Gene Gene information from NCBI Gene database.
Entrez ID 10553
Gene name HIV-1 Tat interactive protein 2
Gene symbol HTATIP2
Synonyms (NCBI Gene)
CC3SDR44U1TIP30
Chromosome 11
Chromosome location 11p15.1
miRNA miRNA information provided by mirtarbase database.
218
miRTarBase ID miRNA Experiments Reference
MIRT002630 hsa-miR-124-3p Microarray 15685193
MIRT002630 hsa-miR-124-3p Microarray 15685193
MIRT002630 hsa-miR-124-3p Microarray 18668037
MIRT437374 hsa-miR-10b-5p Luciferase reporter assayqRT-PCRWestern blot 24096486
MIRT437374 hsa-miR-10b-5p Luciferase reporter assayqRT-PCRWestern blot 24096486
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0003824 Function Catalytic activity IEA
GO:0004674 Function Protein serine/threonine kinase activity IDA 10698937
GO:0005515 Function Protein binding IPI 15282309, 30614533, 32296183
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IDA 15282309
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605628 16637 ENSG00000109854
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BUP3
Protein name Protein HTATIP2 (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2)
Protein function Represses translation by preventing reactivation of elongation factor eEF1A (By similarity). May also inhibit nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors (PubMed:15282309). Ha
PDB 2BKA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13460 NAD_binding_10 25 214 NAD(P)H-binding Domain
Tissue specificity TISSUE SPECIFICITY: High levels in liver, lung, skeletal muscle, pancreas and placenta (PubMed:9174052). Moderate levels in heart and kidney (PubMed:9174052). Low levels in brain (PubMed:9174052). Not expressed or low levels in variant small cell lung car
Sequence
Sequence length 242
Interactions View interactions