Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10489
Gene name Gene Name - the full gene name approved by the HGNC.	Leucine rich repeat containing 41
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LRRC41
Synonyms (NCBI Gene) Gene synonyms aliases	MUF1, PP7759
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p34.1-p33

Show/Hide all(91)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016965	hsa-miR-335-5p	Microarray	18185580
MIRT052252	hsa-let-7b-5p	CLASH	23622248
MIRT051581	hsa-let-7e-5p	CLASH	23622248
MIRT050707	hsa-miR-18a-5p	CLASH	23622248
MIRT048516	hsa-miR-100-5p	CLASH	23622248
MIRT048205	hsa-miR-196a-5p	CLASH	23622248
MIRT046461	hsa-miR-15b-5p	CLASH	23622248
MIRT045506	hsa-miR-149-5p	CLASH	23622248
MIRT040052	hsa-miR-615-3p	CLASH	23622248
MIRT038887	hsa-miR-93-3p	CLASH	23622248
MIRT536223	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT536222	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT536221	hsa-miR-548m	PAR-CLIP	22012620
MIRT536220	hsa-miR-6507-5p	PAR-CLIP	22012620
MIRT536219	hsa-miR-5681a	PAR-CLIP	22012620
MIRT536218	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT536223	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT536222	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT536221	hsa-miR-548m	PAR-CLIP	22012620
MIRT536220	hsa-miR-6507-5p	PAR-CLIP	22012620
MIRT536219	hsa-miR-5681a	PAR-CLIP	22012620
MIRT536218	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT2033800	hsa-miR-1915	CLIP-seq
MIRT2033801	hsa-miR-3714	CLIP-seq
MIRT2033802	hsa-miR-3914	CLIP-seq
MIRT2033803	hsa-miR-3922-5p	CLIP-seq
MIRT2033804	hsa-miR-4690-3p	CLIP-seq
MIRT2033805	hsa-miR-4747-5p	CLIP-seq
MIRT2033806	hsa-miR-4779	CLIP-seq
MIRT2033807	hsa-miR-873	CLIP-seq
MIRT2033808	hsa-miR-940	CLIP-seq
MIRT2264216	hsa-miR-214	CLIP-seq
MIRT2264217	hsa-miR-3185	CLIP-seq
MIRT2264218	hsa-miR-3619-5p	CLIP-seq
MIRT2264219	hsa-miR-4530	CLIP-seq
MIRT2264220	hsa-miR-761	CLIP-seq
MIRT2033804	hsa-miR-4690-3p	CLIP-seq
MIRT2563345	hsa-miR-1252	CLIP-seq
MIRT2563346	hsa-miR-130a	CLIP-seq
MIRT2563347	hsa-miR-130b	CLIP-seq
MIRT2563348	hsa-miR-148a	CLIP-seq
MIRT2563349	hsa-miR-148b	CLIP-seq
MIRT2563350	hsa-miR-152	CLIP-seq
MIRT2033800	hsa-miR-1915	CLIP-seq
MIRT2563351	hsa-miR-2861	CLIP-seq
MIRT2563352	hsa-miR-301a	CLIP-seq
MIRT2563353	hsa-miR-301b	CLIP-seq
MIRT2563354	hsa-miR-3136-3p	CLIP-seq
MIRT2563355	hsa-miR-3148	CLIP-seq
MIRT2563356	hsa-miR-3150a-5p	CLIP-seq
MIRT2563357	hsa-miR-3150b-5p	CLIP-seq
MIRT2264217	hsa-miR-3185	CLIP-seq
MIRT2563358	hsa-miR-3666	CLIP-seq
MIRT2033803	hsa-miR-3922-5p	CLIP-seq
MIRT2563359	hsa-miR-3936	CLIP-seq
MIRT2563360	hsa-miR-4295	CLIP-seq
MIRT2563361	hsa-miR-4311	CLIP-seq
MIRT2563362	hsa-miR-454	CLIP-seq
MIRT2563363	hsa-miR-4677-3p	CLIP-seq
MIRT2563364	hsa-miR-4708-3p	CLIP-seq
MIRT2563365	hsa-miR-4726-3p	CLIP-seq
MIRT2563366	hsa-miR-4731-5p	CLIP-seq
MIRT2563367	hsa-miR-548u	CLIP-seq
MIRT2563368	hsa-miR-580	CLIP-seq
MIRT2563369	hsa-miR-665	CLIP-seq
MIRT2563345	hsa-miR-1252	CLIP-seq
MIRT2563346	hsa-miR-130a	CLIP-seq
MIRT2563347	hsa-miR-130b	CLIP-seq
MIRT2563348	hsa-miR-148a	CLIP-seq
MIRT2563349	hsa-miR-148b	CLIP-seq
MIRT2563350	hsa-miR-152	CLIP-seq
MIRT2033800	hsa-miR-1915	CLIP-seq
MIRT2563351	hsa-miR-2861	CLIP-seq
MIRT2563352	hsa-miR-301a	CLIP-seq
MIRT2563353	hsa-miR-301b	CLIP-seq
MIRT2563354	hsa-miR-3136-3p	CLIP-seq
MIRT2563356	hsa-miR-3150a-5p	CLIP-seq
MIRT2563357	hsa-miR-3150b-5p	CLIP-seq
MIRT2264217	hsa-miR-3185	CLIP-seq
MIRT2563358	hsa-miR-3666	CLIP-seq
MIRT2033803	hsa-miR-3922-5p	CLIP-seq
MIRT2563359	hsa-miR-3936	CLIP-seq
MIRT2563360	hsa-miR-4295	CLIP-seq
MIRT2563362	hsa-miR-454	CLIP-seq
MIRT2563363	hsa-miR-4677-3p	CLIP-seq
MIRT2563364	hsa-miR-4708-3p	CLIP-seq
MIRT2563365	hsa-miR-4726-3p	CLIP-seq
MIRT2563366	hsa-miR-4731-5p	CLIP-seq
MIRT2563367	hsa-miR-548u	CLIP-seq
MIRT2563368	hsa-miR-580	CLIP-seq
MIRT2563369	hsa-miR-665	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005829	Component	Cytosol	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016567	Process	Protein ubiquitination	IEA
GO:0043687	Process	Post-translational protein modification	TAS

MIM	HGNC	e!Ensembl
618753	16917	ENSG00000132128

Protein

UniProt ID

Q15345

Protein name

Leucine-rich repeat-containing protein 41 (Protein Muf1)

Protein function

Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Family and domains

Sequence

MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPNAPPALFELCGRAVSAHMGV
LESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLES
VTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELV
AEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPES
ALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAA
LMASRRKSEAKQMPRAAPATRVTRRSTQESLTAGGTDLKRELHPPATSHEAPGTKRSPSA
PAATSSASSSTSSYKRAPASSAPQPKPLKRFKRAAGKKGARTRQGPGAESEDLYDFVFIV
AGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTL
CHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSGQAGCRLRALHLSDLFSPLPILELT
RAIVRALPLLRVLSIRVDHPSQRDNPGVPGNAGPPSHIIGDEEIPENCLEQLEMGFPRGA
QPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLALKRLSFHDMNLADCQ
SEVLFLLQNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLL
ALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVT
AREAIRRLRATCHVVSDSWDSSQAFADYVSTM

Sequence length

812

Interactions

View interactions

	Reactome
			Neddylation Antigen processing: Ubiquitination & Proteasome degradation

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID
Causal
Breast carcinoma	Ductal Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)
Lymphoma	Lymphoma, Non-Hodgkin, Familial	rs11540652, rs1592119138, rs1592123162, rs1599367044

LRRC41 (leucine rich repeat containing 41)