Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10489
Gene name Gene Name - the full gene name approved by the HGNC.	Leucine rich repeat containing 41
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LRRC41
Synonyms (NCBI Gene) Gene synonyms aliases	MUF1, PP7759
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p34.1-p33

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016965	hsa-miR-335-5p	Microarray	18185580
MIRT052252	hsa-let-7b-5p	CLASH	23622248
MIRT051581	hsa-let-7e-5p	CLASH	23622248
MIRT050707	hsa-miR-18a-5p	CLASH	23622248
MIRT048516	hsa-miR-100-5p	CLASH	23622248
MIRT048205	hsa-miR-196a-5p	CLASH	23622248
MIRT046461	hsa-miR-15b-5p	CLASH	23622248
MIRT045506	hsa-miR-149-5p	CLASH	23622248
MIRT040052	hsa-miR-615-3p	CLASH	23622248
MIRT038887	hsa-miR-93-3p	CLASH	23622248
MIRT536223	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT536222	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT536221	hsa-miR-548m	PAR-CLIP	22012620
MIRT536220	hsa-miR-6507-5p	PAR-CLIP	22012620
MIRT536219	hsa-miR-5681a	PAR-CLIP	22012620
MIRT536218	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT536223	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT536222	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT536221	hsa-miR-548m	PAR-CLIP	22012620
MIRT536220	hsa-miR-6507-5p	PAR-CLIP	22012620
MIRT536219	hsa-miR-5681a	PAR-CLIP	22012620
MIRT536218	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT2033800	hsa-miR-1915	CLIP-seq
MIRT2033801	hsa-miR-3714	CLIP-seq
MIRT2033802	hsa-miR-3914	CLIP-seq
MIRT2033803	hsa-miR-3922-5p	CLIP-seq
MIRT2033804	hsa-miR-4690-3p	CLIP-seq
MIRT2033805	hsa-miR-4747-5p	CLIP-seq
MIRT2033806	hsa-miR-4779	CLIP-seq
MIRT2033807	hsa-miR-873	CLIP-seq
MIRT2033808	hsa-miR-940	CLIP-seq
MIRT2264216	hsa-miR-214	CLIP-seq
MIRT2264217	hsa-miR-3185	CLIP-seq
MIRT2264218	hsa-miR-3619-5p	CLIP-seq
MIRT2264219	hsa-miR-4530	CLIP-seq
MIRT2264220	hsa-miR-761	CLIP-seq
MIRT2033804	hsa-miR-4690-3p	CLIP-seq
MIRT2563345	hsa-miR-1252	CLIP-seq
MIRT2563346	hsa-miR-130a	CLIP-seq
MIRT2563347	hsa-miR-130b	CLIP-seq
MIRT2563348	hsa-miR-148a	CLIP-seq
MIRT2563349	hsa-miR-148b	CLIP-seq
MIRT2563350	hsa-miR-152	CLIP-seq
MIRT2033800	hsa-miR-1915	CLIP-seq
MIRT2563351	hsa-miR-2861	CLIP-seq
MIRT2563352	hsa-miR-301a	CLIP-seq
MIRT2563353	hsa-miR-301b	CLIP-seq
MIRT2563354	hsa-miR-3136-3p	CLIP-seq
MIRT2563355	hsa-miR-3148	CLIP-seq
MIRT2563356	hsa-miR-3150a-5p	CLIP-seq
MIRT2563357	hsa-miR-3150b-5p	CLIP-seq
MIRT2264217	hsa-miR-3185	CLIP-seq
MIRT2563358	hsa-miR-3666	CLIP-seq
MIRT2033803	hsa-miR-3922-5p	CLIP-seq
MIRT2563359	hsa-miR-3936	CLIP-seq
MIRT2563360	hsa-miR-4295	CLIP-seq
MIRT2563361	hsa-miR-4311	CLIP-seq
MIRT2563362	hsa-miR-454	CLIP-seq
MIRT2563363	hsa-miR-4677-3p	CLIP-seq
MIRT2563364	hsa-miR-4708-3p	CLIP-seq
MIRT2563365	hsa-miR-4726-3p	CLIP-seq
MIRT2563366	hsa-miR-4731-5p	CLIP-seq
MIRT2563367	hsa-miR-548u	CLIP-seq
MIRT2563368	hsa-miR-580	CLIP-seq
MIRT2563369	hsa-miR-665	CLIP-seq
MIRT2563345	hsa-miR-1252	CLIP-seq
MIRT2563346	hsa-miR-130a	CLIP-seq
MIRT2563347	hsa-miR-130b	CLIP-seq
MIRT2563348	hsa-miR-148a	CLIP-seq
MIRT2563349	hsa-miR-148b	CLIP-seq
MIRT2563350	hsa-miR-152	CLIP-seq
MIRT2033800	hsa-miR-1915	CLIP-seq
MIRT2563351	hsa-miR-2861	CLIP-seq
MIRT2563352	hsa-miR-301a	CLIP-seq
MIRT2563353	hsa-miR-301b	CLIP-seq
MIRT2563354	hsa-miR-3136-3p	CLIP-seq
MIRT2563356	hsa-miR-3150a-5p	CLIP-seq
MIRT2563357	hsa-miR-3150b-5p	CLIP-seq
MIRT2264217	hsa-miR-3185	CLIP-seq
MIRT2563358	hsa-miR-3666	CLIP-seq
MIRT2033803	hsa-miR-3922-5p	CLIP-seq
MIRT2563359	hsa-miR-3936	CLIP-seq
MIRT2563360	hsa-miR-4295	CLIP-seq
MIRT2563362	hsa-miR-454	CLIP-seq
MIRT2563363	hsa-miR-4677-3p	CLIP-seq
MIRT2563364	hsa-miR-4708-3p	CLIP-seq
MIRT2563365	hsa-miR-4726-3p	CLIP-seq
MIRT2563366	hsa-miR-4731-5p	CLIP-seq
MIRT2563367	hsa-miR-548u	CLIP-seq
MIRT2563368	hsa-miR-580	CLIP-seq
MIRT2563369	hsa-miR-665	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016567	Process	Protein ubiquitination	IEA
GO:0042802	Function	Identical protein binding	IEA

MIM	HGNC	e!Ensembl
618753	16917	ENSG00000132128

Protein

UniProt ID

Q15345

Protein name

Leucine-rich repeat-containing protein 41 (Protein Muf1)

Protein function

Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Family and domains

Sequence

MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPNAPPALFELCGRAVSAHMGV
LESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLES
VTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELV
AEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPES
ALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAA
LMASRRKSEAKQMPRAAPATRVTRRSTQESLTAGGTDLKRELHPPATSHEAPGTKRSPSA
PAATSSASSSTSSYKRAPASSAPQPKPLKRFKRAAGKKGARTRQGPGAESEDLYDFVFIV
AGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTL
CHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSGQAGCRLRALHLSDLFSPLPILELT
RAIVRALPLLRVLSIRVDHPSQRDNPGVPGNAGPPSHIIGDEEIPENCLEQLEMGFPRGA
QPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLALKRLSFHDMNLADCQ
SEVLFLLQNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLL
ALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVT
AREAIRRLRATCHVVSDSWDSSQAFADYVSTM

Sequence length

812

Interactions

View interactions

	Reactome
			Neddylation Antigen processing: Ubiquitination & Proteasome degradation

LRRC41 (leucine rich repeat containing 41)