Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10652
Gene name Gene Name - the full gene name approved by the HGNC.
YKT6 vesicular SNARE protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
YKT6
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p13
Summary Summary of gene provided in NCBI Entrez Gene.
This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021756 hsa-miR-132-3p Microarray 17612493
MIRT022550 hsa-miR-124-3p Microarray 18668037
MIRT023323 hsa-miR-122-5p Microarray 17612493
MIRT047824 hsa-miR-30d-5p CLASH 23622248
MIRT037749 hsa-miR-708-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane TAS
GO:0005484 Function SNAP receptor activity IDA 15215310
GO:0005737 Component Cytoplasm IDA 25468996
GO:0005739 Component Mitochondrion IDA
GO:0005768 Component Endosome IDA 15215310
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
606209 16959 ENSG00000106636
Protein
UniProt ID O15498
Protein name Synaptobrevin homolog YKT6 (EC 2.3.1.-)
Protein function Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GO
PDB 6J74 , 6J7F , 6J7X
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13774 Longin 44 122 Regulated-SNARE-like domain Domain
PF00957 Synaptobrevin 135 196 Synaptobrevin Family
Sequence
Sequence length 198
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  SNARE interactions in vesicular transport
Autophagy - animal
  COPII-mediated vesicle transport
COPI-mediated anterograde transport
Intra-Golgi traffic
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)
30054458
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 39375639
Adrenocortical Carcinoma Stimulate 37058019
Carcinoma Non Small Cell Lung Associate 27285987
Colonic Neoplasms Associate 37058019
Drug Related Side Effects and Adverse Reactions Associate 32188865
Lung Neoplasms Associate 27285987
Lymphatic Metastasis Stimulate 39375639
Metabolic Syndrome Associate 38201907
Neoplasm Metastasis Associate 34221701
Neoplasms Associate 27285987, 30010460, 34559989, 37058019