SF3A1 (splicing factor 3a subunit 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10291 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Splicing factor 3a subunit 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SF3A1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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PRP21, PRPF21, SAP114, SF3A120 |
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Chromosome
Chromosome number
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22 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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22q12.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in splice |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||
| UniProt ID | Q15459 | |||||||||||||||||||||||||
| Protein name | Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) | |||||||||||||||||||||||||
| Protein function | Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:10882114, PubMed:11533230, PubMed:32494006). The 17S U2 SnRNP complex (1) directly participates i | |||||||||||||||||||||||||
| PDB | 1ZKH , 2DT6 , 2DT7 , 5Z56 , 5Z57 , 5Z58 , 6AH0 , 6AHD , 6FF7 , 6QX9 , 6Y53 , 6Y5Q , 7ABG , 7ABI , 7EVO , 7P08 , 7P0V , 7VH9 , 7VPX , 8CH6 , 8H6E , 8H6J , 8H6K , 8H6L , 8HK1 , 8I0P , 8I0R , 8I0S , 8I0T , 8ID2 , 8Q7N , 8QO9 , 8QOZ , 8QP8 , 8QP9 , 8QPA , 8QPB , 8QPE , 8QPK , 8QXD , 8QZS , 8R08 , 8R09 , 8R0A , 8R0B , 8RM5 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:7489498}. | |||||||||||||||||||||||||
| Sequence |
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| Sequence length | 793 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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