B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2)

Gene

• Entrez ID: 10678
• Gene name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
• Gene symbol: B3GNT2
• Synonyms (NCBI Gene): 3-Gn-T1, 3-Gn-T2, B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT, BGNT2, BGnT-2, beta-1, beta3Gn-T1, beta3Gn-T2
• Chromosome: 2
• Chromosome location: 2p15
• Summary: This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022296	hsa-miR-124-3p	Microarray	18668037
MIRT023499	hsa-miR-1-3p	Microarray	18668037
MIRT303046	hsa-miR-10a-3p	PAR-CLIP	20371350
MIRT089117	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT089105	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT089110	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT089106	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT089111	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT089112	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT089113	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT089119	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT559277	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT089116	hsa-miR-3607-5p	PAR-CLIP	20371350
MIRT303049	hsa-miR-875-3p	PAR-CLIP	20371350
MIRT303052	hsa-miR-6128	PAR-CLIP	20371350
MIRT089115	hsa-miR-643	PAR-CLIP	20371350
MIRT089108	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT089109	hsa-miR-107	PAR-CLIP	20371350
MIRT089118	hsa-miR-6792-5p	PAR-CLIP	20371350
MIRT303051	hsa-miR-1299	PAR-CLIP	20371350
MIRT559276	hsa-miR-516b-5p	PAR-CLIP	20371350
MIRT559275	hsa-miR-4782-5p	PAR-CLIP	20371350
MIRT559274	hsa-miR-5706	PAR-CLIP	20371350
MIRT089114	hsa-miR-568	PAR-CLIP	20371350
MIRT559273	hsa-miR-1248	PAR-CLIP	20371350
MIRT303046	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT089117	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT303047	hsa-miR-590-3p	PAR-CLIP	21572407
MIRT303048	hsa-miR-888-5p	PAR-CLIP	21572407
MIRT089105	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT089110	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT089106	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT089111	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT089112	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT089113	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT089119	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT559277	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT089107	hsa-miR-95-5p	PAR-CLIP	21572407
MIRT089116	hsa-miR-3607-5p	PAR-CLIP	21572407
MIRT303049	hsa-miR-875-3p	PAR-CLIP	21572407
MIRT303052	hsa-miR-6128	PAR-CLIP	21572407
MIRT089115	hsa-miR-643	PAR-CLIP	21572407
MIRT089108	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT089109	hsa-miR-107	PAR-CLIP	21572407
MIRT089118	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT303051	hsa-miR-1299	PAR-CLIP	21572407
MIRT559276	hsa-miR-516b-5p	PAR-CLIP	21572407
MIRT559275	hsa-miR-4782-5p	PAR-CLIP	21572407
MIRT559274	hsa-miR-5706	PAR-CLIP	21572407
MIRT089114	hsa-miR-568	PAR-CLIP	21572407
MIRT559273	hsa-miR-1248	PAR-CLIP	21572407
MIRT481095	hsa-miR-24-3p	PAR-CLIP	23592263
MIRT303048	hsa-miR-888-5p	PAR-CLIP	23592263
MIRT481094	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT481093	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT481092	hsa-miR-4699-3p	PAR-CLIP	23592263
MIRT481091	hsa-miR-3919	PAR-CLIP	23592263
MIRT481090	hsa-miR-4756-3p	PAR-CLIP	23592263
MIRT481089	hsa-miR-2467-5p	PAR-CLIP	23592263
MIRT303046	hsa-miR-10a-3p	PAR-CLIP	20371350
MIRT089117	hsa-miR-5583-3p	PAR-CLIP	20371350
MIRT089105	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT089110	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT089106	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT089111	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT089112	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT089113	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT089119	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT559277	hsa-miR-183-5p	PAR-CLIP	20371350
MIRT089116	hsa-miR-3607-5p	PAR-CLIP	20371350
MIRT303049	hsa-miR-875-3p	PAR-CLIP	20371350
MIRT303052	hsa-miR-6128	PAR-CLIP	20371350
MIRT089115	hsa-miR-643	PAR-CLIP	20371350
MIRT089108	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT089109	hsa-miR-107	PAR-CLIP	20371350
MIRT089118	hsa-miR-6792-5p	PAR-CLIP	20371350
MIRT303051	hsa-miR-1299	PAR-CLIP	20371350
MIRT559276	hsa-miR-516b-5p	PAR-CLIP	20371350
MIRT559275	hsa-miR-4782-5p	PAR-CLIP	20371350
MIRT559274	hsa-miR-5706	PAR-CLIP	20371350
MIRT089114	hsa-miR-568	PAR-CLIP	20371350
MIRT559273	hsa-miR-1248	PAR-CLIP	20371350
MIRT303046	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT089117	hsa-miR-5583-3p	PAR-CLIP	21572407
MIRT303047	hsa-miR-590-3p	PAR-CLIP	21572407
MIRT303048	hsa-miR-888-5p	PAR-CLIP	21572407
MIRT089105	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT089110	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT089106	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT089111	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT089112	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT089113	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT089119	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT559277	hsa-miR-183-5p	PAR-CLIP	21572407
MIRT089107	hsa-miR-95-5p	PAR-CLIP	21572407
MIRT089116	hsa-miR-3607-5p	PAR-CLIP	21572407
MIRT303049	hsa-miR-875-3p	PAR-CLIP	21572407
MIRT303052	hsa-miR-6128	PAR-CLIP	21572407
MIRT089115	hsa-miR-643	PAR-CLIP	21572407
MIRT089108	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT089109	hsa-miR-107	PAR-CLIP	21572407
MIRT089118	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT303051	hsa-miR-1299	PAR-CLIP	21572407
MIRT559276	hsa-miR-516b-5p	PAR-CLIP	21572407
MIRT559275	hsa-miR-4782-5p	PAR-CLIP	21572407
MIRT559274	hsa-miR-5706	PAR-CLIP	21572407
MIRT089114	hsa-miR-568	PAR-CLIP	21572407
MIRT559273	hsa-miR-1248	PAR-CLIP	21572407
MIRT481095	hsa-miR-24-3p	PAR-CLIP	23592263
MIRT303048	hsa-miR-888-5p	PAR-CLIP	23592263
MIRT481094	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT481093	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT481092	hsa-miR-4699-3p	PAR-CLIP	23592263
MIRT481091	hsa-miR-3919	PAR-CLIP	23592263
MIRT481090	hsa-miR-4756-3p	PAR-CLIP	23592263
MIRT481089	hsa-miR-2467-5p	PAR-CLIP	23592263
MIRT813260	hsa-miR-103a	CLIP-seq
MIRT813261	hsa-miR-1207-5p	CLIP-seq
MIRT813262	hsa-miR-141	CLIP-seq
MIRT813263	hsa-miR-15a	CLIP-seq
MIRT813264	hsa-miR-15b	CLIP-seq
MIRT813265	hsa-miR-16	CLIP-seq
MIRT813266	hsa-miR-183	CLIP-seq
MIRT813267	hsa-miR-195	CLIP-seq
MIRT813268	hsa-miR-200a	CLIP-seq
MIRT813269	hsa-miR-300	CLIP-seq
MIRT813270	hsa-miR-3065-5p	CLIP-seq
MIRT813271	hsa-miR-3115	CLIP-seq
MIRT813272	hsa-miR-3140-5p	CLIP-seq
MIRT813273	hsa-miR-3147	CLIP-seq
MIRT813274	hsa-miR-3170	CLIP-seq
MIRT813275	hsa-miR-3180-5p	CLIP-seq
MIRT813276	hsa-miR-323b-5p	CLIP-seq
MIRT813277	hsa-miR-340	CLIP-seq
MIRT813278	hsa-miR-342-5p	CLIP-seq
MIRT813279	hsa-miR-3607-3p	CLIP-seq
MIRT813280	hsa-miR-3613-3p	CLIP-seq
MIRT813281	hsa-miR-3647-3p	CLIP-seq
MIRT813282	hsa-miR-3662	CLIP-seq
MIRT813283	hsa-miR-3686	CLIP-seq
MIRT813284	hsa-miR-3692	CLIP-seq
MIRT813285	hsa-miR-376c	CLIP-seq
MIRT813286	hsa-miR-381	CLIP-seq
MIRT813287	hsa-miR-3926	CLIP-seq
MIRT813288	hsa-miR-424	CLIP-seq
MIRT813289	hsa-miR-4269	CLIP-seq
MIRT813290	hsa-miR-4282	CLIP-seq
MIRT813291	hsa-miR-4321	CLIP-seq
MIRT813292	hsa-miR-4425	CLIP-seq
MIRT813293	hsa-miR-4464	CLIP-seq
MIRT813294	hsa-miR-4496	CLIP-seq
MIRT813295	hsa-miR-4528	CLIP-seq
MIRT813296	hsa-miR-4640-3p	CLIP-seq
MIRT813297	hsa-miR-4651	CLIP-seq
MIRT813298	hsa-miR-4664-5p	CLIP-seq
MIRT813299	hsa-miR-4666-3p	CLIP-seq
MIRT813300	hsa-miR-4680-3p	CLIP-seq
MIRT813301	hsa-miR-4704-3p	CLIP-seq
MIRT813302	hsa-miR-4704-5p	CLIP-seq
MIRT813303	hsa-miR-4733-3p	CLIP-seq
MIRT813304	hsa-miR-4736	CLIP-seq
MIRT813305	hsa-miR-4747-5p	CLIP-seq
MIRT813306	hsa-miR-4748	CLIP-seq
MIRT813307	hsa-miR-4763-3p	CLIP-seq
MIRT813308	hsa-miR-4795-3p	CLIP-seq
MIRT813309	hsa-miR-485-3p	CLIP-seq
MIRT813310	hsa-miR-497	CLIP-seq
MIRT813311	hsa-miR-513a-3p	CLIP-seq
MIRT813312	hsa-miR-520a-5p	CLIP-seq
MIRT813313	hsa-miR-520d-5p	CLIP-seq
MIRT813314	hsa-miR-524-5p	CLIP-seq
MIRT813315	hsa-miR-525-5p	CLIP-seq
MIRT813316	hsa-miR-548ac	CLIP-seq
MIRT813317	hsa-miR-548ae	CLIP-seq
MIRT813318	hsa-miR-548aj	CLIP-seq
MIRT813319	hsa-miR-548am	CLIP-seq
MIRT813320	hsa-miR-548d-3p	CLIP-seq
MIRT813321	hsa-miR-548s	CLIP-seq
MIRT813322	hsa-miR-548x	CLIP-seq
MIRT813323	hsa-miR-548z	CLIP-seq
MIRT813324	hsa-miR-584	CLIP-seq
MIRT813325	hsa-miR-608	CLIP-seq
MIRT813326	hsa-miR-656	CLIP-seq
MIRT813327	hsa-miR-888	CLIP-seq
MIRT813328	hsa-miR-935	CLIP-seq
MIRT813260	hsa-miR-103a	CLIP-seq
MIRT1940395	hsa-miR-133a	CLIP-seq
MIRT1940396	hsa-miR-133b	CLIP-seq
MIRT813263	hsa-miR-15a	CLIP-seq
MIRT813264	hsa-miR-15b	CLIP-seq
MIRT813265	hsa-miR-16	CLIP-seq
MIRT813267	hsa-miR-195	CLIP-seq
MIRT1940397	hsa-miR-2052	CLIP-seq
MIRT1940398	hsa-miR-2114	CLIP-seq
MIRT1940399	hsa-miR-2355-5p	CLIP-seq
MIRT1940400	hsa-miR-3163	CLIP-seq
MIRT1940401	hsa-miR-34c-3p	CLIP-seq
MIRT813281	hsa-miR-3647-3p	CLIP-seq
MIRT813282	hsa-miR-3662	CLIP-seq
MIRT813285	hsa-miR-376c	CLIP-seq
MIRT813287	hsa-miR-3926	CLIP-seq
MIRT813288	hsa-miR-424	CLIP-seq
MIRT1940402	hsa-miR-4307	CLIP-seq
MIRT1940403	hsa-miR-4484	CLIP-seq
MIRT813310	hsa-miR-497	CLIP-seq
MIRT1940404	hsa-miR-548an	CLIP-seq
MIRT813321	hsa-miR-548s	CLIP-seq
MIRT1940405	hsa-miR-587	CLIP-seq
MIRT813327	hsa-miR-888	CLIP-seq
MIRT813328	hsa-miR-935	CLIP-seq
MIRT813260	hsa-miR-103a	CLIP-seq
MIRT813261	hsa-miR-1207-5p	CLIP-seq
MIRT2179299	hsa-miR-1228	CLIP-seq
MIRT2179300	hsa-miR-1243	CLIP-seq
MIRT2179301	hsa-miR-1261	CLIP-seq
MIRT2179302	hsa-miR-1264	CLIP-seq
MIRT813262	hsa-miR-141	CLIP-seq
MIRT813263	hsa-miR-15a	CLIP-seq
MIRT813264	hsa-miR-15b	CLIP-seq
MIRT813265	hsa-miR-16	CLIP-seq
MIRT813266	hsa-miR-183	CLIP-seq
MIRT813267	hsa-miR-195	CLIP-seq
MIRT813268	hsa-miR-200a	CLIP-seq
MIRT2179303	hsa-miR-200b	CLIP-seq
MIRT2179304	hsa-miR-200c	CLIP-seq
MIRT1940398	hsa-miR-2114	CLIP-seq
MIRT1940399	hsa-miR-2355-5p	CLIP-seq
MIRT813269	hsa-miR-300	CLIP-seq
MIRT813270	hsa-miR-3065-5p	CLIP-seq
MIRT813271	hsa-miR-3115	CLIP-seq
MIRT813273	hsa-miR-3147	CLIP-seq
MIRT2179305	hsa-miR-3161	CLIP-seq
MIRT1940400	hsa-miR-3163	CLIP-seq
MIRT813274	hsa-miR-3170	CLIP-seq
MIRT2179306	hsa-miR-3187-3p	CLIP-seq
MIRT813276	hsa-miR-323b-5p	CLIP-seq
MIRT813278	hsa-miR-342-5p	CLIP-seq
MIRT2179307	hsa-miR-34b	CLIP-seq
MIRT2179308	hsa-miR-3616-3p	CLIP-seq
MIRT813281	hsa-miR-3647-3p	CLIP-seq
MIRT2179309	hsa-miR-3659	CLIP-seq
MIRT813284	hsa-miR-3692	CLIP-seq
MIRT813285	hsa-miR-376c	CLIP-seq
MIRT813286	hsa-miR-381	CLIP-seq
MIRT2179310	hsa-miR-409-3p	CLIP-seq
MIRT813288	hsa-miR-424	CLIP-seq
MIRT813289	hsa-miR-4269	CLIP-seq
MIRT2179311	hsa-miR-429	CLIP-seq
MIRT2179312	hsa-miR-4328	CLIP-seq
MIRT813292	hsa-miR-4425	CLIP-seq
MIRT2179313	hsa-miR-4435	CLIP-seq
MIRT2179314	hsa-miR-4477b	CLIP-seq
MIRT1940403	hsa-miR-4484	CLIP-seq
MIRT2179315	hsa-miR-450b-5p	CLIP-seq
MIRT2179316	hsa-miR-452	CLIP-seq
MIRT813295	hsa-miR-4528	CLIP-seq
MIRT2179317	hsa-miR-4529-5p	CLIP-seq
MIRT2179318	hsa-miR-4633-5p	CLIP-seq
MIRT813297	hsa-miR-4651	CLIP-seq
MIRT2179319	hsa-miR-4658	CLIP-seq
MIRT813298	hsa-miR-4664-5p	CLIP-seq
MIRT2179320	hsa-miR-4676-3p	CLIP-seq
MIRT2179321	hsa-miR-4698	CLIP-seq
MIRT2179322	hsa-miR-4701-5p	CLIP-seq
MIRT813301	hsa-miR-4704-3p	CLIP-seq
MIRT2179323	hsa-miR-4714-3p	CLIP-seq
MIRT2179324	hsa-miR-4715-5p	CLIP-seq
MIRT2179325	hsa-miR-4733-5p	CLIP-seq
MIRT813304	hsa-miR-4736	CLIP-seq
MIRT813305	hsa-miR-4747-5p	CLIP-seq
MIRT813307	hsa-miR-4763-3p	CLIP-seq
MIRT813308	hsa-miR-4795-3p	CLIP-seq
MIRT2179326	hsa-miR-4803	CLIP-seq
MIRT2179327	hsa-miR-495	CLIP-seq
MIRT813310	hsa-miR-497	CLIP-seq
MIRT2179328	hsa-miR-499-3p	CLIP-seq
MIRT2179329	hsa-miR-499a-3p	CLIP-seq
MIRT2179330	hsa-miR-507	CLIP-seq
MIRT2179331	hsa-miR-5096	CLIP-seq
MIRT813311	hsa-miR-513a-3p	CLIP-seq
MIRT2179332	hsa-miR-518a-5p	CLIP-seq
MIRT2179333	hsa-miR-527	CLIP-seq
MIRT2179334	hsa-miR-532-5p	CLIP-seq
MIRT2179335	hsa-miR-548aa	CLIP-seq
MIRT813316	hsa-miR-548ac	CLIP-seq
MIRT813317	hsa-miR-548ae	CLIP-seq
MIRT813318	hsa-miR-548aj	CLIP-seq
MIRT813319	hsa-miR-548am	CLIP-seq
MIRT1940404	hsa-miR-548an	CLIP-seq
MIRT813320	hsa-miR-548d-3p	CLIP-seq
MIRT813321	hsa-miR-548s	CLIP-seq
MIRT813322	hsa-miR-548x	CLIP-seq
MIRT813323	hsa-miR-548z	CLIP-seq
MIRT2179336	hsa-miR-549	CLIP-seq
MIRT2179337	hsa-miR-557	CLIP-seq
MIRT2179338	hsa-miR-574-5p	CLIP-seq
MIRT2179339	hsa-miR-577	CLIP-seq
MIRT813324	hsa-miR-584	CLIP-seq
MIRT1940405	hsa-miR-587	CLIP-seq
MIRT2179340	hsa-miR-588	CLIP-seq
MIRT2179341	hsa-miR-591	CLIP-seq
MIRT2179342	hsa-miR-597	CLIP-seq
MIRT813325	hsa-miR-608	CLIP-seq
MIRT813326	hsa-miR-656	CLIP-seq
MIRT813327	hsa-miR-888	CLIP-seq
MIRT813328	hsa-miR-935	CLIP-seq
MIRT813285	hsa-miR-376c	CLIP-seq
MIRT813289	hsa-miR-4269	CLIP-seq
MIRT813300	hsa-miR-4680-3p	CLIP-seq
MIRT813327	hsa-miR-888	CLIP-seq
MIRT813328	hsa-miR-935	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IBA
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	TAS
GO:0005515	Function	Protein binding	IPI	18826941, 33961781
GO:0005794	Component	Golgi apparatus	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0006493	Process	Protein O-linked glycosylation	IBA
GO:0007411	Process	Axon guidance	IEA
GO:0007608	Process	Sensory perception of smell	IEA
GO:0008499	Function	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	TAS
GO:0008532	Function	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	IBA
GO:0008532	Function	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	IDA	9892646, 11042166, 25279697
GO:0008532	Function	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	IEA
GO:0008532	Function	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	TAS
GO:0016020	Component	Membrane	IEA
GO:0016266	Process	Protein O-linked glycosylation via N-acetyl-galactosamine	TAS
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0016758	Function	Hexosyltransferase activity	IEA
GO:0018146	Process	Keratan sulfate proteoglycan biosynthetic process	TAS
GO:0030311	Process	Poly-N-acetyllactosamine biosynthetic process	IBA
GO:0030311	Process	Poly-N-acetyllactosamine biosynthetic process	IDA	9892646, 11042166, 25279697
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA

Other IDs

• MIM: 605581
• HGNC: 15629
• e!Ensembl: ENSG00000170340

Protein

• UniProt ID: Q9NY97
• Protein name: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (EC 2.4.1.149) (Beta-1,3-N-acetylglucosaminyltransferase 1) (BGnT-1) (Beta-1,3-Gn-T1) (Beta3Gn-T1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (Beta3GalT7) (b3Gal-T
• Protein function: Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMe
• PDB: 6WMM, 6WMN, 6WMO, 7JHK, 7JHL, 7JHM, 7JHN, 7JHO, 8SZ3, 8TIC, 8TJC
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01762	Galactosyl_T	156 → 351	Galactosyltransferase	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:11042166}.
• Sequence:

  MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWN
  REQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFL
  LYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVF
  LLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEF
  VFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLY
  PPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEE
  KNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC

• Sequence length: 397

Pathways

KEGG:

Glycosaminoglycan biosynthesis - keratan sulfate
Glycosphingolipid biosynthesis - lacto and neolacto series
Metabolic pathways

Reactome:

Keratan sulfate biosynthesis
O-linked glycosylation of mucins

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
B3GNT2-related disorder	Likely benign; Benign	rs144486810, rs547861725, rs530600752, rs72893877	RCV003981563 RCV003974205 RCV003962087 RCV003910380

Associations from Text Mining
Disease Name	Relationship Type	References
Arthritis Rheumatoid	Associate	23577190, 23904455
Autoimmune Diseases	Associate	23904455
Carcinogenesis	Stimulate	35073841
Carcinoma Hepatocellular	Associate	25605193
Colonic Neoplasms	Associate	27004849
Colorectal Neoplasms	Associate	15620693, 27004849
Esophageal Neoplasms	Associate	35073841
Genetic Diseases Inborn	Associate	33494994
Glioblastoma	Associate	27871300
Graves Disease	Associate	23904455
Hemoglobin SC Disease	Associate	24998922
Hypomagnesemia primary	Associate	24998922
Muscular Dystrophies	Associate	25353622
Neoplasms	Inhibit	19587235
Neoplasms	Associate	35073841
Schizophrenia	Associate	23904455
Spondylitis Ankylosing	Associate	34645591, 39468794
Uveal melanoma	Associate	18385798