Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10745
Gene name Gene Name - the full gene name approved by the HGNC.	Putative homeodomain transcription factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PHTF1
Synonyms (NCBI Gene) Gene synonyms aliases	PHTF
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p13.2

Show/Hide all(52)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024866	hsa-miR-215-5p	Microarray	19074876
MIRT026618	hsa-miR-192-5p	Microarray	19074876
MIRT030876	hsa-miR-21-5p	Microarray	18591254
MIRT050325	hsa-miR-25-3p	CLASH	23622248
MIRT042377	hsa-miR-484	CLASH	23622248
MIRT040056	hsa-miR-615-3p	CLASH	23622248
MIRT1232449	hsa-miR-101	CLIP-seq
MIRT1232450	hsa-miR-1278	CLIP-seq
MIRT1232451	hsa-miR-128	CLIP-seq
MIRT1232452	hsa-miR-27a	CLIP-seq
MIRT1232453	hsa-miR-27b	CLIP-seq
MIRT1232454	hsa-miR-3123	CLIP-seq
MIRT1232455	hsa-miR-3646	CLIP-seq
MIRT1232456	hsa-miR-3925-5p	CLIP-seq
MIRT1232457	hsa-miR-3976	CLIP-seq
MIRT1232458	hsa-miR-4724-5p	CLIP-seq
MIRT1232459	hsa-miR-4753-3p	CLIP-seq
MIRT1232460	hsa-miR-539	CLIP-seq
MIRT1232449	hsa-miR-101	CLIP-seq
MIRT2593168	hsa-miR-1207-3p	CLIP-seq
MIRT1232450	hsa-miR-1278	CLIP-seq
MIRT1232451	hsa-miR-128	CLIP-seq
MIRT2593169	hsa-miR-140-3p	CLIP-seq
MIRT1232452	hsa-miR-27a	CLIP-seq
MIRT1232453	hsa-miR-27b	CLIP-seq
MIRT2593170	hsa-miR-3152-3p	CLIP-seq
MIRT2593171	hsa-miR-3647-3p	CLIP-seq
MIRT2593172	hsa-miR-4422	CLIP-seq
MIRT1232458	hsa-miR-4724-5p	CLIP-seq
MIRT2593173	hsa-miR-511	CLIP-seq
MIRT2593174	hsa-miR-520d-5p	CLIP-seq
MIRT2593175	hsa-miR-524-5p	CLIP-seq
MIRT2593176	hsa-miR-552	CLIP-seq
MIRT2593177	hsa-miR-599	CLIP-seq
MIRT2593178	hsa-miR-664	CLIP-seq
MIRT1232449	hsa-miR-101	CLIP-seq
MIRT2593168	hsa-miR-1207-3p	CLIP-seq
MIRT1232450	hsa-miR-1278	CLIP-seq
MIRT1232451	hsa-miR-128	CLIP-seq
MIRT2593169	hsa-miR-140-3p	CLIP-seq
MIRT1232452	hsa-miR-27a	CLIP-seq
MIRT1232453	hsa-miR-27b	CLIP-seq
MIRT2593170	hsa-miR-3152-3p	CLIP-seq
MIRT2593171	hsa-miR-3647-3p	CLIP-seq
MIRT2593172	hsa-miR-4422	CLIP-seq
MIRT1232458	hsa-miR-4724-5p	CLIP-seq
MIRT2593173	hsa-miR-511	CLIP-seq
MIRT2593174	hsa-miR-520d-5p	CLIP-seq
MIRT2593175	hsa-miR-524-5p	CLIP-seq
MIRT2593176	hsa-miR-552	CLIP-seq
MIRT2593177	hsa-miR-599	CLIP-seq
MIRT2593178	hsa-miR-664	CLIP-seq

Show/Hide all(4)

GO ID	Ontology	Definition	Evidence
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
604950	8939	ENSG00000116793

Protein

UniProt ID

Q9UMS5

Protein name

Protein PHTF1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12129	Phtf-FEM1B_bdg	5 → 151	Male germ-cell putative homeodomain transcription factor	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed with highest levels in testis. {ECO:0000269|PubMed:10729229}.

Sequence

MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGLKNKPKKMGHIKPDLIDVDLIRGST
FAKAKPEIPWTSLTRKGLVRVVFFPLFSNWWIQVTSLRIFVWLLLLYFMQVIAIVLYLMM
PIVNISEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVNGDGSRENGNN
SSDKVRGIETLESVPIIGGFWETIFGNRIKRVKLISNKGTETDNDPSCVHPIIKRRQCRP
EIRMWQTREKAKFSDGEKCRREAFRRLGNGVSDDLSSEEDGEARTQMILLRRSVEGASSD
NGCEVKNRKSILSRHLNSQVKKTTTRWCHIVRDSDSLAESEFESAAFSQGSRSGVSGGSR
SLNMSRRDSESTRHDSETEDMLWDDLLHGPECRSSVTSDSEGAHVNTLHSGTKRDPKEDV
FQQNHLFWLQNSSPSSDRVSAIIWEGNECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLG
NVVTIGLAFFPFLHRLFREKSLDQLKSISAEEILTLFCGAPPVTPIIVLSIINFFERLCL
TWMFFFMMCVAERTYKQRFLFAKLFSHITSARKARKYEIPHFRLKKVENIKIWLSLRSYL
KRRGPQRSVDVVVSSVFLLTLSIAFICCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLR
LASLGSETNKKYSNVSILLTEQINLYLKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPF
RLYGLTMNPLIYNITRVVILSAVSGVISDLLGFNIRLWKIKS

Sequence length

762

Interactions

View interactions

Show/Hide Unknown Diseases (7)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Carcinoma	Basal cell carcinoma	N/A	N/A	GWAS
Crohn Disease	Crohn's disease	N/A	N/A	GWAS
Giant Cell Arteritis	Giant cell arteritis	N/A	N/A	GWAS
Hyperthyroidism	Hyperthyroidism	N/A	N/A	GWAS
Hypothyroidism	Hypothyroidism	N/A	N/A	GWAS
Rheumatoid arthritis	Rheumatoid arthritis	N/A	N/A	GWAS
Systemic lupus erythematosus	Systemic lupus erythematosus	N/A	N/A	GWAS

Show/Hide Text Mining Associations (12)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Anemia Pernicious	Associate	34145262
Arthritis Juvenile	Associate	20722033
Arthritis Rheumatoid	Associate	27898717, 33740106
Autoimmune Diseases	Associate	22493691
Breast Neoplasms	Associate	26472073
Cardiomyopathies	Associate	33288658
Crohn Disease	Associate	20722033
Diabetes Mellitus Type 1	Associate	20089178, 34521982
Hypothyroidism	Associate	22493691
Multiple Sclerosis	Associate	20722033
Muscular Dystrophy Duchenne	Associate	33740106
Tuberculosis Meningeal	Associate	33740106

PHTF1 (putative homeodomain transcription factor 1)