Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
10317
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Beta-1,3-galactosyltransferase 5 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
B3GALT5 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
B3GalT-V, B3GalTx, B3T5, GLCT5, beta-1,3-GalTase 5, beta-3-Gx-T5, beta3Gal-T5 |
Chromosome
Chromosome number
|
21 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
21q22.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of a family of membrane-bound glycoproteins. The encoded protein may synthesize type 1 Lewis antigens, which are elevated in gastrointestinal and pancreatic cancers. Alternatively spliced transcript variants using multiple alter |
UniProt ID |
Q9Y2C3
|
Protein name |
Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) |
Protein function |
Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. {ECO:0000269|PubMed:10406968, ECO:0000269|PubMed:1083746 |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF01762
|
Galactosyl_T |
71 → 261 |
Galactosyltransferase |
Family |
|
Tissue specificity |
TISSUE SPECIFICITY: Expressed in stomach, jejunum, colon, pancreas, small intestine, testis and gastrointestinal and pancreatic cancer cell lines. Hardly detected in lung, liver, adrenal gland and peripheral blood leukocytes. {ECO:0000269|PubMed:10406968} |
Sequence |
|
Sequence length |
310 |
Interactions |
View interactions
|