Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10533
Gene name Gene Name - the full gene name approved by the HGNC.	Autophagy related 7
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ATG7
Synonyms (NCBI Gene) Gene synonyms aliases	APG7-LIKE, APG7L, GSA7, SCAR31
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p25.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associate

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020034	hsa-miR-375	Microarray	20215506
MIRT036161	hsa-miR-320c	CLASH	23622248
MIRT053396	hsa-miR-96-5p	Microarray	23807165
MIRT497067	hsa-miR-4640-3p	PAR-CLIP	22291592
MIRT494598	hsa-miR-6895-5p	PAR-CLIP	22291592
MIRT497066	hsa-miR-6783-5p	PAR-CLIP	22291592
MIRT494596	hsa-miR-3918	PAR-CLIP	22291592
MIRT497065	hsa-miR-1266-5p	PAR-CLIP	22291592
MIRT497064	hsa-miR-4518	PAR-CLIP	22291592
MIRT497063	hsa-miR-6879-3p	PAR-CLIP	22291592
MIRT497062	hsa-miR-6802-3p	PAR-CLIP	22291592
MIRT497061	hsa-miR-3127-5p	PAR-CLIP	22291592
MIRT495433	hsa-miR-154-5p	PAR-CLIP	23708386
MIRT495432	hsa-miR-4753-5p	PAR-CLIP	23708386
MIRT495431	hsa-miR-451b	PAR-CLIP	23708386
MIRT495430	hsa-miR-3922-5p	PAR-CLIP	23708386
MIRT495429	hsa-miR-6826-5p	PAR-CLIP	23708386
MIRT495428	hsa-miR-4708-3p	PAR-CLIP	23708386
MIRT494599	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT494598	hsa-miR-6895-5p	PAR-CLIP	23592263
MIRT494597	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT494596	hsa-miR-3918	PAR-CLIP	23592263
MIRT494595	hsa-miR-4685-5p	PAR-CLIP	23592263
MIRT494594	hsa-miR-6837-5p	PAR-CLIP	23592263
MIRT494593	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT494591	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT494592	hsa-miR-6749-3p	PAR-CLIP	23592263
MIRT494590	hsa-miR-4687-5p	PAR-CLIP	23592263
MIRT733227	hsa-miR-129-5p	Immunoprecipitaion (IP), Luciferase reporter assay, RNA-seq, qRT-PCR	33637694
MIRT734335	hsa-miR-542-5p	Luciferase reporter assay, Western blotting	33394350
MIRT735427	hsa-miR-4802-3p	qRT-PCR	33160314
MIRT735533	hsa-miR-20a-5p	Immunofluorescence, Immunoprecipitaion (IP), Luciferase reporter assay, qRT-PCR, Western blotting	32661238
MIRT733227	hsa-miR-129-5p	Luciferase reporter assay, Western blotting, qRT-PCR	31781210
MIRT497067	hsa-miR-4640-3p	PAR-CLIP	22291592
MIRT494598	hsa-miR-6895-5p	PAR-CLIP	22291592
MIRT497066	hsa-miR-6783-5p	PAR-CLIP	22291592
MIRT494596	hsa-miR-3918	PAR-CLIP	22291592
MIRT497065	hsa-miR-1266-5p	PAR-CLIP	22291592
MIRT497064	hsa-miR-4518	PAR-CLIP	22291592
MIRT497063	hsa-miR-6879-3p	PAR-CLIP	22291592
MIRT497062	hsa-miR-6802-3p	PAR-CLIP	22291592
MIRT497061	hsa-miR-3127-5p	PAR-CLIP	22291592
MIRT495433	hsa-miR-154-5p	PAR-CLIP	23708386
MIRT495432	hsa-miR-4753-5p	PAR-CLIP	23708386
MIRT495431	hsa-miR-451b	PAR-CLIP	23708386
MIRT495430	hsa-miR-3922-5p	PAR-CLIP	23708386
MIRT495429	hsa-miR-6826-5p	PAR-CLIP	23708386
MIRT495428	hsa-miR-4708-3p	PAR-CLIP	23708386
MIRT494599	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT494598	hsa-miR-6895-5p	PAR-CLIP	23592263
MIRT494597	hsa-miR-4733-3p	PAR-CLIP	23592263
MIRT494596	hsa-miR-3918	PAR-CLIP	23592263
MIRT494595	hsa-miR-4685-5p	PAR-CLIP	23592263
MIRT494594	hsa-miR-6837-5p	PAR-CLIP	23592263
MIRT494593	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT494591	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT494592	hsa-miR-6749-3p	PAR-CLIP	23592263
MIRT494590	hsa-miR-4687-5p	PAR-CLIP	23592263
MIRT756064	hsa-miR-20b-5p	Luciferase reporter assay, Western blotting, qRT-PCR	36090477
MIRT756231	hsa-miR-188-3p	Luciferase reporter assay, Western blotting, qRT-PCR	36846012
MIRT805592	hsa-miR-1250	CLIP-seq
MIRT805593	hsa-miR-1285	CLIP-seq
MIRT805594	hsa-miR-1343	CLIP-seq
MIRT805595	hsa-miR-1915	CLIP-seq
MIRT805596	hsa-miR-193a-3p	CLIP-seq
MIRT805597	hsa-miR-193b	CLIP-seq
MIRT805598	hsa-miR-203	CLIP-seq
MIRT805599	hsa-miR-2467-3p	CLIP-seq
MIRT805600	hsa-miR-3122	CLIP-seq
MIRT805601	hsa-miR-3156-3p	CLIP-seq
MIRT805602	hsa-miR-3187-5p	CLIP-seq
MIRT805603	hsa-miR-3192	CLIP-seq
MIRT805604	hsa-miR-326	CLIP-seq
MIRT805605	hsa-miR-330-5p	CLIP-seq
MIRT805606	hsa-miR-3689a-3p	CLIP-seq
MIRT805607	hsa-miR-3689c	CLIP-seq
MIRT805608	hsa-miR-3691-3p	CLIP-seq
MIRT805609	hsa-miR-378g	CLIP-seq
MIRT805610	hsa-miR-3913-5p	CLIP-seq
MIRT805611	hsa-miR-4301	CLIP-seq
MIRT805612	hsa-miR-4314	CLIP-seq
MIRT805613	hsa-miR-4434	CLIP-seq
MIRT805614	hsa-miR-4467	CLIP-seq
MIRT805615	hsa-miR-4516	CLIP-seq
MIRT805616	hsa-miR-4646-5p	CLIP-seq
MIRT805617	hsa-miR-4701-5p	CLIP-seq
MIRT805618	hsa-miR-4726-3p	CLIP-seq
MIRT805619	hsa-miR-4728-5p	CLIP-seq
MIRT805620	hsa-miR-4746-3p	CLIP-seq
MIRT805621	hsa-miR-4751	CLIP-seq
MIRT805622	hsa-miR-4802-5p	CLIP-seq
MIRT805623	hsa-miR-483-3p	CLIP-seq
MIRT805624	hsa-miR-532-3p	CLIP-seq
MIRT805625	hsa-miR-579	CLIP-seq
MIRT805626	hsa-miR-588	CLIP-seq
MIRT805627	hsa-miR-612	CLIP-seq
MIRT805628	hsa-miR-625	CLIP-seq
MIRT805629	hsa-miR-765	CLIP-seq
MIRT805630	hsa-miR-922	CLIP-seq
MIRT1937892	hsa-miR-126	CLIP-seq
MIRT805593	hsa-miR-1285	CLIP-seq
MIRT805594	hsa-miR-1343	CLIP-seq
MIRT1937893	hsa-miR-141	CLIP-seq
MIRT1937894	hsa-miR-1912	CLIP-seq
MIRT805596	hsa-miR-193a-3p	CLIP-seq
MIRT805597	hsa-miR-193b	CLIP-seq
MIRT1937895	hsa-miR-200a	CLIP-seq
MIRT1937896	hsa-miR-204	CLIP-seq
MIRT1937897	hsa-miR-211	CLIP-seq
MIRT805599	hsa-miR-2467-3p	CLIP-seq
MIRT1937898	hsa-miR-3130-5p	CLIP-seq
MIRT805602	hsa-miR-3187-5p	CLIP-seq
MIRT1937899	hsa-miR-4267	CLIP-seq
MIRT1937900	hsa-miR-4279	CLIP-seq
MIRT1937901	hsa-miR-4482	CLIP-seq
MIRT1937902	hsa-miR-4638-5p	CLIP-seq
MIRT805617	hsa-miR-4701-5p	CLIP-seq
MIRT805623	hsa-miR-483-3p	CLIP-seq
MIRT805626	hsa-miR-588	CLIP-seq
MIRT805627	hsa-miR-612	CLIP-seq
MIRT805628	hsa-miR-625	CLIP-seq
MIRT805630	hsa-miR-922	CLIP-seq
MIRT2177416	hsa-miR-1208	CLIP-seq
MIRT2177417	hsa-miR-3714	CLIP-seq
MIRT1937899	hsa-miR-4267	CLIP-seq
MIRT2177418	hsa-miR-4505	CLIP-seq
MIRT1937902	hsa-miR-4638-5p	CLIP-seq
MIRT2177419	hsa-miR-4704-3p	CLIP-seq
MIRT2177420	hsa-miR-4731-5p	CLIP-seq
MIRT805628	hsa-miR-625	CLIP-seq
MIRT2177421	hsa-miR-892b	CLIP-seq
MIRT2444173	hsa-miR-10a	CLIP-seq
MIRT2444174	hsa-miR-10b	CLIP-seq
MIRT2444175	hsa-miR-1205	CLIP-seq
MIRT2444176	hsa-miR-1207-3p	CLIP-seq
MIRT2444177	hsa-miR-1207-5p	CLIP-seq
MIRT2444178	hsa-miR-1224-3p	CLIP-seq
MIRT2444179	hsa-miR-1236	CLIP-seq
MIRT2444180	hsa-miR-1238	CLIP-seq
MIRT2444181	hsa-miR-1245b-5p	CLIP-seq
MIRT805592	hsa-miR-1250	CLIP-seq
MIRT2444182	hsa-miR-1256	CLIP-seq
MIRT2444183	hsa-miR-1260	CLIP-seq
MIRT2444184	hsa-miR-1260b	CLIP-seq
MIRT2444185	hsa-miR-1262	CLIP-seq
MIRT2444186	hsa-miR-1267	CLIP-seq
MIRT2444187	hsa-miR-1271	CLIP-seq
MIRT2444188	hsa-miR-1280	CLIP-seq
MIRT2444189	hsa-miR-129-3p	CLIP-seq
MIRT2444190	hsa-miR-133a	CLIP-seq
MIRT2444191	hsa-miR-133b	CLIP-seq
MIRT2444192	hsa-miR-146a	CLIP-seq
MIRT2444193	hsa-miR-146b-5p	CLIP-seq
MIRT2444194	hsa-miR-181a	CLIP-seq
MIRT2444195	hsa-miR-181b	CLIP-seq
MIRT2444196	hsa-miR-181c	CLIP-seq
MIRT2444197	hsa-miR-181d	CLIP-seq
MIRT2444198	hsa-miR-182	CLIP-seq
MIRT2444199	hsa-miR-1827	CLIP-seq
MIRT2444200	hsa-miR-186	CLIP-seq
MIRT2444201	hsa-miR-190	CLIP-seq
MIRT2444202	hsa-miR-190b	CLIP-seq
MIRT805595	hsa-miR-1915	CLIP-seq
MIRT2444203	hsa-miR-192	CLIP-seq
MIRT2444204	hsa-miR-1972	CLIP-seq
MIRT1937896	hsa-miR-204	CLIP-seq
MIRT2444205	hsa-miR-2053	CLIP-seq
MIRT2444206	hsa-miR-210	CLIP-seq
MIRT1937897	hsa-miR-211	CLIP-seq
MIRT2444207	hsa-miR-2115	CLIP-seq
MIRT2444208	hsa-miR-215	CLIP-seq
MIRT2444209	hsa-miR-217	CLIP-seq
MIRT805599	hsa-miR-2467-3p	CLIP-seq
MIRT2444210	hsa-miR-2467-5p	CLIP-seq
MIRT2444211	hsa-miR-2682	CLIP-seq
MIRT2444212	hsa-miR-2861	CLIP-seq
MIRT2444213	hsa-miR-298	CLIP-seq
MIRT2444214	hsa-miR-3120-5p	CLIP-seq
MIRT2444215	hsa-miR-3126-3p	CLIP-seq
MIRT2444216	hsa-miR-3133	CLIP-seq
MIRT2444217	hsa-miR-3136-3p	CLIP-seq
MIRT2444218	hsa-miR-3137	CLIP-seq
MIRT2444219	hsa-miR-3142	CLIP-seq
MIRT2444220	hsa-miR-3148	CLIP-seq
MIRT2444221	hsa-miR-3154	CLIP-seq
MIRT805601	hsa-miR-3156-3p	CLIP-seq
MIRT2444222	hsa-miR-3162-3p	CLIP-seq
MIRT2444223	hsa-miR-3169	CLIP-seq
MIRT2444224	hsa-miR-3170	CLIP-seq
MIRT2444225	hsa-miR-3179	CLIP-seq
MIRT2444226	hsa-miR-3185	CLIP-seq
MIRT805603	hsa-miR-3192	CLIP-seq
MIRT2444227	hsa-miR-324-5p	CLIP-seq
MIRT2444228	hsa-miR-331-3p	CLIP-seq
MIRT2444229	hsa-miR-331-5p	CLIP-seq
MIRT2444230	hsa-miR-339-5p	CLIP-seq
MIRT2444231	hsa-miR-342-5p	CLIP-seq
MIRT2444232	hsa-miR-345	CLIP-seq
MIRT2444233	hsa-miR-346	CLIP-seq
MIRT2444234	hsa-miR-3605-3p	CLIP-seq
MIRT2444235	hsa-miR-3607-5p	CLIP-seq
MIRT2444236	hsa-miR-3612	CLIP-seq
MIRT2444237	hsa-miR-3653	CLIP-seq
MIRT2444238	hsa-miR-3657	CLIP-seq
MIRT2444239	hsa-miR-3668	CLIP-seq
MIRT2444240	hsa-miR-3674	CLIP-seq
MIRT2444241	hsa-miR-3686	CLIP-seq
MIRT2444242	hsa-miR-3689a-5p	CLIP-seq
MIRT2444243	hsa-miR-3689b	CLIP-seq
MIRT2444244	hsa-miR-3689d	CLIP-seq
MIRT2444245	hsa-miR-3689e	CLIP-seq
MIRT2444246	hsa-miR-3689f	CLIP-seq
MIRT2177417	hsa-miR-3714	CLIP-seq
MIRT805609	hsa-miR-378g	CLIP-seq
MIRT2444247	hsa-miR-3913-3p	CLIP-seq
MIRT2444248	hsa-miR-3919	CLIP-seq
MIRT2444249	hsa-miR-3943	CLIP-seq
MIRT2444250	hsa-miR-3978	CLIP-seq
MIRT2444251	hsa-miR-4254	CLIP-seq
MIRT2444252	hsa-miR-4256	CLIP-seq
MIRT2444253	hsa-miR-4262	CLIP-seq
MIRT1937899	hsa-miR-4267	CLIP-seq
MIRT2444254	hsa-miR-4268	CLIP-seq
MIRT1937900	hsa-miR-4279	CLIP-seq
MIRT2444255	hsa-miR-4283	CLIP-seq
MIRT2444256	hsa-miR-4284	CLIP-seq
MIRT2444257	hsa-miR-4287	CLIP-seq
MIRT2444258	hsa-miR-4288	CLIP-seq
MIRT2444259	hsa-miR-4292	CLIP-seq
MIRT805611	hsa-miR-4301	CLIP-seq
MIRT2444260	hsa-miR-4308	CLIP-seq
MIRT2444261	hsa-miR-4313	CLIP-seq
MIRT805612	hsa-miR-4314	CLIP-seq
MIRT2444262	hsa-miR-4328	CLIP-seq
MIRT2444263	hsa-miR-4418	CLIP-seq
MIRT2444264	hsa-miR-4421	CLIP-seq
MIRT2444265	hsa-miR-4448	CLIP-seq
MIRT2444266	hsa-miR-4452	CLIP-seq
MIRT2444267	hsa-miR-4455	CLIP-seq
MIRT2444268	hsa-miR-4457	CLIP-seq
MIRT805614	hsa-miR-4467	CLIP-seq
MIRT2444269	hsa-miR-4468	CLIP-seq
MIRT2444270	hsa-miR-4496	CLIP-seq
MIRT2444271	hsa-miR-449c	CLIP-seq
MIRT2444272	hsa-miR-450b-5p	CLIP-seq
MIRT2444273	hsa-miR-4515	CLIP-seq
MIRT2444274	hsa-miR-4519	CLIP-seq
MIRT2444275	hsa-miR-452	CLIP-seq
MIRT2444276	hsa-miR-4642	CLIP-seq
MIRT805616	hsa-miR-4646-5p	CLIP-seq
MIRT2444277	hsa-miR-4648	CLIP-seq
MIRT2444278	hsa-miR-4650-5p	CLIP-seq
MIRT2444279	hsa-miR-4651	CLIP-seq
MIRT2444280	hsa-miR-4652-3p	CLIP-seq
MIRT2444281	hsa-miR-4654	CLIP-seq
MIRT2444282	hsa-miR-4664-5p	CLIP-seq
MIRT2444283	hsa-miR-4669	CLIP-seq
MIRT2444284	hsa-miR-4670-3p	CLIP-seq
MIRT2444285	hsa-miR-4676-3p	CLIP-seq
MIRT2444286	hsa-miR-4677-3p	CLIP-seq
MIRT2444287	hsa-miR-4678	CLIP-seq
MIRT2444288	hsa-miR-4679	CLIP-seq
MIRT2444289	hsa-miR-4685-3p	CLIP-seq
MIRT2444290	hsa-miR-4694-5p	CLIP-seq
MIRT2444291	hsa-miR-4695-5p	CLIP-seq
MIRT2444292	hsa-miR-4701-3p	CLIP-seq
MIRT2444293	hsa-miR-4709-3p	CLIP-seq
MIRT2444294	hsa-miR-4711-3p	CLIP-seq
MIRT805618	hsa-miR-4726-3p	CLIP-seq
MIRT2444295	hsa-miR-4729	CLIP-seq
MIRT2177420	hsa-miR-4731-5p	CLIP-seq
MIRT2444296	hsa-miR-4736	CLIP-seq
MIRT2444297	hsa-miR-4738-3p	CLIP-seq
MIRT805620	hsa-miR-4746-3p	CLIP-seq
MIRT2444298	hsa-miR-4753-3p	CLIP-seq
MIRT2444299	hsa-miR-4763-3p	CLIP-seq
MIRT2444300	hsa-miR-4763-5p	CLIP-seq
MIRT2444301	hsa-miR-4769-5p	CLIP-seq
MIRT2444302	hsa-miR-4775	CLIP-seq
MIRT2444303	hsa-miR-4786-5p	CLIP-seq
MIRT2444304	hsa-miR-4796-3p	CLIP-seq
MIRT2444305	hsa-miR-4797-5p	CLIP-seq
MIRT805623	hsa-miR-483-3p	CLIP-seq
MIRT2444306	hsa-miR-486-3p	CLIP-seq
MIRT2444307	hsa-miR-489	CLIP-seq
MIRT2444308	hsa-miR-502-5p	CLIP-seq
MIRT2444309	hsa-miR-507	CLIP-seq
MIRT2444310	hsa-miR-509-3-5p	CLIP-seq
MIRT2444311	hsa-miR-509-5p	CLIP-seq
MIRT2444312	hsa-miR-513b	CLIP-seq
MIRT2444313	hsa-miR-516a-3p	CLIP-seq
MIRT805624	hsa-miR-532-3p	CLIP-seq
MIRT2444314	hsa-miR-539	CLIP-seq
MIRT2444315	hsa-miR-548c-3p	CLIP-seq
MIRT2444316	hsa-miR-548q	CLIP-seq
MIRT2444317	hsa-miR-548t	CLIP-seq
MIRT2444318	hsa-miR-556-3p	CLIP-seq
MIRT2444319	hsa-miR-557	CLIP-seq
MIRT2444320	hsa-miR-569	CLIP-seq
MIRT2444321	hsa-miR-580	CLIP-seq
MIRT2444322	hsa-miR-582-5p	CLIP-seq
MIRT2444323	hsa-miR-589	CLIP-seq
MIRT2444324	hsa-miR-592	CLIP-seq
MIRT2444325	hsa-miR-599	CLIP-seq
MIRT2444326	hsa-miR-604	CLIP-seq
MIRT2444327	hsa-miR-608	CLIP-seq
MIRT2444328	hsa-miR-632	CLIP-seq
MIRT2444329	hsa-miR-643	CLIP-seq
MIRT2444330	hsa-miR-647	CLIP-seq
MIRT2444331	hsa-miR-650	CLIP-seq
MIRT2444332	hsa-miR-653	CLIP-seq
MIRT2444333	hsa-miR-661	CLIP-seq
MIRT2444334	hsa-miR-759	CLIP-seq
MIRT2444335	hsa-miR-760	CLIP-seq
MIRT805629	hsa-miR-765	CLIP-seq
MIRT2444336	hsa-miR-769-5p	CLIP-seq
MIRT805630	hsa-miR-922	CLIP-seq
MIRT2444337	hsa-miR-940	CLIP-seq
MIRT2444338	hsa-miR-942	CLIP-seq
MIRT2444339	hsa-miR-96	CLIP-seq
MIRT2444175	hsa-miR-1205	CLIP-seq
MIRT2444178	hsa-miR-1224-3p	CLIP-seq
MIRT2444180	hsa-miR-1238	CLIP-seq
MIRT2444181	hsa-miR-1245b-5p	CLIP-seq
MIRT2444182	hsa-miR-1256	CLIP-seq
MIRT2444183	hsa-miR-1260	CLIP-seq
MIRT2444184	hsa-miR-1260b	CLIP-seq
MIRT2444185	hsa-miR-1262	CLIP-seq
MIRT2444187	hsa-miR-1271	CLIP-seq
MIRT2444188	hsa-miR-1280	CLIP-seq
MIRT2464888	hsa-miR-1291	CLIP-seq
MIRT2444189	hsa-miR-129-3p	CLIP-seq
MIRT2444190	hsa-miR-133a	CLIP-seq
MIRT2444191	hsa-miR-133b	CLIP-seq
MIRT2444192	hsa-miR-146a	CLIP-seq
MIRT2444193	hsa-miR-146b-5p	CLIP-seq
MIRT2444194	hsa-miR-181a	CLIP-seq
MIRT2444195	hsa-miR-181b	CLIP-seq
MIRT2444196	hsa-miR-181c	CLIP-seq
MIRT2444197	hsa-miR-181d	CLIP-seq
MIRT2444198	hsa-miR-182	CLIP-seq
MIRT2444201	hsa-miR-190	CLIP-seq
MIRT2444202	hsa-miR-190b	CLIP-seq
MIRT2464889	hsa-miR-1914	CLIP-seq
MIRT805595	hsa-miR-1915	CLIP-seq
MIRT2444204	hsa-miR-1972	CLIP-seq
MIRT2444207	hsa-miR-2115	CLIP-seq
MIRT2444211	hsa-miR-2682	CLIP-seq
MIRT2444214	hsa-miR-3120-5p	CLIP-seq
MIRT2464890	hsa-miR-3130-3p	CLIP-seq
MIRT2444218	hsa-miR-3137	CLIP-seq
MIRT2444219	hsa-miR-3142	CLIP-seq
MIRT2444220	hsa-miR-3148	CLIP-seq
MIRT805601	hsa-miR-3156-3p	CLIP-seq
MIRT2464891	hsa-miR-3173-5p	CLIP-seq
MIRT2444227	hsa-miR-324-5p	CLIP-seq
MIRT2444228	hsa-miR-331-3p	CLIP-seq
MIRT2444230	hsa-miR-339-5p	CLIP-seq
MIRT2444231	hsa-miR-342-5p	CLIP-seq
MIRT2444233	hsa-miR-346	CLIP-seq
MIRT2444238	hsa-miR-3657	CLIP-seq
MIRT2444241	hsa-miR-3686	CLIP-seq
MIRT2444242	hsa-miR-3689a-5p	CLIP-seq
MIRT2444243	hsa-miR-3689b	CLIP-seq
MIRT2444244	hsa-miR-3689d	CLIP-seq
MIRT2444245	hsa-miR-3689e	CLIP-seq
MIRT2444246	hsa-miR-3689f	CLIP-seq
MIRT2177417	hsa-miR-3714	CLIP-seq
MIRT805609	hsa-miR-378g	CLIP-seq
MIRT2444247	hsa-miR-3913-3p	CLIP-seq
MIRT2444253	hsa-miR-4262	CLIP-seq
MIRT2444254	hsa-miR-4268	CLIP-seq
MIRT1937900	hsa-miR-4279	CLIP-seq
MIRT2444258	hsa-miR-4288	CLIP-seq
MIRT2444259	hsa-miR-4292	CLIP-seq
MIRT805611	hsa-miR-4301	CLIP-seq
MIRT2444264	hsa-miR-4421	CLIP-seq
MIRT2444265	hsa-miR-4448	CLIP-seq
MIRT2444267	hsa-miR-4455	CLIP-seq
MIRT2444270	hsa-miR-4496	CLIP-seq
MIRT2444271	hsa-miR-449c	CLIP-seq
MIRT2444272	hsa-miR-450b-5p	CLIP-seq
MIRT2444276	hsa-miR-4642	CLIP-seq
MIRT2444278	hsa-miR-4650-5p	CLIP-seq
MIRT2444279	hsa-miR-4651	CLIP-seq
MIRT2444280	hsa-miR-4652-3p	CLIP-seq
MIRT2444282	hsa-miR-4664-5p	CLIP-seq
MIRT2444283	hsa-miR-4669	CLIP-seq
MIRT2444286	hsa-miR-4677-3p	CLIP-seq
MIRT2444288	hsa-miR-4679	CLIP-seq
MIRT2444290	hsa-miR-4694-5p	CLIP-seq
MIRT2444292	hsa-miR-4701-3p	CLIP-seq
MIRT805618	hsa-miR-4726-3p	CLIP-seq
MIRT2444295	hsa-miR-4729	CLIP-seq
MIRT2177420	hsa-miR-4731-5p	CLIP-seq
MIRT2444304	hsa-miR-4796-3p	CLIP-seq
MIRT2444305	hsa-miR-4797-5p	CLIP-seq
MIRT805623	hsa-miR-483-3p	CLIP-seq
MIRT2444307	hsa-miR-489	CLIP-seq
MIRT2444308	hsa-miR-502-5p	CLIP-seq
MIRT2444309	hsa-miR-507	CLIP-seq
MIRT2444313	hsa-miR-516a-3p	CLIP-seq
MIRT805624	hsa-miR-532-3p	CLIP-seq
MIRT2444314	hsa-miR-539	CLIP-seq
MIRT2444315	hsa-miR-548c-3p	CLIP-seq
MIRT2444317	hsa-miR-548t	CLIP-seq
MIRT2444319	hsa-miR-557	CLIP-seq
MIRT2444321	hsa-miR-580	CLIP-seq
MIRT2444323	hsa-miR-589	CLIP-seq
MIRT2444326	hsa-miR-604	CLIP-seq
MIRT2444327	hsa-miR-608	CLIP-seq
MIRT2444328	hsa-miR-632	CLIP-seq
MIRT2444329	hsa-miR-643	CLIP-seq
MIRT2444330	hsa-miR-647	CLIP-seq
MIRT2444334	hsa-miR-759	CLIP-seq
MIRT2444335	hsa-miR-760	CLIP-seq
MIRT805629	hsa-miR-765	CLIP-seq
MIRT2444339	hsa-miR-96	CLIP-seq
MIRT2444278	hsa-miR-4650-5p	CLIP-seq
MIRT2444305	hsa-miR-4797-5p	CLIP-seq
MIRT2444314	hsa-miR-539	CLIP-seq
MIRT2444175	hsa-miR-1205	CLIP-seq
MIRT2444180	hsa-miR-1238	CLIP-seq
MIRT2444181	hsa-miR-1245b-5p	CLIP-seq
MIRT2464888	hsa-miR-1291	CLIP-seq
MIRT2444200	hsa-miR-186	CLIP-seq
MIRT2444201	hsa-miR-190	CLIP-seq
MIRT2444202	hsa-miR-190b	CLIP-seq
MIRT2464889	hsa-miR-1914	CLIP-seq
MIRT2444206	hsa-miR-210	CLIP-seq
MIRT2444211	hsa-miR-2682	CLIP-seq
MIRT2464890	hsa-miR-3130-3p	CLIP-seq
MIRT2444216	hsa-miR-3133	CLIP-seq
MIRT2480879	hsa-miR-3138	CLIP-seq
MIRT2444219	hsa-miR-3142	CLIP-seq
MIRT2444221	hsa-miR-3154	CLIP-seq
MIRT2464891	hsa-miR-3173-5p	CLIP-seq
MIRT2444225	hsa-miR-3179	CLIP-seq
MIRT2444234	hsa-miR-3605-3p	CLIP-seq
MIRT2444237	hsa-miR-3653	CLIP-seq
MIRT2444238	hsa-miR-3657	CLIP-seq
MIRT2444242	hsa-miR-3689a-5p	CLIP-seq
MIRT2444243	hsa-miR-3689b	CLIP-seq
MIRT2444244	hsa-miR-3689d	CLIP-seq
MIRT2444245	hsa-miR-3689e	CLIP-seq
MIRT2444246	hsa-miR-3689f	CLIP-seq
MIRT2177417	hsa-miR-3714	CLIP-seq
MIRT2444248	hsa-miR-3919	CLIP-seq
MIRT2444249	hsa-miR-3943	CLIP-seq
MIRT2444252	hsa-miR-4256	CLIP-seq
MIRT2444254	hsa-miR-4268	CLIP-seq
MIRT2444255	hsa-miR-4283	CLIP-seq
MIRT2444261	hsa-miR-4313	CLIP-seq
MIRT2444265	hsa-miR-4448	CLIP-seq
MIRT2444271	hsa-miR-449c	CLIP-seq
MIRT2480880	hsa-miR-4522	CLIP-seq
MIRT2444278	hsa-miR-4650-5p	CLIP-seq
MIRT2444283	hsa-miR-4669	CLIP-seq
MIRT2444284	hsa-miR-4670-3p	CLIP-seq
MIRT2444286	hsa-miR-4677-3p	CLIP-seq
MIRT2444288	hsa-miR-4679	CLIP-seq
MIRT2444290	hsa-miR-4694-5p	CLIP-seq
MIRT2444295	hsa-miR-4729	CLIP-seq
MIRT2177420	hsa-miR-4731-5p	CLIP-seq
MIRT2480881	hsa-miR-4752	CLIP-seq
MIRT2444300	hsa-miR-4763-5p	CLIP-seq
MIRT2444303	hsa-miR-4786-5p	CLIP-seq
MIRT2480882	hsa-miR-4793-3p	CLIP-seq
MIRT2444305	hsa-miR-4797-5p	CLIP-seq
MIRT2480883	hsa-miR-4800-5p	CLIP-seq
MIRT2444313	hsa-miR-516a-3p	CLIP-seq
MIRT2444314	hsa-miR-539	CLIP-seq
MIRT2444326	hsa-miR-604	CLIP-seq
MIRT2444329	hsa-miR-643	CLIP-seq
MIRT2444330	hsa-miR-647	CLIP-seq
MIRT2444334	hsa-miR-759	CLIP-seq
MIRT2444335	hsa-miR-760	CLIP-seq
MIRT2444336	hsa-miR-769-5p	CLIP-seq
MIRT2444175	hsa-miR-1205	CLIP-seq
MIRT2444181	hsa-miR-1245b-5p	CLIP-seq
MIRT2464888	hsa-miR-1291	CLIP-seq
MIRT2444190	hsa-miR-133a	CLIP-seq
MIRT2444191	hsa-miR-133b	CLIP-seq
MIRT2464889	hsa-miR-1914	CLIP-seq
MIRT2464890	hsa-miR-3130-3p	CLIP-seq
MIRT2480879	hsa-miR-3138	CLIP-seq
MIRT2444219	hsa-miR-3142	CLIP-seq
MIRT2444221	hsa-miR-3154	CLIP-seq
MIRT2464891	hsa-miR-3173-5p	CLIP-seq
MIRT2444225	hsa-miR-3179	CLIP-seq
MIRT2444228	hsa-miR-331-3p	CLIP-seq
MIRT2444231	hsa-miR-342-5p	CLIP-seq
MIRT2444234	hsa-miR-3605-3p	CLIP-seq
MIRT2444237	hsa-miR-3653	CLIP-seq
MIRT2444244	hsa-miR-3689d	CLIP-seq
MIRT2444249	hsa-miR-3943	CLIP-seq
MIRT2444254	hsa-miR-4268	CLIP-seq
MIRT2444255	hsa-miR-4283	CLIP-seq
MIRT2444259	hsa-miR-4292	CLIP-seq
MIRT2444261	hsa-miR-4313	CLIP-seq
MIRT2444265	hsa-miR-4448	CLIP-seq
MIRT2444267	hsa-miR-4455	CLIP-seq
MIRT2480880	hsa-miR-4522	CLIP-seq
MIRT2444278	hsa-miR-4650-5p	CLIP-seq
MIRT2444279	hsa-miR-4651	CLIP-seq
MIRT2444282	hsa-miR-4664-5p	CLIP-seq
MIRT2444284	hsa-miR-4670-3p	CLIP-seq
MIRT2444295	hsa-miR-4729	CLIP-seq
MIRT2480881	hsa-miR-4752	CLIP-seq
MIRT2444300	hsa-miR-4763-5p	CLIP-seq
MIRT2480882	hsa-miR-4793-3p	CLIP-seq
MIRT2444304	hsa-miR-4796-3p	CLIP-seq
MIRT2444305	hsa-miR-4797-5p	CLIP-seq
MIRT2480883	hsa-miR-4800-5p	CLIP-seq
MIRT2444314	hsa-miR-539	CLIP-seq
MIRT2444317	hsa-miR-548t	CLIP-seq
MIRT2444326	hsa-miR-604	CLIP-seq
MIRT2444327	hsa-miR-608	CLIP-seq
MIRT2444329	hsa-miR-643	CLIP-seq
MIRT2444330	hsa-miR-647	CLIP-seq
MIRT2444334	hsa-miR-759	CLIP-seq
MIRT2444335	hsa-miR-760	CLIP-seq
MIRT805629	hsa-miR-765	CLIP-seq
MIRT2444295	hsa-miR-4729	CLIP-seq
MIRT2444305	hsa-miR-4797-5p	CLIP-seq
MIRT2444314	hsa-miR-539	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
HSF1	Activation	23386620

Show/Hide all(50)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000045	Process	Autophagosome assembly	IBA
GO:0000045	Process	Autophagosome assembly	IDA	37943659
GO:0000045	Process	Autophagosome assembly	IMP	33446636
GO:0000045	Process	Autophagosome assembly	IMP	22170151
GO:0000407	Component	Phagophore assembly site	IBA
GO:0000407	Component	Phagophore assembly site	IDA	37943659
GO:0000407	Component	Phagophore assembly site	IEA
GO:0000423	Process	Mitophagy	IBA
GO:0000423	Process	Mitophagy	IGI	19279012
GO:0005515	Function	Protein binding	IPI	11096062, 11825910, 16303767, 18083104, 18296641, 20195357, 20543840, 20562859, 21903422, 22499945, 24186333, 26043688, 28514442, 32814053, 33961781, 34524948, 37252361
GO:0005576	Component	Extracellular region	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	20543840
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005930	Component	Axoneme	ISS
GO:0006497	Process	Protein lipidation	IDA	12890687
GO:0006914	Process	Autophagy	IEA
GO:0006914	Process	Autophagy	IGI	28389568
GO:0006914	Process	Autophagy	IMP	25327288
GO:0006914	Process	Autophagy	IMP	20543840, 24681637
GO:0006914	Process	Autophagy	ISS
GO:0006995	Process	Cellular response to nitrogen starvation	IBA
GO:0008641	Function	Ubiquitin-like modifier activating enzyme activity	IEA
GO:0009267	Process	Cellular response to starvation	IDA	20543840
GO:0009896	Process	Positive regulation of catabolic process	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016236	Process	Macroautophagy	IMP	22354037
GO:0019778	Function	Atg12 activating enzyme activity	IBA
GO:0019778	Function	Atg12 activating enzyme activity	IDA	37943659
GO:0019778	Function	Atg12 activating enzyme activity	IMP	22170151
GO:0019778	Function	Atg12 activating enzyme activity	ISS	20723759
GO:0019779	Function	Atg8 activating enzyme activity	IBA
GO:0031401	Process	Positive regulation of protein modification process	IDA	12890687
GO:0031667	Process	Response to nutrient levels	IEA
GO:0032446	Process	Protein modification by small protein conjugation	IBA
GO:0033554	Process	Cellular response to stress	IDA	37943659
GO:0034727	Process	Piecemeal microautophagy of the nucleus	IBA
GO:0034774	Component	Secretory granule lumen	TAS
GO:0042752	Process	Regulation of circadian rhythm	ISS
GO:0042803	Function	Protein homodimerization activity	IDA	11096062
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IMP	20543840
GO:0045732	Process	Positive regulation of protein catabolic process	IMP	20543840
GO:0048511	Process	Rhythmic process	IEA
GO:0051607	Process	Defense response to virus	IMP	23290079
GO:0060255	Process	Regulation of macromolecule metabolic process	IEA
GO:0071455	Process	Cellular response to hyperoxia	IDA	20543840
GO:0080090	Process	Regulation of primary metabolic process	IEA
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

MIM	HGNC	e!Ensembl
608760	16935	ENSG00000197548

Protein

UniProt ID

O95352

Protein name

Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)

Protein function

E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phos

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16420	ATG7_N	13 → 323	Ubiquitin-like modifier-activating enzyme ATG7 N-terminus	Domain
PF00899	ThiF	333 → 648	ThiF family	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed, especially in kidney, liver, lymph nodes and bone marrow. {ECO:0000269|PubMed:11890701}.

Sequence

MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLP
ARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTADKKLLLEQAANEIWESIKSGT
ALENPVLLNKFLLLTFADLKKYHFYYWFCYPALCLPESLPLIQGPVGLDQRFSLKQIEAL
ECAYDNLCQTEGVTALPYFLIKYDENMVLVSLLKHYSDFFQGQRTKITIGVYDPCNLAQY
PGWPLRNFLVLAAHRWSSSFQSVEVVCFRDRTMQGARDVAHSIIFEVKLPEMAFSPDCPK
AVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLL
LGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAADR
LQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQLIESHDVVFLLMDTRES
RWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPNHPVASADLLGSSLF
ANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRPGLAVIAGALAVELMVSVLQHPEG
GYAIASSSDDRMNEPPTSLGLVPHQIRGFLSRFDNVLPVSLAFDKCTACSSKVLDQYERE
GFNFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSDDETI

Sequence length

703

Interactions

View interactions

	KEGG		Reactome
	Autophagy - other Autophagy - animal Ferroptosis Neutrophil extracellular trap formation		Macroautophagy Neutrophil degranulation Signaling by BRAF and RAF fusions Antigen processing: Ubiquitination & Proteasome degradation

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Hypertension	Hypertension, High blood pressure / hypertension, Hypertension (PheCode 401), Essential hypertension (PheCode 401.1)	N/A	N/A	GWAS
Insomnia	Insomnia	N/A	N/A	GWAS
Spinocerebellar Ataxia	spinocerebellar ataxia, autosomal recessive 31	N/A	N/A	GenCC

Show/Hide Text Mining Associations (82)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adrenocortical Carcinoma	Associate	35500219
Alzheimer Disease	Associate	29039784
Asthma	Associate	26701229
Atherosclerosis	Associate	35777002, 39741278, 40527779
Atrial Fibrillation	Associate	33706714
Azoospermia Nonobstructive	Associate	35710416
Breast Neoplasms	Associate	19944062, 20083906, 23386620, 25573951
Carcinoma Hepatocellular	Associate	25342595, 29676845, 32964966, 33495541, 34691238, 35405176, 38554427
Carcinoma Merkel Cell	Associate	31180579
Carcinoma Non Small Cell Lung	Associate	27184816, 29481833, 33168592
Carcinoma Renal Cell	Inhibit	24998849
Carcinoma Renal Cell	Associate	26208877, 35812454
Celiac Disease	Associate	28208686
Cerebellar Diseases	Associate	34161705
Cerebral Infarction	Associate	29123153
Chemical and Drug Induced Liver Injury	Associate	35405176
Cholangiocarcinoma	Associate	35725745, 40696630
Colorectal Neoplasms	Associate	26163626, 32046105
Corneal Endothelial Cell Loss	Associate	32792588
Coronary Artery Disease	Associate	35777002
Coronary Disease	Associate	36180886
Developmental Disabilities	Associate	34161705
Diabetes Gestational	Associate	33019392, 33085184, 37311265
Diabetic Retinopathy	Inhibit	37522124
Drug Related Side Effects and Adverse Reactions	Associate	21655094, 23051914, 23700428, 28553083, 33077697, 33495541
Echovirus Infections	Associate	32676816
Endocrine System Diseases	Associate	34161705
Endometrial Neoplasms	Associate	26208877, 40138919
Endometrial Neoplasms	Inhibit	34809787
Endometriosis	Associate	34809787
Facial Dysmorphism with Multiple Malformations	Associate	34161705
Fatty Liver	Associate	35405176
Fibrocartilaginous embolism	Associate	32016953
Fibrosis	Associate	35405176
Glioblastoma	Associate	23792642
Glioma	Associate	28912153
HIV Infections	Associate	30344003, 30653393
HTLV I Infections	Associate	29962265
Huntington Disease	Associate	23894380
Infections	Associate	33016799, 38088554
Inflammation	Associate	26701229, 32792588, 35405176
Intervertebral Disc Degeneration	Associate	33846806
Leiomyoma	Associate	31843092
Leukemia	Associate	22898604
Leukemia Erythroblastic Acute	Associate	27091640
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	25701353
Leukemia Myeloid Acute	Associate	33077697
Leukemia Promyelocytic Acute	Associate	14976209
Liver Diseases	Associate	35405176
Liver Failure	Associate	35405176
Melanoma	Associate	25484078
Metabolic Syndrome	Associate	35405176
Myocardial Infarction	Associate	30407747
Neoplasm Metastasis	Associate	30635654
Neoplasms	Inhibit	14976209, 31180579
Neoplasms	Associate	20368806, 20634405, 23637631, 23792642, 25484078, 25897662, 26208877, 26677873, 29967346, 30238850, 30733195, 30988371, 31545241, 35725745, 37311357, 39253092 View all (1 more)
Non alcoholic Fatty Liver Disease	Associate	35405176
Non alcoholic Fatty Liver Disease	Stimulate	36674839
Obesity	Associate	29400609, 35405176, 37311265
Obesity	Stimulate	36674839
Osteosarcoma	Associate	23527187, 36254233
Ovarian Dysgenesis 2	Associate	30224786
Ovarian Neoplasms	Associate	20508647, 30570864, 39513923
Overweight	Associate	29400609
Pancreatic Neoplasms	Associate	35288538, 35582016
Parkinson Disease	Associate	35802825, 36593912
Poliomyelitis	Associate	33016799
Polycystic Ovary Syndrome	Stimulate	31056990
Primary Ovarian Insufficiency	Associate	30224786, 36099812
Prostatic Neoplasms	Associate	23670050, 37929350
Rectal Neoplasms	Associate	36414988
Sarcoma Ewing	Associate	40628996
Squamous Cell Carcinoma of Head and Neck	Associate	24599075
Stomach Neoplasms	Associate	32139670, 33649532
Stroke	Associate	29123153
Takotsubo Cardiomyopathy	Associate	35405176
Thyroid Neoplasms	Associate	30005868
Triple Negative Breast Neoplasms	Associate	30988371
Tuberculosis	Associate	38088554
Urinary Bladder Neoplasms	Associate	28553083, 30635654
Uterine Cervical Neoplasms	Associate	25803820, 26681037
Vasculitis	Associate	34961976

ATG7 (autophagy related 7)