Gene Gene information from NCBI Gene database.
Entrez ID 10550
Gene name ARF like GTPase 6 interacting protein 5
Gene symbol ARL6IP5
Synonyms (NCBI Gene)
DERP11GTRAP3-18HSPC127JWAPRAF3Yip6baddicsinhp22jmx
Chromosome 3
Chromosome location 3p14.1
Summary Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell me
miRNA miRNA information provided by mirtarbase database.
379
miRTarBase ID miRNA Experiments Reference
MIRT021065 hsa-miR-155-5p Proteomics 18668040
MIRT021065 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT021502 hsa-miR-145-5p Reporter assay;Microarray 21351259
MIRT038939 hsa-miR-31-3p CLASH 23622248
MIRT021065 hsa-miR-155-5p HITS-CLIP 22473208
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
ING4 Activation 24157826
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26
GO ID Ontology Definition Evidence Reference
GO:0002037 Process Negative regulation of L-glutamate import across plasma membrane IEA
GO:0002037 Process Negative regulation of L-glutamate import across plasma membrane ISS
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005737 Component Cytoplasm IEA
GO:0005783 Component Endoplasmic reticulum IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605709 16937 ENSG00000144746
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75915
Protein name PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-int
Protein function Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. Plays a role in the retention of SLC1A1/
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03208 PRA1 3 150 PRA1 family protein Family
Sequence
Sequence length 188
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Glutamate Neurotransmitter Release Cycle