Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	10365
Gene name	KLF transcription factor 2
Gene symbol	KLF2
Synonyms (NCBI Gene)	LKLF
Chromosome	19
Chromosome location	19p13.11
Summary	This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in

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miRTarBase ID	miRNA	Experiments	Reference
MIRT006372	hsa-miR-92a-3p	Luciferase reporter assay	21768538
MIRT006372	hsa-miR-92a-3p	Luciferase reporter assay	21768538
MIRT006372	hsa-miR-92a-3p	Luciferase reporter assay	21768538
MIRT023028	hsa-miR-124-3p	Microarray	18668037
MIRT006372	hsa-miR-92a-3p	Other	21768538
MIRT719862	hsa-miR-1228-3p	HITS-CLIP	19536157
MIRT719861	hsa-miR-4301	HITS-CLIP	19536157
MIRT719860	hsa-miR-5193	HITS-CLIP	19536157
MIRT719859	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT719858	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT719857	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT719856	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT719855	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT719853	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT719854	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT719862	hsa-miR-1228-3p	HITS-CLIP	19536157
MIRT719861	hsa-miR-4301	HITS-CLIP	19536157
MIRT719860	hsa-miR-5193	HITS-CLIP	19536157
MIRT719859	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT719858	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT719857	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT719856	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT719855	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT719853	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT719854	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT650273	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT711854	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT650272	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT650271	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT650270	hsa-miR-942-5p	HITS-CLIP	19536157
MIRT650269	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT650267	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT650266	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT650265	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT687716	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT687715	hsa-miR-4668-3p	HITS-CLIP	23313552
MIRT687714	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT687713	hsa-miR-942-3p	HITS-CLIP	23313552
MIRT687712	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT687711	hsa-miR-3926	HITS-CLIP	23313552
MIRT687710	hsa-miR-548s	HITS-CLIP	23313552
MIRT673885	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT673886	hsa-miR-5007-5p	HITS-CLIP	23824327
MIRT673884	hsa-miR-3155a	HITS-CLIP	23824327
MIRT673883	hsa-miR-3155b	HITS-CLIP	23824327
MIRT673882	hsa-miR-484	HITS-CLIP	23824327
MIRT673880	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT673881	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT673879	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT673877	hsa-miR-4518	HITS-CLIP	23824327
MIRT673878	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT673876	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT673875	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT673874	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT673873	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT673871	hsa-miR-3672	HITS-CLIP	23824327
MIRT673872	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT673870	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT673869	hsa-miR-8055	HITS-CLIP	23824327
MIRT532248	hsa-miR-548aa	HITS-CLIP	23824327
MIRT532247	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT532246	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT532245	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT532244	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT532243	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT650277	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT650278	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT650276	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT532234	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT532233	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT665001	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT650275	hsa-miR-1305	HITS-CLIP	23824327
MIRT665000	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT532248	hsa-miR-548aa	HITS-CLIP	23824327
MIRT532247	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT532246	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT532245	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT532244	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT532243	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT650277	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT650278	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT650276	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT532234	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT532233	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT532229	hsa-miR-6802-3p	HITS-CLIP	23824327
MIRT650275	hsa-miR-1305	HITS-CLIP	23824327
MIRT650274	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT650273	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT650272	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT650271	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT650270	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT650269	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT650268	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT650267	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT650266	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT650265	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT532248	hsa-miR-548aa	PAR-CLIP	22012620
MIRT532247	hsa-miR-548ap-3p	PAR-CLIP	22012620
MIRT532246	hsa-miR-548t-3p	PAR-CLIP	22012620
MIRT532245	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT532244	hsa-miR-548at-3p	PAR-CLIP	22012620
MIRT532243	hsa-miR-548ay-3p	PAR-CLIP	22012620
MIRT532242	hsa-miR-1285-5p	PAR-CLIP	22012620
MIRT532241	hsa-miR-6715a-3p	PAR-CLIP	22012620
MIRT532240	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT532239	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT532238	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT532237	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT532236	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT532235	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT532234	hsa-miR-412-3p	PAR-CLIP	22012620
MIRT532233	hsa-miR-6754-3p	PAR-CLIP	22012620
MIRT532232	hsa-miR-4786-5p	PAR-CLIP	22012620
MIRT532231	hsa-miR-769-5p	PAR-CLIP	22012620
MIRT532230	hsa-miR-6715b-3p	PAR-CLIP	22012620
MIRT532229	hsa-miR-6802-3p	PAR-CLIP	22012620
MIRT474624	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT474623	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT474622	hsa-miR-940	PAR-CLIP	23446348
MIRT474621	hsa-miR-4459	PAR-CLIP	23446348
MIRT474620	hsa-miR-665	PAR-CLIP	23446348
MIRT474619	hsa-miR-6840-3p	PAR-CLIP	23446348
MIRT474617	hsa-miR-1827	PAR-CLIP	23446348
MIRT474615	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT474616	hsa-miR-6894-5p	PAR-CLIP	23446348
MIRT474624	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT474623	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT474622	hsa-miR-940	PAR-CLIP	23592263
MIRT474621	hsa-miR-4459	PAR-CLIP	23592263
MIRT474620	hsa-miR-665	PAR-CLIP	23592263
MIRT474619	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT474618	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT474617	hsa-miR-1827	PAR-CLIP	23592263
MIRT474615	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT474616	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT474614	hsa-miR-1273e	PAR-CLIP	23592263
MIRT006372	hsa-miR-92a-3p	ImmunohistochemistryqRT-PCRWestern blot	27411964
MIRT006372	hsa-miR-92a-3p	ImmunohistochemistryqRT-PCRWestern blot	27411964
MIRT474614	hsa-miR-1273e	PAR-CLIP	27292025
MIRT474614	hsa-miR-1273e	PAR-CLIP	27292025
MIRT474617	hsa-miR-1827	PAR-CLIP	27292025
MIRT474621	hsa-miR-4459	PAR-CLIP	27292025
MIRT474620	hsa-miR-665	PAR-CLIP	27292025
MIRT474619	hsa-miR-6840-3p	PAR-CLIP	27292025
MIRT474619	hsa-miR-6840-3p	PAR-CLIP	27292025
MIRT733413	hsa-miR-15b-3p	qRT-PCRWestern blotting	34224334
MIRT736061	hsa-miR-32-5p	Luciferase reporter assayWestern blotting	31497207
MIRT719862	hsa-miR-1228-3p	HITS-CLIP	19536157
MIRT719861	hsa-miR-4301	HITS-CLIP	19536157
MIRT719860	hsa-miR-5193	HITS-CLIP	19536157
MIRT719859	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT719858	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT719857	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT719856	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT719855	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT719853	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT719854	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT719862	hsa-miR-1228-3p	HITS-CLIP	19536157
MIRT719861	hsa-miR-4301	HITS-CLIP	19536157
MIRT719860	hsa-miR-5193	HITS-CLIP	19536157
MIRT719859	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT719858	hsa-miR-532-3p	HITS-CLIP	19536157
MIRT719857	hsa-miR-377-3p	HITS-CLIP	19536157
MIRT719856	hsa-miR-3156-3p	HITS-CLIP	19536157
MIRT719855	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT719853	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT719854	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT650273	hsa-miR-7110-3p	HITS-CLIP	19536157
MIRT711854	hsa-miR-6817-3p	HITS-CLIP	19536157
MIRT650272	hsa-miR-6515-3p	HITS-CLIP	19536157
MIRT650271	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT650270	hsa-miR-942-5p	HITS-CLIP	19536157
MIRT650269	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT650267	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT650266	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT650265	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT687716	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT687715	hsa-miR-4668-3p	HITS-CLIP	23313552
MIRT687714	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT687713	hsa-miR-942-3p	HITS-CLIP	23313552
MIRT687712	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT687711	hsa-miR-3926	HITS-CLIP	23313552
MIRT687710	hsa-miR-548s	HITS-CLIP	23313552
MIRT673885	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT673886	hsa-miR-5007-5p	HITS-CLIP	23824327
MIRT673884	hsa-miR-3155a	HITS-CLIP	23824327
MIRT673883	hsa-miR-3155b	HITS-CLIP	23824327
MIRT673882	hsa-miR-484	HITS-CLIP	23824327
MIRT673880	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT673881	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT673879	hsa-miR-1266-5p	HITS-CLIP	23824327
MIRT673877	hsa-miR-4518	HITS-CLIP	23824327
MIRT673878	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT673876	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT673875	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT673874	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT673873	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT673871	hsa-miR-3672	HITS-CLIP	23824327
MIRT673872	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT673870	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT673869	hsa-miR-8055	HITS-CLIP	23824327
MIRT532248	hsa-miR-548aa	HITS-CLIP	23824327
MIRT532247	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT532246	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT532245	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT532244	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT532243	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT650277	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT650278	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT650276	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT532234	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT532233	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT665001	hsa-miR-5591-3p	HITS-CLIP	23824327
MIRT650275	hsa-miR-1305	HITS-CLIP	23824327
MIRT665000	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT532248	hsa-miR-548aa	HITS-CLIP	23824327
MIRT532247	hsa-miR-548ap-3p	HITS-CLIP	23824327
MIRT532246	hsa-miR-548t-3p	HITS-CLIP	23824327
MIRT532245	hsa-miR-548as-3p	HITS-CLIP	23824327
MIRT532244	hsa-miR-548at-3p	HITS-CLIP	23824327
MIRT532243	hsa-miR-548ay-3p	HITS-CLIP	23824327
MIRT650277	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT650278	hsa-miR-3620-3p	HITS-CLIP	23824327
MIRT650276	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT532234	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT532233	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT532229	hsa-miR-6802-3p	HITS-CLIP	23824327
MIRT650275	hsa-miR-1305	HITS-CLIP	23824327
MIRT650274	hsa-miR-6840-5p	HITS-CLIP	23824327
MIRT650273	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT650272	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT650271	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT650270	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT650269	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT650268	hsa-miR-3679-3p	HITS-CLIP	23824327
MIRT650267	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT650266	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT650265	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT532248	hsa-miR-548aa	PAR-CLIP	22012620
MIRT532247	hsa-miR-548ap-3p	PAR-CLIP	22012620
MIRT532246	hsa-miR-548t-3p	PAR-CLIP	22012620
MIRT532245	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT532244	hsa-miR-548at-3p	PAR-CLIP	22012620
MIRT532243	hsa-miR-548ay-3p	PAR-CLIP	22012620
MIRT532242	hsa-miR-1285-5p	PAR-CLIP	22012620
MIRT532241	hsa-miR-6715a-3p	PAR-CLIP	22012620
MIRT532240	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT532239	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT532238	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT532237	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT532236	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT532235	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT532234	hsa-miR-412-3p	PAR-CLIP	22012620
MIRT532233	hsa-miR-6754-3p	PAR-CLIP	22012620
MIRT532232	hsa-miR-4786-5p	PAR-CLIP	22012620
MIRT532231	hsa-miR-769-5p	PAR-CLIP	22012620
MIRT532230	hsa-miR-6715b-3p	PAR-CLIP	22012620
MIRT532229	hsa-miR-6802-3p	PAR-CLIP	22012620
MIRT474624	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT474623	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT474622	hsa-miR-940	PAR-CLIP	23446348
MIRT474621	hsa-miR-4459	PAR-CLIP	23446348
MIRT474620	hsa-miR-665	PAR-CLIP	23446348
MIRT474619	hsa-miR-6840-3p	PAR-CLIP	23446348
MIRT474617	hsa-miR-1827	PAR-CLIP	23446348
MIRT474615	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT474616	hsa-miR-6894-5p	PAR-CLIP	23446348
MIRT474624	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT474623	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT474622	hsa-miR-940	PAR-CLIP	23592263
MIRT474621	hsa-miR-4459	PAR-CLIP	23592263
MIRT474620	hsa-miR-665	PAR-CLIP	23592263
MIRT474619	hsa-miR-6840-3p	PAR-CLIP	23592263
MIRT474618	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT474617	hsa-miR-1827	PAR-CLIP	23592263
MIRT474615	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT474616	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT474614	hsa-miR-1273e	PAR-CLIP	23592263
MIRT1096328	hsa-miR-101	CLIP-seq
MIRT1096329	hsa-miR-1253	CLIP-seq
MIRT1096330	hsa-miR-1324	CLIP-seq
MIRT1096331	hsa-miR-185	CLIP-seq
MIRT1096332	hsa-miR-300	CLIP-seq
MIRT1096333	hsa-miR-3122	CLIP-seq
MIRT1096334	hsa-miR-3163	CLIP-seq
MIRT1096335	hsa-miR-3166	CLIP-seq
MIRT1096336	hsa-miR-338-5p	CLIP-seq
MIRT1096337	hsa-miR-340	CLIP-seq
MIRT1096338	hsa-miR-3689a-3p	CLIP-seq
MIRT1096339	hsa-miR-3689c	CLIP-seq
MIRT1096340	hsa-miR-381	CLIP-seq
MIRT1096341	hsa-miR-3913-5p	CLIP-seq
MIRT1096342	hsa-miR-4280	CLIP-seq
MIRT1096343	hsa-miR-4306	CLIP-seq
MIRT1096344	hsa-miR-4644	CLIP-seq
MIRT1096345	hsa-miR-4645-3p	CLIP-seq
MIRT1096346	hsa-miR-4666-3p	CLIP-seq
MIRT1096347	hsa-miR-4704-3p	CLIP-seq
MIRT1096348	hsa-miR-4728-5p	CLIP-seq
MIRT1096349	hsa-miR-4783-3p	CLIP-seq
MIRT1096350	hsa-miR-656	CLIP-seq
MIRT1096332	hsa-miR-300	CLIP-seq
MIRT1096334	hsa-miR-3163	CLIP-seq
MIRT1096336	hsa-miR-338-5p	CLIP-seq
MIRT1096337	hsa-miR-340	CLIP-seq
MIRT1096340	hsa-miR-381	CLIP-seq
MIRT1096346	hsa-miR-4666-3p	CLIP-seq
MIRT1096350	hsa-miR-656	CLIP-seq
MIRT1096328	hsa-miR-101	CLIP-seq
MIRT2257046	hsa-miR-1229	CLIP-seq
MIRT1096329	hsa-miR-1253	CLIP-seq
MIRT2257047	hsa-miR-128	CLIP-seq
MIRT2257048	hsa-miR-1293	CLIP-seq
MIRT1096330	hsa-miR-1324	CLIP-seq
MIRT2257049	hsa-miR-137	CLIP-seq
MIRT2257050	hsa-miR-1538	CLIP-seq
MIRT2257051	hsa-miR-2117	CLIP-seq
MIRT2257052	hsa-miR-223	CLIP-seq
MIRT2257053	hsa-miR-25	CLIP-seq
MIRT2257054	hsa-miR-27a	CLIP-seq
MIRT2257055	hsa-miR-27b	CLIP-seq
MIRT1096332	hsa-miR-300	CLIP-seq
MIRT1096333	hsa-miR-3122	CLIP-seq
MIRT2257056	hsa-miR-3137	CLIP-seq
MIRT1096335	hsa-miR-3166	CLIP-seq
MIRT2257057	hsa-miR-32	CLIP-seq
MIRT2257058	hsa-miR-323b-3p	CLIP-seq
MIRT2257059	hsa-miR-326	CLIP-seq
MIRT2257060	hsa-miR-330-5p	CLIP-seq
MIRT1096336	hsa-miR-338-5p	CLIP-seq
MIRT2257061	hsa-miR-342-3p	CLIP-seq
MIRT2257062	hsa-miR-342-5p	CLIP-seq
MIRT2257063	hsa-miR-363	CLIP-seq
MIRT2257064	hsa-miR-367	CLIP-seq
MIRT1096338	hsa-miR-3689a-3p	CLIP-seq
MIRT1096339	hsa-miR-3689c	CLIP-seq
MIRT1096340	hsa-miR-381	CLIP-seq
MIRT2257065	hsa-miR-3910	CLIP-seq
MIRT1096341	hsa-miR-3913-5p	CLIP-seq
MIRT2257066	hsa-miR-4419a	CLIP-seq
MIRT2257067	hsa-miR-4457	CLIP-seq
MIRT2257068	hsa-miR-4483	CLIP-seq
MIRT2257069	hsa-miR-4492	CLIP-seq
MIRT2257070	hsa-miR-4498	CLIP-seq
MIRT2257071	hsa-miR-4505	CLIP-seq
MIRT2257072	hsa-miR-4510	CLIP-seq
MIRT1096345	hsa-miR-4645-3p	CLIP-seq
MIRT2257073	hsa-miR-4651	CLIP-seq
MIRT2257074	hsa-miR-4664-5p	CLIP-seq
MIRT1096346	hsa-miR-4666-3p	CLIP-seq
MIRT2257075	hsa-miR-4697-3p	CLIP-seq
MIRT1096347	hsa-miR-4704-3p	CLIP-seq
MIRT1096348	hsa-miR-4728-5p	CLIP-seq
MIRT2257076	hsa-miR-4731-5p	CLIP-seq
MIRT2257077	hsa-miR-4745-3p	CLIP-seq
MIRT2257078	hsa-miR-4753-5p	CLIP-seq
MIRT2257079	hsa-miR-483-5p	CLIP-seq
MIRT2257080	hsa-miR-513b	CLIP-seq
MIRT2257081	hsa-miR-608	CLIP-seq
MIRT1096350	hsa-miR-656	CLIP-seq
MIRT2257082	hsa-miR-671-3p	CLIP-seq
MIRT2257083	hsa-miR-762	CLIP-seq
MIRT2257084	hsa-miR-92a	CLIP-seq
MIRT2257085	hsa-miR-92b	CLIP-seq
MIRT2257086	hsa-miR-938	CLIP-seq
MIRT2257087	hsa-miR-944	CLIP-seq
MIRT2257046	hsa-miR-1229	CLIP-seq
MIRT2257061	hsa-miR-342-3p	CLIP-seq
MIRT2257067	hsa-miR-4457	CLIP-seq
MIRT1096347	hsa-miR-4704-3p	CLIP-seq
MIRT2257080	hsa-miR-513b	CLIP-seq
MIRT2389923	hsa-miR-548ac	CLIP-seq
MIRT2389924	hsa-miR-548d-3p	CLIP-seq
MIRT2389925	hsa-miR-548z	CLIP-seq
MIRT1096346	hsa-miR-4666-3p	CLIP-seq
MIRT1096346	hsa-miR-4666-3p	CLIP-seq

Show/Hide all (4)

Transcription factor	Regulation	Reference
FOXO1	Unknown	23002242
HNRNPD	Unknown	15835916
NANOG	Activation	22378194
TP53	Repression	23202365

Show/Hide all (45)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	26299712
GO:0000785	Component	Chromatin	IEA
GO:0000785	Component	Chromatin	IMP	22327366
GO:0000785	Component	Chromatin	ISA
GO:0000902	Process	Cell morphogenesis	IEA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IMP	22327366
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001701	Process	In utero embryonic development	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003677	Function	DNA binding	IMP	22327366
GO:0003700	Function	DNA-binding transcription factor activity	IDA	21063504
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	16617118, 21382345
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0032715	Process	Negative regulation of interleukin-6 production	IEA
GO:0034101	Process	Erythrocyte homeostasis	IEA
GO:0034616	Process	Response to laminar fluid shear stress	IEA
GO:0035264	Process	Multicellular organism growth	IEA
GO:0040029	Process	Epigenetic regulation of gene expression	IEA
GO:0042311	Process	Vasodilation	IMP	21768538
GO:0043249	Process	Erythrocyte maturation	IEA
GO:0045429	Process	Positive regulation of nitric oxide biosynthetic process	IDA	21768538
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	21063504
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IGI	20551324
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	22327366, 23043106
GO:0046872	Function	Metal ion binding	IEA
GO:0048386	Process	Positive regulation of retinoic acid receptor signaling pathway	IDA	26416422
GO:0051247	Process	Positive regulation of protein metabolic process	IGI	20551324
GO:0060509	Process	Type I pneumocyte differentiation	IEA
GO:0070301	Process	Cellular response to hydrogen peroxide	IEA
GO:0071347	Process	Cellular response to interleukin-1	IEA
GO:0071356	Process	Cellular response to tumor necrosis factor	IEA
GO:0071498	Process	Cellular response to fluid shear stress	IMP	22327366
GO:0071499	Process	Cellular response to laminar fluid shear stress	IMP	23043106
GO:0097533	Process	Cellular stress response to acid chemical	IMP	26299712
GO:1903671	Process	Negative regulation of sprouting angiogenesis	IMP	26299712
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990859	Process	Cellular response to endothelin	IEA

MIM	HGNC	e!Ensembl
602016	6347	ENSG00000127528

Q9Y5W3

Protein name

Krueppel-like factor 2 (Lung krueppel-like factor)

Protein function

Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription (PubMed:21063504). Might be involved in transcriptional regulation by modulating the binding of the

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00096	zf-C2H2	272 → 296	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	302 → 326	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	332 → 354	Zinc finger, C2H2 type	Domain

Sequence

MALSEPILPSFSTFASPCRERGLQERWPRAEPESGGTDDDLNSVLDFILSMGLDGLGAEA
APEPPPPPPPPAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPLGPALHGRFLLAPPGRL
VKAEPPEADGGGGYGCAPGLTRGPRGLKREGAPGPAASCMRGPGGRPPPPPDTPPLSPDG
PARLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAPPAFGLFDDAAAAAAALGLAPPAAR
GLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEK
PYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM

Sequence length

355

Interactions

View interactions

	KEGG
	FoxO signaling pathway Apelin signaling pathway Fluid shear stress and atherosclerosis

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs7248864	RCV005917205
Inherited Immunodeficiency Diseases	Likely pathogenic, low penetrance	rs2512600587	RCV002306237
Malignant lymphoma, large B-cell, diffuse	Benign	rs7248864	RCV005917207
Malignant tumor of esophagus	Benign	rs7248864	RCV005917206
Thymoma	Benign	rs7248864	RCV005917208

Show/Hide Text Mining Associations (87)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acute Coronary Syndrome	Inhibit	24107715
Adenomatous Polyposis Coli	Associate	38073344
Atherosclerosis	Associate	17244683, 26372274, 30881601
Autoimmune Diseases	Associate	36466816
Breast Neoplasms	Associate	20132413, 31378902, 36100919, 39796183
Carcinogenesis	Associate	37147883
Carcinoma Hepatocellular	Associate	26336870, 34564989, 36177006, 37386390
Carcinoma Hepatocellular	Inhibit	32318691
Carcinoma Non Small Cell Lung	Inhibit	25501704
Carcinoma Non Small Cell Lung	Associate	35587058
Carcinoma Pancreatic Ductal	Inhibit	26449825
Carcinoma Renal Cell	Associate	35285410
Cerebral Infarction	Associate	30429326
Colitis Ulcerative	Associate	32908909
Colorectal Neoplasms	Associate	32277632
Colorectal Neoplasms	Inhibit	37147883
Common Variable Immunodeficiency	Associate	36466816
Corneal Endothelial Cell Loss	Associate	31750260
Coronary Artery Disease	Associate	30429326
Coronary Disease	Inhibit	22937032
Coronary Disease	Associate	31750260
COVID 19	Inhibit	34253708, 36693535
Crohn Disease	Associate	39346917
Cystic Fibrosis	Inhibit	18218994
Disease	Associate	18218994
Endometrial Neoplasms	Associate	34224334, 37610103
Endometriosis	Associate	36532015
Epiphyseal dysplasia multiple 1	Inhibit	28873368
Fibrosis	Associate	36693535, 37386390
Fuchs' Endothelial Dystrophy	Associate	32127011
Glioma	Associate	30042166
Glomerulonephritis IGA	Associate	38278877
Graft vs Host Disease	Associate	18814951
Heart Diseases	Associate	32727917
Hemangioma Cavernous Central Nervous System	Inhibit	40362576
Hematoma	Inhibit	32848367
Hematoma Subdural Chronic	Associate	32848367
Hemolytic Uremic Syndrome	Inhibit	37795100
Hereditary Breast and Ovarian Cancer Syndrome	Associate	39796183
HIV Infections	Associate	22988032, 26372274
Hyperuricemia	Associate	26299712
Immune System Diseases	Associate	35687490
Infections	Associate	22988032
Inflammation	Associate	16341264, 16455954, 17244683, 18218994, 19957349, 26717516, 28873368, 29996115, 30881601, 32127011, 32848367, 34253708, 34685528, 35695893, 36343116, 37795100 View all (1 more)
Inflammation	Inhibit	20042720, 21167486
Intracranial Arteriovenous Malformations	Associate	29897969
Kidney Failure Chronic	Associate	37795100
Lupus Erythematosus Systemic	Associate	38373841, 39702240
Lymphatic Metastasis	Inhibit	25501704
Lymphoma	Associate	35687490
Lymphoma B Cell Marginal Zone	Associate	25779943, 27335277, 28751561, 36995085, 39313500
Lymphoma Large B Cell Diffuse	Associate	35687490
Lymphoma Non Hodgkin	Associate	28751561
Lymphopenia	Associate	36466816
Mouth Diseases	Associate	35695893
Multiple Myeloma	Associate	26728187, 34635968
Muscular Atrophy	Associate	39354574
Neoplasm Metastasis	Inhibit	26449825, 37147883
Neoplasms	Inhibit	20424164, 25501704, 26449825, 30106140, 30520325, 32318691, 36100919, 37147883
Neoplasms	Associate	25496233, 27195672, 28475008, 31378902, 34642171, 36466816, 37386390
Neuroblastoma	Associate	19495417
Neurodegenerative Diseases	Associate	37269647
Osteoarthritis	Inhibit	28873368
Osteoarthritis Hip	Associate	29944724
Osteoarthritis Knee	Associate	32685450
Ovarian Neoplasms	Associate	31389610
Pancreatic Neoplasms	Inhibit	26449825
Pancreatic Neoplasms	Associate	27644252
Parkinson Disease	Associate	37269647
Periodontitis	Associate	36045361
Polycythemia Vera	Associate	36343116, 38629639
Polypoidal Choroidal Vasculopathy	Associate	35164755
Prostatic Neoplasms	Associate	30520325
Pulmonary Arterial Hypertension	Associate	35346192, 36466816
Pulmonary Disease Chronic Obstructive	Inhibit	18218994
Squamous Cell Carcinoma of Head and Neck	Associate	34741382
Stomach Neoplasms	Associate	28214253, 32016968, 34076999
Thrombocythemia Essential	Associate	36343116
Thrombosis	Associate	16341264, 22937032, 36343116, 40362576
Thyroid Neoplasms	Associate	30106140, 40415364
Tibial Meniscus Injuries	Associate	32685450
Tuberculosis	Associate	34193258, 39922484
Tuberculosis Pulmonary	Associate	39922484
Uremia	Associate	37795100
Urinary Bladder Neoplasms	Associate	29678899
Uterine Cervical Neoplasms	Associate	25119587
Vascular Diseases	Associate	33946046, 34253708

KLF2 (KLF transcription factor 2)