Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10728
Gene name	Prostaglandin E synthase 3
Gene symbol	PTGES3
Synonyms (NCBI Gene)	P23TEBPcPGES
Chromosome	12
Chromosome location	12q13.3\|12
Summary	This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional a

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miRTarBase ID	miRNA	Experiments	Reference
MIRT037524	hsa-miR-744-5p	CLASH	23622248
MIRT510910	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT510909	hsa-miR-3668	PAR-CLIP	20371350
MIRT510908	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT510910	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT510909	hsa-miR-3668	PAR-CLIP	20371350
MIRT510908	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT510910	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT510909	hsa-miR-3668	PAR-CLIP	23446348
MIRT510908	hsa-miR-4709-5p	PAR-CLIP	23446348
MIRT439873	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT439874	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT439873	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT726836	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT726835	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT726834	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT726833	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT439874	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT510910	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT510909	hsa-miR-3668	PAR-CLIP	20371350
MIRT510908	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT510910	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT510909	hsa-miR-3668	PAR-CLIP	20371350
MIRT510908	hsa-miR-4709-5p	PAR-CLIP	20371350
MIRT510910	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT510909	hsa-miR-3668	PAR-CLIP	23446348
MIRT510908	hsa-miR-4709-5p	PAR-CLIP	23446348
MIRT1272737	hsa-miR-1206	CLIP-seq
MIRT1272738	hsa-miR-1251	CLIP-seq
MIRT1272739	hsa-miR-1252	CLIP-seq
MIRT1272740	hsa-miR-125a-3p	CLIP-seq
MIRT1272741	hsa-miR-1264	CLIP-seq
MIRT1272742	hsa-miR-1273f	CLIP-seq
MIRT1272743	hsa-miR-129-5p	CLIP-seq
MIRT1272744	hsa-miR-1296	CLIP-seq
MIRT1272745	hsa-miR-1303	CLIP-seq
MIRT1272746	hsa-miR-130a	CLIP-seq
MIRT1272747	hsa-miR-130b	CLIP-seq
MIRT1272748	hsa-miR-137	CLIP-seq
MIRT1272749	hsa-miR-141	CLIP-seq
MIRT1272750	hsa-miR-143	CLIP-seq
MIRT1272751	hsa-miR-148a	CLIP-seq
MIRT1272752	hsa-miR-148b	CLIP-seq
MIRT1272753	hsa-miR-152	CLIP-seq
MIRT1272754	hsa-miR-154	CLIP-seq
MIRT1272755	hsa-miR-186	CLIP-seq
MIRT1272756	hsa-miR-18a	CLIP-seq
MIRT1272757	hsa-miR-18b	CLIP-seq
MIRT1272758	hsa-miR-19a	CLIP-seq
MIRT1272759	hsa-miR-19b	CLIP-seq
MIRT1272760	hsa-miR-200a	CLIP-seq
MIRT1272761	hsa-miR-223	CLIP-seq
MIRT1272762	hsa-miR-2467-3p	CLIP-seq
MIRT1272763	hsa-miR-2681	CLIP-seq
MIRT1272764	hsa-miR-2909	CLIP-seq
MIRT1272765	hsa-miR-301a	CLIP-seq
MIRT1272766	hsa-miR-301b	CLIP-seq
MIRT1272767	hsa-miR-302f	CLIP-seq
MIRT1272768	hsa-miR-3124-3p	CLIP-seq
MIRT1272769	hsa-miR-3135	CLIP-seq
MIRT1272770	hsa-miR-3140-5p	CLIP-seq
MIRT1272771	hsa-miR-3157-5p	CLIP-seq
MIRT1272772	hsa-miR-3160-5p	CLIP-seq
MIRT1272773	hsa-miR-3185	CLIP-seq
MIRT1272774	hsa-miR-3189-5p	CLIP-seq
MIRT1272775	hsa-miR-3192	CLIP-seq
MIRT1272776	hsa-miR-320e	CLIP-seq
MIRT1272777	hsa-miR-323b-3p	CLIP-seq
MIRT1272778	hsa-miR-337-3p	CLIP-seq
MIRT1272779	hsa-miR-338-5p	CLIP-seq
MIRT1272780	hsa-miR-3591-3p	CLIP-seq
MIRT1272781	hsa-miR-3591-5p	CLIP-seq
MIRT1272782	hsa-miR-3611	CLIP-seq
MIRT1272783	hsa-miR-3613-3p	CLIP-seq
MIRT1272784	hsa-miR-3664-3p	CLIP-seq
MIRT1272785	hsa-miR-3666	CLIP-seq
MIRT1272786	hsa-miR-3678-3p	CLIP-seq
MIRT1272787	hsa-miR-3681	CLIP-seq
MIRT1272788	hsa-miR-375	CLIP-seq
MIRT1272789	hsa-miR-376c	CLIP-seq
MIRT1272790	hsa-miR-378	CLIP-seq
MIRT1272791	hsa-miR-378b	CLIP-seq
MIRT1272792	hsa-miR-378c	CLIP-seq
MIRT1272793	hsa-miR-378d	CLIP-seq
MIRT1272794	hsa-miR-378e	CLIP-seq
MIRT1272795	hsa-miR-378f	CLIP-seq
MIRT1272796	hsa-miR-378h	CLIP-seq
MIRT1272797	hsa-miR-378i	CLIP-seq
MIRT1272798	hsa-miR-3919	CLIP-seq
MIRT1272799	hsa-miR-3940-3p	CLIP-seq
MIRT1272800	hsa-miR-409-5p	CLIP-seq
MIRT1272801	hsa-miR-421	CLIP-seq
MIRT1272802	hsa-miR-422a	CLIP-seq
MIRT1272803	hsa-miR-4275	CLIP-seq
MIRT1272804	hsa-miR-4280	CLIP-seq
MIRT1272805	hsa-miR-4282	CLIP-seq
MIRT1272806	hsa-miR-4295	CLIP-seq
MIRT1272807	hsa-miR-4314	CLIP-seq
MIRT1272808	hsa-miR-433	CLIP-seq
MIRT1272809	hsa-miR-4428	CLIP-seq
MIRT1272810	hsa-miR-4436b-3p	CLIP-seq
MIRT1272811	hsa-miR-4446-5p	CLIP-seq
MIRT1272812	hsa-miR-4460	CLIP-seq
MIRT1272813	hsa-miR-4495	CLIP-seq
MIRT1272814	hsa-miR-454	CLIP-seq
MIRT1272815	hsa-miR-4638-3p	CLIP-seq
MIRT1272816	hsa-miR-4639-5p	CLIP-seq
MIRT1272817	hsa-miR-4645-3p	CLIP-seq
MIRT1272818	hsa-miR-4646-5p	CLIP-seq
MIRT1272819	hsa-miR-4659a-3p	CLIP-seq
MIRT1272820	hsa-miR-4659a-5p	CLIP-seq
MIRT1272821	hsa-miR-4659b-3p	CLIP-seq
MIRT1272822	hsa-miR-4659b-5p	CLIP-seq
MIRT1272823	hsa-miR-4662a-3p	CLIP-seq
MIRT1272824	hsa-miR-4666-3p	CLIP-seq
MIRT1272825	hsa-miR-4668-3p	CLIP-seq
MIRT1272826	hsa-miR-4670-3p	CLIP-seq
MIRT1272827	hsa-miR-4684-5p	CLIP-seq
MIRT1272828	hsa-miR-4690-3p	CLIP-seq
MIRT1272829	hsa-miR-4690-5p	CLIP-seq
MIRT1272830	hsa-miR-4691-3p	CLIP-seq
MIRT1272831	hsa-miR-4691-5p	CLIP-seq
MIRT1272832	hsa-miR-4697-3p	CLIP-seq
MIRT1272833	hsa-miR-4698	CLIP-seq
MIRT1272834	hsa-miR-4708-5p	CLIP-seq
MIRT1272835	hsa-miR-4720-3p	CLIP-seq
MIRT1272836	hsa-miR-4727-3p	CLIP-seq
MIRT1272837	hsa-miR-4735-3p	CLIP-seq
MIRT1272838	hsa-miR-4753-3p	CLIP-seq
MIRT1272839	hsa-miR-4755-5p	CLIP-seq
MIRT1272840	hsa-miR-4758-3p	CLIP-seq
MIRT1272841	hsa-miR-4761-3p	CLIP-seq
MIRT1272842	hsa-miR-4762-5p	CLIP-seq
MIRT1272843	hsa-miR-4768-5p	CLIP-seq
MIRT1272844	hsa-miR-4770	CLIP-seq
MIRT1272845	hsa-miR-4774-3p	CLIP-seq
MIRT1272846	hsa-miR-4776-3p	CLIP-seq
MIRT1272847	hsa-miR-4803	CLIP-seq
MIRT1272848	hsa-miR-5096	CLIP-seq
MIRT1272849	hsa-miR-510	CLIP-seq
MIRT1272850	hsa-miR-513a-3p	CLIP-seq
MIRT1272851	hsa-miR-513c	CLIP-seq
MIRT1272852	hsa-miR-514b-5p	CLIP-seq
MIRT1272853	hsa-miR-516a-3p	CLIP-seq
MIRT1272854	hsa-miR-568	CLIP-seq
MIRT1272855	hsa-miR-579	CLIP-seq
MIRT1272856	hsa-miR-590-3p	CLIP-seq
MIRT1272857	hsa-miR-619	CLIP-seq
MIRT1272858	hsa-miR-657	CLIP-seq
MIRT1272859	hsa-miR-873	CLIP-seq
MIRT1272742	hsa-miR-1273f	CLIP-seq
MIRT1272750	hsa-miR-143	CLIP-seq
MIRT1272834	hsa-miR-4708-5p	CLIP-seq
MIRT1272844	hsa-miR-4770	CLIP-seq
MIRT1272789	hsa-miR-376c	CLIP-seq
MIRT1272789	hsa-miR-376c	CLIP-seq
MIRT2080194	hsa-miR-106a	CLIP-seq
MIRT2080195	hsa-miR-106b	CLIP-seq
MIRT1272737	hsa-miR-1206	CLIP-seq
MIRT1272739	hsa-miR-1252	CLIP-seq
MIRT1272741	hsa-miR-1264	CLIP-seq
MIRT1272743	hsa-miR-129-5p	CLIP-seq
MIRT1272748	hsa-miR-137	CLIP-seq
MIRT1272749	hsa-miR-141	CLIP-seq
MIRT2080196	hsa-miR-145	CLIP-seq
MIRT1272754	hsa-miR-154	CLIP-seq
MIRT2080197	hsa-miR-17	CLIP-seq
MIRT1272760	hsa-miR-200a	CLIP-seq
MIRT2080198	hsa-miR-20a	CLIP-seq
MIRT2080199	hsa-miR-20b	CLIP-seq
MIRT1272762	hsa-miR-2467-3p	CLIP-seq
MIRT1272767	hsa-miR-302f	CLIP-seq
MIRT2080200	hsa-miR-3120-3p	CLIP-seq
MIRT1272769	hsa-miR-3135	CLIP-seq
MIRT1272770	hsa-miR-3140-5p	CLIP-seq
MIRT2080201	hsa-miR-3153	CLIP-seq
MIRT1272771	hsa-miR-3157-5p	CLIP-seq
MIRT1272772	hsa-miR-3160-5p	CLIP-seq
MIRT1272775	hsa-miR-3192	CLIP-seq
MIRT1272779	hsa-miR-338-5p	CLIP-seq
MIRT1272780	hsa-miR-3591-3p	CLIP-seq
MIRT1272781	hsa-miR-3591-5p	CLIP-seq
MIRT2080202	hsa-miR-3606	CLIP-seq
MIRT1272782	hsa-miR-3611	CLIP-seq
MIRT1272783	hsa-miR-3613-3p	CLIP-seq
MIRT1272786	hsa-miR-3678-3p	CLIP-seq
MIRT1272787	hsa-miR-3681	CLIP-seq
MIRT1272788	hsa-miR-375	CLIP-seq
MIRT1272789	hsa-miR-376c	CLIP-seq
MIRT1272799	hsa-miR-3940-3p	CLIP-seq
MIRT1272800	hsa-miR-409-5p	CLIP-seq
MIRT1272801	hsa-miR-421	CLIP-seq
MIRT1272803	hsa-miR-4275	CLIP-seq
MIRT1272805	hsa-miR-4282	CLIP-seq
MIRT2080203	hsa-miR-4307	CLIP-seq
MIRT1272807	hsa-miR-4314	CLIP-seq
MIRT1272808	hsa-miR-433	CLIP-seq
MIRT1272812	hsa-miR-4460	CLIP-seq
MIRT1272813	hsa-miR-4495	CLIP-seq
MIRT1272816	hsa-miR-4639-5p	CLIP-seq
MIRT1272818	hsa-miR-4646-5p	CLIP-seq
MIRT1272819	hsa-miR-4659a-3p	CLIP-seq
MIRT1272821	hsa-miR-4659b-3p	CLIP-seq
MIRT1272825	hsa-miR-4668-3p	CLIP-seq
MIRT2080204	hsa-miR-4668-5p	CLIP-seq
MIRT1272828	hsa-miR-4690-3p	CLIP-seq
MIRT1272829	hsa-miR-4690-5p	CLIP-seq
MIRT1272831	hsa-miR-4691-5p	CLIP-seq
MIRT2080205	hsa-miR-4704-3p	CLIP-seq
MIRT2080206	hsa-miR-4705	CLIP-seq
MIRT2080207	hsa-miR-4716-5p	CLIP-seq
MIRT1272835	hsa-miR-4720-3p	CLIP-seq
MIRT1272836	hsa-miR-4727-3p	CLIP-seq
MIRT2080208	hsa-miR-4733-5p	CLIP-seq
MIRT1272842	hsa-miR-4762-5p	CLIP-seq
MIRT1272843	hsa-miR-4768-5p	CLIP-seq
MIRT1272845	hsa-miR-4774-3p	CLIP-seq
MIRT2080209	hsa-miR-4786-3p	CLIP-seq
MIRT1272850	hsa-miR-513a-3p	CLIP-seq
MIRT1272851	hsa-miR-513c	CLIP-seq
MIRT1272852	hsa-miR-514b-5p	CLIP-seq
MIRT2080210	hsa-miR-518a-5p	CLIP-seq
MIRT2080211	hsa-miR-519a	CLIP-seq
MIRT2080212	hsa-miR-519b-3p	CLIP-seq
MIRT2080213	hsa-miR-519c-3p	CLIP-seq
MIRT2080214	hsa-miR-519d	CLIP-seq
MIRT2080215	hsa-miR-520g	CLIP-seq
MIRT2080216	hsa-miR-520h	CLIP-seq
MIRT2080217	hsa-miR-527	CLIP-seq
MIRT2080218	hsa-miR-548aa	CLIP-seq
MIRT2080219	hsa-miR-548ac	CLIP-seq
MIRT2080220	hsa-miR-548d-3p	CLIP-seq
MIRT2080221	hsa-miR-548z	CLIP-seq
MIRT1272854	hsa-miR-568	CLIP-seq
MIRT1272858	hsa-miR-657	CLIP-seq
MIRT2080222	hsa-miR-921	CLIP-seq
MIRT2080223	hsa-miR-93	CLIP-seq
MIRT2306505	hsa-miR-101	CLIP-seq
MIRT2080194	hsa-miR-106a	CLIP-seq
MIRT2080195	hsa-miR-106b	CLIP-seq
MIRT1272737	hsa-miR-1206	CLIP-seq
MIRT1272739	hsa-miR-1252	CLIP-seq
MIRT1272740	hsa-miR-125a-3p	CLIP-seq
MIRT1272741	hsa-miR-1264	CLIP-seq
MIRT2306506	hsa-miR-1283	CLIP-seq
MIRT1272746	hsa-miR-130a	CLIP-seq
MIRT1272747	hsa-miR-130b	CLIP-seq
MIRT2306507	hsa-miR-136	CLIP-seq
MIRT1272749	hsa-miR-141	CLIP-seq
MIRT2306508	hsa-miR-144	CLIP-seq
MIRT2080196	hsa-miR-145	CLIP-seq
MIRT1272751	hsa-miR-148a	CLIP-seq
MIRT1272752	hsa-miR-148b	CLIP-seq
MIRT1272753	hsa-miR-152	CLIP-seq
MIRT1272754	hsa-miR-154	CLIP-seq
MIRT2080197	hsa-miR-17	CLIP-seq
MIRT1272755	hsa-miR-186	CLIP-seq
MIRT1272756	hsa-miR-18a	CLIP-seq
MIRT1272757	hsa-miR-18b	CLIP-seq
MIRT1272758	hsa-miR-19a	CLIP-seq
MIRT1272759	hsa-miR-19b	CLIP-seq
MIRT1272760	hsa-miR-200a	CLIP-seq
MIRT2080198	hsa-miR-20a	CLIP-seq
MIRT2080199	hsa-miR-20b	CLIP-seq
MIRT1272762	hsa-miR-2467-3p	CLIP-seq
MIRT1272765	hsa-miR-301a	CLIP-seq
MIRT1272766	hsa-miR-301b	CLIP-seq
MIRT1272769	hsa-miR-3135	CLIP-seq
MIRT1272770	hsa-miR-3140-5p	CLIP-seq
MIRT2306509	hsa-miR-3146	CLIP-seq
MIRT2080201	hsa-miR-3153	CLIP-seq
MIRT1272771	hsa-miR-3157-5p	CLIP-seq
MIRT1272772	hsa-miR-3160-5p	CLIP-seq
MIRT1272775	hsa-miR-3192	CLIP-seq
MIRT1272776	hsa-miR-320e	CLIP-seq
MIRT1272779	hsa-miR-338-5p	CLIP-seq
MIRT1272780	hsa-miR-3591-3p	CLIP-seq
MIRT1272782	hsa-miR-3611	CLIP-seq
MIRT2306510	hsa-miR-3660	CLIP-seq
MIRT1272785	hsa-miR-3666	CLIP-seq
MIRT1272786	hsa-miR-3678-3p	CLIP-seq
MIRT1272789	hsa-miR-376c	CLIP-seq
MIRT1272790	hsa-miR-378	CLIP-seq
MIRT1272791	hsa-miR-378b	CLIP-seq
MIRT1272792	hsa-miR-378c	CLIP-seq
MIRT1272793	hsa-miR-378d	CLIP-seq
MIRT1272794	hsa-miR-378e	CLIP-seq
MIRT1272795	hsa-miR-378f	CLIP-seq
MIRT1272796	hsa-miR-378h	CLIP-seq
MIRT1272797	hsa-miR-378i	CLIP-seq
MIRT1272798	hsa-miR-3919	CLIP-seq
MIRT1272800	hsa-miR-409-5p	CLIP-seq
MIRT1272801	hsa-miR-421	CLIP-seq
MIRT1272802	hsa-miR-422a	CLIP-seq
MIRT1272806	hsa-miR-4295	CLIP-seq
MIRT1272807	hsa-miR-4314	CLIP-seq
MIRT1272808	hsa-miR-433	CLIP-seq
MIRT1272813	hsa-miR-4495	CLIP-seq
MIRT2306511	hsa-miR-4526	CLIP-seq
MIRT1272814	hsa-miR-454	CLIP-seq
MIRT1272815	hsa-miR-4638-3p	CLIP-seq
MIRT1272816	hsa-miR-4639-5p	CLIP-seq
MIRT1272817	hsa-miR-4645-3p	CLIP-seq
MIRT1272818	hsa-miR-4646-5p	CLIP-seq
MIRT1272819	hsa-miR-4659a-3p	CLIP-seq
MIRT1272820	hsa-miR-4659a-5p	CLIP-seq
MIRT1272821	hsa-miR-4659b-3p	CLIP-seq
MIRT1272822	hsa-miR-4659b-5p	CLIP-seq
MIRT1272823	hsa-miR-4662a-3p	CLIP-seq
MIRT1272825	hsa-miR-4668-3p	CLIP-seq
MIRT2080204	hsa-miR-4668-5p	CLIP-seq
MIRT1272826	hsa-miR-4670-3p	CLIP-seq
MIRT1272829	hsa-miR-4690-5p	CLIP-seq
MIRT1272830	hsa-miR-4691-3p	CLIP-seq
MIRT1272831	hsa-miR-4691-5p	CLIP-seq
MIRT2306512	hsa-miR-4694-3p	CLIP-seq
MIRT1272833	hsa-miR-4698	CLIP-seq
MIRT2080205	hsa-miR-4704-3p	CLIP-seq
MIRT2080206	hsa-miR-4705	CLIP-seq
MIRT2306513	hsa-miR-4712-5p	CLIP-seq
MIRT2080207	hsa-miR-4716-5p	CLIP-seq
MIRT1272835	hsa-miR-4720-3p	CLIP-seq
MIRT1272837	hsa-miR-4735-3p	CLIP-seq
MIRT1272842	hsa-miR-4762-5p	CLIP-seq
MIRT1272845	hsa-miR-4774-3p	CLIP-seq
MIRT1272846	hsa-miR-4776-3p	CLIP-seq
MIRT1272848	hsa-miR-5096	CLIP-seq
MIRT1272851	hsa-miR-513c	CLIP-seq
MIRT1272852	hsa-miR-514b-5p	CLIP-seq
MIRT2080210	hsa-miR-518a-5p	CLIP-seq
MIRT2080211	hsa-miR-519a	CLIP-seq
MIRT2080212	hsa-miR-519b-3p	CLIP-seq
MIRT2080213	hsa-miR-519c-3p	CLIP-seq
MIRT2080214	hsa-miR-519d	CLIP-seq
MIRT2080215	hsa-miR-520g	CLIP-seq
MIRT2080216	hsa-miR-520h	CLIP-seq
MIRT2306514	hsa-miR-522	CLIP-seq
MIRT2080217	hsa-miR-527	CLIP-seq
MIRT2306515	hsa-miR-548c-3p	CLIP-seq
MIRT1272855	hsa-miR-579	CLIP-seq
MIRT2306516	hsa-miR-582-5p	CLIP-seq
MIRT1272857	hsa-miR-619	CLIP-seq
MIRT1272858	hsa-miR-657	CLIP-seq
MIRT2306517	hsa-miR-770-5p	CLIP-seq
MIRT2080223	hsa-miR-93	CLIP-seq
MIRT1272761	hsa-miR-223	CLIP-seq
MIRT1272763	hsa-miR-2681	CLIP-seq
MIRT1272778	hsa-miR-337-3p	CLIP-seq
MIRT1272832	hsa-miR-4697-3p	CLIP-seq
MIRT1272853	hsa-miR-516a-3p	CLIP-seq
MIRT1272741	hsa-miR-1264	CLIP-seq
MIRT2306505	hsa-miR-101	CLIP-seq
MIRT1272739	hsa-miR-1252	CLIP-seq
MIRT1272743	hsa-miR-129-5p	CLIP-seq
MIRT1272744	hsa-miR-1296	CLIP-seq
MIRT2603815	hsa-miR-1305	CLIP-seq
MIRT1272746	hsa-miR-130a	CLIP-seq
MIRT1272747	hsa-miR-130b	CLIP-seq
MIRT2306507	hsa-miR-136	CLIP-seq
MIRT2306508	hsa-miR-144	CLIP-seq
MIRT2080196	hsa-miR-145	CLIP-seq
MIRT1272751	hsa-miR-148a	CLIP-seq
MIRT1272752	hsa-miR-148b	CLIP-seq
MIRT1272753	hsa-miR-152	CLIP-seq
MIRT1272756	hsa-miR-18a	CLIP-seq
MIRT1272757	hsa-miR-18b	CLIP-seq
MIRT1272758	hsa-miR-19a	CLIP-seq
MIRT1272759	hsa-miR-19b	CLIP-seq
MIRT1272764	hsa-miR-2909	CLIP-seq
MIRT1272765	hsa-miR-301a	CLIP-seq
MIRT1272766	hsa-miR-301b	CLIP-seq
MIRT2080200	hsa-miR-3120-3p	CLIP-seq
MIRT2603816	hsa-miR-3125	CLIP-seq
MIRT1272770	hsa-miR-3140-5p	CLIP-seq
MIRT1272771	hsa-miR-3157-5p	CLIP-seq
MIRT1272772	hsa-miR-3160-5p	CLIP-seq
MIRT1272776	hsa-miR-320e	CLIP-seq
MIRT2603817	hsa-miR-323-3p	CLIP-seq
MIRT1272777	hsa-miR-323b-3p	CLIP-seq
MIRT1272780	hsa-miR-3591-3p	CLIP-seq
MIRT1272781	hsa-miR-3591-5p	CLIP-seq
MIRT1272782	hsa-miR-3611	CLIP-seq
MIRT1272783	hsa-miR-3613-3p	CLIP-seq
MIRT1272785	hsa-miR-3666	CLIP-seq
MIRT2603818	hsa-miR-3671	CLIP-seq
MIRT1272787	hsa-miR-3681	CLIP-seq
MIRT1272788	hsa-miR-375	CLIP-seq
MIRT1272789	hsa-miR-376c	CLIP-seq
MIRT1272790	hsa-miR-378	CLIP-seq
MIRT1272791	hsa-miR-378b	CLIP-seq
MIRT1272792	hsa-miR-378c	CLIP-seq
MIRT1272793	hsa-miR-378d	CLIP-seq
MIRT1272794	hsa-miR-378e	CLIP-seq
MIRT1272795	hsa-miR-378f	CLIP-seq
MIRT1272796	hsa-miR-378h	CLIP-seq
MIRT1272797	hsa-miR-378i	CLIP-seq
MIRT2603819	hsa-miR-3916	CLIP-seq
MIRT1272799	hsa-miR-3940-3p	CLIP-seq
MIRT1272800	hsa-miR-409-5p	CLIP-seq
MIRT1272802	hsa-miR-422a	CLIP-seq
MIRT1272804	hsa-miR-4280	CLIP-seq
MIRT1272806	hsa-miR-4295	CLIP-seq
MIRT1272810	hsa-miR-4436b-3p	CLIP-seq
MIRT1272812	hsa-miR-4460	CLIP-seq
MIRT1272813	hsa-miR-4495	CLIP-seq
MIRT1272814	hsa-miR-454	CLIP-seq
MIRT1272815	hsa-miR-4638-3p	CLIP-seq
MIRT1272816	hsa-miR-4639-5p	CLIP-seq
MIRT1272817	hsa-miR-4645-3p	CLIP-seq
MIRT1272819	hsa-miR-4659a-3p	CLIP-seq
MIRT1272821	hsa-miR-4659b-3p	CLIP-seq
MIRT1272825	hsa-miR-4668-3p	CLIP-seq
MIRT1272828	hsa-miR-4690-3p	CLIP-seq
MIRT1272829	hsa-miR-4690-5p	CLIP-seq
MIRT1272830	hsa-miR-4691-3p	CLIP-seq
MIRT1272831	hsa-miR-4691-5p	CLIP-seq
MIRT2306512	hsa-miR-4694-3p	CLIP-seq
MIRT2080205	hsa-miR-4704-3p	CLIP-seq
MIRT2306513	hsa-miR-4712-5p	CLIP-seq
MIRT2080207	hsa-miR-4716-5p	CLIP-seq
MIRT1272835	hsa-miR-4720-3p	CLIP-seq
MIRT1272836	hsa-miR-4727-3p	CLIP-seq
MIRT2080208	hsa-miR-4733-5p	CLIP-seq
MIRT1272837	hsa-miR-4735-3p	CLIP-seq
MIRT1272841	hsa-miR-4761-3p	CLIP-seq
MIRT1272842	hsa-miR-4762-5p	CLIP-seq
MIRT1272847	hsa-miR-4803	CLIP-seq
MIRT1272850	hsa-miR-513a-3p	CLIP-seq
MIRT1272851	hsa-miR-513c	CLIP-seq
MIRT1272852	hsa-miR-514b-5p	CLIP-seq
MIRT2306514	hsa-miR-522	CLIP-seq
MIRT2080218	hsa-miR-548aa	CLIP-seq
MIRT2080219	hsa-miR-548ac	CLIP-seq
MIRT2306515	hsa-miR-548c-3p	CLIP-seq
MIRT2080220	hsa-miR-548d-3p	CLIP-seq
MIRT2080221	hsa-miR-548z	CLIP-seq
MIRT1272854	hsa-miR-568	CLIP-seq
MIRT2306516	hsa-miR-582-5p	CLIP-seq
MIRT1272856	hsa-miR-590-3p	CLIP-seq
MIRT2603820	hsa-miR-607	CLIP-seq
MIRT1272858	hsa-miR-657	CLIP-seq
MIRT2306517	hsa-miR-770-5p	CLIP-seq
MIRT1272739	hsa-miR-1252	CLIP-seq
MIRT1272743	hsa-miR-129-5p	CLIP-seq
MIRT2603815	hsa-miR-1305	CLIP-seq
MIRT1272746	hsa-miR-130a	CLIP-seq
MIRT1272747	hsa-miR-130b	CLIP-seq
MIRT2306507	hsa-miR-136	CLIP-seq
MIRT2080196	hsa-miR-145	CLIP-seq
MIRT1272751	hsa-miR-148a	CLIP-seq
MIRT1272752	hsa-miR-148b	CLIP-seq
MIRT1272753	hsa-miR-152	CLIP-seq
MIRT1272756	hsa-miR-18a	CLIP-seq
MIRT1272757	hsa-miR-18b	CLIP-seq
MIRT1272758	hsa-miR-19a	CLIP-seq
MIRT1272759	hsa-miR-19b	CLIP-seq
MIRT1272765	hsa-miR-301a	CLIP-seq
MIRT1272766	hsa-miR-301b	CLIP-seq
MIRT2080200	hsa-miR-3120-3p	CLIP-seq
MIRT2603816	hsa-miR-3125	CLIP-seq
MIRT1272770	hsa-miR-3140-5p	CLIP-seq
MIRT1272771	hsa-miR-3157-5p	CLIP-seq
MIRT1272772	hsa-miR-3160-5p	CLIP-seq
MIRT1272776	hsa-miR-320e	CLIP-seq
MIRT2603817	hsa-miR-323-3p	CLIP-seq
MIRT1272777	hsa-miR-323b-3p	CLIP-seq
MIRT1272780	hsa-miR-3591-3p	CLIP-seq
MIRT1272781	hsa-miR-3591-5p	CLIP-seq
MIRT2080202	hsa-miR-3606	CLIP-seq
MIRT1272782	hsa-miR-3611	CLIP-seq
MIRT1272783	hsa-miR-3613-3p	CLIP-seq
MIRT1272785	hsa-miR-3666	CLIP-seq
MIRT2603818	hsa-miR-3671	CLIP-seq
MIRT1272787	hsa-miR-3681	CLIP-seq
MIRT1272789	hsa-miR-376c	CLIP-seq
MIRT1272790	hsa-miR-378	CLIP-seq
MIRT1272791	hsa-miR-378b	CLIP-seq
MIRT1272792	hsa-miR-378c	CLIP-seq
MIRT1272793	hsa-miR-378d	CLIP-seq
MIRT1272794	hsa-miR-378e	CLIP-seq
MIRT1272795	hsa-miR-378f	CLIP-seq
MIRT1272796	hsa-miR-378h	CLIP-seq
MIRT1272797	hsa-miR-378i	CLIP-seq
MIRT2603819	hsa-miR-3916	CLIP-seq
MIRT1272799	hsa-miR-3940-3p	CLIP-seq
MIRT1272800	hsa-miR-409-5p	CLIP-seq
MIRT1272802	hsa-miR-422a	CLIP-seq
MIRT1272804	hsa-miR-4280	CLIP-seq
MIRT1272806	hsa-miR-4295	CLIP-seq
MIRT1272812	hsa-miR-4460	CLIP-seq
MIRT1272813	hsa-miR-4495	CLIP-seq
MIRT2688922	hsa-miR-4506	CLIP-seq
MIRT1272814	hsa-miR-454	CLIP-seq
MIRT1272815	hsa-miR-4638-3p	CLIP-seq
MIRT1272816	hsa-miR-4639-5p	CLIP-seq
MIRT1272817	hsa-miR-4645-3p	CLIP-seq
MIRT1272819	hsa-miR-4659a-3p	CLIP-seq
MIRT1272821	hsa-miR-4659b-3p	CLIP-seq
MIRT1272825	hsa-miR-4668-3p	CLIP-seq
MIRT1272828	hsa-miR-4690-3p	CLIP-seq
MIRT1272829	hsa-miR-4690-5p	CLIP-seq
MIRT1272830	hsa-miR-4691-3p	CLIP-seq
MIRT1272831	hsa-miR-4691-5p	CLIP-seq
MIRT2306512	hsa-miR-4694-3p	CLIP-seq
MIRT2306513	hsa-miR-4712-5p	CLIP-seq
MIRT1272835	hsa-miR-4720-3p	CLIP-seq
MIRT1272836	hsa-miR-4727-3p	CLIP-seq
MIRT2080208	hsa-miR-4733-5p	CLIP-seq
MIRT1272837	hsa-miR-4735-3p	CLIP-seq
MIRT1272842	hsa-miR-4762-5p	CLIP-seq
MIRT2080209	hsa-miR-4786-3p	CLIP-seq
MIRT1272847	hsa-miR-4803	CLIP-seq
MIRT2688923	hsa-miR-495	CLIP-seq
MIRT1272850	hsa-miR-513a-3p	CLIP-seq
MIRT1272851	hsa-miR-513c	CLIP-seq
MIRT1272852	hsa-miR-514b-5p	CLIP-seq
MIRT2306514	hsa-miR-522	CLIP-seq
MIRT2688924	hsa-miR-548a-5p	CLIP-seq
MIRT2080218	hsa-miR-548aa	CLIP-seq
MIRT2688925	hsa-miR-548ab	CLIP-seq
MIRT2080219	hsa-miR-548ac	CLIP-seq
MIRT2688926	hsa-miR-548ak	CLIP-seq
MIRT2688927	hsa-miR-548b-5p	CLIP-seq
MIRT2306515	hsa-miR-548c-3p	CLIP-seq
MIRT2688928	hsa-miR-548c-5p	CLIP-seq
MIRT2080220	hsa-miR-548d-3p	CLIP-seq
MIRT2688929	hsa-miR-548d-5p	CLIP-seq
MIRT2688930	hsa-miR-548h	CLIP-seq
MIRT2688931	hsa-miR-548i	CLIP-seq
MIRT2688932	hsa-miR-548j	CLIP-seq
MIRT2688933	hsa-miR-548k	CLIP-seq
MIRT2688934	hsa-miR-548l	CLIP-seq
MIRT2688935	hsa-miR-548w	CLIP-seq
MIRT2688936	hsa-miR-548y	CLIP-seq
MIRT2080221	hsa-miR-548z	CLIP-seq
MIRT2688937	hsa-miR-559	CLIP-seq
MIRT1272854	hsa-miR-568	CLIP-seq
MIRT1272856	hsa-miR-590-3p	CLIP-seq
MIRT2603820	hsa-miR-607	CLIP-seq
MIRT1272858	hsa-miR-657	CLIP-seq
MIRT2306517	hsa-miR-770-5p	CLIP-seq
MIRT2080222	hsa-miR-921	CLIP-seq

Show/Hide all (43)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000723	Process	Telomere maintenance	TAS	12135483
GO:0000781	Component	Chromosome, telomeric region	IC	12135483
GO:0001516	Process	Prostaglandin biosynthetic process	IBA
GO:0001516	Process	Prostaglandin biosynthetic process	IDA	10922363
GO:0001516	Process	Prostaglandin biosynthetic process	IEA
GO:0003720	Function	Telomerase activity	IDA	12135483
GO:0005515	Function	Protein binding	IPI	9817749, 19875381, 21183720, 21988832, 23741051, 25036637, 27353360, 33961781, 35271311, 35914814
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005634	Component	Nucleus	IBA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005697	Component	Telomerase holoenzyme complex	IDA	12135483
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	TAS
GO:0006457	Process	Protein folding	IBA
GO:0006457	Process	Protein folding	IDA	12853476
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IEA
GO:0006693	Process	Prostaglandin metabolic process	IEA
GO:0007004	Process	Telomere maintenance via telomerase	IBA
GO:0007004	Process	Telomere maintenance via telomerase	IDA	10197982
GO:0007165	Process	Signal transduction	TAS	8114727
GO:0016853	Function	Isomerase activity	IEA
GO:0032212	Process	Positive regulation of telomere maintenance via telomerase	IDA	19740745
GO:0032991	Component	Protein-containing complex	IMP	10543959, 10811660
GO:0046457	Process	Prostanoid biosynthetic process	TAS
GO:0050220	Function	Prostaglandin-E synthase activity	EXP	10922363
GO:0050220	Function	Prostaglandin-E synthase activity	IBA
GO:0050220	Function	Prostaglandin-E synthase activity	IDA	10922363
GO:0050220	Function	Prostaglandin-E synthase activity	IEA
GO:0050821	Process	Protein stabilization	IMP	10543959, 10811660
GO:0051082	Function	Unfolded protein binding	IDA	12077419
GO:0051087	Function	Protein-folding chaperone binding	IBA
GO:0051131	Process	Chaperone-mediated protein complex assembly	IBA
GO:0051131	Process	Chaperone-mediated protein complex assembly	IMP	10811660
GO:0051879	Function	Hsp90 protein binding	IBA
GO:0051879	Function	Hsp90 protein binding	IEA
GO:0051879	Function	Hsp90 protein binding	IPI	10543959, 10811660, 19740745
GO:0070182	Function	DNA polymerase binding	IPI	10197982, 19751963
GO:0101031	Component	Protein folding chaperone complex	IDA	29127155
GO:1905323	Process	Telomerase holoenzyme complex assembly	IBA
GO:1905323	Process	Telomerase holoenzyme complex assembly	IDA	10197982

MIM	HGNC	e!Ensembl
607061	16049	ENSG00000110958

Q15185

Protein name

Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)

Protein function

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manne

PDB

1EJF , 7KRJ , 7L7I , 7L7J

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04969	CS	4 → 79	CS domain	Domain

Sequence

MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID
PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF
DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE

Sequence length

160

Interactions

View interactions

	KEGG		Reactome
	Arachidonic acid metabolism Metabolic pathways Chemical carcinogenesis - receptor activation		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) HSP90 chaperone cycle for steroid hormone receptors (SHR) HSF1 activation Attenuation phase Aryl hydrocarbon receptor signalling ESR-mediated signaling Estrogen-dependent gene expression

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FIBRILLATION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATRIAL FLUTTER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (24)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Stimulate	35820363, 37416927	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	10207098, 16809759, 20847343, 22074947, 38245717	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Stimulate	37416927	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Associate	32116234	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cryptosporidiosis	Associate	22302851	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cystic Fibrosis	Associate	30661024	★★★★★ ★☆☆☆☆ Found in Text Mining only
Drug Related Side Effects and Adverse Reactions	Associate	30204910	★★★★★ ★☆☆☆☆ Found in Text Mining only
Endometriosis	Associate	24035605	★★★★★ ★☆☆☆☆ Found in Text Mining only
Graves Ophthalmopathy	Associate	36076300	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Stimulate	20847343	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Associate	20847343, 22074947, 25241147	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	16809759, 20847343, 25176350	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	37416927	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nephrosclerosis	Associate	36690661	★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Associate	28586048	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Associate	37831605	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	25241147	★★★★★ ★☆☆☆☆ Found in Text Mining only
Psychotic Disorders	Associate	24345775	★★★★★ ★☆☆☆☆ Found in Text Mining only
Sarcoma	Associate	15026814	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Stimulate	24345775	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ulcer	Associate	15531909	★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Associate	8524818	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Associate	36614304	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Diseases	Associate	24035605	★★★★★ ★☆☆☆☆ Found in Text Mining only

PTGES3 (prostaglandin E synthase 3)