ADARB2 (adenosine deaminase RNA specific B2 (inactive))
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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105 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Adenosine deaminase RNA specific B2 (inactive) |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ADARB2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ADAR3, RED2 |
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Chromosome
Chromosome number
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10 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10p15.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the double-stranded RNA adenosine deaminase family of RNA-editing enzymes and may play a regulatory role in RNA editing. [provided by RefSeq, Jul 2008] |
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miRNA
miRNA information provided by mirtarbase database.
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| Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q9NS39 | ||||||||||||||||||||
| Protein name | Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2) (dsRNA adenosine deaminase B2) | ||||||||||||||||||||
| Protein function | Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA. | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Brain specific. Expressed at higher levels in astrocytomas as compared to the normal brain tissue. {ECO:0000269|PubMed:10836796, ECO:0000269|PubMed:18178553}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 739 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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