Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10565
Gene name Gene Name - the full gene name approved by the HGNC.	ARF guanine nucleotide exchange factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ARFGEF1
Synonyms (NCBI Gene) Gene synonyms aliases	ARFGEP1, BIG1, DEDISB, P200
Disease Acronyms (UniProt) Disease acronyms from UniProt database	DEDISB
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8q13.2
Summary Summary of gene provided in NCBI Entrez Gene.	ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may b

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miRTarBase ID	miRNA	Experiments	Reference
MIRT024514	hsa-miR-215-5p	Microarray	19074876
MIRT026910	hsa-miR-192-5p	Microarray	19074876
MIRT047646	hsa-miR-10a-5p	CLASH	23622248
MIRT047437	hsa-miR-10b-5p	CLASH	23622248
MIRT038638	hsa-miR-125a-3p	CLASH	23622248
MIRT037025	hsa-miR-877-3p	CLASH	23622248
MIRT442539	hsa-miR-424-3p	PAR-CLIP	22100165
MIRT442538	hsa-miR-1228-3p	PAR-CLIP	22100165
MIRT442537	hsa-miR-4722-3p	PAR-CLIP	22100165
MIRT442536	hsa-miR-6727-3p	PAR-CLIP	22100165
MIRT442535	hsa-miR-3692-3p	PAR-CLIP	22100165
MIRT402567	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT402568	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT442539	hsa-miR-424-3p	PAR-CLIP	22100165
MIRT442538	hsa-miR-1228-3p	PAR-CLIP	22100165
MIRT442537	hsa-miR-4722-3p	PAR-CLIP	22100165
MIRT442536	hsa-miR-6727-3p	PAR-CLIP	22100165
MIRT442535	hsa-miR-3692-3p	PAR-CLIP	22100165
MIRT792904	hsa-miR-1208	CLIP-seq
MIRT792905	hsa-miR-1228	CLIP-seq
MIRT792906	hsa-miR-128	CLIP-seq
MIRT792907	hsa-miR-1285	CLIP-seq
MIRT792908	hsa-miR-1297	CLIP-seq
MIRT792909	hsa-miR-130a	CLIP-seq
MIRT792910	hsa-miR-130b	CLIP-seq
MIRT792911	hsa-miR-133a	CLIP-seq
MIRT792912	hsa-miR-133b	CLIP-seq
MIRT792913	hsa-miR-144	CLIP-seq
MIRT792914	hsa-miR-2277-3p	CLIP-seq
MIRT792915	hsa-miR-26a	CLIP-seq
MIRT792916	hsa-miR-26b	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT792919	hsa-miR-301a	CLIP-seq
MIRT792920	hsa-miR-301b	CLIP-seq
MIRT792921	hsa-miR-3117-5p	CLIP-seq
MIRT792922	hsa-miR-3160-3p	CLIP-seq
MIRT792923	hsa-miR-3160-5p	CLIP-seq
MIRT792924	hsa-miR-3187-5p	CLIP-seq
MIRT792925	hsa-miR-3190	CLIP-seq
MIRT792926	hsa-miR-3591-5p	CLIP-seq
MIRT792927	hsa-miR-3613-5p	CLIP-seq
MIRT792928	hsa-miR-3662	CLIP-seq
MIRT792929	hsa-miR-3666	CLIP-seq
MIRT792930	hsa-miR-3692	CLIP-seq
MIRT792931	hsa-miR-376c	CLIP-seq
MIRT792932	hsa-miR-378g	CLIP-seq
MIRT792933	hsa-miR-382	CLIP-seq
MIRT792934	hsa-miR-3919	CLIP-seq
MIRT792935	hsa-miR-3945	CLIP-seq
MIRT792936	hsa-miR-4253	CLIP-seq
MIRT792937	hsa-miR-4295	CLIP-seq
MIRT792938	hsa-miR-4314	CLIP-seq
MIRT792939	hsa-miR-4320	CLIP-seq
MIRT792940	hsa-miR-4438	CLIP-seq
MIRT792941	hsa-miR-4465	CLIP-seq
MIRT792942	hsa-miR-4473	CLIP-seq
MIRT792943	hsa-miR-4486	CLIP-seq
MIRT792944	hsa-miR-4487	CLIP-seq
MIRT792945	hsa-miR-450b-5p	CLIP-seq
MIRT792946	hsa-miR-452	CLIP-seq
MIRT792947	hsa-miR-4533	CLIP-seq
MIRT792948	hsa-miR-454	CLIP-seq
MIRT792949	hsa-miR-4671-3p	CLIP-seq
MIRT792950	hsa-miR-4676-3p	CLIP-seq
MIRT792951	hsa-miR-4747-5p	CLIP-seq
MIRT792952	hsa-miR-4782-5p	CLIP-seq
MIRT792953	hsa-miR-507	CLIP-seq
MIRT792954	hsa-miR-5096	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT792956	hsa-miR-514	CLIP-seq
MIRT792957	hsa-miR-514b-3p	CLIP-seq
MIRT792958	hsa-miR-520a-5p	CLIP-seq
MIRT792959	hsa-miR-525-5p	CLIP-seq
MIRT792960	hsa-miR-539	CLIP-seq
MIRT792961	hsa-miR-544	CLIP-seq
MIRT792962	hsa-miR-555	CLIP-seq
MIRT792963	hsa-miR-556-5p	CLIP-seq
MIRT792964	hsa-miR-557	CLIP-seq
MIRT792965	hsa-miR-558	CLIP-seq
MIRT792966	hsa-miR-579	CLIP-seq
MIRT792967	hsa-miR-612	CLIP-seq
MIRT792968	hsa-miR-664	CLIP-seq
MIRT792969	hsa-miR-7	CLIP-seq
MIRT792970	hsa-miR-767-3p	CLIP-seq
MIRT792906	hsa-miR-128	CLIP-seq
MIRT792913	hsa-miR-144	CLIP-seq
MIRT1545468	hsa-miR-145	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT1545469	hsa-miR-3150a-5p	CLIP-seq
MIRT1545470	hsa-miR-3150b-5p	CLIP-seq
MIRT1545471	hsa-miR-3180-5p	CLIP-seq
MIRT1545472	hsa-miR-4712-5p	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT1545473	hsa-miR-770-5p	CLIP-seq
MIRT1933982	hsa-miR-122	CLIP-seq
MIRT1933983	hsa-miR-1226	CLIP-seq
MIRT1933984	hsa-miR-197	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT1933985	hsa-miR-3199	CLIP-seq
MIRT792927	hsa-miR-3613-5p	CLIP-seq
MIRT1933986	hsa-miR-3616-5p	CLIP-seq
MIRT1933987	hsa-miR-3647-5p	CLIP-seq
MIRT1933988	hsa-miR-3659	CLIP-seq
MIRT1933989	hsa-miR-371b-5p	CLIP-seq
MIRT792931	hsa-miR-376c	CLIP-seq
MIRT792933	hsa-miR-382	CLIP-seq
MIRT1933990	hsa-miR-4432	CLIP-seq
MIRT1933991	hsa-miR-4446-5p	CLIP-seq
MIRT1933992	hsa-miR-4475	CLIP-seq
MIRT1933993	hsa-miR-4515	CLIP-seq
MIRT1933994	hsa-miR-4668-3p	CLIP-seq
MIRT1933995	hsa-miR-4684-3p	CLIP-seq
MIRT1933996	hsa-miR-4698	CLIP-seq
MIRT1933997	hsa-miR-4755-5p	CLIP-seq
MIRT1933998	hsa-miR-499-5p	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT1933999	hsa-miR-573	CLIP-seq
MIRT1934000	hsa-miR-634	CLIP-seq
MIRT1934001	hsa-miR-653	CLIP-seq
MIRT792904	hsa-miR-1208	CLIP-seq
MIRT1933982	hsa-miR-122	CLIP-seq
MIRT1933983	hsa-miR-1226	CLIP-seq
MIRT792905	hsa-miR-1228	CLIP-seq
MIRT2173813	hsa-miR-1276	CLIP-seq
MIRT792906	hsa-miR-128	CLIP-seq
MIRT792908	hsa-miR-1297	CLIP-seq
MIRT2173814	hsa-miR-1324	CLIP-seq
MIRT792911	hsa-miR-133a	CLIP-seq
MIRT792912	hsa-miR-133b	CLIP-seq
MIRT792913	hsa-miR-144	CLIP-seq
MIRT1545468	hsa-miR-145	CLIP-seq
MIRT2173815	hsa-miR-19a	CLIP-seq
MIRT2173816	hsa-miR-19b	CLIP-seq
MIRT2173817	hsa-miR-2053	CLIP-seq
MIRT792914	hsa-miR-2277-3p	CLIP-seq
MIRT2173818	hsa-miR-2278	CLIP-seq
MIRT2173819	hsa-miR-24	CLIP-seq
MIRT2173820	hsa-miR-2467-3p	CLIP-seq
MIRT792915	hsa-miR-26a	CLIP-seq
MIRT792916	hsa-miR-26b	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT2173821	hsa-miR-3074-5p	CLIP-seq
MIRT792921	hsa-miR-3117-5p	CLIP-seq
MIRT2173822	hsa-miR-3119	CLIP-seq
MIRT2173823	hsa-miR-3120-3p	CLIP-seq
MIRT1545469	hsa-miR-3150a-5p	CLIP-seq
MIRT1545470	hsa-miR-3150b-5p	CLIP-seq
MIRT792923	hsa-miR-3160-5p	CLIP-seq
MIRT1545471	hsa-miR-3180-5p	CLIP-seq
MIRT792925	hsa-miR-3190	CLIP-seq
MIRT1933985	hsa-miR-3199	CLIP-seq
MIRT2173824	hsa-miR-3655	CLIP-seq
MIRT1933988	hsa-miR-3659	CLIP-seq
MIRT792928	hsa-miR-3662	CLIP-seq
MIRT2173825	hsa-miR-3686	CLIP-seq
MIRT792930	hsa-miR-3692	CLIP-seq
MIRT2173826	hsa-miR-374c	CLIP-seq
MIRT792931	hsa-miR-376c	CLIP-seq
MIRT792933	hsa-miR-382	CLIP-seq
MIRT792934	hsa-miR-3919	CLIP-seq
MIRT2173827	hsa-miR-3920	CLIP-seq
MIRT2173828	hsa-miR-410	CLIP-seq
MIRT2173829	hsa-miR-4263	CLIP-seq
MIRT2173830	hsa-miR-4282	CLIP-seq
MIRT2173831	hsa-miR-4283	CLIP-seq
MIRT2173832	hsa-miR-4284	CLIP-seq
MIRT2173833	hsa-miR-4293	CLIP-seq
MIRT2173834	hsa-miR-4311	CLIP-seq
MIRT792939	hsa-miR-4320	CLIP-seq
MIRT2173835	hsa-miR-4330	CLIP-seq
MIRT1933990	hsa-miR-4432	CLIP-seq
MIRT792940	hsa-miR-4438	CLIP-seq
MIRT792941	hsa-miR-4465	CLIP-seq
MIRT2173836	hsa-miR-4468	CLIP-seq
MIRT1933992	hsa-miR-4475	CLIP-seq
MIRT2173837	hsa-miR-4489	CLIP-seq
MIRT2173838	hsa-miR-4495	CLIP-seq
MIRT2173839	hsa-miR-4496	CLIP-seq
MIRT792945	hsa-miR-450b-5p	CLIP-seq
MIRT1933993	hsa-miR-4515	CLIP-seq
MIRT792946	hsa-miR-452	CLIP-seq
MIRT2173840	hsa-miR-4639-5p	CLIP-seq
MIRT2173841	hsa-miR-4658	CLIP-seq
MIRT1933994	hsa-miR-4668-3p	CLIP-seq
MIRT792950	hsa-miR-4676-3p	CLIP-seq
MIRT1933995	hsa-miR-4684-3p	CLIP-seq
MIRT1545472	hsa-miR-4712-5p	CLIP-seq
MIRT2173842	hsa-miR-4738-5p	CLIP-seq
MIRT2173843	hsa-miR-4778-5p	CLIP-seq
MIRT792952	hsa-miR-4782-5p	CLIP-seq
MIRT1933998	hsa-miR-499-5p	CLIP-seq
MIRT792953	hsa-miR-507	CLIP-seq
MIRT792954	hsa-miR-5096	CLIP-seq
MIRT2173844	hsa-miR-511	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT792958	hsa-miR-520a-5p	CLIP-seq
MIRT792959	hsa-miR-525-5p	CLIP-seq
MIRT792960	hsa-miR-539	CLIP-seq
MIRT792961	hsa-miR-544	CLIP-seq
MIRT2173845	hsa-miR-548c-3p	CLIP-seq
MIRT2173846	hsa-miR-548n	CLIP-seq
MIRT2173847	hsa-miR-548t	CLIP-seq
MIRT792962	hsa-miR-555	CLIP-seq
MIRT792964	hsa-miR-557	CLIP-seq
MIRT2173848	hsa-miR-569	CLIP-seq
MIRT2173849	hsa-miR-574-5p	CLIP-seq
MIRT792966	hsa-miR-579	CLIP-seq
MIRT2173850	hsa-miR-583	CLIP-seq
MIRT2173851	hsa-miR-596	CLIP-seq
MIRT1934000	hsa-miR-634	CLIP-seq
MIRT2173852	hsa-miR-648	CLIP-seq
MIRT2173853	hsa-miR-655	CLIP-seq
MIRT2173854	hsa-miR-656	CLIP-seq
MIRT792968	hsa-miR-664	CLIP-seq
MIRT792969	hsa-miR-7	CLIP-seq
MIRT2173855	hsa-miR-766	CLIP-seq
MIRT792970	hsa-miR-767-3p	CLIP-seq
MIRT1545473	hsa-miR-770-5p	CLIP-seq
MIRT2173856	hsa-miR-889	CLIP-seq
MIRT792906	hsa-miR-128	CLIP-seq
MIRT792913	hsa-miR-144	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT792904	hsa-miR-1208	CLIP-seq
MIRT1933982	hsa-miR-122	CLIP-seq
MIRT1933983	hsa-miR-1226	CLIP-seq
MIRT2173813	hsa-miR-1276	CLIP-seq
MIRT792906	hsa-miR-128	CLIP-seq
MIRT792907	hsa-miR-1285	CLIP-seq
MIRT2477520	hsa-miR-1286	CLIP-seq
MIRT2477521	hsa-miR-1323	CLIP-seq
MIRT2173814	hsa-miR-1324	CLIP-seq
MIRT792913	hsa-miR-144	CLIP-seq
MIRT1545468	hsa-miR-145	CLIP-seq
MIRT2477522	hsa-miR-148a	CLIP-seq
MIRT2477523	hsa-miR-148b	CLIP-seq
MIRT2477524	hsa-miR-152	CLIP-seq
MIRT2477525	hsa-miR-186	CLIP-seq
MIRT1933984	hsa-miR-197	CLIP-seq
MIRT2173818	hsa-miR-2278	CLIP-seq
MIRT2173820	hsa-miR-2467-3p	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT2477526	hsa-miR-3065-5p	CLIP-seq
MIRT2477527	hsa-miR-3115	CLIP-seq
MIRT792921	hsa-miR-3117-5p	CLIP-seq
MIRT2477528	hsa-miR-3133	CLIP-seq
MIRT1545469	hsa-miR-3150a-5p	CLIP-seq
MIRT1545470	hsa-miR-3150b-5p	CLIP-seq
MIRT792923	hsa-miR-3160-5p	CLIP-seq
MIRT2477529	hsa-miR-3163	CLIP-seq
MIRT1545471	hsa-miR-3180-5p	CLIP-seq
MIRT792924	hsa-miR-3187-5p	CLIP-seq
MIRT1933985	hsa-miR-3199	CLIP-seq
MIRT2477530	hsa-miR-3646	CLIP-seq
MIRT2173824	hsa-miR-3655	CLIP-seq
MIRT2477531	hsa-miR-3658	CLIP-seq
MIRT1933988	hsa-miR-3659	CLIP-seq
MIRT2173825	hsa-miR-3686	CLIP-seq
MIRT1933989	hsa-miR-371b-5p	CLIP-seq
MIRT792932	hsa-miR-378g	CLIP-seq
MIRT792934	hsa-miR-3919	CLIP-seq
MIRT792935	hsa-miR-3945	CLIP-seq
MIRT2477532	hsa-miR-409-3p	CLIP-seq
MIRT2173828	hsa-miR-410	CLIP-seq
MIRT792936	hsa-miR-4253	CLIP-seq
MIRT2173829	hsa-miR-4263	CLIP-seq
MIRT2477533	hsa-miR-4272	CLIP-seq
MIRT2477534	hsa-miR-4307	CLIP-seq
MIRT2173834	hsa-miR-4311	CLIP-seq
MIRT792938	hsa-miR-4314	CLIP-seq
MIRT1933990	hsa-miR-4432	CLIP-seq
MIRT792940	hsa-miR-4438	CLIP-seq
MIRT2173836	hsa-miR-4468	CLIP-seq
MIRT1933992	hsa-miR-4475	CLIP-seq
MIRT792943	hsa-miR-4486	CLIP-seq
MIRT2173838	hsa-miR-4495	CLIP-seq
MIRT2173839	hsa-miR-4496	CLIP-seq
MIRT2477535	hsa-miR-4511	CLIP-seq
MIRT1933993	hsa-miR-4515	CLIP-seq
MIRT792946	hsa-miR-452	CLIP-seq
MIRT1933994	hsa-miR-4668-3p	CLIP-seq
MIRT792950	hsa-miR-4676-3p	CLIP-seq
MIRT1933995	hsa-miR-4684-3p	CLIP-seq
MIRT1933996	hsa-miR-4698	CLIP-seq
MIRT1545472	hsa-miR-4712-5p	CLIP-seq
MIRT2477536	hsa-miR-4722-5p	CLIP-seq
MIRT2173842	hsa-miR-4738-5p	CLIP-seq
MIRT2477537	hsa-miR-4766-3p	CLIP-seq
MIRT2173843	hsa-miR-4778-5p	CLIP-seq
MIRT1933998	hsa-miR-499-5p	CLIP-seq
MIRT2173844	hsa-miR-511	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT792958	hsa-miR-520a-5p	CLIP-seq
MIRT792959	hsa-miR-525-5p	CLIP-seq
MIRT792960	hsa-miR-539	CLIP-seq
MIRT792961	hsa-miR-544	CLIP-seq
MIRT2173845	hsa-miR-548c-3p	CLIP-seq
MIRT2477538	hsa-miR-548o	CLIP-seq
MIRT2477539	hsa-miR-548p	CLIP-seq
MIRT2477540	hsa-miR-570	CLIP-seq
MIRT2173850	hsa-miR-583	CLIP-seq
MIRT2477541	hsa-miR-605	CLIP-seq
MIRT792967	hsa-miR-612	CLIP-seq
MIRT1934000	hsa-miR-634	CLIP-seq
MIRT2173854	hsa-miR-656	CLIP-seq
MIRT2173855	hsa-miR-766	CLIP-seq
MIRT792970	hsa-miR-767-3p	CLIP-seq
MIRT1545473	hsa-miR-770-5p	CLIP-seq
MIRT2173856	hsa-miR-889	CLIP-seq
MIRT2477542	hsa-miR-95	CLIP-seq
MIRT792904	hsa-miR-1208	CLIP-seq
MIRT1933982	hsa-miR-122	CLIP-seq
MIRT1933983	hsa-miR-1226	CLIP-seq
MIRT792906	hsa-miR-128	CLIP-seq
MIRT792907	hsa-miR-1285	CLIP-seq
MIRT2477521	hsa-miR-1323	CLIP-seq
MIRT2173814	hsa-miR-1324	CLIP-seq
MIRT792913	hsa-miR-144	CLIP-seq
MIRT1545468	hsa-miR-145	CLIP-seq
MIRT1933984	hsa-miR-197	CLIP-seq
MIRT792917	hsa-miR-27a	CLIP-seq
MIRT792918	hsa-miR-27b	CLIP-seq
MIRT792921	hsa-miR-3117-5p	CLIP-seq
MIRT1545469	hsa-miR-3150a-5p	CLIP-seq
MIRT1545470	hsa-miR-3150b-5p	CLIP-seq
MIRT792923	hsa-miR-3160-5p	CLIP-seq
MIRT1545471	hsa-miR-3180-5p	CLIP-seq
MIRT792924	hsa-miR-3187-5p	CLIP-seq
MIRT1933985	hsa-miR-3199	CLIP-seq
MIRT2173824	hsa-miR-3655	CLIP-seq
MIRT1933988	hsa-miR-3659	CLIP-seq
MIRT1933989	hsa-miR-371b-5p	CLIP-seq
MIRT792932	hsa-miR-378g	CLIP-seq
MIRT792934	hsa-miR-3919	CLIP-seq
MIRT792935	hsa-miR-3945	CLIP-seq
MIRT2173828	hsa-miR-410	CLIP-seq
MIRT792936	hsa-miR-4253	CLIP-seq
MIRT792938	hsa-miR-4314	CLIP-seq
MIRT1933990	hsa-miR-4432	CLIP-seq
MIRT792940	hsa-miR-4438	CLIP-seq
MIRT1933992	hsa-miR-4475	CLIP-seq
MIRT792943	hsa-miR-4486	CLIP-seq
MIRT2173839	hsa-miR-4496	CLIP-seq
MIRT1933993	hsa-miR-4515	CLIP-seq
MIRT792946	hsa-miR-452	CLIP-seq
MIRT1933994	hsa-miR-4668-3p	CLIP-seq
MIRT792950	hsa-miR-4676-3p	CLIP-seq
MIRT1933995	hsa-miR-4684-3p	CLIP-seq
MIRT1933996	hsa-miR-4698	CLIP-seq
MIRT1545472	hsa-miR-4712-5p	CLIP-seq
MIRT2173842	hsa-miR-4738-5p	CLIP-seq
MIRT1933998	hsa-miR-499-5p	CLIP-seq
MIRT2173844	hsa-miR-511	CLIP-seq
MIRT792955	hsa-miR-513a-5p	CLIP-seq
MIRT792958	hsa-miR-520a-5p	CLIP-seq
MIRT792959	hsa-miR-525-5p	CLIP-seq
MIRT792960	hsa-miR-539	CLIP-seq
MIRT792961	hsa-miR-544	CLIP-seq
MIRT2173845	hsa-miR-548c-3p	CLIP-seq
MIRT2477538	hsa-miR-548o	CLIP-seq
MIRT792967	hsa-miR-612	CLIP-seq
MIRT1934000	hsa-miR-634	CLIP-seq
MIRT2173855	hsa-miR-766	CLIP-seq
MIRT792970	hsa-miR-767-3p	CLIP-seq
MIRT1545473	hsa-miR-770-5p	CLIP-seq

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IDA	10716990
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IDA	15644318
GO:0005096	Function	GTPase activator activity	IDA	15644318
GO:0005515	Function	Protein binding	IPI	10716990, 15644318, 16417406, 16866877, 18292223, 19020088, 19332778, 19651892, 22084092, 23572552
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA	14973189
GO:0005794	Component	Golgi apparatus	IDA
GO:0005802	Component	Trans-Golgi network	ISS
GO:0005829	Component	Cytosol	IDA	10716990
GO:0006887	Process	Exocytosis	TAS	10212200
GO:0007030	Process	Golgi organization	IMP	17227842, 20360857
GO:0010256	Process	Endomembrane system organization	IMP	20360857
GO:0015031	Process	Protein transport	IEA
GO:0016363	Component	Nuclear matrix	IEA
GO:0017022	Function	Myosin binding	IPI	15644318
GO:0030532	Component	Small nuclear ribonucleoprotein complex	IDA	18292223
GO:0030837	Process	Negative regulation of actin filament polymerization	IMP	22084092
GO:0031175	Process	Neuron projection development	IEA
GO:0032012	Process	Regulation of ARF protein signal transduction	IEA
GO:0034237	Function	Protein kinase A regulatory subunit binding	IDA	12571360
GO:0034260	Process	Negative regulation of GTPase activity	IDA	15644318
GO:0043547	Process	Positive regulation of GTPase activity	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	22084092
GO:0051897	Process	Positive regulation of protein kinase B signaling	IEA
GO:0090284	Process	Positive regulation of protein glycosylation in Golgi	IMP	17227842
GO:0090303	Process	Positive regulation of wound healing	IMP	22084092
GO:2000114	Process	Regulation of establishment of cell polarity	IMP	22084092

MIM	HGNC	e!Ensembl
604141	15772	ENSG00000066777

Protein

UniProt ID

Q9Y6D6

Protein name

Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1)

Protein function

Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure; the function may be independent

PDB

3LTL , 5EE5 , 5J5C

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16213	DCB	28 → 213	Dimerisation and cyclophilin-binding domain of Mon2	Family
PF12783	Sec7_N	419 → 578	Guanine nucleotide exchange factor in Golgi transport N-terminal	Domain
PF01369	Sec7	698 → 882	Sec7 domain	Domain
PF09324	DUF1981	1220 → 1303	Domain of unknown function (DUF1981)	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in placenta, lung, heart, brain, kidney and pancreas.

Sequence

MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKA
GSSTLPPVKSKTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGNAPDST
TPGKKLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYN
IYLASKNLINQTTAKATLTQMLNVIFARMENQALQEAKQMEKERHRQHHHLLQSPVSHHE
PESPQLRYLPPQTVDHISQEHEGDLDLHTNDVDKSLQDDTEPENGSDISSAENEQTEADQ
ATAAETLSKNEVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGT
IEDGSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQ
KDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPIFRTNEMFINA
IKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTS
SFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGM
SNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEKPSEQEMSEIKHPETIN
RYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYL
QEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSA
LRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHS
PQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSSKQN
VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAF
SVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQ
KNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSL
TGTKDQAPDEFVGLGLVGGNVDWKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAI
VDFVRWLCAVSMDELLSTTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGC
NPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCI
AQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKHFPATIDSF
QDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYTSDDMNVAPEDRVWVR
GWFPILFELSCIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFRIVFRIFDNMKL
PEQQTEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSG
TNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPNSGETAPPPPSPVSEK
PLDTISQKSVDIHDSIQPRSVDNRPQAPLVSASAVNEEVSKIKSTAKFPEQKLFAALLIK
CVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFDVRVDTQDQGMYRFLTSQQLF
KLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYMD
ESRVSAWEEVQQRLLNVCSEALSYFLTLTSESHREAWTNLLLLFLTKVLKISDNRFKAHA
SFYYPLLCEIMQFDLIPELRAVLRRFFLRIGVVFQISQPPEQELGINKQ

Sequence length

1849

Interactions

View interactions

	KEGG
	Endocytosis

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)
Joubert syndrome	JOUBERT SYNDROME 21	rs201108965, rs13297509, rs121918128, rs121918129, rs121918130, rs2109050324, rs118204052, rs118204053, rs121918197, rs121918198, rs121918199, rs121918200, rs121918204, rs387906243, rs145665129 View all (432 more)	26092869

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Alzheimer disease	Alzheimer disease			GWAS

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	21871176
Breast Neoplasms	Inhibit	26474971
Delayed Cranial Ossification due to CBFB Haploinsufficiency	Associate	34113008
Developmental Disabilities	Associate	34113008
Epilepsy	Associate	34113008
Intellectual Disability	Associate	34113008
Mental Disorders	Associate	34113008
Neoplasms	Associate	21871176
Neoplasms	Inhibit	26474971
Uterine Cervical Neoplasms	Associate	35048795

ARFGEF1 (ARF guanine nucleotide exchange factor 1)