Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10613
Gene name Gene Name - the full gene name approved by the HGNC.	ER lipid raft associated 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ERLIN1
Synonyms (NCBI Gene) Gene synonyms aliases	C10orf69, Erlin-1, KE04, KEO4, SPFH1, SPG62
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q24.31
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which pro

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SNP ID	Visualize variation	Clinical significance	Consequence
rs876657413	G>A	Pathogenic	Stop gained, non coding transcript variant, coding sequence variant
rs876661322	C>A	Pathogenic	Coding sequence variant, intron variant, non coding transcript variant, 5 prime UTR variant, missense variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT025383	hsa-miR-34a-5p	Proteomics	21566225
MIRT025383	hsa-miR-34a-5p	Proteomics	21566225
MIRT025383	hsa-miR-34a-5p	Proteomics	21566225
MIRT025383	hsa-miR-34a-5p	Proteomics	21566225
MIRT025383	hsa-miR-34a-5p	Proteomics	21566225
MIRT028682	hsa-miR-30a-5p	Proteomics	18668040
MIRT051010	hsa-miR-17-5p	CLASH	23622248
MIRT047975	hsa-miR-30c-5p	CLASH	23622248
MIRT047667	hsa-miR-10a-5p	CLASH	23622248
MIRT047443	hsa-miR-10b-5p	CLASH	23622248
MIRT025383	hsa-miR-34a-5p	CLASH	23622248
MIRT025383	hsa-miR-34a-5p	CLASH	23622248
MIRT039885	hsa-miR-615-3p	CLASH	23622248
MIRT440711	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440711	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT028682	hsa-miR-30a-5p	HITS-CLIP	22473208
MIRT727747	hsa-miR-30b-5p	HITS-CLIP	22473208
MIRT047975	hsa-miR-30c-5p	HITS-CLIP	22473208
MIRT727746	hsa-miR-30d-5p	HITS-CLIP	22473208
MIRT727745	hsa-miR-30e-5p	HITS-CLIP	22473208
MIRT969239	hsa-miR-103a	CLIP-seq
MIRT969240	hsa-miR-106a	CLIP-seq
MIRT969241	hsa-miR-106b	CLIP-seq
MIRT969242	hsa-miR-107	CLIP-seq
MIRT969243	hsa-miR-1184	CLIP-seq
MIRT969244	hsa-miR-1205	CLIP-seq
MIRT969245	hsa-miR-1229	CLIP-seq
MIRT969246	hsa-miR-1234	CLIP-seq
MIRT969247	hsa-miR-1238	CLIP-seq
MIRT969248	hsa-miR-1254	CLIP-seq
MIRT969249	hsa-miR-1255a	CLIP-seq
MIRT969250	hsa-miR-1255b	CLIP-seq
MIRT969251	hsa-miR-1285	CLIP-seq
MIRT969252	hsa-miR-1286	CLIP-seq
MIRT969253	hsa-miR-1343	CLIP-seq
MIRT969254	hsa-miR-142-5p	CLIP-seq
MIRT969255	hsa-miR-145	CLIP-seq
MIRT969256	hsa-miR-148a	CLIP-seq
MIRT969257	hsa-miR-148b	CLIP-seq
MIRT969258	hsa-miR-152	CLIP-seq
MIRT969259	hsa-miR-17	CLIP-seq
MIRT969260	hsa-miR-1825	CLIP-seq
MIRT969261	hsa-miR-18a	CLIP-seq
MIRT969262	hsa-miR-18b	CLIP-seq
MIRT969263	hsa-miR-190	CLIP-seq
MIRT969264	hsa-miR-1909	CLIP-seq
MIRT969265	hsa-miR-190b	CLIP-seq
MIRT969266	hsa-miR-199a-5p	CLIP-seq
MIRT969267	hsa-miR-199b-5p	CLIP-seq
MIRT969268	hsa-miR-19a	CLIP-seq
MIRT969269	hsa-miR-19b	CLIP-seq
MIRT969270	hsa-miR-20a	CLIP-seq
MIRT969271	hsa-miR-20b	CLIP-seq
MIRT969272	hsa-miR-2110	CLIP-seq
MIRT969273	hsa-miR-2682	CLIP-seq
MIRT969274	hsa-miR-3074-5p	CLIP-seq
MIRT969275	hsa-miR-30a	CLIP-seq
MIRT969276	hsa-miR-30b	CLIP-seq
MIRT969277	hsa-miR-30c	CLIP-seq
MIRT969278	hsa-miR-30d	CLIP-seq
MIRT969279	hsa-miR-30e	CLIP-seq
MIRT969280	hsa-miR-3116	CLIP-seq
MIRT969281	hsa-miR-3124-3p	CLIP-seq
MIRT969282	hsa-miR-3143	CLIP-seq
MIRT969283	hsa-miR-3158-5p	CLIP-seq
MIRT969284	hsa-miR-3161	CLIP-seq
MIRT969285	hsa-miR-3187-5p	CLIP-seq
MIRT969286	hsa-miR-3191	CLIP-seq
MIRT969287	hsa-miR-3194-5p	CLIP-seq
MIRT969288	hsa-miR-34b	CLIP-seq
MIRT969289	hsa-miR-3591-5p	CLIP-seq
MIRT969290	hsa-miR-3609	CLIP-seq
MIRT969291	hsa-miR-3660	CLIP-seq
MIRT969292	hsa-miR-3675-5p	CLIP-seq
MIRT969293	hsa-miR-3679-3p	CLIP-seq
MIRT969294	hsa-miR-378g	CLIP-seq
MIRT969295	hsa-miR-3922-5p	CLIP-seq
MIRT969296	hsa-miR-421	CLIP-seq
MIRT969297	hsa-miR-4255	CLIP-seq
MIRT969298	hsa-miR-4257	CLIP-seq
MIRT969299	hsa-miR-4271	CLIP-seq
MIRT969300	hsa-miR-4272	CLIP-seq
MIRT969301	hsa-miR-4274	CLIP-seq
MIRT969302	hsa-miR-433	CLIP-seq
MIRT969303	hsa-miR-4418	CLIP-seq
MIRT969304	hsa-miR-4432	CLIP-seq
MIRT969305	hsa-miR-4434	CLIP-seq
MIRT969306	hsa-miR-4471	CLIP-seq
MIRT969307	hsa-miR-4486	CLIP-seq
MIRT969308	hsa-miR-4494	CLIP-seq
MIRT969309	hsa-miR-4495	CLIP-seq
MIRT969310	hsa-miR-4496	CLIP-seq
MIRT969311	hsa-miR-449c	CLIP-seq
MIRT969312	hsa-miR-4514	CLIP-seq
MIRT969313	hsa-miR-4516	CLIP-seq
MIRT969314	hsa-miR-4519	CLIP-seq
MIRT969315	hsa-miR-4526	CLIP-seq
MIRT969316	hsa-miR-4531	CLIP-seq
MIRT969317	hsa-miR-4532	CLIP-seq
MIRT969318	hsa-miR-4645-3p	CLIP-seq
MIRT969319	hsa-miR-4663	CLIP-seq
MIRT969320	hsa-miR-4667-5p	CLIP-seq
MIRT969321	hsa-miR-4692	CLIP-seq
MIRT969322	hsa-miR-4695-3p	CLIP-seq
MIRT969323	hsa-miR-4700-5p	CLIP-seq
MIRT969324	hsa-miR-4707-5p	CLIP-seq
MIRT969325	hsa-miR-4708-3p	CLIP-seq
MIRT969326	hsa-miR-4709-5p	CLIP-seq
MIRT969327	hsa-miR-4711-5p	CLIP-seq
MIRT969328	hsa-miR-4717-3p	CLIP-seq
MIRT969329	hsa-miR-4722-5p	CLIP-seq
MIRT969330	hsa-miR-4725-3p	CLIP-seq
MIRT969331	hsa-miR-4728-3p	CLIP-seq
MIRT969332	hsa-miR-4735-3p	CLIP-seq
MIRT969333	hsa-miR-4776-3p	CLIP-seq
MIRT969334	hsa-miR-4790-3p	CLIP-seq
MIRT969335	hsa-miR-4796-3p	CLIP-seq
MIRT969336	hsa-miR-4802-3p	CLIP-seq
MIRT969337	hsa-miR-4802-5p	CLIP-seq
MIRT969338	hsa-miR-486-3p	CLIP-seq
MIRT969339	hsa-miR-490-5p	CLIP-seq
MIRT969340	hsa-miR-499-5p	CLIP-seq
MIRT969341	hsa-miR-499a-5p	CLIP-seq
MIRT969342	hsa-miR-509-3-5p	CLIP-seq
MIRT969343	hsa-miR-509-5p	CLIP-seq
MIRT969344	hsa-miR-519d	CLIP-seq
MIRT969345	hsa-miR-543	CLIP-seq
MIRT969346	hsa-miR-548ah	CLIP-seq
MIRT969347	hsa-miR-570	CLIP-seq
MIRT969348	hsa-miR-612	CLIP-seq
MIRT969349	hsa-miR-628-5p	CLIP-seq
MIRT969350	hsa-miR-640	CLIP-seq
MIRT969351	hsa-miR-93	CLIP-seq
MIRT1548424	hsa-miR-4759	CLIP-seq
MIRT969239	hsa-miR-103a	CLIP-seq
MIRT969240	hsa-miR-106a	CLIP-seq
MIRT969241	hsa-miR-106b	CLIP-seq
MIRT969242	hsa-miR-107	CLIP-seq
MIRT969243	hsa-miR-1184	CLIP-seq
MIRT969244	hsa-miR-1205	CLIP-seq
MIRT1987231	hsa-miR-1207-3p	CLIP-seq
MIRT969247	hsa-miR-1238	CLIP-seq
MIRT1987232	hsa-miR-136	CLIP-seq
MIRT969254	hsa-miR-142-5p	CLIP-seq
MIRT969255	hsa-miR-145	CLIP-seq
MIRT969256	hsa-miR-148a	CLIP-seq
MIRT969257	hsa-miR-148b	CLIP-seq
MIRT969258	hsa-miR-152	CLIP-seq
MIRT969259	hsa-miR-17	CLIP-seq
MIRT969260	hsa-miR-1825	CLIP-seq
MIRT969266	hsa-miR-199a-5p	CLIP-seq
MIRT969267	hsa-miR-199b-5p	CLIP-seq
MIRT969270	hsa-miR-20a	CLIP-seq
MIRT969271	hsa-miR-20b	CLIP-seq
MIRT1987233	hsa-miR-2277-3p	CLIP-seq
MIRT969273	hsa-miR-2682	CLIP-seq
MIRT969281	hsa-miR-3124-3p	CLIP-seq
MIRT969282	hsa-miR-3143	CLIP-seq
MIRT969283	hsa-miR-3158-5p	CLIP-seq
MIRT1987234	hsa-miR-339-5p	CLIP-seq
MIRT1987235	hsa-miR-3545-5p	CLIP-seq
MIRT969289	hsa-miR-3591-5p	CLIP-seq
MIRT969290	hsa-miR-3609	CLIP-seq
MIRT969291	hsa-miR-3660	CLIP-seq
MIRT1987236	hsa-miR-3663-3p	CLIP-seq
MIRT1987237	hsa-miR-3692	CLIP-seq
MIRT1987238	hsa-miR-374a	CLIP-seq
MIRT1987239	hsa-miR-374b	CLIP-seq
MIRT969294	hsa-miR-378g	CLIP-seq
MIRT969297	hsa-miR-4255	CLIP-seq
MIRT969298	hsa-miR-4257	CLIP-seq
MIRT969301	hsa-miR-4274	CLIP-seq
MIRT1987240	hsa-miR-4281	CLIP-seq
MIRT969305	hsa-miR-4434	CLIP-seq
MIRT969308	hsa-miR-4494	CLIP-seq
MIRT969310	hsa-miR-4496	CLIP-seq
MIRT969311	hsa-miR-449c	CLIP-seq
MIRT1987241	hsa-miR-4503	CLIP-seq
MIRT969312	hsa-miR-4514	CLIP-seq
MIRT969313	hsa-miR-4516	CLIP-seq
MIRT969314	hsa-miR-4519	CLIP-seq
MIRT969315	hsa-miR-4526	CLIP-seq
MIRT969316	hsa-miR-4531	CLIP-seq
MIRT1987242	hsa-miR-4650-5p	CLIP-seq
MIRT1987243	hsa-miR-4691-5p	CLIP-seq
MIRT969321	hsa-miR-4692	CLIP-seq
MIRT969327	hsa-miR-4711-5p	CLIP-seq
MIRT1548424	hsa-miR-4759	CLIP-seq
MIRT1987244	hsa-miR-4766-5p	CLIP-seq
MIRT1987245	hsa-miR-4777-5p	CLIP-seq
MIRT1987246	hsa-miR-4795-5p	CLIP-seq
MIRT969335	hsa-miR-4796-3p	CLIP-seq
MIRT969341	hsa-miR-499a-5p	CLIP-seq
MIRT1987247	hsa-miR-515-5p	CLIP-seq
MIRT1987248	hsa-miR-518d-5p	CLIP-seq
MIRT1987249	hsa-miR-519b-5p	CLIP-seq
MIRT1987250	hsa-miR-519c-5p	CLIP-seq
MIRT969344	hsa-miR-519d	CLIP-seq
MIRT1987251	hsa-miR-520c-5p	CLIP-seq
MIRT1987252	hsa-miR-526a	CLIP-seq
MIRT969345	hsa-miR-543	CLIP-seq
MIRT969346	hsa-miR-548ah	CLIP-seq
MIRT969347	hsa-miR-570	CLIP-seq
MIRT969351	hsa-miR-93	CLIP-seq
MIRT1987253	hsa-miR-944	CLIP-seq
MIRT969239	hsa-miR-103a	CLIP-seq
MIRT969242	hsa-miR-107	CLIP-seq
MIRT969244	hsa-miR-1205	CLIP-seq
MIRT1987231	hsa-miR-1207-3p	CLIP-seq
MIRT2221724	hsa-miR-1243	CLIP-seq
MIRT2221725	hsa-miR-1245b-3p	CLIP-seq
MIRT969249	hsa-miR-1255a	CLIP-seq
MIRT969250	hsa-miR-1255b	CLIP-seq
MIRT969253	hsa-miR-1343	CLIP-seq
MIRT2221726	hsa-miR-3065-5p	CLIP-seq
MIRT2221727	hsa-miR-3199	CLIP-seq
MIRT969291	hsa-miR-3660	CLIP-seq
MIRT2221728	hsa-miR-4493	CLIP-seq
MIRT2221729	hsa-miR-4505	CLIP-seq
MIRT2221730	hsa-miR-4515	CLIP-seq
MIRT969315	hsa-miR-4526	CLIP-seq
MIRT969329	hsa-miR-4722-5p	CLIP-seq
MIRT2221731	hsa-miR-4733-5p	CLIP-seq
MIRT1548424	hsa-miR-4759	CLIP-seq
MIRT2221732	hsa-miR-4768-3p	CLIP-seq
MIRT1987246	hsa-miR-4795-5p	CLIP-seq
MIRT2221733	hsa-miR-495	CLIP-seq
MIRT2221734	hsa-miR-548g	CLIP-seq
MIRT969240	hsa-miR-106a	CLIP-seq
MIRT969241	hsa-miR-106b	CLIP-seq
MIRT969254	hsa-miR-142-5p	CLIP-seq
MIRT969259	hsa-miR-17	CLIP-seq
MIRT969270	hsa-miR-20a	CLIP-seq
MIRT969271	hsa-miR-20b	CLIP-seq
MIRT969281	hsa-miR-3124-3p	CLIP-seq
MIRT969290	hsa-miR-3609	CLIP-seq
MIRT969291	hsa-miR-3660	CLIP-seq
MIRT2387531	hsa-miR-3672	CLIP-seq
MIRT969294	hsa-miR-378g	CLIP-seq
MIRT2387532	hsa-miR-4499	CLIP-seq
MIRT2387533	hsa-miR-4513	CLIP-seq
MIRT969315	hsa-miR-4526	CLIP-seq
MIRT969335	hsa-miR-4796-3p	CLIP-seq
MIRT969344	hsa-miR-519d	CLIP-seq
MIRT969346	hsa-miR-548ah	CLIP-seq
MIRT969351	hsa-miR-93	CLIP-seq
MIRT969240	hsa-miR-106a	CLIP-seq
MIRT969241	hsa-miR-106b	CLIP-seq
MIRT2525365	hsa-miR-1267	CLIP-seq
MIRT2525366	hsa-miR-129-5p	CLIP-seq
MIRT969254	hsa-miR-142-5p	CLIP-seq
MIRT969259	hsa-miR-17	CLIP-seq
MIRT2525367	hsa-miR-1972	CLIP-seq
MIRT2525368	hsa-miR-208a	CLIP-seq
MIRT2525369	hsa-miR-208b	CLIP-seq
MIRT969270	hsa-miR-20a	CLIP-seq
MIRT969271	hsa-miR-20b	CLIP-seq
MIRT1987233	hsa-miR-2277-3p	CLIP-seq
MIRT2525370	hsa-miR-27a	CLIP-seq
MIRT2525371	hsa-miR-27b	CLIP-seq
MIRT2525372	hsa-miR-298	CLIP-seq
MIRT2525373	hsa-miR-302a	CLIP-seq
MIRT2525374	hsa-miR-302b	CLIP-seq
MIRT2525375	hsa-miR-302c	CLIP-seq
MIRT2525376	hsa-miR-302d	CLIP-seq
MIRT2525377	hsa-miR-302e	CLIP-seq
MIRT2525378	hsa-miR-3064-3p	CLIP-seq
MIRT969281	hsa-miR-3124-3p	CLIP-seq
MIRT2525379	hsa-miR-3148	CLIP-seq
MIRT1987234	hsa-miR-339-5p	CLIP-seq
MIRT1987235	hsa-miR-3545-5p	CLIP-seq
MIRT969290	hsa-miR-3609	CLIP-seq
MIRT2525380	hsa-miR-3647-3p	CLIP-seq
MIRT2525381	hsa-miR-3658	CLIP-seq
MIRT969291	hsa-miR-3660	CLIP-seq
MIRT2525382	hsa-miR-3664-5p	CLIP-seq
MIRT2525383	hsa-miR-3688-3p	CLIP-seq
MIRT2525384	hsa-miR-372	CLIP-seq
MIRT2525385	hsa-miR-373	CLIP-seq
MIRT2525386	hsa-miR-377	CLIP-seq
MIRT969294	hsa-miR-378g	CLIP-seq
MIRT969296	hsa-miR-421	CLIP-seq
MIRT1987240	hsa-miR-4281	CLIP-seq
MIRT2525387	hsa-miR-4326	CLIP-seq
MIRT2525388	hsa-miR-4420	CLIP-seq
MIRT969304	hsa-miR-4432	CLIP-seq
MIRT2525389	hsa-miR-4446-5p	CLIP-seq
MIRT1987241	hsa-miR-4503	CLIP-seq
MIRT969315	hsa-miR-4526	CLIP-seq
MIRT2525390	hsa-miR-4643	CLIP-seq
MIRT1987242	hsa-miR-4650-5p	CLIP-seq
MIRT2525391	hsa-miR-4690-3p	CLIP-seq
MIRT2525392	hsa-miR-4709-3p	CLIP-seq
MIRT969328	hsa-miR-4717-3p	CLIP-seq
MIRT2525393	hsa-miR-4731-3p	CLIP-seq
MIRT2525394	hsa-miR-4755-5p	CLIP-seq
MIRT2525395	hsa-miR-4764-3p	CLIP-seq
MIRT1987244	hsa-miR-4766-5p	CLIP-seq
MIRT1987245	hsa-miR-4777-5p	CLIP-seq
MIRT1987246	hsa-miR-4795-5p	CLIP-seq
MIRT969335	hsa-miR-4796-3p	CLIP-seq
MIRT2525396	hsa-miR-4801	CLIP-seq
MIRT969339	hsa-miR-490-5p	CLIP-seq
MIRT969340	hsa-miR-499-5p	CLIP-seq
MIRT2525397	hsa-miR-510	CLIP-seq
MIRT2525398	hsa-miR-511	CLIP-seq
MIRT2525399	hsa-miR-513a-5p	CLIP-seq
MIRT1987248	hsa-miR-518d-5p	CLIP-seq
MIRT1987249	hsa-miR-519b-5p	CLIP-seq
MIRT1987250	hsa-miR-519c-5p	CLIP-seq
MIRT969344	hsa-miR-519d	CLIP-seq
MIRT2525400	hsa-miR-520a-3p	CLIP-seq
MIRT2525401	hsa-miR-520b	CLIP-seq
MIRT2525402	hsa-miR-520c-3p	CLIP-seq
MIRT1987251	hsa-miR-520c-5p	CLIP-seq
MIRT2525403	hsa-miR-520d-3p	CLIP-seq
MIRT2525404	hsa-miR-520e	CLIP-seq
MIRT2525405	hsa-miR-520f	CLIP-seq
MIRT1987252	hsa-miR-526a	CLIP-seq
MIRT969346	hsa-miR-548ah	CLIP-seq
MIRT2525406	hsa-miR-618	CLIP-seq
MIRT2525407	hsa-miR-653	CLIP-seq
MIRT2525408	hsa-miR-670	CLIP-seq
MIRT969351	hsa-miR-93	CLIP-seq
MIRT969240	hsa-miR-106a	CLIP-seq
MIRT969241	hsa-miR-106b	CLIP-seq
MIRT2680264	hsa-miR-1178	CLIP-seq
MIRT1987231	hsa-miR-1207-3p	CLIP-seq
MIRT2525365	hsa-miR-1267	CLIP-seq
MIRT2680265	hsa-miR-1281	CLIP-seq
MIRT2680266	hsa-miR-1290	CLIP-seq
MIRT2525366	hsa-miR-129-5p	CLIP-seq
MIRT969253	hsa-miR-1343	CLIP-seq
MIRT969254	hsa-miR-142-5p	CLIP-seq
MIRT969259	hsa-miR-17	CLIP-seq
MIRT2525367	hsa-miR-1972	CLIP-seq
MIRT2680267	hsa-miR-1976	CLIP-seq
MIRT2525368	hsa-miR-208a	CLIP-seq
MIRT2525369	hsa-miR-208b	CLIP-seq
MIRT969270	hsa-miR-20a	CLIP-seq
MIRT969271	hsa-miR-20b	CLIP-seq
MIRT1987233	hsa-miR-2277-3p	CLIP-seq
MIRT2525370	hsa-miR-27a	CLIP-seq
MIRT2525371	hsa-miR-27b	CLIP-seq
MIRT2525372	hsa-miR-298	CLIP-seq
MIRT2525373	hsa-miR-302a	CLIP-seq
MIRT2525374	hsa-miR-302b	CLIP-seq
MIRT2525375	hsa-miR-302c	CLIP-seq
MIRT2525376	hsa-miR-302d	CLIP-seq
MIRT2525377	hsa-miR-302e	CLIP-seq
MIRT2525378	hsa-miR-3064-3p	CLIP-seq
MIRT2680268	hsa-miR-3064-5p	CLIP-seq
MIRT969281	hsa-miR-3124-3p	CLIP-seq
MIRT2680269	hsa-miR-3135b	CLIP-seq
MIRT2680270	hsa-miR-3140-3p	CLIP-seq
MIRT2525379	hsa-miR-3148	CLIP-seq
MIRT2680271	hsa-miR-3167	CLIP-seq
MIRT1987234	hsa-miR-339-5p	CLIP-seq
MIRT1987235	hsa-miR-3545-5p	CLIP-seq
MIRT969290	hsa-miR-3609	CLIP-seq
MIRT2525380	hsa-miR-3647-3p	CLIP-seq
MIRT2525381	hsa-miR-3658	CLIP-seq
MIRT969291	hsa-miR-3660	CLIP-seq
MIRT2525382	hsa-miR-3664-5p	CLIP-seq
MIRT2525383	hsa-miR-3688-3p	CLIP-seq
MIRT2525384	hsa-miR-372	CLIP-seq
MIRT2525385	hsa-miR-373	CLIP-seq
MIRT2525386	hsa-miR-377	CLIP-seq
MIRT969294	hsa-miR-378g	CLIP-seq
MIRT2680272	hsa-miR-3918	CLIP-seq
MIRT969296	hsa-miR-421	CLIP-seq
MIRT2680273	hsa-miR-4260	CLIP-seq
MIRT1987240	hsa-miR-4281	CLIP-seq
MIRT2525387	hsa-miR-4326	CLIP-seq
MIRT2525388	hsa-miR-4420	CLIP-seq
MIRT969304	hsa-miR-4432	CLIP-seq
MIRT969305	hsa-miR-4434	CLIP-seq
MIRT2525389	hsa-miR-4446-5p	CLIP-seq
MIRT1987241	hsa-miR-4503	CLIP-seq
MIRT969313	hsa-miR-4516	CLIP-seq
MIRT969315	hsa-miR-4526	CLIP-seq
MIRT2680274	hsa-miR-4529-5p	CLIP-seq
MIRT969316	hsa-miR-4531	CLIP-seq
MIRT2525390	hsa-miR-4643	CLIP-seq
MIRT1987242	hsa-miR-4650-5p	CLIP-seq
MIRT2680275	hsa-miR-4685-5p	CLIP-seq
MIRT2525391	hsa-miR-4690-3p	CLIP-seq
MIRT969322	hsa-miR-4695-3p	CLIP-seq
MIRT2680276	hsa-miR-4697-3p	CLIP-seq
MIRT969328	hsa-miR-4717-3p	CLIP-seq
MIRT2525393	hsa-miR-4731-3p	CLIP-seq
MIRT2525394	hsa-miR-4755-5p	CLIP-seq
MIRT2525395	hsa-miR-4764-3p	CLIP-seq
MIRT1987244	hsa-miR-4766-5p	CLIP-seq
MIRT1987245	hsa-miR-4777-5p	CLIP-seq
MIRT1987246	hsa-miR-4795-5p	CLIP-seq
MIRT969335	hsa-miR-4796-3p	CLIP-seq
MIRT2525396	hsa-miR-4801	CLIP-seq
MIRT969338	hsa-miR-486-3p	CLIP-seq
MIRT969339	hsa-miR-490-5p	CLIP-seq
MIRT969340	hsa-miR-499-5p	CLIP-seq
MIRT2525397	hsa-miR-510	CLIP-seq
MIRT2525398	hsa-miR-511	CLIP-seq
MIRT2525399	hsa-miR-513a-5p	CLIP-seq
MIRT1987248	hsa-miR-518d-5p	CLIP-seq
MIRT1987249	hsa-miR-519b-5p	CLIP-seq
MIRT1987250	hsa-miR-519c-5p	CLIP-seq
MIRT969344	hsa-miR-519d	CLIP-seq
MIRT2525400	hsa-miR-520a-3p	CLIP-seq
MIRT2525401	hsa-miR-520b	CLIP-seq
MIRT2525402	hsa-miR-520c-3p	CLIP-seq
MIRT1987251	hsa-miR-520c-5p	CLIP-seq
MIRT2525403	hsa-miR-520d-3p	CLIP-seq
MIRT2525404	hsa-miR-520e	CLIP-seq
MIRT2525405	hsa-miR-520f	CLIP-seq
MIRT1987252	hsa-miR-526a	CLIP-seq
MIRT969346	hsa-miR-548ah	CLIP-seq
MIRT2680277	hsa-miR-604	CLIP-seq
MIRT2525406	hsa-miR-618	CLIP-seq
MIRT2680278	hsa-miR-637	CLIP-seq
MIRT2680279	hsa-miR-647	CLIP-seq
MIRT2525407	hsa-miR-653	CLIP-seq
MIRT2525408	hsa-miR-670	CLIP-seq
MIRT2680280	hsa-miR-876-5p	CLIP-seq
MIRT2680281	hsa-miR-890	CLIP-seq
MIRT2680282	hsa-miR-892b	CLIP-seq
MIRT969351	hsa-miR-93	CLIP-seq

Show/Hide all(28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19240031, 21343306, 22119785, 25416956, 28514442, 30021884, 32296183, 33961781
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	16835267, 19240031
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0008202	Process	Steroid metabolic process	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0015485	Function	Cholesterol binding	IBA
GO:0015485	Function	Cholesterol binding	IDA	24217618
GO:0016020	Component	Membrane	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0032933	Process	SREBP signaling pathway	IBA
GO:0032933	Process	SREBP signaling pathway	IEA
GO:0032933	Process	SREBP signaling pathway	IMP	24217618
GO:0032991	Component	Protein-containing complex	IDA	18468998
GO:0032991	Component	Protein-containing complex	IEA
GO:0036503	Process	ERAD pathway	IDA	19240031
GO:0036503	Process	ERAD pathway	IEA
GO:0045121	Component	Membrane raft	NAS	34572057
GO:0045540	Process	Regulation of cholesterol biosynthetic process	IDA	24217618
GO:0045541	Process	Negative regulation of cholesterol biosynthetic process	IEA
GO:0045541	Process	Negative regulation of cholesterol biosynthetic process	IMP	24217618
GO:0045717	Process	Negative regulation of fatty acid biosynthetic process	IEA
GO:0045717	Process	Negative regulation of fatty acid biosynthetic process	IMP	24217618

MIM	HGNC	e!Ensembl
611604	16947	ENSG00000107566

Protein

UniProt ID

O75477

Protein name

Erlin-1 (Endoplasmic reticulum lipid raft-associated protein 1) (Protein KE04) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1) (SPFH domain-containing protein 1)

Protein function

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP s

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01145	Band_7	26 → 216	SPFH domain / Band 7 family	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine. {ECO:0000269|PubMed:11118313}.

Sequence

MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITT
FRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFN
KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA
IRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET
EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG
SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG

Sequence length

348

Interactions

View interactions

	Reactome
			ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis

Show/Hide Causal Diseases (2)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Amyotrophic Lateral Sclerosis	juvenile amyotrophic lateral sclerosis	rs1844420892	N/A
Hereditary spastic paraplegia	Hereditary spastic paraplegia 62	rs876661322	N/A

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes, Type 2 diabetes or schizophrenia (pleiotropy)	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Amyotrophic Lateral Sclerosis	Associate	29453415
Colorectal Neoplasms	Associate	35412433
Coronary Artery Disease	Associate	28120895
Hyperbilirubinemia	Associate	29453415
Motor Neuron Disease	Associate	29453415
Neoplasms	Associate	29596435
Neoplasms	Stimulate	35412433
Neurodegenerative Diseases	Associate	31874412
Non alcoholic Fatty Liver Disease	Associate	24785259, 32841307, 34558842
Pancreatic Neoplasms	Associate	29596435
Spastic Paraplegia Hereditary	Associate	29453415

ERLIN1 (ER lipid raft associated 1)