Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10478
Gene name	Solute carrier family 25 member 17
Gene symbol	SLC25A17
Synonyms (NCBI Gene)	PMP34
Chromosome	22
Chromosome location	22q13.2
Summary	This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants. [provided by Ref

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miRTarBase ID	miRNA	Experiments	Reference
MIRT048223	hsa-miR-196a-5p	CLASH	23622248
MIRT643548	hsa-miR-4496	HITS-CLIP	23824327
MIRT643547	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT643546	hsa-miR-4459	HITS-CLIP	23824327
MIRT643545	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT643544	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT643543	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT643542	hsa-miR-4469	HITS-CLIP	23824327
MIRT643541	hsa-miR-766-5p	HITS-CLIP	23824327
MIRT643540	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT643539	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT643548	hsa-miR-4496	HITS-CLIP	23824327
MIRT643547	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT643546	hsa-miR-4459	HITS-CLIP	23824327
MIRT643545	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT643544	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT643543	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT643542	hsa-miR-4469	HITS-CLIP	23824327
MIRT643541	hsa-miR-766-5p	HITS-CLIP	23824327
MIRT643540	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT643539	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT643548	hsa-miR-4496	HITS-CLIP	23824327
MIRT643547	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT643546	hsa-miR-4459	HITS-CLIP	23824327
MIRT643545	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT643544	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT643543	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT643542	hsa-miR-4469	HITS-CLIP	23824327
MIRT643541	hsa-miR-766-5p	HITS-CLIP	23824327
MIRT643540	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT643539	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT643548	hsa-miR-4496	HITS-CLIP	23824327
MIRT643547	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT643546	hsa-miR-4459	HITS-CLIP	23824327
MIRT643545	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT643544	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT643543	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT643542	hsa-miR-4469	HITS-CLIP	23824327
MIRT643541	hsa-miR-766-5p	HITS-CLIP	23824327
MIRT643540	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT643539	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT1355523	hsa-miR-1236	CLIP-seq
MIRT1355524	hsa-miR-1297	CLIP-seq
MIRT1355525	hsa-miR-1302	CLIP-seq
MIRT1355526	hsa-miR-1323	CLIP-seq
MIRT1355527	hsa-miR-23a	CLIP-seq
MIRT1355528	hsa-miR-23b	CLIP-seq
MIRT1355529	hsa-miR-23c	CLIP-seq
MIRT1355530	hsa-miR-26a	CLIP-seq
MIRT1355531	hsa-miR-26b	CLIP-seq
MIRT1355532	hsa-miR-2964a-5p	CLIP-seq
MIRT1355533	hsa-miR-3122	CLIP-seq
MIRT1355534	hsa-miR-3136-5p	CLIP-seq
MIRT1355535	hsa-miR-3158-3p	CLIP-seq
MIRT1355536	hsa-miR-3199	CLIP-seq
MIRT1355537	hsa-miR-34b	CLIP-seq
MIRT1355538	hsa-miR-3664-3p	CLIP-seq
MIRT1355539	hsa-miR-3669	CLIP-seq
MIRT1355540	hsa-miR-3908	CLIP-seq
MIRT1355541	hsa-miR-3913-5p	CLIP-seq
MIRT1355542	hsa-miR-412	CLIP-seq
MIRT1355543	hsa-miR-4291	CLIP-seq
MIRT1355544	hsa-miR-4298	CLIP-seq
MIRT1355545	hsa-miR-4307	CLIP-seq
MIRT1355546	hsa-miR-4433	CLIP-seq
MIRT1355547	hsa-miR-4439	CLIP-seq
MIRT1355548	hsa-miR-4464	CLIP-seq
MIRT1355549	hsa-miR-4465	CLIP-seq
MIRT1355550	hsa-miR-4513	CLIP-seq
MIRT1355551	hsa-miR-4540	CLIP-seq
MIRT1355552	hsa-miR-4685-5p	CLIP-seq
MIRT1355553	hsa-miR-4712-3p	CLIP-seq
MIRT1355554	hsa-miR-4729	CLIP-seq
MIRT1355555	hsa-miR-4748	CLIP-seq
MIRT1355556	hsa-miR-4753-3p	CLIP-seq
MIRT1355557	hsa-miR-4796-5p	CLIP-seq
MIRT1355558	hsa-miR-5096	CLIP-seq
MIRT1355559	hsa-miR-510	CLIP-seq
MIRT1355560	hsa-miR-526b	CLIP-seq
MIRT1355561	hsa-miR-545	CLIP-seq
MIRT1355562	hsa-miR-548c-3p	CLIP-seq
MIRT1355563	hsa-miR-548o	CLIP-seq
MIRT1355564	hsa-miR-548p	CLIP-seq
MIRT1355565	hsa-miR-579	CLIP-seq
MIRT1355566	hsa-miR-591	CLIP-seq
MIRT1355567	hsa-miR-642a	CLIP-seq
MIRT1355568	hsa-miR-942	CLIP-seq
MIRT1355569	hsa-miR-943	CLIP-seq
MIRT2105292	hsa-miR-1207-5p	CLIP-seq
MIRT2105293	hsa-miR-1305	CLIP-seq
MIRT2105294	hsa-miR-3140-3p	CLIP-seq
MIRT2105295	hsa-miR-4700-3p	CLIP-seq
MIRT2105296	hsa-miR-4722-5p	CLIP-seq
MIRT2105297	hsa-miR-4736	CLIP-seq
MIRT2105298	hsa-miR-4763-3p	CLIP-seq
MIRT2105299	hsa-miR-498	CLIP-seq
MIRT1355523	hsa-miR-1236	CLIP-seq
MIRT2329872	hsa-miR-141	CLIP-seq
MIRT2329873	hsa-miR-200a	CLIP-seq
MIRT2329874	hsa-miR-338-3p	CLIP-seq
MIRT1355537	hsa-miR-34b	CLIP-seq
MIRT2329875	hsa-miR-3591-3p	CLIP-seq
MIRT1355538	hsa-miR-3664-3p	CLIP-seq
MIRT1355542	hsa-miR-412	CLIP-seq
MIRT2329876	hsa-miR-4329	CLIP-seq
MIRT1355546	hsa-miR-4433	CLIP-seq
MIRT2329877	hsa-miR-4668-3p	CLIP-seq
MIRT2329878	hsa-miR-4715-3p	CLIP-seq
MIRT2329879	hsa-miR-4715-5p	CLIP-seq
MIRT1355556	hsa-miR-4753-3p	CLIP-seq
MIRT1355559	hsa-miR-510	CLIP-seq
MIRT1355568	hsa-miR-942	CLIP-seq
MIRT2624017	hsa-miR-1207-3p	CLIP-seq
MIRT2105292	hsa-miR-1207-5p	CLIP-seq
MIRT2624018	hsa-miR-1224-5p	CLIP-seq
MIRT1355523	hsa-miR-1236	CLIP-seq
MIRT2624019	hsa-miR-1275	CLIP-seq
MIRT2624020	hsa-miR-1304	CLIP-seq
MIRT2105293	hsa-miR-1305	CLIP-seq
MIRT2624021	hsa-miR-145	CLIP-seq
MIRT2624022	hsa-miR-18a	CLIP-seq
MIRT2624023	hsa-miR-18b	CLIP-seq
MIRT2624024	hsa-miR-1914	CLIP-seq
MIRT2624025	hsa-miR-2355-3p	CLIP-seq
MIRT1355527	hsa-miR-23a	CLIP-seq
MIRT1355528	hsa-miR-23b	CLIP-seq
MIRT1355529	hsa-miR-23c	CLIP-seq
MIRT2624026	hsa-miR-3121-3p	CLIP-seq
MIRT2624027	hsa-miR-3127-5p	CLIP-seq
MIRT2105294	hsa-miR-3140-3p	CLIP-seq
MIRT2624028	hsa-miR-3143	CLIP-seq
MIRT2624029	hsa-miR-3150b-3p	CLIP-seq
MIRT2624030	hsa-miR-3153	CLIP-seq
MIRT2624031	hsa-miR-3175	CLIP-seq
MIRT2624032	hsa-miR-3187-3p	CLIP-seq
MIRT2624033	hsa-miR-323-3p	CLIP-seq
MIRT2329874	hsa-miR-338-3p	CLIP-seq
MIRT2624034	hsa-miR-339-5p	CLIP-seq
MIRT1355537	hsa-miR-34b	CLIP-seq
MIRT2624035	hsa-miR-3653	CLIP-seq
MIRT2624036	hsa-miR-3658	CLIP-seq
MIRT1355538	hsa-miR-3664-3p	CLIP-seq
MIRT1355540	hsa-miR-3908	CLIP-seq
MIRT2624037	hsa-miR-3915	CLIP-seq
MIRT2624038	hsa-miR-3925-5p	CLIP-seq
MIRT2624039	hsa-miR-3941	CLIP-seq
MIRT1355542	hsa-miR-412	CLIP-seq
MIRT2624040	hsa-miR-4270	CLIP-seq
MIRT1355543	hsa-miR-4291	CLIP-seq
MIRT1355545	hsa-miR-4307	CLIP-seq
MIRT2624041	hsa-miR-4311	CLIP-seq
MIRT1355546	hsa-miR-4433	CLIP-seq
MIRT2624042	hsa-miR-4435	CLIP-seq
MIRT2624043	hsa-miR-4441	CLIP-seq
MIRT1355548	hsa-miR-4464	CLIP-seq
MIRT2624044	hsa-miR-4477a	CLIP-seq
MIRT2624045	hsa-miR-4504	CLIP-seq
MIRT2624046	hsa-miR-4525	CLIP-seq
MIRT2624047	hsa-miR-4529-5p	CLIP-seq
MIRT2624048	hsa-miR-4643	CLIP-seq
MIRT2624049	hsa-miR-4646-3p	CLIP-seq
MIRT2624050	hsa-miR-466	CLIP-seq
MIRT2624051	hsa-miR-4665-5p	CLIP-seq
MIRT2624052	hsa-miR-4666-5p	CLIP-seq
MIRT2329877	hsa-miR-4668-3p	CLIP-seq
MIRT2624053	hsa-miR-4672	CLIP-seq
MIRT2624054	hsa-miR-4689	CLIP-seq
MIRT2624055	hsa-miR-4701-5p	CLIP-seq
MIRT1355553	hsa-miR-4712-3p	CLIP-seq
MIRT2329878	hsa-miR-4715-3p	CLIP-seq
MIRT2329879	hsa-miR-4715-5p	CLIP-seq
MIRT2624056	hsa-miR-4719	CLIP-seq
MIRT2105296	hsa-miR-4722-5p	CLIP-seq
MIRT2624057	hsa-miR-4723-5p	CLIP-seq
MIRT2624058	hsa-miR-4735-3p	CLIP-seq
MIRT2105297	hsa-miR-4736	CLIP-seq
MIRT1355555	hsa-miR-4748	CLIP-seq
MIRT1355556	hsa-miR-4753-3p	CLIP-seq
MIRT2105298	hsa-miR-4763-3p	CLIP-seq
MIRT2624059	hsa-miR-4773	CLIP-seq
MIRT2624060	hsa-miR-4774-5p	CLIP-seq
MIRT2624061	hsa-miR-4784	CLIP-seq
MIRT2624062	hsa-miR-4789-3p	CLIP-seq
MIRT2624063	hsa-miR-490-3p	CLIP-seq
MIRT2105299	hsa-miR-498	CLIP-seq
MIRT1355558	hsa-miR-5096	CLIP-seq
MIRT1355559	hsa-miR-510	CLIP-seq
MIRT2624064	hsa-miR-513a-3p	CLIP-seq
MIRT2624065	hsa-miR-543	CLIP-seq
MIRT1355561	hsa-miR-545	CLIP-seq
MIRT2624066	hsa-miR-548l	CLIP-seq
MIRT2624067	hsa-miR-548n	CLIP-seq
MIRT2624068	hsa-miR-548s	CLIP-seq
MIRT2624069	hsa-miR-549	CLIP-seq
MIRT2624070	hsa-miR-570	CLIP-seq
MIRT1355565	hsa-miR-579	CLIP-seq
MIRT2624071	hsa-miR-588	CLIP-seq
MIRT2624072	hsa-miR-625	CLIP-seq
MIRT2624073	hsa-miR-637	CLIP-seq
MIRT1355567	hsa-miR-642a	CLIP-seq
MIRT2624074	hsa-miR-676	CLIP-seq
MIRT1355568	hsa-miR-942	CLIP-seq
MIRT2624017	hsa-miR-1207-3p	CLIP-seq
MIRT2105292	hsa-miR-1207-5p	CLIP-seq
MIRT2624018	hsa-miR-1224-5p	CLIP-seq
MIRT2624019	hsa-miR-1275	CLIP-seq
MIRT2624020	hsa-miR-1304	CLIP-seq
MIRT2105293	hsa-miR-1305	CLIP-seq
MIRT2624021	hsa-miR-145	CLIP-seq
MIRT2624022	hsa-miR-18a	CLIP-seq
MIRT2624023	hsa-miR-18b	CLIP-seq
MIRT2624024	hsa-miR-1914	CLIP-seq
MIRT2624025	hsa-miR-2355-3p	CLIP-seq
MIRT2624026	hsa-miR-3121-3p	CLIP-seq
MIRT2624027	hsa-miR-3127-5p	CLIP-seq
MIRT2105294	hsa-miR-3140-3p	CLIP-seq
MIRT2624028	hsa-miR-3143	CLIP-seq
MIRT2624029	hsa-miR-3150b-3p	CLIP-seq
MIRT2624030	hsa-miR-3153	CLIP-seq
MIRT2624031	hsa-miR-3175	CLIP-seq
MIRT2624032	hsa-miR-3187-3p	CLIP-seq
MIRT2329874	hsa-miR-338-3p	CLIP-seq
MIRT2624034	hsa-miR-339-5p	CLIP-seq
MIRT1355537	hsa-miR-34b	CLIP-seq
MIRT2624035	hsa-miR-3653	CLIP-seq
MIRT2624036	hsa-miR-3658	CLIP-seq
MIRT1355540	hsa-miR-3908	CLIP-seq
MIRT2624037	hsa-miR-3915	CLIP-seq
MIRT2624038	hsa-miR-3925-5p	CLIP-seq
MIRT2624040	hsa-miR-4270	CLIP-seq
MIRT1355543	hsa-miR-4291	CLIP-seq
MIRT1355545	hsa-miR-4307	CLIP-seq
MIRT2624041	hsa-miR-4311	CLIP-seq
MIRT2624042	hsa-miR-4435	CLIP-seq
MIRT2624043	hsa-miR-4441	CLIP-seq
MIRT1355548	hsa-miR-4464	CLIP-seq
MIRT2624044	hsa-miR-4477a	CLIP-seq
MIRT2624045	hsa-miR-4504	CLIP-seq
MIRT2624046	hsa-miR-4525	CLIP-seq
MIRT2624047	hsa-miR-4529-5p	CLIP-seq
MIRT2624049	hsa-miR-4646-3p	CLIP-seq
MIRT2624051	hsa-miR-4665-5p	CLIP-seq
MIRT2624052	hsa-miR-4666-5p	CLIP-seq
MIRT2329877	hsa-miR-4668-3p	CLIP-seq
MIRT2624054	hsa-miR-4689	CLIP-seq
MIRT2624055	hsa-miR-4701-5p	CLIP-seq
MIRT2329878	hsa-miR-4715-3p	CLIP-seq
MIRT2329879	hsa-miR-4715-5p	CLIP-seq
MIRT2105296	hsa-miR-4722-5p	CLIP-seq
MIRT2624057	hsa-miR-4723-5p	CLIP-seq
MIRT2624058	hsa-miR-4735-3p	CLIP-seq
MIRT2105297	hsa-miR-4736	CLIP-seq
MIRT1355555	hsa-miR-4748	CLIP-seq
MIRT2105298	hsa-miR-4763-3p	CLIP-seq
MIRT2624059	hsa-miR-4773	CLIP-seq
MIRT2624060	hsa-miR-4774-5p	CLIP-seq
MIRT2624061	hsa-miR-4784	CLIP-seq
MIRT2624063	hsa-miR-490-3p	CLIP-seq
MIRT2105299	hsa-miR-498	CLIP-seq
MIRT1355558	hsa-miR-5096	CLIP-seq
MIRT2624064	hsa-miR-513a-3p	CLIP-seq
MIRT2624065	hsa-miR-543	CLIP-seq
MIRT1355561	hsa-miR-545	CLIP-seq
MIRT2624066	hsa-miR-548l	CLIP-seq
MIRT2624067	hsa-miR-548n	CLIP-seq
MIRT2624068	hsa-miR-548s	CLIP-seq
MIRT2624069	hsa-miR-549	CLIP-seq
MIRT2624070	hsa-miR-570	CLIP-seq
MIRT1355565	hsa-miR-579	CLIP-seq
MIRT2624071	hsa-miR-588	CLIP-seq
MIRT2624072	hsa-miR-625	CLIP-seq
MIRT2624073	hsa-miR-637	CLIP-seq
MIRT2624074	hsa-miR-676	CLIP-seq

Show/Hide all (39)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000295	Function	Adenine nucleotide transmembrane transporter activity	TAS
GO:0001561	Process	Fatty acid alpha-oxidation	TAS
GO:0005347	Function	ATP transmembrane transporter activity	IBA
GO:0005347	Function	ATP transmembrane transporter activity	IGI	12445829
GO:0005515	Function	Protein binding	IPI	10704444, 11402059, 14709540, 32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005777	Component	Peroxisome	IDA	9874197
GO:0005777	Component	Peroxisome	IEA
GO:0005778	Component	Peroxisomal membrane	IBA
GO:0005778	Component	Peroxisomal membrane	IDA	11121399, 11402059, 14709540, 21153762
GO:0005778	Component	Peroxisomal membrane	IEA
GO:0005778	Component	Peroxisomal membrane	TAS
GO:0005829	Component	Cytosol	TAS
GO:0006635	Process	Fatty acid beta-oxidation	IGI	12445829
GO:0015217	Function	ADP transmembrane transporter activity	IBA
GO:0015217	Function	ADP transmembrane transporter activity	IDA	22185573
GO:0015228	Function	Coenzyme A transmembrane transporter activity	IBA
GO:0015228	Function	Coenzyme A transmembrane transporter activity	IDA	22185573
GO:0015230	Function	FAD transmembrane transporter activity	IBA
GO:0015230	Function	FAD transmembrane transporter activity	IDA	22185573
GO:0015297	Function	Antiporter activity	IEA
GO:0015866	Process	ADP transport	IEA
GO:0015867	Process	ATP transport	IGI	12445829
GO:0015908	Process	Fatty acid transport	IGI	12445829
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0035349	Process	Coenzyme A transmembrane transport	IEA
GO:0035350	Process	FAD transmembrane transport	IEA
GO:0035352	Process	NAD transmembrane transport	IEA
GO:0044610	Function	FMN transmembrane transporter activity	IBA
GO:0044610	Function	FMN transmembrane transporter activity	IDA	22185573
GO:0051087	Function	Protein-folding chaperone binding	IPI	11402059
GO:0051724	Function	NAD transmembrane transporter activity	IBA
GO:0051724	Function	NAD transmembrane transporter activity	IDA	22185573
GO:0055085	Process	Transmembrane transport	IEA
GO:0080121	Process	AMP transport	IEA
GO:0080122	Function	AMP transmembrane transporter activity	IBA
GO:0080122	Function	AMP transmembrane transporter activity	IDA	22185573
GO:1901679	Process	Nucleotide transmembrane transport	IDA	22185573

MIM	HGNC	e!Ensembl
606795	10987	ENSG00000100372

O43808

Protein name

Peroxisomal membrane protein PMP34 (34 kDa peroxisomal membrane protein) (Solute carrier family 25 member 17)

Protein function

Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extent for nicotinamide adenine dinucleotide (NAD(

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00153	Mito_carr	6 → 97	Mitochondrial carrier protein	Family
PF00153	Mito_carr	97 → 197	Mitochondrial carrier protein	Family
PF00153	Mito_carr	199 → 297	Mitochondrial carrier protein	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Expressed in liver. {ECO:0000269|PubMed:22185573, ECO:0000269|PubMed:9874197}.

Sequence

MASVLSYESLVHAVAGAVGSVTAMTVFFPLDTARLRLQVDEKRKSKTTHMVLLEIIKEEG
LLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHSTTGKDLVVGFVAGVVNVLLTT
PLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPA
IQFMFYEGLKRQLLKKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPE
NRTLGSLRNILYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMG
LKRAHQH

Sequence length

307

Interactions

View interactions

	KEGG		Reactome
	Peroxisome		Alpha-oxidation of phytanate Class I peroxisomal membrane protein import

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Uveal melanoma	Uncertain significance	rs144758492	RCV005931026

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Lymphatic Metastasis	Associate	37386359
Neoplasms	Associate	37386359
Squamous Cell Carcinoma of Head and Neck	Associate	37386359

SLC25A17 (solute carrier family 25 member 17)