Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10286
Gene name Gene Name - the full gene name approved by the HGNC.	BCAS2 pre-mRNA processing factor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	BCAS2
Synonyms (NCBI Gene) Gene synonyms aliases	DAM1, SPF27, Snt309
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p13.2

Show/Hide all(274)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031526	hsa-miR-16-5p	Proteomics	18668040
MIRT722403	hsa-miR-2052	HITS-CLIP	19536157
MIRT722404	hsa-miR-19a-5p	HITS-CLIP	19536157
MIRT722402	hsa-miR-19b-1-5p	HITS-CLIP	19536157
MIRT722401	hsa-miR-19b-2-5p	HITS-CLIP	19536157
MIRT722399	hsa-miR-4273	HITS-CLIP	19536157
MIRT722400	hsa-miR-7156-5p	HITS-CLIP	19536157
MIRT722398	hsa-miR-4677-5p	HITS-CLIP	19536157
MIRT722396	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT722397	hsa-miR-375	HITS-CLIP	19536157
MIRT722395	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT639410	hsa-miR-3943	HITS-CLIP	23824327
MIRT639409	hsa-miR-4690-3p	HITS-CLIP	23824327
MIRT639408	hsa-miR-5685	HITS-CLIP	23824327
MIRT639407	hsa-miR-5193	HITS-CLIP	23824327
MIRT639406	hsa-miR-4469	HITS-CLIP	23824327
MIRT639405	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT441115	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT441115	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT722403	hsa-miR-2052	HITS-CLIP	19536157
MIRT722404	hsa-miR-19a-5p	HITS-CLIP	19536157
MIRT722402	hsa-miR-19b-1-5p	HITS-CLIP	19536157
MIRT722401	hsa-miR-19b-2-5p	HITS-CLIP	19536157
MIRT722399	hsa-miR-4273	HITS-CLIP	19536157
MIRT722400	hsa-miR-7156-5p	HITS-CLIP	19536157
MIRT722398	hsa-miR-4677-5p	HITS-CLIP	19536157
MIRT722396	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT722397	hsa-miR-375	HITS-CLIP	19536157
MIRT722395	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT639410	hsa-miR-3943	HITS-CLIP	23824327
MIRT639409	hsa-miR-4690-3p	HITS-CLIP	23824327
MIRT639408	hsa-miR-5685	HITS-CLIP	23824327
MIRT639407	hsa-miR-5193	HITS-CLIP	23824327
MIRT639406	hsa-miR-4469	HITS-CLIP	23824327
MIRT639405	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT817610	hsa-miR-106a	CLIP-seq
MIRT817611	hsa-miR-106b	CLIP-seq
MIRT817612	hsa-miR-1267	CLIP-seq
MIRT817613	hsa-miR-135a	CLIP-seq
MIRT817614	hsa-miR-135b	CLIP-seq
MIRT817615	hsa-miR-17	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817617	hsa-miR-20a	CLIP-seq
MIRT817618	hsa-miR-20b	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817621	hsa-miR-300	CLIP-seq
MIRT817622	hsa-miR-3065-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT817624	hsa-miR-3163	CLIP-seq
MIRT817625	hsa-miR-338-5p	CLIP-seq
MIRT817626	hsa-miR-3609	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT817628	hsa-miR-3647-3p	CLIP-seq
MIRT817629	hsa-miR-3675-3p	CLIP-seq
MIRT817630	hsa-miR-381	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817633	hsa-miR-410	CLIP-seq
MIRT817634	hsa-miR-425	CLIP-seq
MIRT817635	hsa-miR-4255	CLIP-seq
MIRT817636	hsa-miR-4263	CLIP-seq
MIRT817637	hsa-miR-4282	CLIP-seq
MIRT817638	hsa-miR-4291	CLIP-seq
MIRT817639	hsa-miR-4305	CLIP-seq
MIRT817640	hsa-miR-4477a	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT817643	hsa-miR-4666-3p	CLIP-seq
MIRT817644	hsa-miR-4666-5p	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT817646	hsa-miR-4753-3p	CLIP-seq
MIRT817647	hsa-miR-4778-5p	CLIP-seq
MIRT817648	hsa-miR-4795-3p	CLIP-seq
MIRT817649	hsa-miR-4796-3p	CLIP-seq
MIRT817650	hsa-miR-4799-5p	CLIP-seq
MIRT817651	hsa-miR-486-5p	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817653	hsa-miR-513a-3p	CLIP-seq
MIRT817654	hsa-miR-519d	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817658	hsa-miR-548ah	CLIP-seq
MIRT817659	hsa-miR-548c-3p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817662	hsa-miR-576-5p	CLIP-seq
MIRT817663	hsa-miR-642b	CLIP-seq
MIRT817664	hsa-miR-653	CLIP-seq
MIRT817665	hsa-miR-656	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq
MIRT817668	hsa-miR-93	CLIP-seq
MIRT1941738	hsa-miR-1208	CLIP-seq
MIRT1941739	hsa-miR-1245b-3p	CLIP-seq
MIRT1941740	hsa-miR-1261	CLIP-seq
MIRT1941741	hsa-miR-140-3p	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT1941742	hsa-miR-3189-3p	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT1941743	hsa-miR-362-5p	CLIP-seq
MIRT1941744	hsa-miR-382	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT1941745	hsa-miR-3942-3p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817637	hsa-miR-4282	CLIP-seq
MIRT817640	hsa-miR-4477a	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT1941746	hsa-miR-4661-3p	CLIP-seq
MIRT817644	hsa-miR-4666-5p	CLIP-seq
MIRT1941747	hsa-miR-4670-3p	CLIP-seq
MIRT1941748	hsa-miR-4704-3p	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT1941749	hsa-miR-4762-3p	CLIP-seq
MIRT817651	hsa-miR-486-5p	CLIP-seq
MIRT1941750	hsa-miR-488	CLIP-seq
MIRT1941751	hsa-miR-500b	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817653	hsa-miR-513a-3p	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817664	hsa-miR-653	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq
MIRT817622	hsa-miR-3065-3p	CLIP-seq
MIRT817633	hsa-miR-410	CLIP-seq
MIRT817638	hsa-miR-4291	CLIP-seq
MIRT817640	hsa-miR-4477a	CLIP-seq
MIRT1941739	hsa-miR-1245b-3p	CLIP-seq
MIRT817612	hsa-miR-1267	CLIP-seq
MIRT817613	hsa-miR-135a	CLIP-seq
MIRT817614	hsa-miR-135b	CLIP-seq
MIRT1941741	hsa-miR-140-3p	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817621	hsa-miR-300	CLIP-seq
MIRT2483915	hsa-miR-3121-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT817624	hsa-miR-3163	CLIP-seq
MIRT817625	hsa-miR-338-5p	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT817630	hsa-miR-381	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT1941745	hsa-miR-3942-3p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817639	hsa-miR-4305	CLIP-seq
MIRT2483916	hsa-miR-4509	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT817643	hsa-miR-4666-3p	CLIP-seq
MIRT2483917	hsa-miR-4744	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT817647	hsa-miR-4778-5p	CLIP-seq
MIRT2483918	hsa-miR-4793-5p	CLIP-seq
MIRT817648	hsa-miR-4795-3p	CLIP-seq
MIRT817650	hsa-miR-4799-5p	CLIP-seq
MIRT1941750	hsa-miR-488	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817659	hsa-miR-548c-3p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817663	hsa-miR-642b	CLIP-seq
MIRT817665	hsa-miR-656	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq
MIRT1941739	hsa-miR-1245b-3p	CLIP-seq
MIRT817612	hsa-miR-1267	CLIP-seq
MIRT817613	hsa-miR-135a	CLIP-seq
MIRT817614	hsa-miR-135b	CLIP-seq
MIRT1941741	hsa-miR-140-3p	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817621	hsa-miR-300	CLIP-seq
MIRT2483915	hsa-miR-3121-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT817624	hsa-miR-3163	CLIP-seq
MIRT817625	hsa-miR-338-5p	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT817630	hsa-miR-381	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT1941745	hsa-miR-3942-3p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817636	hsa-miR-4263	CLIP-seq
MIRT817639	hsa-miR-4305	CLIP-seq
MIRT2483916	hsa-miR-4509	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT817643	hsa-miR-4666-3p	CLIP-seq
MIRT2483917	hsa-miR-4744	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT817647	hsa-miR-4778-5p	CLIP-seq
MIRT2483918	hsa-miR-4793-5p	CLIP-seq
MIRT817648	hsa-miR-4795-3p	CLIP-seq
MIRT817650	hsa-miR-4799-5p	CLIP-seq
MIRT1941750	hsa-miR-488	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817659	hsa-miR-548c-3p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817662	hsa-miR-576-5p	CLIP-seq
MIRT817663	hsa-miR-642b	CLIP-seq
MIRT817665	hsa-miR-656	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
ESRRB	Unknown	24667650

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000375	Process	RNA splicing, via transesterification reactions	TAS	9731529
GO:0000380	Process	Alternative mRNA splicing, via spliceosome	IEA
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	28076346
GO:0000398	Process	MRNA splicing, via spliceosome	NAS	23742842
GO:0000974	Component	Prp19 complex	IBA
GO:0000974	Component	Prp19 complex	IEA
GO:0000974	Component	Prp19 complex	IPI	20176811
GO:0001541	Process	Ovarian follicle development	IEA
GO:0005515	Function	Protein binding	IPI	20176811, 20467437, 22365833, 25416956, 27107012, 28514442, 30021884, 31515488, 32296183, 32814053, 33961781, 35271311
GO:0005634	Component	Nucleus	IDA	28076346
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005662	Component	DNA replication factor A complex	IDA	24332808
GO:0005681	Component	Spliceosomal complex	IDA	12169396
GO:0005681	Component	Spliceosomal complex	IEA
GO:0005730	Component	Nucleolus	IEA
GO:0005813	Component	Centrosome	IDA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0008380	Process	RNA splicing	TAS	9731529
GO:0016607	Component	Nuclear speck	IDA
GO:0030163	Process	Protein catabolic process	IEA
GO:0048477	Process	Oogenesis	IEA
GO:0048599	Process	Oocyte development	IEA
GO:0051225	Process	Spindle assembly	IEA
GO:0071007	Component	U2-type catalytic step 2 spliceosome	IDA	28076346
GO:0071013	Component	Catalytic step 2 spliceosome	IBA

MIM	HGNC	e!Ensembl
605783	975	ENSG00000116752

Protein

UniProt ID

O75934

Protein name

Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)

Protein function

Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28076346, PubMed:28502770, PubMed:29301961, PubMed:29360106, PubMed:30705154). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome a

PDB

5MQF , 5XJC , 5YZG , 5Z56 , 5Z57 , 6FF7 , 6ICZ , 6ID0 , 6ID1 , 6QDV , 7A5P , 7W59 , 7W5A , 7W5B , 8C6J , 8CH6 , 8I0T , 8I0U , 8I0V , 8I0W , 8RO2 , 9FMD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05700	BCAS2	11 → 216	Breast carcinoma amplified sequence 2 (BCAS2)	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:10403562}.

Sequence

MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSA
FETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVR
IENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLRE
MESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Sequence length

225

Interactions

View interactions

	KEGG		Reactome
	Spliceosome		mRNA Splicing - Major Pathway

BCAS2 (BCAS2 pre-mRNA processing factor)