Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10317
Gene name Gene Name - the full gene name approved by the HGNC.
Beta-1,3-galactosyltransferase 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
B3GALT5
Synonyms (NCBI Gene) Gene synonyms aliases
B3GalT-V, B3GalTx, B3T5, GLCT5, beta-1,3-GalTase 5, beta-3-Gx-T5, beta3Gal-T5
Chromosome Chromosome number
21
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
21q22.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of a family of membrane-bound glycoproteins. The encoded protein may synthesize type 1 Lewis antigens, which are elevated in gastrointestinal and pancreatic cancers. Alternatively spliced transcript variants using multiple alter
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT615471 hsa-miR-329-3p HITS-CLIP 23313552
MIRT615470 hsa-miR-362-3p HITS-CLIP 23313552
MIRT610222 hsa-miR-603 HITS-CLIP 23313552
MIRT610221 hsa-miR-622 HITS-CLIP 23313552
MIRT527913 hsa-miR-4682 HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005783 Component Endoplasmic reticulum HDA 16780588
GO:0005794 Component Golgi apparatus HDA 16780588
GO:0005794 Component Golgi apparatus IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604066 920 ENSG00000183778
Protein
UniProt ID Q9Y2C3
Protein name Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5)
Protein function Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. {ECO:0000269|PubMed:10406968, ECO:0000269|PubMed:1083746
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01762 Galactosyl_T 71 261 Galactosyltransferase Family
Tissue specificity TISSUE SPECIFICITY: Expressed in stomach, jejunum, colon, pancreas, small intestine, testis and gastrointestinal and pancreatic cancer cell lines. Hardly detected in lung, liver, adrenal gland and peripheral blood leukocytes. {ECO:0000269|PubMed:10406968}
Sequence
Sequence length 310
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Glycosphingolipid biosynthesis - lacto and neolacto series
Glycosphingolipid biosynthesis - globo and isoglobo series
Metabolic pathways
  Lewis blood group biosynthesis
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Unknown
Disease term Disease name Evidence References Source
Gout Gout GWAS
Asthma Asthma GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 10406968, 31116002
Breast Neoplasms Associate 30808745
Carcinoma Hepatocellular Associate 28883415, 36495345
Colorectal Neoplasms Associate 31116002
Neoplasms Associate 10212226, 30808745
Pancreatitis Associate 31177837
Pancreatitis Inhibit 31177837