Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10286
Gene name Gene Name - the full gene name approved by the HGNC.	BCAS2 pre-mRNA processing factor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	BCAS2
Synonyms (NCBI Gene) Gene synonyms aliases	DAM1, SPF27, Snt309
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p13.2

Show/Hide all(274)

miRTarBase ID	miRNA	Experiments	Reference
MIRT031526	hsa-miR-16-5p	Proteomics	18668040
MIRT722403	hsa-miR-2052	HITS-CLIP	19536157
MIRT722404	hsa-miR-19a-5p	HITS-CLIP	19536157
MIRT722402	hsa-miR-19b-1-5p	HITS-CLIP	19536157
MIRT722401	hsa-miR-19b-2-5p	HITS-CLIP	19536157
MIRT722399	hsa-miR-4273	HITS-CLIP	19536157
MIRT722400	hsa-miR-7156-5p	HITS-CLIP	19536157
MIRT722398	hsa-miR-4677-5p	HITS-CLIP	19536157
MIRT722396	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT722397	hsa-miR-375	HITS-CLIP	19536157
MIRT722395	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT639410	hsa-miR-3943	HITS-CLIP	23824327
MIRT639409	hsa-miR-4690-3p	HITS-CLIP	23824327
MIRT639408	hsa-miR-5685	HITS-CLIP	23824327
MIRT639407	hsa-miR-5193	HITS-CLIP	23824327
MIRT639406	hsa-miR-4469	HITS-CLIP	23824327
MIRT639405	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT441115	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT441115	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT722403	hsa-miR-2052	HITS-CLIP	19536157
MIRT722404	hsa-miR-19a-5p	HITS-CLIP	19536157
MIRT722402	hsa-miR-19b-1-5p	HITS-CLIP	19536157
MIRT722401	hsa-miR-19b-2-5p	HITS-CLIP	19536157
MIRT722399	hsa-miR-4273	HITS-CLIP	19536157
MIRT722400	hsa-miR-7156-5p	HITS-CLIP	19536157
MIRT722398	hsa-miR-4677-5p	HITS-CLIP	19536157
MIRT722396	hsa-miR-4652-3p	HITS-CLIP	19536157
MIRT722397	hsa-miR-375	HITS-CLIP	19536157
MIRT722395	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT639410	hsa-miR-3943	HITS-CLIP	23824327
MIRT639409	hsa-miR-4690-3p	HITS-CLIP	23824327
MIRT639408	hsa-miR-5685	HITS-CLIP	23824327
MIRT639407	hsa-miR-5193	HITS-CLIP	23824327
MIRT639406	hsa-miR-4469	HITS-CLIP	23824327
MIRT639405	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	20371350
MIRT504238	hsa-miR-1272	PAR-CLIP	20371350
MIRT504237	hsa-miR-1322	PAR-CLIP	20371350
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	20371350
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT504239	hsa-miR-580-5p	PAR-CLIP	23446348
MIRT504238	hsa-miR-1272	PAR-CLIP	23446348
MIRT504237	hsa-miR-1322	PAR-CLIP	23446348
MIRT504236	hsa-miR-3682-3p	PAR-CLIP	23446348
MIRT817610	hsa-miR-106a	CLIP-seq
MIRT817611	hsa-miR-106b	CLIP-seq
MIRT817612	hsa-miR-1267	CLIP-seq
MIRT817613	hsa-miR-135a	CLIP-seq
MIRT817614	hsa-miR-135b	CLIP-seq
MIRT817615	hsa-miR-17	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817617	hsa-miR-20a	CLIP-seq
MIRT817618	hsa-miR-20b	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817621	hsa-miR-300	CLIP-seq
MIRT817622	hsa-miR-3065-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT817624	hsa-miR-3163	CLIP-seq
MIRT817625	hsa-miR-338-5p	CLIP-seq
MIRT817626	hsa-miR-3609	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT817628	hsa-miR-3647-3p	CLIP-seq
MIRT817629	hsa-miR-3675-3p	CLIP-seq
MIRT817630	hsa-miR-381	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817633	hsa-miR-410	CLIP-seq
MIRT817634	hsa-miR-425	CLIP-seq
MIRT817635	hsa-miR-4255	CLIP-seq
MIRT817636	hsa-miR-4263	CLIP-seq
MIRT817637	hsa-miR-4282	CLIP-seq
MIRT817638	hsa-miR-4291	CLIP-seq
MIRT817639	hsa-miR-4305	CLIP-seq
MIRT817640	hsa-miR-4477a	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT817643	hsa-miR-4666-3p	CLIP-seq
MIRT817644	hsa-miR-4666-5p	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT817646	hsa-miR-4753-3p	CLIP-seq
MIRT817647	hsa-miR-4778-5p	CLIP-seq
MIRT817648	hsa-miR-4795-3p	CLIP-seq
MIRT817649	hsa-miR-4796-3p	CLIP-seq
MIRT817650	hsa-miR-4799-5p	CLIP-seq
MIRT817651	hsa-miR-486-5p	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817653	hsa-miR-513a-3p	CLIP-seq
MIRT817654	hsa-miR-519d	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817658	hsa-miR-548ah	CLIP-seq
MIRT817659	hsa-miR-548c-3p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817662	hsa-miR-576-5p	CLIP-seq
MIRT817663	hsa-miR-642b	CLIP-seq
MIRT817664	hsa-miR-653	CLIP-seq
MIRT817665	hsa-miR-656	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq
MIRT817668	hsa-miR-93	CLIP-seq
MIRT1941738	hsa-miR-1208	CLIP-seq
MIRT1941739	hsa-miR-1245b-3p	CLIP-seq
MIRT1941740	hsa-miR-1261	CLIP-seq
MIRT1941741	hsa-miR-140-3p	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT1941742	hsa-miR-3189-3p	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT1941743	hsa-miR-362-5p	CLIP-seq
MIRT1941744	hsa-miR-382	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT1941745	hsa-miR-3942-3p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817637	hsa-miR-4282	CLIP-seq
MIRT817640	hsa-miR-4477a	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT1941746	hsa-miR-4661-3p	CLIP-seq
MIRT817644	hsa-miR-4666-5p	CLIP-seq
MIRT1941747	hsa-miR-4670-3p	CLIP-seq
MIRT1941748	hsa-miR-4704-3p	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT1941749	hsa-miR-4762-3p	CLIP-seq
MIRT817651	hsa-miR-486-5p	CLIP-seq
MIRT1941750	hsa-miR-488	CLIP-seq
MIRT1941751	hsa-miR-500b	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817653	hsa-miR-513a-3p	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817664	hsa-miR-653	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq
MIRT817622	hsa-miR-3065-3p	CLIP-seq
MIRT817633	hsa-miR-410	CLIP-seq
MIRT817638	hsa-miR-4291	CLIP-seq
MIRT817640	hsa-miR-4477a	CLIP-seq
MIRT1941739	hsa-miR-1245b-3p	CLIP-seq
MIRT817612	hsa-miR-1267	CLIP-seq
MIRT817613	hsa-miR-135a	CLIP-seq
MIRT817614	hsa-miR-135b	CLIP-seq
MIRT1941741	hsa-miR-140-3p	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817621	hsa-miR-300	CLIP-seq
MIRT2483915	hsa-miR-3121-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT817624	hsa-miR-3163	CLIP-seq
MIRT817625	hsa-miR-338-5p	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT817630	hsa-miR-381	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT1941745	hsa-miR-3942-3p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817639	hsa-miR-4305	CLIP-seq
MIRT2483916	hsa-miR-4509	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT817643	hsa-miR-4666-3p	CLIP-seq
MIRT2483917	hsa-miR-4744	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT817647	hsa-miR-4778-5p	CLIP-seq
MIRT2483918	hsa-miR-4793-5p	CLIP-seq
MIRT817648	hsa-miR-4795-3p	CLIP-seq
MIRT817650	hsa-miR-4799-5p	CLIP-seq
MIRT1941750	hsa-miR-488	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817659	hsa-miR-548c-3p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817663	hsa-miR-642b	CLIP-seq
MIRT817665	hsa-miR-656	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq
MIRT1941739	hsa-miR-1245b-3p	CLIP-seq
MIRT817612	hsa-miR-1267	CLIP-seq
MIRT817613	hsa-miR-135a	CLIP-seq
MIRT817614	hsa-miR-135b	CLIP-seq
MIRT1941741	hsa-miR-140-3p	CLIP-seq
MIRT817616	hsa-miR-205	CLIP-seq
MIRT817619	hsa-miR-2113	CLIP-seq
MIRT817620	hsa-miR-2355-3p	CLIP-seq
MIRT817621	hsa-miR-300	CLIP-seq
MIRT2483915	hsa-miR-3121-3p	CLIP-seq
MIRT817623	hsa-miR-3122	CLIP-seq
MIRT817624	hsa-miR-3163	CLIP-seq
MIRT817625	hsa-miR-338-5p	CLIP-seq
MIRT817627	hsa-miR-3611	CLIP-seq
MIRT817630	hsa-miR-381	CLIP-seq
MIRT817631	hsa-miR-3913-5p	CLIP-seq
MIRT1941745	hsa-miR-3942-3p	CLIP-seq
MIRT817632	hsa-miR-3973	CLIP-seq
MIRT817636	hsa-miR-4263	CLIP-seq
MIRT817639	hsa-miR-4305	CLIP-seq
MIRT2483916	hsa-miR-4509	CLIP-seq
MIRT817641	hsa-miR-4659a-3p	CLIP-seq
MIRT817642	hsa-miR-4659b-3p	CLIP-seq
MIRT817643	hsa-miR-4666-3p	CLIP-seq
MIRT2483917	hsa-miR-4744	CLIP-seq
MIRT817645	hsa-miR-4747-5p	CLIP-seq
MIRT817647	hsa-miR-4778-5p	CLIP-seq
MIRT2483918	hsa-miR-4793-5p	CLIP-seq
MIRT817648	hsa-miR-4795-3p	CLIP-seq
MIRT817650	hsa-miR-4799-5p	CLIP-seq
MIRT1941750	hsa-miR-488	CLIP-seq
MIRT817652	hsa-miR-511	CLIP-seq
MIRT817655	hsa-miR-520g	CLIP-seq
MIRT817656	hsa-miR-520h	CLIP-seq
MIRT817657	hsa-miR-532-5p	CLIP-seq
MIRT817659	hsa-miR-548c-3p	CLIP-seq
MIRT817660	hsa-miR-548n	CLIP-seq
MIRT817661	hsa-miR-548t	CLIP-seq
MIRT817662	hsa-miR-576-5p	CLIP-seq
MIRT817663	hsa-miR-642b	CLIP-seq
MIRT817665	hsa-miR-656	CLIP-seq
MIRT817666	hsa-miR-676	CLIP-seq
MIRT817667	hsa-miR-758	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
ESRRB	Unknown	24667650

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000375	Process	RNA splicing, via transesterification reactions	TAS	9731529
GO:0000398	Process	MRNA splicing, via spliceosome	IDA	28076346
GO:0000398	Process	MRNA splicing, via spliceosome	TAS
GO:0000974	Component	Prp19 complex	IBA	21873635
GO:0005515	Function	Protein binding	IPI	20176811, 20467437, 22365833, 25416956, 27107012, 28514442, 30021884, 31515488, 32296183, 32814053
GO:0005634	Component	Nucleus	IDA	28076346
GO:0005654	Component	Nucleoplasm	TAS
GO:0005662	Component	DNA replication factor A complex	IDA	24332808
GO:0005681	Component	Spliceosomal complex	IDA	12169396
GO:0005730	Component	Nucleolus	IEA
GO:0005813	Component	Centrosome	IDA
GO:0008380	Process	RNA splicing	TAS	9731529
GO:0016607	Component	Nuclear speck	IDA
GO:0071007	Component	U2-type catalytic step 2 spliceosome	IDA	28076346
GO:0071013	Component	Catalytic step 2 spliceosome	IBA	21873635

MIM	HGNC	e!Ensembl
605783	975	ENSG00000116752

Protein

UniProt ID

O75934

Protein name

Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)

Protein function

Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28076346, PubMed:28502770, PubMed:29301961, PubMed:29360106, PubMed:30705154). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome a

PDB

5MQF , 5XJC , 5YZG , 5Z56 , 5Z57 , 6FF7 , 6ICZ , 6ID0 , 6ID1 , 6QDV , 7A5P , 7W59 , 7W5A , 7W5B , 8C6J , 8CH6 , 8I0T , 8I0U , 8I0V , 8I0W , 8RO2 , 9FMD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05700	BCAS2	11 → 216	Breast carcinoma amplified sequence 2 (BCAS2)	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:10403562}.

Sequence

MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSA
FETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVR
IENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLRE
MESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF

Sequence length

225

Interactions

View interactions

	KEGG		Reactome
	Spliceosome		mRNA Splicing - Major Pathway

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)
Diffuse lymphoma	Diffuse Large B-Cell Lymphoma	rs121912651, rs121913289, rs121913293, rs878854402, rs869025340, rs1349928568, rs1569115687, rs121913291	27356265

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	24667650, 30813351, 35705040
Carcinoma Non Small Cell Lung	Associate	34663267
Esophageal Neoplasms	Associate	29115564
Leukemia Lymphoma Adult T Cell	Associate	35041720
Neoplasm Metastasis	Associate	29115564
Neoplasms	Associate	30813351, 34663267
Precancerous Conditions	Stimulate	30813351
Prostatic Neoplasms	Stimulate	25461807

BCAS2 (BCAS2 pre-mRNA processing factor)