| GO ID |
Ontology |
Definition |
Evidence |
Reference |
| GO:0000389 |
Process |
MRNA 3'-splice site recognition |
TAS |
15647371 |
| GO:0000398 |
Process |
MRNA splicing, via spliceosome |
IC |
9731529, 11991638 |
| GO:0000398 |
Process |
MRNA splicing, via spliceosome |
IDA |
10882114, 29360106, 32494006, 36797247 |
| GO:0000398 |
Process |
MRNA splicing, via spliceosome |
IEA |
|
| GO:0000398 |
Process |
MRNA splicing, via spliceosome |
NAS |
21349847, 31744343 |
| GO:0003723 |
Function |
RNA binding |
HDA |
22658674, 22681889 |
| GO:0003723 |
Function |
RNA binding |
IBA |
|
| GO:0003723 |
Function |
RNA binding |
IDA |
10882114 |
| GO:0003723 |
Function |
RNA binding |
IEA |
|
| GO:0005515 |
Function |
Protein binding |
IPI |
10976766, 17098193, 17332742, 20562859, 22365833, 23793891, 26420826, 28514442, 30021884, 33961781, 35271311 |
| GO:0005634 |
Component |
Nucleus |
IDA |
10882114, 21349847, 29360106 |
| GO:0005634 |
Component |
Nucleus |
IEA |
|
| GO:0005634 |
Component |
Nucleus |
NAS |
31744343 |
| GO:0005654 |
Component |
Nucleoplasm |
IDA |
|
| GO:0005654 |
Component |
Nucleoplasm |
TAS |
|
| GO:0005681 |
Component |
Spliceosomal complex |
IDA |
9731529 |
| GO:0005681 |
Component |
Spliceosomal complex |
IEA |
|
| GO:0005681 |
Component |
Spliceosomal complex |
NAS |
31744343 |
| GO:0005684 |
Component |
U2-type spliceosomal complex |
IDA |
10882114, 32494006, 36797247 |
| GO:0005684 |
Component |
U2-type spliceosomal complex |
IPI |
10882114 |
| GO:0005686 |
Component |
U2 snRNP |
IBA |
|
| GO:0005686 |
Component |
U2 snRNP |
IDA |
10882114, 11533230, 23793891 |
| GO:0005686 |
Component |
U2 snRNP |
IEA |
|
| GO:0005686 |
Component |
U2 snRNP |
NAS |
31744343 |
| GO:0006396 |
Process |
RNA processing |
IEA |
|
| GO:0006397 |
Process |
MRNA processing |
IEA |
|
| GO:0006397 |
Process |
MRNA processing |
IMP |
15647371 |
| GO:0008380 |
Process |
RNA splicing |
IEA |
|
| GO:0016607 |
Component |
Nuclear speck |
IDA |
21349847 |
| GO:0016607 |
Component |
Nuclear speck |
IEA |
|
| GO:0045292 |
Process |
MRNA cis splicing, via spliceosome |
IEA |
|
| GO:0071004 |
Component |
U2-type prespliceosome |
IBA |
|
| GO:0071004 |
Component |
U2-type prespliceosome |
IDA |
10882114 |
| GO:0071005 |
Component |
U2-type precatalytic spliceosome |
IDA |
10882114, 29360106 |
| GO:0071013 |
Component |
Catalytic step 2 spliceosome |
IBA |
|
| GO:0071013 |
Component |
Catalytic step 2 spliceosome |
IDA |
11991638 |
| GO:1903241 |
Process |
U2-type prespliceosome assembly |
IDA |
10882114, 11533230 |
| GO:1903241 |
Process |
U2-type prespliceosome assembly |
NAS |
31744343 |
|
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q15459 |
| Protein name |
Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) |
| Protein function |
Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:10882114, PubMed:11533230, PubMed:32494006). The 17S U2 SnRNP complex (1) directly participates i |
| PDB |
1ZKH
, 2DT6
, 2DT7
, 5Z56
, 5Z57
, 5Z58
, 6AH0
, 6AHD
, 6FF7
, 6QX9
, 6Y53
, 6Y5Q
, 7ABG
, 7ABI
, 7EVO
, 7P08
, 7P0V
, 7VH9
, 7VPX
, 8CH6
, 8H6E
, 8H6J
, 8H6K
, 8H6L
, 8HK1
, 8I0P
, 8I0R
, 8I0S
, 8I0T
, 8ID2
, 8Q7N
, 8QO9
, 8QOZ
, 8QP8
, 8QP9
, 8QPA
, 8QPB
, 8QPE
, 8QPK
, 8QXD
, 8QZS
, 8R08
, 8R09
, 8R0A
, 8R0B
, 8RM5
|
| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
| PF01805 |
Surp |
50 → 101 |
Surp module |
Family |
| PF01805 |
Surp |
164 → 215 |
Surp module |
Family |
| PF12230 |
PRP21_like_P |
232 → 472 |
Pre-mRNA splicing factor PRP21 like protein |
Family |
| PF00240 |
ubiquitin |
709 → 788 |
Ubiquitin family |
Domain |
|
| Tissue specificity |
TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:7489498}. |
| Sequence |
|
| Sequence length |
793 |
| Interactions |
View interactions |