CDS1 (CDP-diacylglycerol synthase 1)

Gene

• Entrez ID: 1040
• Gene name: CDP-diacylglycerol synthase 1
• Gene symbol: CDS1
• Synonyms (NCBI Gene): CDS 1
• Chromosome: 4
• Chromosome location: 4q21.23
• Summary: Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzy

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019089	hsa-miR-335-5p	Microarray	18185580
MIRT043107	hsa-miR-324-5p	CLASH	23622248
MIRT437688	hsa-miR-223-3p	Microarray, qRT-PCR	22815788
MIRT882270	hsa-miR-1237	CLIP-seq
MIRT882271	hsa-miR-124	CLIP-seq
MIRT882272	hsa-miR-1248	CLIP-seq
MIRT882273	hsa-miR-1252	CLIP-seq
MIRT882274	hsa-miR-1269	CLIP-seq
MIRT882275	hsa-miR-1269b	CLIP-seq
MIRT882276	hsa-miR-1271	CLIP-seq
MIRT882277	hsa-miR-128	CLIP-seq
MIRT882278	hsa-miR-1286	CLIP-seq
MIRT882279	hsa-miR-1288	CLIP-seq
MIRT882280	hsa-miR-1297	CLIP-seq
MIRT882281	hsa-miR-130a	CLIP-seq
MIRT882282	hsa-miR-130b	CLIP-seq
MIRT882283	hsa-miR-135a	CLIP-seq
MIRT882284	hsa-miR-135b	CLIP-seq
MIRT882285	hsa-miR-146a	CLIP-seq
MIRT882286	hsa-miR-146b-5p	CLIP-seq
MIRT882287	hsa-miR-1470	CLIP-seq
MIRT882288	hsa-miR-153	CLIP-seq
MIRT882289	hsa-miR-15a	CLIP-seq
MIRT882290	hsa-miR-15b	CLIP-seq
MIRT882291	hsa-miR-16	CLIP-seq
MIRT882292	hsa-miR-182	CLIP-seq
MIRT882293	hsa-miR-185	CLIP-seq
MIRT882294	hsa-miR-1910	CLIP-seq
MIRT882295	hsa-miR-192	CLIP-seq
MIRT882296	hsa-miR-195	CLIP-seq
MIRT882297	hsa-miR-197	CLIP-seq
MIRT882298	hsa-miR-198	CLIP-seq
MIRT882299	hsa-miR-19a	CLIP-seq
MIRT882300	hsa-miR-19b	CLIP-seq
MIRT882301	hsa-miR-2053	CLIP-seq
MIRT882302	hsa-miR-21	CLIP-seq
MIRT882303	hsa-miR-2113	CLIP-seq
MIRT882304	hsa-miR-215	CLIP-seq
MIRT882305	hsa-miR-223	CLIP-seq
MIRT882306	hsa-miR-25	CLIP-seq
MIRT882307	hsa-miR-2681	CLIP-seq
MIRT882308	hsa-miR-26a	CLIP-seq
MIRT882309	hsa-miR-26b	CLIP-seq
MIRT882310	hsa-miR-27a	CLIP-seq
MIRT882311	hsa-miR-27b	CLIP-seq
MIRT882312	hsa-miR-301a	CLIP-seq
MIRT882313	hsa-miR-301b	CLIP-seq
MIRT882314	hsa-miR-3140-5p	CLIP-seq
MIRT882315	hsa-miR-3150b-3p	CLIP-seq
MIRT882316	hsa-miR-3155	CLIP-seq
MIRT882317	hsa-miR-3155b	CLIP-seq
MIRT882318	hsa-miR-3163	CLIP-seq
MIRT882319	hsa-miR-32	CLIP-seq
MIRT882320	hsa-miR-320a	CLIP-seq
MIRT882321	hsa-miR-320b	CLIP-seq
MIRT882322	hsa-miR-320c	CLIP-seq
MIRT882323	hsa-miR-320d	CLIP-seq
MIRT882324	hsa-miR-320e	CLIP-seq
MIRT882325	hsa-miR-331-3p	CLIP-seq
MIRT882326	hsa-miR-337-3p	CLIP-seq
MIRT882327	hsa-miR-338-5p	CLIP-seq
MIRT882328	hsa-miR-33a	CLIP-seq
MIRT882329	hsa-miR-33b	CLIP-seq
MIRT882330	hsa-miR-340	CLIP-seq
MIRT882331	hsa-miR-3591-5p	CLIP-seq
MIRT882332	hsa-miR-3613-3p	CLIP-seq
MIRT882333	hsa-miR-363	CLIP-seq
MIRT882334	hsa-miR-3655	CLIP-seq
MIRT882335	hsa-miR-3666	CLIP-seq
MIRT882336	hsa-miR-3667-3p	CLIP-seq
MIRT882337	hsa-miR-367	CLIP-seq
MIRT882338	hsa-miR-3691-3p	CLIP-seq
MIRT882339	hsa-miR-374c	CLIP-seq
MIRT882340	hsa-miR-376c	CLIP-seq
MIRT882341	hsa-miR-378	CLIP-seq
MIRT882342	hsa-miR-378b	CLIP-seq
MIRT882343	hsa-miR-378c	CLIP-seq
MIRT882344	hsa-miR-378d	CLIP-seq
MIRT882345	hsa-miR-378e	CLIP-seq
MIRT882346	hsa-miR-378f	CLIP-seq
MIRT882347	hsa-miR-378h	CLIP-seq
MIRT882348	hsa-miR-378i	CLIP-seq
MIRT882349	hsa-miR-3919	CLIP-seq
MIRT882350	hsa-miR-3925-3p	CLIP-seq
MIRT882351	hsa-miR-3936	CLIP-seq
MIRT882352	hsa-miR-3942-3p	CLIP-seq
MIRT882353	hsa-miR-422a	CLIP-seq
MIRT882354	hsa-miR-424	CLIP-seq
MIRT882355	hsa-miR-4255	CLIP-seq
MIRT882356	hsa-miR-4263	CLIP-seq
MIRT882357	hsa-miR-4271	CLIP-seq
MIRT882358	hsa-miR-4282	CLIP-seq
MIRT882359	hsa-miR-4295	CLIP-seq
MIRT882360	hsa-miR-4302	CLIP-seq
MIRT882361	hsa-miR-4306	CLIP-seq
MIRT882362	hsa-miR-4312	CLIP-seq
MIRT882363	hsa-miR-4427	CLIP-seq
MIRT882364	hsa-miR-4429	CLIP-seq
MIRT882365	hsa-miR-4464	CLIP-seq
MIRT882366	hsa-miR-4465	CLIP-seq
MIRT882367	hsa-miR-4469	CLIP-seq
MIRT882368	hsa-miR-4470	CLIP-seq
MIRT882369	hsa-miR-448	CLIP-seq
MIRT882370	hsa-miR-450b-3p	CLIP-seq
MIRT882371	hsa-miR-4514	CLIP-seq
MIRT882372	hsa-miR-4515	CLIP-seq
MIRT882373	hsa-miR-451b	CLIP-seq
MIRT882374	hsa-miR-4533	CLIP-seq
MIRT882375	hsa-miR-454	CLIP-seq
MIRT882376	hsa-miR-455-3p	CLIP-seq
MIRT882377	hsa-miR-4639-5p	CLIP-seq
MIRT882378	hsa-miR-4644	CLIP-seq
MIRT882379	hsa-miR-4645-5p	CLIP-seq
MIRT882380	hsa-miR-4660	CLIP-seq
MIRT882381	hsa-miR-4666-3p	CLIP-seq
MIRT882382	hsa-miR-4667-3p	CLIP-seq
MIRT882383	hsa-miR-4673	CLIP-seq
MIRT882384	hsa-miR-4680-3p	CLIP-seq
MIRT882385	hsa-miR-4687-3p	CLIP-seq
MIRT882386	hsa-miR-4689	CLIP-seq
MIRT882387	hsa-miR-4692	CLIP-seq
MIRT882388	hsa-miR-4697-3p	CLIP-seq
MIRT882389	hsa-miR-4713-3p	CLIP-seq
MIRT882390	hsa-miR-4714-3p	CLIP-seq
MIRT882391	hsa-miR-4722-5p	CLIP-seq
MIRT882392	hsa-miR-4725-3p	CLIP-seq
MIRT882393	hsa-miR-4740-5p	CLIP-seq
MIRT882394	hsa-miR-4747-5p	CLIP-seq
MIRT882395	hsa-miR-4748	CLIP-seq
MIRT882396	hsa-miR-4756-3p	CLIP-seq
MIRT882397	hsa-miR-4762-3p	CLIP-seq
MIRT882398	hsa-miR-4768-3p	CLIP-seq
MIRT882399	hsa-miR-4772-5p	CLIP-seq
MIRT882400	hsa-miR-4784	CLIP-seq
MIRT882401	hsa-miR-4803	CLIP-seq
MIRT882402	hsa-miR-484	CLIP-seq
MIRT882403	hsa-miR-495	CLIP-seq
MIRT882404	hsa-miR-497	CLIP-seq
MIRT882405	hsa-miR-506	CLIP-seq
MIRT882406	hsa-miR-513a-3p	CLIP-seq
MIRT882407	hsa-miR-513a-5p	CLIP-seq
MIRT882408	hsa-miR-519a	CLIP-seq
MIRT882409	hsa-miR-519b-3p	CLIP-seq
MIRT882410	hsa-miR-519c-3p	CLIP-seq
MIRT882411	hsa-miR-548a-5p	CLIP-seq
MIRT882412	hsa-miR-548ab	CLIP-seq
MIRT882413	hsa-miR-548ak	CLIP-seq
MIRT882414	hsa-miR-548an	CLIP-seq
MIRT882415	hsa-miR-548b-5p	CLIP-seq
MIRT882416	hsa-miR-548c-5p	CLIP-seq
MIRT882417	hsa-miR-548d-5p	CLIP-seq
MIRT882418	hsa-miR-548h	CLIP-seq
MIRT882419	hsa-miR-548i	CLIP-seq
MIRT882420	hsa-miR-548j	CLIP-seq
MIRT882421	hsa-miR-548n	CLIP-seq
MIRT882422	hsa-miR-548w	CLIP-seq
MIRT882423	hsa-miR-548y	CLIP-seq
MIRT882424	hsa-miR-550a	CLIP-seq
MIRT882425	hsa-miR-550b	CLIP-seq
MIRT882426	hsa-miR-559	CLIP-seq
MIRT882427	hsa-miR-576-5p	CLIP-seq
MIRT882428	hsa-miR-578	CLIP-seq
MIRT882429	hsa-miR-590-3p	CLIP-seq
MIRT882430	hsa-miR-590-5p	CLIP-seq
MIRT882431	hsa-miR-595	CLIP-seq
MIRT882432	hsa-miR-598	CLIP-seq
MIRT882433	hsa-miR-617	CLIP-seq
MIRT882434	hsa-miR-638	CLIP-seq
MIRT882435	hsa-miR-646	CLIP-seq
MIRT882436	hsa-miR-655	CLIP-seq
MIRT882437	hsa-miR-766	CLIP-seq
MIRT882438	hsa-miR-769-3p	CLIP-seq
MIRT882439	hsa-miR-92a	CLIP-seq
MIRT882440	hsa-miR-92b	CLIP-seq
MIRT882441	hsa-miR-96	CLIP-seq
MIRT1961410	hsa-miR-1184	CLIP-seq
MIRT1961411	hsa-miR-1200	CLIP-seq
MIRT882270	hsa-miR-1237	CLIP-seq
MIRT882271	hsa-miR-124	CLIP-seq
MIRT882272	hsa-miR-1248	CLIP-seq
MIRT1961412	hsa-miR-1256	CLIP-seq
MIRT1961413	hsa-miR-1267	CLIP-seq
MIRT882276	hsa-miR-1271	CLIP-seq
MIRT1961414	hsa-miR-127-5p	CLIP-seq
MIRT882277	hsa-miR-128	CLIP-seq
MIRT1961415	hsa-miR-1290	CLIP-seq
MIRT882280	hsa-miR-1297	CLIP-seq
MIRT882281	hsa-miR-130a	CLIP-seq
MIRT882282	hsa-miR-130b	CLIP-seq
MIRT882287	hsa-miR-1470	CLIP-seq
MIRT882288	hsa-miR-153	CLIP-seq
MIRT882292	hsa-miR-182	CLIP-seq
MIRT882298	hsa-miR-198	CLIP-seq
MIRT882299	hsa-miR-19a	CLIP-seq
MIRT882300	hsa-miR-19b	CLIP-seq
MIRT882301	hsa-miR-2053	CLIP-seq
MIRT1961416	hsa-miR-22	CLIP-seq
MIRT882305	hsa-miR-223	CLIP-seq
MIRT882308	hsa-miR-26a	CLIP-seq
MIRT882309	hsa-miR-26b	CLIP-seq
MIRT882310	hsa-miR-27a	CLIP-seq
MIRT882311	hsa-miR-27b	CLIP-seq
MIRT882312	hsa-miR-301a	CLIP-seq
MIRT882313	hsa-miR-301b	CLIP-seq
MIRT1961417	hsa-miR-3117-5p	CLIP-seq
MIRT882314	hsa-miR-3140-5p	CLIP-seq
MIRT1961418	hsa-miR-3146	CLIP-seq
MIRT882316	hsa-miR-3155	CLIP-seq
MIRT882317	hsa-miR-3155b	CLIP-seq
MIRT882318	hsa-miR-3163	CLIP-seq
MIRT1961419	hsa-miR-3167	CLIP-seq
MIRT882325	hsa-miR-331-3p	CLIP-seq
MIRT882326	hsa-miR-337-3p	CLIP-seq
MIRT882330	hsa-miR-340	CLIP-seq
MIRT882331	hsa-miR-3591-5p	CLIP-seq
MIRT1961420	hsa-miR-3609	CLIP-seq
MIRT882335	hsa-miR-3666	CLIP-seq
MIRT1961421	hsa-miR-3680	CLIP-seq
MIRT1961422	hsa-miR-374a	CLIP-seq
MIRT1961423	hsa-miR-374b	CLIP-seq
MIRT1961424	hsa-miR-375	CLIP-seq
MIRT882340	hsa-miR-376c	CLIP-seq
MIRT1961425	hsa-miR-3909	CLIP-seq
MIRT1961426	hsa-miR-3974	CLIP-seq
MIRT1961427	hsa-miR-412	CLIP-seq
MIRT882358	hsa-miR-4282	CLIP-seq
MIRT882359	hsa-miR-4295	CLIP-seq
MIRT882360	hsa-miR-4302	CLIP-seq
MIRT882362	hsa-miR-4312	CLIP-seq
MIRT1961428	hsa-miR-4324	CLIP-seq
MIRT882363	hsa-miR-4427	CLIP-seq
MIRT882365	hsa-miR-4464	CLIP-seq
MIRT882366	hsa-miR-4465	CLIP-seq
MIRT882367	hsa-miR-4469	CLIP-seq
MIRT882369	hsa-miR-448	CLIP-seq
MIRT1961429	hsa-miR-4517	CLIP-seq
MIRT882375	hsa-miR-454	CLIP-seq
MIRT882376	hsa-miR-455-3p	CLIP-seq
MIRT882377	hsa-miR-4639-5p	CLIP-seq
MIRT1961430	hsa-miR-4642	CLIP-seq
MIRT882382	hsa-miR-4667-3p	CLIP-seq
MIRT1961431	hsa-miR-4668-5p	CLIP-seq
MIRT882384	hsa-miR-4680-3p	CLIP-seq
MIRT1961432	hsa-miR-4691-3p	CLIP-seq
MIRT882388	hsa-miR-4697-3p	CLIP-seq
MIRT882395	hsa-miR-4748	CLIP-seq
MIRT1961433	hsa-miR-4755-3p	CLIP-seq
MIRT882397	hsa-miR-4762-3p	CLIP-seq
MIRT1961434	hsa-miR-4782-5p	CLIP-seq
MIRT882401	hsa-miR-4803	CLIP-seq
MIRT882402	hsa-miR-484	CLIP-seq
MIRT1961435	hsa-miR-502-5p	CLIP-seq
MIRT882405	hsa-miR-506	CLIP-seq
MIRT882406	hsa-miR-513a-3p	CLIP-seq
MIRT882407	hsa-miR-513a-5p	CLIP-seq
MIRT882408	hsa-miR-519a	CLIP-seq
MIRT882409	hsa-miR-519b-3p	CLIP-seq
MIRT882410	hsa-miR-519c-3p	CLIP-seq
MIRT1961436	hsa-miR-520g	CLIP-seq
MIRT1961437	hsa-miR-520h	CLIP-seq
MIRT1961438	hsa-miR-544b	CLIP-seq
MIRT1961439	hsa-miR-548ah	CLIP-seq
MIRT882414	hsa-miR-548an	CLIP-seq
MIRT1961440	hsa-miR-548l	CLIP-seq
MIRT1961441	hsa-miR-548t	CLIP-seq
MIRT882424	hsa-miR-550a	CLIP-seq
MIRT882425	hsa-miR-550b	CLIP-seq
MIRT882431	hsa-miR-595	CLIP-seq
MIRT882433	hsa-miR-617	CLIP-seq
MIRT1961442	hsa-miR-764	CLIP-seq
MIRT1961443	hsa-miR-876-5p	CLIP-seq
MIRT1961444	hsa-miR-922	CLIP-seq
MIRT882441	hsa-miR-96	CLIP-seq
MIRT882270	hsa-miR-1237	CLIP-seq
MIRT882272	hsa-miR-1248	CLIP-seq
MIRT882277	hsa-miR-128	CLIP-seq
MIRT882281	hsa-miR-130a	CLIP-seq
MIRT882282	hsa-miR-130b	CLIP-seq
MIRT2198110	hsa-miR-148a	CLIP-seq
MIRT2198111	hsa-miR-148b	CLIP-seq
MIRT2198112	hsa-miR-152	CLIP-seq
MIRT882289	hsa-miR-15a	CLIP-seq
MIRT882290	hsa-miR-15b	CLIP-seq
MIRT882291	hsa-miR-16	CLIP-seq
MIRT2198113	hsa-miR-183	CLIP-seq
MIRT882296	hsa-miR-195	CLIP-seq
MIRT882299	hsa-miR-19a	CLIP-seq
MIRT882300	hsa-miR-19b	CLIP-seq
MIRT882301	hsa-miR-2053	CLIP-seq
MIRT882302	hsa-miR-21	CLIP-seq
MIRT2198114	hsa-miR-2116	CLIP-seq
MIRT2198115	hsa-miR-217	CLIP-seq
MIRT2198116	hsa-miR-2278	CLIP-seq
MIRT882310	hsa-miR-27a	CLIP-seq
MIRT882311	hsa-miR-27b	CLIP-seq
MIRT882312	hsa-miR-301a	CLIP-seq
MIRT882313	hsa-miR-301b	CLIP-seq
MIRT2198117	hsa-miR-337-5p	CLIP-seq
MIRT882331	hsa-miR-3591-5p	CLIP-seq
MIRT2198118	hsa-miR-3662	CLIP-seq
MIRT2198119	hsa-miR-3663-3p	CLIP-seq
MIRT882335	hsa-miR-3666	CLIP-seq
MIRT2198120	hsa-miR-3678-5p	CLIP-seq
MIRT882338	hsa-miR-3691-3p	CLIP-seq
MIRT882349	hsa-miR-3919	CLIP-seq
MIRT882352	hsa-miR-3942-3p	CLIP-seq
MIRT1961427	hsa-miR-412	CLIP-seq
MIRT882354	hsa-miR-424	CLIP-seq
MIRT882359	hsa-miR-4295	CLIP-seq
MIRT2198121	hsa-miR-4480	CLIP-seq
MIRT2198122	hsa-miR-4485	CLIP-seq
MIRT2198123	hsa-miR-4503	CLIP-seq
MIRT882375	hsa-miR-454	CLIP-seq
MIRT882376	hsa-miR-455-3p	CLIP-seq
MIRT882380	hsa-miR-4660	CLIP-seq
MIRT2198124	hsa-miR-4676-5p	CLIP-seq
MIRT2198125	hsa-miR-4677-5p	CLIP-seq
MIRT2198126	hsa-miR-4687-5p	CLIP-seq
MIRT2198127	hsa-miR-4699-3p	CLIP-seq
MIRT2198128	hsa-miR-4711-5p	CLIP-seq
MIRT2198129	hsa-miR-4726-3p	CLIP-seq
MIRT2198130	hsa-miR-4732-5p	CLIP-seq
MIRT1961433	hsa-miR-4755-3p	CLIP-seq
MIRT882396	hsa-miR-4756-3p	CLIP-seq
MIRT2198131	hsa-miR-4786-3p	CLIP-seq
MIRT2198132	hsa-miR-494	CLIP-seq
MIRT882404	hsa-miR-497	CLIP-seq
MIRT882407	hsa-miR-513a-5p	CLIP-seq
MIRT882408	hsa-miR-519a	CLIP-seq
MIRT882409	hsa-miR-519b-3p	CLIP-seq
MIRT882410	hsa-miR-519c-3p	CLIP-seq
MIRT882411	hsa-miR-548a-5p	CLIP-seq
MIRT882412	hsa-miR-548ab	CLIP-seq
MIRT882413	hsa-miR-548ak	CLIP-seq
MIRT2198133	hsa-miR-548al	CLIP-seq
MIRT882415	hsa-miR-548b-5p	CLIP-seq
MIRT882416	hsa-miR-548c-5p	CLIP-seq
MIRT882417	hsa-miR-548d-5p	CLIP-seq
MIRT882418	hsa-miR-548h	CLIP-seq
MIRT882419	hsa-miR-548i	CLIP-seq
MIRT882420	hsa-miR-548j	CLIP-seq
MIRT882421	hsa-miR-548n	CLIP-seq
MIRT2198134	hsa-miR-548p	CLIP-seq
MIRT882422	hsa-miR-548w	CLIP-seq
MIRT882423	hsa-miR-548y	CLIP-seq
MIRT882425	hsa-miR-550b	CLIP-seq
MIRT882426	hsa-miR-559	CLIP-seq
MIRT2198135	hsa-miR-575	CLIP-seq
MIRT882429	hsa-miR-590-3p	CLIP-seq
MIRT882430	hsa-miR-590-5p	CLIP-seq
MIRT882431	hsa-miR-595	CLIP-seq
MIRT882435	hsa-miR-646	CLIP-seq
MIRT2198136	hsa-miR-671-5p	CLIP-seq
MIRT1961442	hsa-miR-764	CLIP-seq
MIRT2198137	hsa-miR-892a	CLIP-seq
MIRT1961444	hsa-miR-922	CLIP-seq
MIRT2198138	hsa-miR-936	CLIP-seq
MIRT882285	hsa-miR-146a	CLIP-seq
MIRT882286	hsa-miR-146b-5p	CLIP-seq
MIRT882299	hsa-miR-19a	CLIP-seq
MIRT882300	hsa-miR-19b	CLIP-seq
MIRT882349	hsa-miR-3919	CLIP-seq
MIRT2385889	hsa-miR-3925-5p	CLIP-seq
MIRT2385890	hsa-miR-4316	CLIP-seq
MIRT882396	hsa-miR-4756-3p	CLIP-seq
MIRT2385891	hsa-miR-514	CLIP-seq
MIRT2385892	hsa-miR-514b-3p	CLIP-seq
MIRT2385893	hsa-miR-642b	CLIP-seq
MIRT882271	hsa-miR-124	CLIP-seq
MIRT882299	hsa-miR-19a	CLIP-seq
MIRT882300	hsa-miR-19b	CLIP-seq
MIRT882303	hsa-miR-2113	CLIP-seq
MIRT882405	hsa-miR-506	CLIP-seq
MIRT882414	hsa-miR-548an	CLIP-seq
MIRT1961420	hsa-miR-3609	CLIP-seq
MIRT1961436	hsa-miR-520g	CLIP-seq
MIRT1961437	hsa-miR-520h	CLIP-seq
MIRT1961439	hsa-miR-548ah	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004142	Function	Diacylglycerol cholinephosphotransferase activity	NAS	9115637
GO:0004605	Function	Phosphatidate cytidylyltransferase activity	IDA	8863531, 9407135, 25375833
GO:0004605	Function	Phosphatidate cytidylyltransferase activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 33961781, 35271311
GO:0005783	Component	Endoplasmic reticulum	IDA	25375833, 26946540, 31548309
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005783	Component	Endoplasmic reticulum	ISS
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	ISS
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006657	Process	CDP-choline pathway	IEA
GO:0006661	Process	Phosphatidylinositol biosynthetic process	IDA	9407135
GO:0007165	Process	Signal transduction	NAS	9115637
GO:0007602	Process	Phototransduction	NAS	9806839
GO:0008654	Process	Phospholipid biosynthetic process	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016024	Process	CDP-diacylglycerol biosynthetic process	IDA	8863531
GO:0016024	Process	CDP-diacylglycerol biosynthetic process	IDA	9407135, 25375833
GO:0016024	Process	CDP-diacylglycerol biosynthetic process	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016772	Function	Transferase activity, transferring phosphorus-containing groups	IEA
GO:0016779	Function	Nucleotidyltransferase activity	IEA
GO:0045600	Process	Positive regulation of fat cell differentiation	IEA
GO:0045600	Process	Positive regulation of fat cell differentiation	ISS
GO:0140042	Process	Lipid droplet formation	IEA
GO:0140042	Process	Lipid droplet formation	IMP	26946540, 31548309

Other IDs

• MIM: 603548
• HGNC: 1800
• e!Ensembl: ENSG00000163624

Protein

• UniProt ID: Q92903
• Protein name: Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-DAG synthase 1) (CDP-DG synthase 1) (CDP-diacylglycerol synthase 1) (CDS 1) (CDP-diglyceride pyrophosphorylase 1) (CDP-diglyceride synthase 1) (CTP:phosphatidate cytidylyltransferase 1)
• Protein function: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol (PubMed:25375833, PubMed:9407135). Exhibits almost no ac
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01148	CTP_transf_1	87 → 417		Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver. {ECO:0000269|PubMed:9407135}.
• Sequence:

  MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPE
  IPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQV
  KCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLI
  RYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMI
  WFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSK
  YQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALS
  TFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRG
  PNPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPTLKV

• Sequence length: 461

Pathways

KEGG:

Glycerophospholipid metabolism
Metabolic pathways
Phosphatidylinositol signaling system

Reactome:

Synthesis of PI

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
CDS1-related disorder	Uncertain significance; Likely benign; Benign	rs139701286, rs2530037314, rs34695122, rs568659831, rs376285323, rs199711328, rs748866234, rs148659910, rs118099717, rs372703799, rs761209404	RCV003963723 RCV003397378 RCV003974259 RCV003931468 RCV003961354 RCV003936949 RCV003937034 RCV003951506 RCV003932277 RCV003954612 RCV003947260
Cervical cancer	Likely benign	rs528617646	RCV005903506
Familial cancer of breast	Likely benign	rs528617646	RCV005903505
Gastric cancer	Benign	rs376285323	RCV005933326
Lung cancer	Likely benign	rs528617646	RCV005903507
Lymphoma	Benign	rs376285323	RCV005933327
Uterine corpus endometrial carcinoma	Benign; Likely benign	rs376285323, rs528617646	RCV005933328 RCV005903508

Associations from Text Mining
Disease Name	Relationship Type	References
Ataxia Telangiectasia	Associate	9889122
Carcinoma Non Small Cell Lung	Associate	20980099
Colorectal Neoplasms	Associate	33378017
Neoplasm Metastasis	Associate	33378017