CARM1 (coactivator associated arginine methyltransferase 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10498 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Coactivator associated arginine methyltransferase 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CARM1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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PRMT4 |
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Chromosome
Chromosome number
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19 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated protein |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q86X55 | |||||||||||||||
| Protein name | Histone-arginine methyltransferase CARM1 (EC 2.1.1.319) (Coactivator-associated arginine methyltransferase 1) (Protein arginine N-methyltransferase 4) | |||||||||||||||
| Protein function | Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability (PubMed:12237300, PubMed:16497732, PubMed: | |||||||||||||||
| PDB | 2Y1W , 2Y1X , 4IKP , 5DWQ , 5DX0 , 5DX1 , 5DX8 , 5DXA , 5DXJ , 5U4X , 6ARJ , 6ARV , 6D2L , 6DVR , 6IZQ , 6S70 , 6S71 , 6S74 , 6S77 , 6S79 , 6S7A , 6S7B , 6S7C , 7FAI , 7FAJ , 7U9I , 8G2H , 8G2I , 8SIG , 8SIH | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia. {ECO:0000269|PubMed:15221992}. | |||||||||||||||
| Sequence |
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| Sequence length | 608 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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