Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10666
Gene name Gene Name - the full gene name approved by the HGNC.	CD226 molecule
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CD226
Synonyms (NCBI Gene) Gene synonyms aliases	DNAM-1, DNAM1, PTA1, TLiSA1
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18q22.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and me

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018110	hsa-miR-335-5p	Microarray	18185580
MIRT715737	hsa-miR-6830-3p	HITS-CLIP	19536157
MIRT715736	hsa-miR-511-5p	HITS-CLIP	19536157
MIRT715735	hsa-miR-2681-5p	HITS-CLIP	19536157
MIRT525272	hsa-miR-548a-3p	HITS-CLIP	21572407
MIRT525271	hsa-miR-548ar-3p	HITS-CLIP	21572407
MIRT525270	hsa-miR-548az-3p	HITS-CLIP	21572407
MIRT525269	hsa-miR-548e-3p	HITS-CLIP	21572407
MIRT525268	hsa-miR-548f-3p	HITS-CLIP	21572407
MIRT525267	hsa-miR-5582-3p	HITS-CLIP	21572407
MIRT508264	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508263	hsa-miR-4495	HITS-CLIP	21572407
MIRT508262	hsa-miR-379-3p	HITS-CLIP	21572407
MIRT508261	hsa-miR-411-3p	HITS-CLIP	21572407
MIRT508260	hsa-miR-380-3p	HITS-CLIP	21572407
MIRT508258	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508256	hsa-miR-3924	HITS-CLIP	21572407
MIRT508255	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT671143	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT671142	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT671141	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT671140	hsa-miR-1267	HITS-CLIP	23824327
MIRT671139	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT671138	hsa-miR-4294	HITS-CLIP	23824327
MIRT671137	hsa-miR-363-5p	HITS-CLIP	23824327
MIRT671136	hsa-miR-6745	HITS-CLIP	23824327
MIRT671135	hsa-miR-6880-5p	HITS-CLIP	23824327
MIRT671134	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT671133	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT671132	hsa-miR-3672	HITS-CLIP	23824327
MIRT671131	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT671130	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT671129	hsa-miR-8055	HITS-CLIP	23824327
MIRT671128	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT617150	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617148	hsa-miR-6516-3p	HITS-CLIP	23824327
MIRT617147	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT617146	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT617145	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT659692	hsa-miR-1299	HITS-CLIP	23824327
MIRT617144	hsa-miR-516b-5p	HITS-CLIP	23824327
MIRT659691	hsa-miR-4782-5p	HITS-CLIP	23824327
MIRT659690	hsa-miR-5706	HITS-CLIP	23824327
MIRT639080	hsa-miR-132-3p	HITS-CLIP	23824327
MIRT639079	hsa-miR-212-3p	HITS-CLIP	23824327
MIRT639078	hsa-miR-4709-5p	HITS-CLIP	23824327
MIRT639077	hsa-miR-16-1-3p	HITS-CLIP	23824327
MIRT639076	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT639075	hsa-miR-7159-5p	HITS-CLIP	23824327
MIRT639074	hsa-miR-505-3p	HITS-CLIP	23824327
MIRT639073	hsa-miR-421	HITS-CLIP	23824327
MIRT639072	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT639071	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT639070	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT617150	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617149	hsa-miR-630	HITS-CLIP	23824327
MIRT617148	hsa-miR-6516-3p	HITS-CLIP	23824327
MIRT617147	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT617146	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT617145	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT617144	hsa-miR-516b-5p	HITS-CLIP	23824327
MIRT508264	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT508263	hsa-miR-4495	PAR-CLIP	20371350
MIRT508262	hsa-miR-379-3p	PAR-CLIP	20371350
MIRT508261	hsa-miR-411-3p	PAR-CLIP	20371350
MIRT508260	hsa-miR-380-3p	PAR-CLIP	20371350
MIRT508257	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT508258	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT508256	hsa-miR-3924	PAR-CLIP	20371350
MIRT508255	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT525272	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT525271	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT525270	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT525269	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT525268	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT525267	hsa-miR-5582-3p	PAR-CLIP	22012620
MIRT508264	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT508263	hsa-miR-4495	PAR-CLIP	22012620
MIRT508262	hsa-miR-379-3p	PAR-CLIP	22012620
MIRT508261	hsa-miR-411-3p	PAR-CLIP	22012620
MIRT508260	hsa-miR-380-3p	PAR-CLIP	22012620
MIRT508258	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT508256	hsa-miR-3924	PAR-CLIP	22012620
MIRT508255	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT525266	hsa-miR-4640-3p	PAR-CLIP	22012620
MIRT525265	hsa-miR-323b-3p	PAR-CLIP	22012620
MIRT525264	hsa-miR-6793-3p	PAR-CLIP	22012620
MIRT525263	hsa-miR-6798-3p	PAR-CLIP	22012620
MIRT508264	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508263	hsa-miR-4495	PAR-CLIP	23446348
MIRT508262	hsa-miR-379-3p	PAR-CLIP	23446348
MIRT508261	hsa-miR-411-3p	PAR-CLIP	23446348
MIRT508260	hsa-miR-380-3p	PAR-CLIP	23446348
MIRT508259	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT508257	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT508258	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508256	hsa-miR-3924	PAR-CLIP	23446348
MIRT508255	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT733325	hsa-miR-145-5p	Immunofluorescence, Immunoprecipitaion (IP), In situ hybridization, Luciferase reporter assay, Western blotting	33859759
MIRT715737	hsa-miR-6830-3p	HITS-CLIP	19536157
MIRT715736	hsa-miR-511-5p	HITS-CLIP	19536157
MIRT715735	hsa-miR-2681-5p	HITS-CLIP	19536157
MIRT525272	hsa-miR-548a-3p	HITS-CLIP	21572407
MIRT525271	hsa-miR-548ar-3p	HITS-CLIP	21572407
MIRT525270	hsa-miR-548az-3p	HITS-CLIP	21572407
MIRT525269	hsa-miR-548e-3p	HITS-CLIP	21572407
MIRT525268	hsa-miR-548f-3p	HITS-CLIP	21572407
MIRT525267	hsa-miR-5582-3p	HITS-CLIP	21572407
MIRT508264	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508263	hsa-miR-4495	HITS-CLIP	21572407
MIRT508262	hsa-miR-379-3p	HITS-CLIP	21572407
MIRT508261	hsa-miR-411-3p	HITS-CLIP	21572407
MIRT508260	hsa-miR-380-3p	HITS-CLIP	21572407
MIRT508258	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508256	hsa-miR-3924	HITS-CLIP	21572407
MIRT508255	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT671143	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT671142	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT671141	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT671140	hsa-miR-1267	HITS-CLIP	23824327
MIRT671139	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT671138	hsa-miR-4294	HITS-CLIP	23824327
MIRT671137	hsa-miR-363-5p	HITS-CLIP	23824327
MIRT671136	hsa-miR-6745	HITS-CLIP	23824327
MIRT671135	hsa-miR-6880-5p	HITS-CLIP	23824327
MIRT671134	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT671133	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT671132	hsa-miR-3672	HITS-CLIP	23824327
MIRT671131	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT671130	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT671129	hsa-miR-8055	HITS-CLIP	23824327
MIRT671128	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT617150	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617148	hsa-miR-6516-3p	HITS-CLIP	23824327
MIRT617147	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT617146	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT617145	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT659692	hsa-miR-1299	HITS-CLIP	23824327
MIRT617144	hsa-miR-516b-5p	HITS-CLIP	23824327
MIRT659691	hsa-miR-4782-5p	HITS-CLIP	23824327
MIRT659690	hsa-miR-5706	HITS-CLIP	23824327
MIRT639080	hsa-miR-132-3p	HITS-CLIP	23824327
MIRT639079	hsa-miR-212-3p	HITS-CLIP	23824327
MIRT639078	hsa-miR-4709-5p	HITS-CLIP	23824327
MIRT639077	hsa-miR-16-1-3p	HITS-CLIP	23824327
MIRT639076	hsa-miR-676-5p	HITS-CLIP	23824327
MIRT639075	hsa-miR-7159-5p	HITS-CLIP	23824327
MIRT639074	hsa-miR-505-3p	HITS-CLIP	23824327
MIRT639073	hsa-miR-421	HITS-CLIP	23824327
MIRT639072	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT639071	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT639070	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT617150	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT617149	hsa-miR-630	HITS-CLIP	23824327
MIRT617148	hsa-miR-6516-3p	HITS-CLIP	23824327
MIRT617147	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT617146	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT617145	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT617144	hsa-miR-516b-5p	HITS-CLIP	23824327
MIRT508264	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT508263	hsa-miR-4495	PAR-CLIP	20371350
MIRT508262	hsa-miR-379-3p	PAR-CLIP	20371350
MIRT508261	hsa-miR-411-3p	PAR-CLIP	20371350
MIRT508260	hsa-miR-380-3p	PAR-CLIP	20371350
MIRT508257	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT508258	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT508256	hsa-miR-3924	PAR-CLIP	20371350
MIRT508255	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT525272	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT525271	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT525270	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT525269	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT525268	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT525267	hsa-miR-5582-3p	PAR-CLIP	22012620
MIRT508264	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT508263	hsa-miR-4495	PAR-CLIP	22012620
MIRT508262	hsa-miR-379-3p	PAR-CLIP	22012620
MIRT508261	hsa-miR-411-3p	PAR-CLIP	22012620
MIRT508260	hsa-miR-380-3p	PAR-CLIP	22012620
MIRT508258	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT508256	hsa-miR-3924	PAR-CLIP	22012620
MIRT508255	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT525266	hsa-miR-4640-3p	PAR-CLIP	22012620
MIRT525265	hsa-miR-323b-3p	PAR-CLIP	22012620
MIRT525264	hsa-miR-6793-3p	PAR-CLIP	22012620
MIRT525263	hsa-miR-6798-3p	PAR-CLIP	22012620
MIRT508264	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508263	hsa-miR-4495	PAR-CLIP	23446348
MIRT508262	hsa-miR-379-3p	PAR-CLIP	23446348
MIRT508261	hsa-miR-411-3p	PAR-CLIP	23446348
MIRT508260	hsa-miR-380-3p	PAR-CLIP	23446348
MIRT508259	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT508257	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT508258	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508256	hsa-miR-3924	PAR-CLIP	23446348
MIRT508255	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT874154	hsa-miR-3182	CLIP-seq
MIRT874155	hsa-miR-378	CLIP-seq
MIRT874156	hsa-miR-378b	CLIP-seq
MIRT874157	hsa-miR-378c	CLIP-seq
MIRT874158	hsa-miR-378d	CLIP-seq
MIRT874159	hsa-miR-378e	CLIP-seq
MIRT874160	hsa-miR-378f	CLIP-seq
MIRT874161	hsa-miR-378h	CLIP-seq
MIRT874162	hsa-miR-378i	CLIP-seq
MIRT874163	hsa-miR-422a	CLIP-seq
MIRT874164	hsa-miR-4638-3p	CLIP-seq
MIRT874165	hsa-miR-4678	CLIP-seq
MIRT874166	hsa-miR-4728-3p	CLIP-seq
MIRT874167	hsa-miR-4777-5p	CLIP-seq
MIRT874168	hsa-miR-516b	CLIP-seq
MIRT874169	hsa-miR-518d-5p	CLIP-seq
MIRT874170	hsa-miR-519b-5p	CLIP-seq
MIRT874171	hsa-miR-519c-5p	CLIP-seq
MIRT874172	hsa-miR-520c-5p	CLIP-seq
MIRT874173	hsa-miR-526a	CLIP-seq
MIRT1959218	hsa-miR-219-2-3p	CLIP-seq
MIRT1959219	hsa-miR-2964a-3p	CLIP-seq
MIRT1959220	hsa-miR-371-5p	CLIP-seq
MIRT1959221	hsa-miR-371b-5p	CLIP-seq
MIRT1959222	hsa-miR-411	CLIP-seq
MIRT1959223	hsa-miR-4680-3p	CLIP-seq
MIRT1959224	hsa-miR-513c	CLIP-seq
MIRT1959225	hsa-miR-514b-5p	CLIP-seq
MIRT1959226	hsa-miR-548n	CLIP-seq
MIRT2196250	hsa-miR-34b	CLIP-seq
MIRT1959220	hsa-miR-371-5p	CLIP-seq
MIRT1959221	hsa-miR-371b-5p	CLIP-seq
MIRT1959222	hsa-miR-411	CLIP-seq
MIRT2196251	hsa-miR-4418	CLIP-seq
MIRT2196252	hsa-miR-509-3-5p	CLIP-seq
MIRT2196253	hsa-miR-509-5p	CLIP-seq
MIRT1959224	hsa-miR-513c	CLIP-seq
MIRT1959225	hsa-miR-514b-5p	CLIP-seq
MIRT1959226	hsa-miR-548n	CLIP-seq
MIRT1959220	hsa-miR-371-5p	CLIP-seq
MIRT1959221	hsa-miR-371b-5p	CLIP-seq
MIRT1959222	hsa-miR-411	CLIP-seq
MIRT1959224	hsa-miR-513c	CLIP-seq
MIRT1959225	hsa-miR-514b-5p	CLIP-seq
MIRT1959226	hsa-miR-548n	CLIP-seq
MIRT1959220	hsa-miR-371-5p	CLIP-seq
MIRT1959221	hsa-miR-371b-5p	CLIP-seq
MIRT1959222	hsa-miR-411	CLIP-seq
MIRT1959224	hsa-miR-513c	CLIP-seq
MIRT1959225	hsa-miR-514b-5p	CLIP-seq
MIRT1959226	hsa-miR-548n	CLIP-seq
MIRT1959220	hsa-miR-371-5p	CLIP-seq
MIRT1959221	hsa-miR-371b-5p	CLIP-seq
MIRT1959222	hsa-miR-411	CLIP-seq
MIRT1959224	hsa-miR-513c	CLIP-seq
MIRT1959225	hsa-miR-514b-5p	CLIP-seq
MIRT1959226	hsa-miR-548n	CLIP-seq
MIRT2465055	hsa-miR-4517	CLIP-seq
MIRT2465056	hsa-miR-4712-3p	CLIP-seq
MIRT2465057	hsa-miR-577	CLIP-seq
MIRT2465058	hsa-miR-580	CLIP-seq
MIRT1959220	hsa-miR-371-5p	CLIP-seq
MIRT1959221	hsa-miR-371b-5p	CLIP-seq
MIRT1959222	hsa-miR-411	CLIP-seq
MIRT1959224	hsa-miR-513c	CLIP-seq
MIRT1959225	hsa-miR-514b-5p	CLIP-seq
MIRT1959226	hsa-miR-548n	CLIP-seq
MIRT1959220	hsa-miR-371-5p	CLIP-seq
MIRT1959221	hsa-miR-371b-5p	CLIP-seq
MIRT1959222	hsa-miR-411	CLIP-seq
MIRT2465055	hsa-miR-4517	CLIP-seq
MIRT2465056	hsa-miR-4712-3p	CLIP-seq
MIRT1959224	hsa-miR-513c	CLIP-seq
MIRT1959225	hsa-miR-514b-5p	CLIP-seq
MIRT1959226	hsa-miR-548n	CLIP-seq
MIRT2465057	hsa-miR-577	CLIP-seq
MIRT2465058	hsa-miR-580	CLIP-seq

Show/Hide all(33)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002729	Process	Positive regulation of natural killer cell cytokine production	IEA
GO:0002729	Process	Positive regulation of natural killer cell cytokine production	IEA
GO:0002860	Process	Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IMP	12913096
GO:0002891	Process	Positive regulation of immunoglobulin mediated immune response	IBA
GO:0002891	Process	Positive regulation of immunoglobulin mediated immune response	IDA	16831868
GO:0005178	Function	Integrin binding	IPI	16831868
GO:0005515	Function	Protein binding	IPI	21982860, 25465800, 26755705, 30591568
GO:0005886	Component	Plasma membrane	IC	15039383
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	8673704
GO:0007155	Process	Cell adhesion	IEA
GO:0007155	Process	Cell adhesion	TAS	8673704
GO:0007165	Process	Signal transduction	TAS	8673704
GO:0008037	Process	Cell recognition	TAS	16304049
GO:0009897	Component	External side of plasma membrane	IBA
GO:0009897	Component	External side of plasma membrane	IEA
GO:0009986	Component	Cell surface	IDA	16831868
GO:0016020	Component	Membrane	IEA
GO:0019901	Function	Protein kinase binding	IPI	16831868
GO:0032729	Process	Positive regulation of type II interferon production	IEA
GO:0033005	Process	Positive regulation of mast cell activation	IDA	16831868
GO:0038023	Function	Signaling receptor activity	IDA	15039383
GO:0042267	Process	Natural killer cell mediated cytotoxicity	IDA	16582911
GO:0042267	Process	Natural killer cell mediated cytotoxicity	IDA	8673704
GO:0042802	Function	Identical protein binding	IPI	25465800, 30591568
GO:0045121	Component	Membrane raft	TAS	16831868
GO:0045954	Process	Positive regulation of natural killer cell mediated cytotoxicity	IMP	16304049
GO:0050839	Function	Cell adhesion molecule binding	IBA
GO:0050839	Function	Cell adhesion molecule binding	IPI	12913096
GO:0050862	Process	Positive regulation of T cell receptor signaling pathway	IBA
GO:0050862	Process	Positive regulation of T cell receptor signaling pathway	IMP	26755705
GO:0060369	Process	Positive regulation of Fc receptor mediated stimulatory signaling pathway	IBA
GO:0060369	Process	Positive regulation of Fc receptor mediated stimulatory signaling pathway	IDA	16831868

MIM	HGNC	e!Ensembl
605397	16961	ENSG00000150637

Protein

UniProt ID

Q15762

Protein name

CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)

Protein function

Cell surface receptor that plays an important role in the immune system, particularly in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-cells and NK cells (PubMed:8673704, PubMed:97120

PDB

6ISB , 6O3O

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07686	V-set	24 → 126	Immunoglobulin V-set domain	Domain
PF07686	V-set	136 → 241	Immunoglobulin V-set domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed by peripheral blood T-lymphocytes. {ECO:0000269|PubMed:8673704}.

Sequence

MDYPTLLLALLHVYRALCEEVLWHTSVPFAENMSLECVYPSMGILTQVEWFKIGTQQDSI
AIFSPTHGMVIRKPYAERVYFLNSTMASNNMTLFFRNASEDDVGYYSCSLYTYPQGTWQK
VIQVVQSDSFEAAVPSNSHIVSEPGKNVTLTCQPQMTWPVQAVRWEKIQPRQIDLLTYCN
LVHGRNFTSKFPRQIVSNCSHGRWSVIVIPDVTVSDSGLYRCYLQASAGENETFVMRLTV
AEGKTDNQYTLFVAGGTVLLLLFVISITTIIVIFLNRRRRRERRDLFTESWDTQKAPNNY
RSPISTSQPTNQSMDDTREDIYVNYPTFSRRPKTRV

Sequence length

336

Interactions

View interactions

	KEGG		Reactome
	Cell adhesion molecules		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Show/Hide Unknown Diseases (9)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Biliary Cholangitis	Primary biliary cholangitis	N/A	N/A	GWAS
Diabetes	Type 1 diabetes	N/A	N/A	GWAS
Hypothyroidism	Hypothyroidism	N/A	N/A	GWAS
Inflammatory Bowel Disease	Inflammatory bowel disease	N/A	N/A	GWAS
Multiple Sclerosis	Multiple sclerosis	N/A	N/A	GWAS
Rheumatoid arthritis	Rheumatoid arthritis	N/A	N/A	GWAS
Sclerosing Cholangitis	Primary sclerosing cholangitis	N/A	N/A	GWAS
Systemic lupus erythematosus	Systemic lupus erythematosus	N/A	N/A	GWAS
Ulcerative colitis	Ulcerative colitis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (85)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Antiphospholipid Syndrome	Associate	38386917
Arthritis Psoriatic	Associate	33452865
Arthritis Rheumatoid	Associate	18971939, 20444755, 21765104, 23999715, 24673109
Asthma	Associate	16210593
Autoimmune Diseases	Associate	18971939, 20072139, 22427644, 22531499, 23980210, 35693814, 35971920
Autoimmune Diseases of the Nervous System	Associate	35733922
Breast Neoplasms	Associate	33549054
Carcinoma Hepatocellular	Associate	19404979, 22457290, 26936487
Carcinoma Non Small Cell Lung	Associate	35263569
Carcinoma Ovarian Epithelial	Associate	26563374
Carcinoma Pancreatic Ductal	Associate	31024520
Carcinoma Renal Cell	Stimulate	34149719
CD59 Deficiency	Associate	39231385
Colorectal Neoplasms	Inhibit	22189020
Colorectal Neoplasms	Associate	36717657
Corticosteroid Binding Globulin Deficiency	Associate	33584705
Dermatomyositis	Inhibit	2168821
Dermatomyositis	Associate	33413573
Diabetes Mellitus Type 1	Associate	18971939, 20089178, 21765104, 22403184, 24210274, 24891767, 35812428
Diabetes Mellitus Type 1	Stimulate	32035746
Drug Hypersensitivity	Associate	16210593
Drug Related Side Effects and Adverse Reactions	Associate	19404979, 26563374
Endometriosis	Inhibit	37081668
Fibromyalgia	Associate	34913882
Fibrosis	Associate	22531499
GATA2 Deficiency	Inhibit	27409423
Glioblastoma	Associate	32269065
Graft vs Host Disease	Inhibit	32849519
Hepatitis C	Associate	22457290
HIV Infections	Associate	28084312, 30364127, 34712231, 34762717
HIV Infections	Stimulate	30735686
Hypomagnesemia 5 Renal with Ocular Involvement	Associate	34367178
Infections	Associate	33717085
Inflammation	Associate	23980210, 26436997, 33861802, 35558085, 37491355, 39231385
Inflammatory Bowel Diseases	Associate	31582819, 40312552
Kotzot Richter syndrome	Associate	36655432
Leukemia	Associate	15536144, 34504191, 36655432
Leukemia Large Granular Lymphocytic	Associate	19580844, 20089172, 23667543
Leukemia Lymphocytic Chronic B Cell	Associate	30760844, 36655432
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	30705677
Leukemia Myeloid Acute	Associate	30639819, 31212079, 32802845, 34504191
Lung Diseases Interstitial	Associate	33413573
Lupus Erythematosus Systemic	Associate	20669283, 34373559, 40312552
Lupus Erythematosus Systemic	Stimulate	34367178
Lymphatic Metastasis	Inhibit	27626490
Lymphoma T Cell Cutaneous	Stimulate	28395975
Melanoma	Associate	25866972, 30046006
Multiple Myeloma	Stimulate	19098271
Multiple Myeloma	Associate	19748980, 23686482, 24913980, 25609078, 26269456, 27992381
Multiple Sclerosis	Associate	18971939, 18987646, 21765104, 27162345, 39231385
Myocarditis	Associate	38521068
Myositis	Associate	2168821, 37491355
Myositis Ossificans	Associate	28985649
Neoplasm Metastasis	Stimulate	35658892
Neoplasm Metastasis	Associate	36717657
Neoplasms	Associate	15136589, 19490613, 19748980, 23192659, 25609078, 26563374, 28084312, 28395975, 30255106, 30888046, 30908480, 31372841, 32802845, 33053327, 33299656 View all (6 more)
Neoplasms	Inhibit	24510590, 27626490, 31242243
Neoplasms Adipose Tissue	Associate	37869908
Neuroblastoma	Associate	27716850, 35967339
Neuromyelitis Optica	Stimulate	35587519
Oculocerebrorenal Syndrome	Associate	34367178
Ovarian Neoplasms	Associate	37876933
Pancreatic Neoplasms	Inhibit	25274283
Pancreatic Neoplasms	Associate	27626490
Pancreatitis	Associate	22403184
Peritoneal Neoplasms	Associate	31497016
Persistent Infection	Associate	26436997
Personality Disorders	Associate	24891767
Polyradiculoneuropathy Chronic Inflammatory Demyelinating	Associate	26436997
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	24658822
Prostatitis	Associate	25961317
Psoriasis	Associate	26613086
Pulmonary Fibrosis	Associate	21162102, 22531499
Sarcoma	Associate	23624801, 32082316
Scleroderma Diffuse	Associate	21162102
Scleroderma Systemic	Associate	21162102, 22531499, 37310903
Severe Acute Respiratory Syndrome	Associate	31916109
Sjogren's Syndrome	Associate	39263792
Small Cell Lung Carcinoma	Associate	33469055
Status Asthmaticus	Associate	16210593
Stomach Neoplasms	Inhibit	27409423
Stomach Neoplasms	Associate	30255106, 37056782
Thyroiditis Autoimmune	Associate	18971939
Vasculitis	Associate	19951419
Virus Diseases	Associate	28084312

CD226 (CD226 molecule)