CORO2B (coronin 2B)

Gene

• Entrez ID: 10391
• Gene name: Coronin 2B
• Gene symbol: CORO2B
• Synonyms (NCBI Gene): CLIPINC
• Chromosome: 15
• Chromosome location: 15q23

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004703	hsa-miR-185-5p	Flow, Immunoblot, Microarray, qRT-PCR	19688090
MIRT017553	hsa-miR-335-5p	Microarray	18185580
MIRT024407	hsa-miR-215-5p	Microarray	19074876
MIRT026427	hsa-miR-192-5p	Microarray	19074876
MIRT904706	hsa-miR-106a	CLIP-seq
MIRT904707	hsa-miR-106b	CLIP-seq
MIRT904708	hsa-miR-1288	CLIP-seq
MIRT904709	hsa-miR-17	CLIP-seq
MIRT904710	hsa-miR-1915	CLIP-seq
MIRT904711	hsa-miR-20a	CLIP-seq
MIRT904712	hsa-miR-20b	CLIP-seq
MIRT904713	hsa-miR-2355-5p	CLIP-seq
MIRT904714	hsa-miR-298	CLIP-seq
MIRT904715	hsa-miR-3158-5p	CLIP-seq
MIRT904716	hsa-miR-3169	CLIP-seq
MIRT904717	hsa-miR-3609	CLIP-seq
MIRT904718	hsa-miR-3918	CLIP-seq
MIRT904719	hsa-miR-4297	CLIP-seq
MIRT904720	hsa-miR-4418	CLIP-seq
MIRT904721	hsa-miR-4685-5p	CLIP-seq
MIRT904722	hsa-miR-4796-3p	CLIP-seq
MIRT904723	hsa-miR-509-3-5p	CLIP-seq
MIRT904724	hsa-miR-509-5p	CLIP-seq
MIRT904725	hsa-miR-519d	CLIP-seq
MIRT904726	hsa-miR-548ah	CLIP-seq
MIRT904727	hsa-miR-93	CLIP-seq
MIRT904706	hsa-miR-106a	CLIP-seq
MIRT904707	hsa-miR-106b	CLIP-seq
MIRT904728	hsa-miR-1229	CLIP-seq
MIRT904708	hsa-miR-1288	CLIP-seq
MIRT904709	hsa-miR-17	CLIP-seq
MIRT904711	hsa-miR-20a	CLIP-seq
MIRT904712	hsa-miR-20b	CLIP-seq
MIRT904729	hsa-miR-2392	CLIP-seq
MIRT904714	hsa-miR-298	CLIP-seq
MIRT904715	hsa-miR-3158-5p	CLIP-seq
MIRT904730	hsa-miR-3161	CLIP-seq
MIRT904716	hsa-miR-3169	CLIP-seq
MIRT904731	hsa-miR-3180-5p	CLIP-seq
MIRT904732	hsa-miR-3192	CLIP-seq
MIRT904733	hsa-miR-3605-5p	CLIP-seq
MIRT904717	hsa-miR-3609	CLIP-seq
MIRT904734	hsa-miR-3689a-3p	CLIP-seq
MIRT904735	hsa-miR-3689c	CLIP-seq
MIRT904736	hsa-miR-3689d	CLIP-seq
MIRT904737	hsa-miR-382	CLIP-seq
MIRT904720	hsa-miR-4418	CLIP-seq
MIRT904738	hsa-miR-4534	CLIP-seq
MIRT904739	hsa-miR-4695-3p	CLIP-seq
MIRT904740	hsa-miR-4728-5p	CLIP-seq
MIRT904722	hsa-miR-4796-3p	CLIP-seq
MIRT904741	hsa-miR-4802-5p	CLIP-seq
MIRT904723	hsa-miR-509-3-5p	CLIP-seq
MIRT904724	hsa-miR-509-5p	CLIP-seq
MIRT904725	hsa-miR-519d	CLIP-seq
MIRT904742	hsa-miR-520a-5p	CLIP-seq
MIRT904743	hsa-miR-525-5p	CLIP-seq
MIRT904744	hsa-miR-526b	CLIP-seq
MIRT904726	hsa-miR-548ah	CLIP-seq
MIRT904745	hsa-miR-570	CLIP-seq
MIRT904746	hsa-miR-592	CLIP-seq
MIRT904747	hsa-miR-597	CLIP-seq
MIRT904727	hsa-miR-93	CLIP-seq
MIRT1921454	hsa-miR-3929	CLIP-seq
MIRT1921455	hsa-miR-4419b	CLIP-seq
MIRT1921456	hsa-miR-4478	CLIP-seq
MIRT1921457	hsa-miR-4766-5p	CLIP-seq
MIRT904722	hsa-miR-4796-3p	CLIP-seq
MIRT1968302	hsa-miR-3176	CLIP-seq
MIRT1968303	hsa-miR-3189-3p	CLIP-seq
MIRT904734	hsa-miR-3689a-3p	CLIP-seq
MIRT904735	hsa-miR-3689c	CLIP-seq
MIRT1968304	hsa-miR-3922-3p	CLIP-seq
MIRT904706	hsa-miR-106a	CLIP-seq
MIRT904707	hsa-miR-106b	CLIP-seq
MIRT1968305	hsa-miR-1183	CLIP-seq
MIRT904708	hsa-miR-1288	CLIP-seq
MIRT904709	hsa-miR-17	CLIP-seq
MIRT904711	hsa-miR-20a	CLIP-seq
MIRT904712	hsa-miR-20b	CLIP-seq
MIRT904714	hsa-miR-298	CLIP-seq
MIRT1968306	hsa-miR-302a	CLIP-seq
MIRT1968307	hsa-miR-302b	CLIP-seq
MIRT1968308	hsa-miR-302c	CLIP-seq
MIRT1968309	hsa-miR-302d	CLIP-seq
MIRT1968310	hsa-miR-302e	CLIP-seq
MIRT1968311	hsa-miR-3150b-3p	CLIP-seq
MIRT904715	hsa-miR-3158-5p	CLIP-seq
MIRT904716	hsa-miR-3169	CLIP-seq
MIRT904717	hsa-miR-3609	CLIP-seq
MIRT1968312	hsa-miR-372	CLIP-seq
MIRT1968313	hsa-miR-373	CLIP-seq
MIRT904720	hsa-miR-4418	CLIP-seq
MIRT1968314	hsa-miR-4689	CLIP-seq
MIRT1968315	hsa-miR-4695-5p	CLIP-seq
MIRT1968316	hsa-miR-4710	CLIP-seq
MIRT1968317	hsa-miR-4784	CLIP-seq
MIRT904722	hsa-miR-4796-3p	CLIP-seq
MIRT904723	hsa-miR-509-3-5p	CLIP-seq
MIRT904724	hsa-miR-509-5p	CLIP-seq
MIRT904725	hsa-miR-519d	CLIP-seq
MIRT1968318	hsa-miR-520a-3p	CLIP-seq
MIRT1968319	hsa-miR-520b	CLIP-seq
MIRT1968320	hsa-miR-520c-3p	CLIP-seq
MIRT1968321	hsa-miR-520d-3p	CLIP-seq
MIRT1968322	hsa-miR-520e	CLIP-seq
MIRT904726	hsa-miR-548ah	CLIP-seq
MIRT904727	hsa-miR-93	CLIP-seq
MIRT904706	hsa-miR-106a	CLIP-seq
MIRT904707	hsa-miR-106b	CLIP-seq
MIRT904708	hsa-miR-1288	CLIP-seq
MIRT904709	hsa-miR-17	CLIP-seq
MIRT904711	hsa-miR-20a	CLIP-seq
MIRT904712	hsa-miR-20b	CLIP-seq
MIRT904714	hsa-miR-298	CLIP-seq
MIRT2204133	hsa-miR-299-3p	CLIP-seq
MIRT1968306	hsa-miR-302a	CLIP-seq
MIRT1968307	hsa-miR-302b	CLIP-seq
MIRT1968308	hsa-miR-302c	CLIP-seq
MIRT1968309	hsa-miR-302d	CLIP-seq
MIRT1968310	hsa-miR-302e	CLIP-seq
MIRT904715	hsa-miR-3158-5p	CLIP-seq
MIRT904716	hsa-miR-3169	CLIP-seq
MIRT2204134	hsa-miR-34b	CLIP-seq
MIRT904717	hsa-miR-3609	CLIP-seq
MIRT904734	hsa-miR-3689a-3p	CLIP-seq
MIRT904735	hsa-miR-3689c	CLIP-seq
MIRT1968312	hsa-miR-372	CLIP-seq
MIRT1968313	hsa-miR-373	CLIP-seq
MIRT904720	hsa-miR-4418	CLIP-seq
MIRT2204135	hsa-miR-4648	CLIP-seq
MIRT2204136	hsa-miR-4654	CLIP-seq
MIRT904740	hsa-miR-4728-5p	CLIP-seq
MIRT2204137	hsa-miR-4769-5p	CLIP-seq
MIRT904722	hsa-miR-4796-3p	CLIP-seq
MIRT904723	hsa-miR-509-3-5p	CLIP-seq
MIRT904724	hsa-miR-509-5p	CLIP-seq
MIRT904725	hsa-miR-519d	CLIP-seq
MIRT1968318	hsa-miR-520a-3p	CLIP-seq
MIRT1968319	hsa-miR-520b	CLIP-seq
MIRT1968320	hsa-miR-520c-3p	CLIP-seq
MIRT1968321	hsa-miR-520d-3p	CLIP-seq
MIRT1968322	hsa-miR-520e	CLIP-seq
MIRT904726	hsa-miR-548ah	CLIP-seq
MIRT904727	hsa-miR-93	CLIP-seq
MIRT1968305	hsa-miR-1183	CLIP-seq
MIRT904729	hsa-miR-2392	CLIP-seq
MIRT2386379	hsa-miR-3064-5p	CLIP-seq
MIRT2386380	hsa-miR-3117-5p	CLIP-seq
MIRT2386381	hsa-miR-3137	CLIP-seq
MIRT1968311	hsa-miR-3150b-3p	CLIP-seq
MIRT2386382	hsa-miR-3151	CLIP-seq
MIRT904732	hsa-miR-3192	CLIP-seq
MIRT904733	hsa-miR-3605-5p	CLIP-seq
MIRT2386383	hsa-miR-3652	CLIP-seq
MIRT904734	hsa-miR-3689a-3p	CLIP-seq
MIRT904735	hsa-miR-3689c	CLIP-seq
MIRT904736	hsa-miR-3689d	CLIP-seq
MIRT2386384	hsa-miR-4430	CLIP-seq
MIRT2386385	hsa-miR-4447	CLIP-seq
MIRT2386386	hsa-miR-4472	CLIP-seq
MIRT2386387	hsa-miR-4505	CLIP-seq
MIRT904738	hsa-miR-4534	CLIP-seq
MIRT1968314	hsa-miR-4689	CLIP-seq
MIRT1968315	hsa-miR-4695-5p	CLIP-seq
MIRT1968316	hsa-miR-4710	CLIP-seq
MIRT904740	hsa-miR-4728-5p	CLIP-seq
MIRT1968317	hsa-miR-4784	CLIP-seq
MIRT904741	hsa-miR-4802-5p	CLIP-seq
MIRT2386388	hsa-miR-491-5p	CLIP-seq
MIRT904734	hsa-miR-3689a-3p	CLIP-seq
MIRT904735	hsa-miR-3689c	CLIP-seq
MIRT2386389	hsa-miR-593	CLIP-seq
MIRT1968305	hsa-miR-1183	CLIP-seq
MIRT2507583	hsa-miR-1225-5p	CLIP-seq
MIRT2507584	hsa-miR-1250	CLIP-seq
MIRT2507585	hsa-miR-1263	CLIP-seq
MIRT2507586	hsa-miR-1273f	CLIP-seq
MIRT2507587	hsa-miR-129-3p	CLIP-seq
MIRT2507588	hsa-miR-143	CLIP-seq
MIRT904710	hsa-miR-1915	CLIP-seq
MIRT2507589	hsa-miR-2115	CLIP-seq
MIRT904713	hsa-miR-2355-5p	CLIP-seq
MIRT904729	hsa-miR-2392	CLIP-seq
MIRT2507590	hsa-miR-27a	CLIP-seq
MIRT2507591	hsa-miR-27b	CLIP-seq
MIRT2507592	hsa-miR-2964a-5p	CLIP-seq
MIRT2386379	hsa-miR-3064-5p	CLIP-seq
MIRT2386380	hsa-miR-3117-5p	CLIP-seq
MIRT2507593	hsa-miR-3127-3p	CLIP-seq
MIRT2507594	hsa-miR-3132	CLIP-seq
MIRT2386381	hsa-miR-3137	CLIP-seq
MIRT1968311	hsa-miR-3150b-3p	CLIP-seq
MIRT2386382	hsa-miR-3151	CLIP-seq
MIRT1968302	hsa-miR-3176	CLIP-seq
MIRT2507595	hsa-miR-3184	CLIP-seq
MIRT904732	hsa-miR-3192	CLIP-seq
MIRT2507596	hsa-miR-324-5p	CLIP-seq
MIRT2507597	hsa-miR-346	CLIP-seq
MIRT904733	hsa-miR-3605-5p	CLIP-seq
MIRT2507598	hsa-miR-3622a-3p	CLIP-seq
MIRT2507599	hsa-miR-3622b-3p	CLIP-seq
MIRT2386383	hsa-miR-3652	CLIP-seq
MIRT2507600	hsa-miR-3663-5p	CLIP-seq
MIRT904734	hsa-miR-3689a-3p	CLIP-seq
MIRT904735	hsa-miR-3689c	CLIP-seq
MIRT904736	hsa-miR-3689d	CLIP-seq
MIRT904718	hsa-miR-3918	CLIP-seq
MIRT1968304	hsa-miR-3922-3p	CLIP-seq
MIRT2507601	hsa-miR-3937	CLIP-seq
MIRT2507602	hsa-miR-3943	CLIP-seq
MIRT2507603	hsa-miR-423-5p	CLIP-seq
MIRT2507604	hsa-miR-4254	CLIP-seq
MIRT2507605	hsa-miR-4267	CLIP-seq
MIRT2507606	hsa-miR-4276	CLIP-seq
MIRT904719	hsa-miR-4297	CLIP-seq
MIRT2507607	hsa-miR-4313	CLIP-seq
MIRT2507608	hsa-miR-4318	CLIP-seq
MIRT2507609	hsa-miR-4321	CLIP-seq
MIRT2507610	hsa-miR-4329	CLIP-seq
MIRT2386384	hsa-miR-4430	CLIP-seq
MIRT2386385	hsa-miR-4447	CLIP-seq
MIRT2507611	hsa-miR-4459	CLIP-seq
MIRT2386386	hsa-miR-4472	CLIP-seq
MIRT2386387	hsa-miR-4505	CLIP-seq
MIRT2507612	hsa-miR-4527	CLIP-seq
MIRT904738	hsa-miR-4534	CLIP-seq
MIRT2507613	hsa-miR-4536	CLIP-seq
MIRT2507614	hsa-miR-4645-5p	CLIP-seq
MIRT2507615	hsa-miR-4663	CLIP-seq
MIRT2507616	hsa-miR-4668-5p	CLIP-seq
MIRT2507617	hsa-miR-4673	CLIP-seq
MIRT904721	hsa-miR-4685-5p	CLIP-seq
MIRT2507618	hsa-miR-4687-5p	CLIP-seq
MIRT1968314	hsa-miR-4689	CLIP-seq
MIRT1968315	hsa-miR-4695-5p	CLIP-seq
MIRT2507619	hsa-miR-4708-5p	CLIP-seq
MIRT1968316	hsa-miR-4710	CLIP-seq
MIRT2507620	hsa-miR-4724-3p	CLIP-seq
MIRT2507621	hsa-miR-4725-5p	CLIP-seq
MIRT2507622	hsa-miR-4728-3p	CLIP-seq
MIRT904740	hsa-miR-4728-5p	CLIP-seq
MIRT2507623	hsa-miR-4746-3p	CLIP-seq
MIRT2507624	hsa-miR-4757-5p	CLIP-seq
MIRT2507625	hsa-miR-4770	CLIP-seq
MIRT1968317	hsa-miR-4784	CLIP-seq
MIRT2507626	hsa-miR-4786-3p	CLIP-seq
MIRT904741	hsa-miR-4802-5p	CLIP-seq
MIRT2386388	hsa-miR-491-5p	CLIP-seq
MIRT2507627	hsa-miR-504	CLIP-seq
MIRT2507628	hsa-miR-512-3p	CLIP-seq
MIRT2507629	hsa-miR-513a-5p	CLIP-seq
MIRT2507630	hsa-miR-619	CLIP-seq
MIRT2507631	hsa-miR-665	CLIP-seq
MIRT2507632	hsa-miR-885-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003093	Process	Regulation of glomerular filtration	IEA
GO:0003779	Function	Actin binding	IEA
GO:0003779	Function	Actin binding	NAS	10224093
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005925	Component	Focal adhesion	IDA	29162887
GO:0005925	Component	Focal adhesion	IEA
GO:0010812	Process	Negative regulation of cell-substrate adhesion	IDA	29162887
GO:0015629	Component	Actin cytoskeleton	NAS	10224093
GO:0016020	Component	Membrane	NAS	10224093
GO:0017166	Function	Vinculin binding	IPI	29162887
GO:0030036	Process	Actin cytoskeleton organization	NAS	10224093
GO:0032956	Process	Regulation of actin cytoskeleton organization	IDA	29162887
GO:0048041	Process	Focal adhesion assembly	IEA
GO:0051015	Function	Actin filament binding	IBA
GO:0051497	Process	Negative regulation of stress fiber assembly	IEA
GO:0080135	Process	Regulation of cellular response to stress	IDA	29162887
GO:1904950	Process	Negative regulation of establishment of protein localization	IDA	29162887
GO:1904951	Process	Positive regulation of establishment of protein localization	IDA	29162887
GO:1990147	Function	Talin binding	IDA	29162887

Other IDs

• MIM: 605002
• HGNC: 2256
• e!Ensembl: ENSG00000103647

Protein

• UniProt ID: Q9UQ03
• Protein name: Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
• Protein function: May play a role in the reorganization of neuronal actin structure.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08953	DUF1899	10 → 75	Domain of unknown function (DUF1899)	Domain
  PF00400	WD40	78 → 116	WD domain, G-beta repeat	Repeat
  PF00400	WD40	170 → 208	WD domain, G-beta repeat	Repeat
  PF16300	WD40_4	350 → 392		Repeat

• Tissue specificity: TISSUE SPECIFICITY: Expressed predominantly in brain.
• Sequence:

  MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESA
  GGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEG
  GLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHT
  DVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTT
  GVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEI
  STEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRR
  SDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVV
  VNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNSPKNC
  

• Sequence length: 480