Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10782
Gene name	Zinc finger protein 274
Gene symbol	ZNF274
Synonyms (NCBI Gene)	HFB101ZF2ZKSCAN19ZSCAN51
Chromosome	19
Chromosome location	19q13.43
Summary	This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes

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miRTarBase ID	miRNA	Experiments	Reference
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT647482	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT647481	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT647480	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT647479	hsa-miR-4764-3p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT626305	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT641110	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT641109	hsa-miR-5590-5p	HITS-CLIP	23824327
MIRT641108	hsa-miR-4659a-5p	HITS-CLIP	23824327
MIRT641107	hsa-miR-4659b-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT641106	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT626306	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT626305	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT626304	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT626303	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT626302	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	27418678
MIRT611226	hsa-miR-1324	HITS-CLIP	27418678
MIRT611226	hsa-miR-1324	HITS-CLIP	27418678
MIRT611226	hsa-miR-1324	HITS-CLIP	27418678
MIRT611225	hsa-miR-3176	HITS-CLIP	27418678
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	27418678
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	27418678
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	27418678
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	27418678
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	27418678
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	27418678
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	27418678
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	27418678
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	27418678
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	27418678
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	27418678
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	27418678
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	27418678
MIRT611222	hsa-miR-525-5p	HITS-CLIP	27418678
MIRT611222	hsa-miR-525-5p	HITS-CLIP	27418678
MIRT611222	hsa-miR-525-5p	HITS-CLIP	27418678
MIRT611222	hsa-miR-525-5p	HITS-CLIP	27418678
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT647482	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT647481	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT647480	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT647479	hsa-miR-4764-3p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT626305	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT641110	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT641109	hsa-miR-5590-5p	HITS-CLIP	23824327
MIRT641108	hsa-miR-4659a-5p	HITS-CLIP	23824327
MIRT641107	hsa-miR-4659b-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT641106	hsa-miR-4776-3p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT626306	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT626305	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT626304	hsa-miR-7112-3p	HITS-CLIP	23824327
MIRT626303	hsa-miR-4711-5p	HITS-CLIP	23824327
MIRT626302	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT611227	hsa-miR-4524b-3p	HITS-CLIP	23824327
MIRT611226	hsa-miR-1324	HITS-CLIP	23824327
MIRT611225	hsa-miR-3176	HITS-CLIP	23824327
MIRT611224	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611223	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT611222	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT611221	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT1520361	hsa-miR-1909	CLIP-seq
MIRT1520362	hsa-miR-4659a-3p	CLIP-seq
MIRT1520363	hsa-miR-4659b-3p	CLIP-seq
MIRT1520364	hsa-miR-548an	CLIP-seq
MIRT1520365	hsa-miR-148a	CLIP-seq
MIRT1520366	hsa-miR-148b	CLIP-seq
MIRT1520367	hsa-miR-152	CLIP-seq
MIRT1520368	hsa-miR-2054	CLIP-seq
MIRT1520369	hsa-miR-216a	CLIP-seq
MIRT1520370	hsa-miR-216b	CLIP-seq
MIRT1520371	hsa-miR-3074-3p	CLIP-seq
MIRT1520372	hsa-miR-3691-5p	CLIP-seq
MIRT1520373	hsa-miR-380	CLIP-seq
MIRT1520374	hsa-miR-4318	CLIP-seq
MIRT1520375	hsa-miR-4477a	CLIP-seq
MIRT1520376	hsa-miR-4693-5p	CLIP-seq
MIRT1520377	hsa-miR-4752	CLIP-seq
MIRT1520378	hsa-miR-4764-5p	CLIP-seq
MIRT1520379	hsa-miR-619	CLIP-seq
MIRT1520380	hsa-miR-889	CLIP-seq
MIRT1520381	hsa-miR-892a	CLIP-seq
MIRT1520375	hsa-miR-4477a	CLIP-seq
MIRT2376779	hsa-miR-181a	CLIP-seq
MIRT2376780	hsa-miR-181b	CLIP-seq
MIRT2376781	hsa-miR-181c	CLIP-seq
MIRT2376782	hsa-miR-181d	CLIP-seq
MIRT2376783	hsa-miR-1910	CLIP-seq
MIRT2376784	hsa-miR-23a	CLIP-seq
MIRT2376785	hsa-miR-23b	CLIP-seq
MIRT2376786	hsa-miR-23c	CLIP-seq
MIRT2376787	hsa-miR-4262	CLIP-seq
MIRT2376788	hsa-miR-455-3p	CLIP-seq
MIRT2464178	hsa-miR-3646	CLIP-seq
MIRT2464179	hsa-miR-4765	CLIP-seq
MIRT2464178	hsa-miR-3646	CLIP-seq
MIRT2464179	hsa-miR-4765	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
TRIM28	Unknown	21170338

Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	TAS	10777669
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0003682	Function	Chromatin binding	IDA	27029610
GO:0005515	Function	Protein binding	IPI	21170338, 27029610
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	IEA
GO:0005730	Component	Nucleolus	TAS	10777669
GO:0005737	Component	Cytoplasm	IEA
GO:0006338	Process	Chromatin remodeling	IMP	27029610
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	TAS	10520746
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0043565	Function	Sequence-specific DNA binding	IDA	21170338
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
605467	13068	ENSG00000171606

Q96GC6

Protein name

Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274) (Zinc finger protein HFB101) (Zinc finger protein with KRAB and SCAN domains 19) (Zinc finger protein zfp2) (Zf2)

Protein function

Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	13 → 54	KRAB box	Family
PF02023	SCAN	157 → 246	SCAN domain	Domain
PF01352	KRAB	286 → 327	KRAB box	Family
PF00096	zf-C2H2	535 → 557	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	563 → 585	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	591 → 613	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	619 → 641	Zinc finger, C2H2 type	Domain

Sequence

MASRLPTAWSCEPVTFEDVTLGFTPEEWGLLDLKQKSLYREVMLENYRNLVSVEHQLSKP
DVVSQLEEAEDFWPVERGIPQDTIPEYPELQLDPKLDPLPAESPLMNIEVVEVLTLNQEV
AGPRNAQIQALYAEDGSLSADAPSEQVQQQGKHPGDPEAARQRFRQFRYKDMTGPREALD
QLRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQEVVALVEGVT
WMSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQDVAVDFSREE
WGLLGPTQRTEYRDVMLETFGHLVSVGWETTLENKELAPNSDIPEEEPAPSLKVQESSRD
CALSSTLEDTLQGGVQEVQDTVLKQMESAQEKDLPQKKHFDNRESQANSGALDTNQVSLQ
KIDNPESQANSGALDTNQVLLHKIPPRKRLRKRDSQVKSMKHNSRVKIHQKSCERQKAKE
GNGCRKTFSRSTKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHTGERPYVCQDC
GKGFVQSSSLTQHQRVHSGERPFECQECGRTFNDRSAISQHLRTHTGAKPYKCQDCGKAF
RQSSHLIRHQRTHTGERPYACNKCGKAFTQSSHLIGHQRTHNRTKRKKKQPTS

Sequence length

653

Interactions

View interactions

	KEGG		Reactome
	Neurotrophin signaling pathway		Generic Transcription Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
OVARIAN CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Leukemia Myeloid Acute	Associate	30190467, 36626981	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	30190467	★★★★★ ★☆☆☆☆ Found in Text Mining only
Non alcoholic Fatty Liver Disease	Associate	23931760	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prader Willi Syndrome	Associate	24760766, 32977341	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF274 (zinc finger protein 274)