP-seq
MIRT2358992	hsa-miR-1294	CLIP-seq
MIRT2358993	hsa-miR-1321	CLIP-seq
MIRT2358994	hsa-miR-1324	CLIP-seq
MIRT2358995	hsa-miR-150	CLIP-seq
MIRT2358996	hsa-miR-185	CLIP-seq
MIRT2358997	hsa-miR-187	CLIP-seq
MIRT2138093	hsa-miR-1909	CLIP-seq
MIRT2358998	hsa-miR-1915	CLIP-seq
MIRT2358999	hsa-miR-1972	CLIP-seq
MIRT2359000	hsa-miR-206	CLIP-seq
MIRT2359001	hsa-miR-2276	CLIP-seq
MIRT2359002	hsa-miR-2467-5p	CLIP-seq
MIRT2359003	hsa-miR-298	CLIP-seq
MIRT2359004	hsa-miR-299-3p	CLIP-seq
MIRT2359005	hsa-miR-3119	CLIP-seq
MIRT2359006	hsa-miR-3126-3p	CLIP-seq
MIRT1459940	hsa-miR-3135b	CLIP-seq
MIRT1459961	hsa-miR-3140-3p	CLIP-seq
MIRT2359007	hsa-miR-3144-5p	CLIP-seq
MIRT2359008	hsa-miR-3145-3p	CLIP-seq
MIRT2138095	hsa-miR-3151	CLIP-seq
MIRT2359009	hsa-miR-3173-5p	CLIP-seq
MIRT2138096	hsa-miR-3175	CLIP-seq
MIRT2359010	hsa-miR-3188	CLIP-seq
MIRT2359011	hsa-miR-3191	CLIP-seq
MIRT2359012	hsa-miR-3194-3p	CLIP-seq
MIRT2359013	hsa-miR-3202	CLIP-seq
MIRT2359014	hsa-miR-342-5p	CLIP-seq
MIRT2359015	hsa-miR-3652	CLIP-seq
MIRT2359016	hsa-miR-3660	CLIP-seq
MIRT1459966	hsa-miR-3665	CLIP-seq
MIRT2359017	hsa-miR-3714	CLIP-seq
MIRT2359018	hsa-miR-383	CLIP-seq
MIRT2359019	hsa-miR-3935	CLIP-seq
MIRT2359020	hsa-miR-3944-5p	CLIP-seq
MIRT2359021	hsa-miR-3975	CLIP-seq
MIRT2359022	hsa-miR-4251	CLIP-seq
MIRT2359023	hsa-miR-4252	CLIP-seq
MIRT2359024	hsa-miR-4270	CLIP-seq
MIRT2359025	hsa-miR-4286	CLIP-seq
MIRT2359026	hsa-miR-4306	CLIP-seq
MIRT2359027	hsa-miR-432	CLIP-seq
MIRT2359028	hsa-miR-4329	CLIP-seq
MIRT1459941	hsa-miR-4419a	CLIP-seq
MIRT2359029	hsa-miR-4430	CLIP-seq
MIRT2359030	hsa-miR-4436a	CLIP-seq
MIRT2138101	hsa-miR-4436b-3p	CLIP-seq
MIRT2359031	hsa-miR-4441	CLIP-seq
MIRT2359032	hsa-miR-4443	CLIP-seq
MIRT2138102	hsa-miR-4447	CLIP-seq
MIRT2359033	hsa-miR-4455	CLIP-seq
MIRT2359034	hsa-miR-4457	CLIP-seq
MIRT1459969	hsa-miR-4470	CLIP-seq
MIRT2138103	hsa-miR-4472	CLIP-seq
MIRT2359035	hsa-miR-4483	CLIP-seq
MIRT2359036	hsa-miR-4488	CLIP-seq
MIRT2359037	hsa-miR-4492	CLIP-seq
MIRT2359038	hsa-miR-4498	CLIP-seq
MIRT1459942	hsa-miR-4510	CLIP-seq
MIRT2359039	hsa-miR-4514	CLIP-seq
MIRT2359040	hsa-miR-4522	CLIP-seq
MIRT2359041	hsa-miR-4526	CLIP-seq
MIRT2359042	hsa-miR-4533	CLIP-seq
MIRT2359043	hsa-miR-4644	CLIP-seq
MIRT2359044	hsa-miR-4645-3p	CLIP-seq
MIRT2138105	hsa-miR-4651	CLIP-seq
MIRT2359045	hsa-miR-4652-5p	CLIP-seq
MIRT2359046	hsa-miR-4664-5p	CLIP-seq
MIRT2359047	hsa-miR-4677-3p	CLIP-seq
MIRT2359048	hsa-miR-4679	CLIP-seq
MIRT2359049	hsa-miR-4688	CLIP-seq
MIRT2359050	hsa-miR-4690-5p	CLIP-seq
MIRT2359051	hsa-miR-4692	CLIP-seq
MIRT2359052	hsa-miR-4697-5p	CLIP-seq
MIRT2359053	hsa-miR-4713-5p	CLIP-seq
MIRT2359054	hsa-miR-4731-5p	CLIP-seq
MIRT1459973	hsa-miR-4736	CLIP-seq
MIRT2359055	hsa-miR-4739	CLIP-seq
MIRT2359056	hsa-miR-4755-3p	CLIP-seq
MIRT2359057	hsa-miR-4756-5p	CLIP-seq
MIRT2359058	hsa-miR-4758-3p	CLIP-seq
MIRT2359059	hsa-miR-4761-3p	CLIP-seq
MIRT2138107	hsa-miR-4763-3p	CLIP-seq
MIRT1459974	hsa-miR-4779	CLIP-seq
MIRT2359060	hsa-miR-4786-3p	CLIP-seq
MIRT2359061	hsa-miR-485-5p	CLIP-seq
MIRT1459976	hsa-miR-486-3p	CLIP-seq
MIRT2359062	hsa-miR-490-5p	CLIP-seq
MIRT2138108	hsa-miR-491-5p	CLIP-seq
MIRT2359063	hsa-miR-492	CLIP-seq
MIRT1459946	hsa-miR-519a	CLIP-seq
MIRT1459947	hsa-miR-519b-3p	CLIP-seq
MIRT1459948	hsa-miR-519c-3p	CLIP-seq
MIRT2359064	hsa-miR-520g	CLIP-seq
MIRT2359065	hsa-miR-520h	CLIP-seq
MIRT2359066	hsa-miR-532-3p	CLIP-seq
MIRT2359067	hsa-miR-541	CLIP-seq
MIRT2359068	hsa-miR-582-3p	CLIP-seq
MIRT2138112	hsa-miR-608	CLIP-seq
MIRT2359069	hsa-miR-613	CLIP-seq
MIRT2359070	hsa-miR-637	CLIP-seq
MIRT2359071	hsa-miR-645	CLIP-seq
MIRT2359072	hsa-miR-649	CLIP-seq
MIRT2359073	hsa-miR-654-3p	CLIP-seq
MIRT2359074	hsa-miR-654-5p	CLIP-seq
MIRT1459989	hsa-miR-671-5p	CLIP-seq
MIRT2359075	hsa-miR-760	CLIP-seq
MIRT2359076	hsa-miR-762	CLIP-seq
MIRT2359077	hsa-miR-767-3p	CLIP-seq
MIRT2138116	hsa-miR-940	CLIP-seq
MIRT2138090	hsa-miR-1184	CLIP-seq
MIRT2396427	hsa-miR-1205	CLIP-seq
MIRT1459957	hsa-miR-1468	CLIP-seq
MIRT2396428	hsa-miR-2467-3p	CLIP-seq
MIRT1459960	hsa-miR-3117-5p	CLIP-seq
MIRT2396429	hsa-miR-3158-5p	CLIP-seq
MIRT2396430	hsa-miR-3678-3p	CLIP-seq
MIRT2396431	hsa-miR-3919	CLIP-seq
MIRT2396432	hsa-miR-3929	CLIP-seq
MIRT2396433	hsa-miR-4324	CLIP-seq
MIRT2396434	hsa-miR-4419b	CLIP-seq
MIRT2396435	hsa-miR-4478	CLIP-seq
MIRT1459972	hsa-miR-4694-5p	CLIP-seq
MIRT1459975	hsa-miR-4800-3p	CLIP-seq
MIRT2396436	hsa-miR-627	CLIP-seq
MIRT2396437	hsa-miR-924	CLIP-seq
MIRT2358995	hsa-miR-150	CLIP-seq
MIRT2358998	hsa-miR-1915	CLIP-seq
MIRT2462502	hsa-miR-3155	CLIP-seq
MIRT2462503	hsa-miR-3155b	CLIP-seq
MIRT2462504	hsa-miR-3189-3p	CLIP-seq
MIRT2462505	hsa-miR-3686	CLIP-seq
MIRT2462506	hsa-miR-4279	CLIP-seq
MIRT2462507	hsa-miR-450b-3p	CLIP-seq
MIRT2462508	hsa-miR-4652-3p	CLIP-seq
MIRT2462509	hsa-miR-4659a-3p	CLIP-seq
MIRT2462510	hsa-miR-4659b-3p	CLIP-seq
MIRT2462511	hsa-miR-4713-3p	CLIP-seq
MIRT2359053	hsa-miR-4713-5p	CLIP-seq
MIRT2462512	hsa-miR-4726-3p	CLIP-seq
MIRT2462513	hsa-miR-4742-3p	CLIP-seq
MIRT2462514	hsa-miR-484	CLIP-seq
MIRT2359066	hsa-miR-532-3p	CLIP-seq
MIRT2462515	hsa-miR-638	CLIP-seq
MIRT2462516	hsa-miR-769-3p	CLIP-seq
MIRT2462517	hsa-miR-942	CLIP-seq
MIRT2652226	hsa-miR-1236	CLIP-seq
MIRT2652227	hsa-miR-2964a-5p	CLIP-seq
MIRT2652228	hsa-miR-3183	CLIP-seq
MIRT2652229	hsa-miR-3654	CLIP-seq
MIRT2138098	hsa-miR-3909	CLIP-seq
MIRT2652230	hsa-miR-4463	CLIP-seq
MIRT2652231	hsa-miR-4520a-3p	CLIP-seq
MIRT2652232	hsa-miR-4638-3p	CLIP-seq
MIRT2652233	hsa-miR-4723-3p	CLIP-seq
MIRT2652226	hsa-miR-1236	CLIP-seq
MIRT2652227	hsa-miR-2964a-5p	CLIP-seq
MIRT2652228	hsa-miR-3183	CLIP-seq
MIRT2652229	hsa-miR-3654	CLIP-seq
MIRT2138098	hsa-miR-3909	CLIP-seq
MIRT2652230	hsa-miR-4463	CLIP-seq
MIRT2652231	hsa-miR-4520a-3p	CLIP-seq
MIRT2652232	hsa-miR-4638-3p	CLIP-seq
MIRT2652233	hsa-miR-4723-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0001780	Process	Neutrophil homeostasis	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	18795891
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0016020	Component	Membrane	IEA
GO:0038063	Process	Collagen-activated tyrosine kinase receptor signaling pathway	IEA
GO:0051881	Process	Regulation of mitochondrial membrane potential	IEA
GO:0070527	Process	Platelet aggregation	IEA
GO:0097197	Component	Tetraspanin-enriched microdomain	IDA	18795891
GO:0098953	Process	Receptor diffusion trapping	IEA
GO:0140494	Component	Migrasome	IEA
GO:0160040	Process	Mitocytosis	IEA

MIM	HGNC	e!Ensembl
613137	21640	ENSG00000011105

Protein

UniProt ID

O75954

Protein name

Tetraspanin-9 (Tspan-9) (Tetraspan NET-5)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00335	Tetraspanin	9 → 229	Tetraspanin family	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in megakaryocytes and platelets (at protein level). {ECO:0000269|PubMed:18795891}.

Sequence

MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAI
GTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLK
EGLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDWYPVLGENTVPDRCCMENSQGCGRN
ATTPLWRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHRTGKKYDA

Sequence length

239

Interactions

View interactions

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Astrocytoma	Astrocytoma	N/A	N/A	GWAS
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS
Glioblastoma	Glioblastoma	N/A	N/A	GWAS
Myocardial Infarction	Myocardial infarction	N/A	N/A	GWAS
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Carcinoma Hepatocellular	Inhibit	35600044
Encephalitis	Associate	26865714
Hypospadias	Associate	32728162
Infections	Associate	26865714
Insulin Resistance	Associate	29986096
Neoplasms	Inhibit	31242895
Neoplasms	Associate	35600044
Neurocognitive Disorders	Associate	35240980
Stomach Neoplasms	Inhibit	31242895
Triple Negative Breast Neoplasms	Associate	32019179

TSPAN9 (tetraspanin 9)