Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
105372267
Gene name Gene Name - the full gene name approved by the HGNC.
NFIL3 like basic leucine zipper
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NFILZ
Synonyms (NCBI Gene) Gene synonyms aliases
LINC01862
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.2
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0003700 Function DNA-binding transcription factor activity IEA
GO:0005634 Component Nucleus IEA
GO:0006355 Process Regulation of transcription, DNA-templated IEA
GO:0006366 Process Transcription by RNA polymerase II IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
UniProt ID A0A5F9ZHS7
Protein name NFIL3 like protein (NFIL3 like basic leucine zipper)
Family and domains
Sequence
MDVGFSGLPDVSQSHSKTLWGARGRGPSIRRQREFMPEEKKDTVYWEKRRKNNEAAKRSR
EKRRLNDAAIEGRLAALMEENALLKGELKALKLRFGLLPLTGGPRALPLQALLLEAPWTG
DPRPGAEALSSLSGSHSCLLRPRSLDAGIPGCRGCLLAPRWTGLATSPRSPQESASPTLN
RIDMALQTALPPALFSCHLLEGHVGSRPELRPCWGLWSPVPSGCRASGPSDVLLTPTADP
MGLSPGVTCPAPGNSPEGLGQPSLPHKLRIKSRASGRVPRGWEGGQAPL
Sequence length 289
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Asthma Asthma, Childhood asthma 30929738 ClinVar, GWAS
Dermatitis Dermatitis GWAS
Eczema Eczema GWAS
Colorectal Cancer Colorectal Cancer In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. GWAS, CBGDA