Gene Gene information from NCBI Gene database.
Entrez ID 10317
Gene name Beta-1,3-galactosyltransferase 5
Gene symbol B3GALT5
Synonyms (NCBI Gene)
B3GalT-VB3GalTxB3T5GLCT5beta-13-GalTase 5beta-3-Gx-T5beta3Gal-T5
Chromosome 21
Chromosome location 21q22.2
Summary This gene encodes a member of a family of membrane-bound glycoproteins. The encoded protein may synthesize type 1 Lewis antigens, which are elevated in gastrointestinal and pancreatic cancers. Alternatively spliced transcript variants using multiple alter
miRNA miRNA information provided by mirtarbase database.
966
miRTarBase ID miRNA Experiments Reference
MIRT615471 hsa-miR-329-3p HITS-CLIP 23313552
MIRT615470 hsa-miR-362-3p HITS-CLIP 23313552
MIRT610222 hsa-miR-603 HITS-CLIP 23313552
MIRT610221 hsa-miR-622 HITS-CLIP 23313552
MIRT527913 hsa-miR-4682 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IBA
GO:0000139 Component Golgi membrane IEA
GO:0000139 Component Golgi membrane TAS
GO:0005515 Function Protein binding IPI 32296183
GO:0005783 Component Endoplasmic reticulum HDA 16780588
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604066 920 ENSG00000183778
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y2C3
Protein name Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5)
Protein function Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor. {ECO:0000269|PubMed:10406968, ECO:0000269|PubMed:1083746
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01762 Galactosyl_T 71 261 Galactosyltransferase Family
Tissue specificity TISSUE SPECIFICITY: Expressed in stomach, jejunum, colon, pancreas, small intestine, testis and gastrointestinal and pancreatic cancer cell lines. Hardly detected in lung, liver, adrenal gland and peripheral blood leukocytes. {ECO:0000269|PubMed:10406968}
Sequence
Sequence length 310
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Glycosphingolipid biosynthesis - lacto and neolacto series
Glycosphingolipid biosynthesis - globo and isoglobo series
Metabolic pathways
  Lewis blood group biosynthesis