CDO1 (cysteine dioxygenase type 1)

Gene
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1036
Gene name Gene Name - the full gene name approved by the HGNC.
Cysteine dioxygenase type 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CDO1
Synonyms (NCBI Gene) Gene synonyms aliases
CDO-I
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q22.3
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(4)
miRTarBase ID miRNA Experiments Reference
MIRT022885 hsa-miR-124-3p Microarray 18668037
MIRT1961267 hsa-miR-1238 CLIP-seq
MIRT2198008 hsa-miR-548c-3p CLIP-seq
MIRT2198009 hsa-miR-570 CLIP-seq
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
Transcription factor Regulation Reference
MYB Activation 18033314
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(18)
GO ID Ontology Definition Evidence Reference
GO:0000097 Process Sulfur amino acid biosynthetic process TAS 12110289
GO:0005829 Component Cytosol TAS 12110289
GO:0006534 Process Cysteine metabolic process TAS 12110289
GO:0006954 Process Inflammatory response TAS 12110289
GO:0007595 Process Lactation IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
603943 1795 ENSG00000129596
Protein
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q16878
Protein name Cysteine dioxygenase type 1 (EC 1.13.11.20) (Cysteine dioxygenase type I) (CDO) (CDO-I)
Protein function Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.
PDB 2IC1 , 6BGF , 6BGM , 6BPR , 6BPS , 6BPT , 6BPU , 6BPV , 6BPW , 6BPX , 6CDH , 6CDN , 6E87 , 6N42 , 6N43 , 8VL9 , 8VLB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05995 CDO_I 1 → 170 Cysteine dioxygenase type I Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma Hep-G2 cells. {ECO:0000269|PubMed:10427686}.
Sequence
Sequence length 200
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG   Reactome
  Cysteine and methionine metabolism
Taurine and hypotaurine metabolism
Metabolic pathways 		  Degradation of cysteine and homocysteine
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Colorectal cancer Colorectal Carcinoma rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
Diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)		 23665415
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Neurodevelopmental Disorders neurodevelopmental disorder GenCC
Show/Hide Text Mining Associations (37)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 29746493
Adenoma Associate 29746493
Biliary Tract Neoplasms Associate 30325974
Breast Neoplasms Associate 20515469, 22647880, 23630167, 25904753, 26785325, 37740473
Carcinogenesis Associate 24646840
Carcinoma Hepatocellular Associate 24646840, 34255396, 38308276, 39516467
Carcinoma Non Small Cell Lung Associate 32430478, 35793574, 36461127
Carcinoma Pancreatic Ductal Associate 31956659
Carcinoma Renal Cell Associate 25904753
Carcinoma Squamous Cell Associate 22011669