PGRMC1 (progesterone receptor membrane component 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10857 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Progesterone receptor membrane component 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PGRMC1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Dap1, HPR6.6, IZA, MPR |
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Chromosome
Chromosome number
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X |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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Xq24 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | O00264 | ||||||||||
| Protein name | Membrane-associated progesterone receptor component 1 (mPR) (Dap1) (IZA) | ||||||||||
| Protein function | Component of a progesterone-binding protein complex (PubMed:28396637). Binds progesterone (PubMed:25675345). Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitectur | ||||||||||
| PDB | 4X8Y | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected in urine (at protein level) (PubMed:36213313, PubMed:37453717). Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472). Widely expressed, with highest expression in liver and kidney. {ECO:0000269|PubMe | ||||||||||
| Sequence |
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| Sequence length | 195 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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