Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10270
Gene name Gene Name - the full gene name approved by the HGNC.	A-kinase anchoring protein 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	AKAP8
Synonyms (NCBI Gene) Gene synonyms aliases	AKAP 95, AKAP-8, AKAP-95, AKAP95
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19p13.12
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subce

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001654	hsa-let-7b-5p	pSILAC	18668040
MIRT024227	hsa-miR-218-5p	Sequencing	20371350
MIRT032126	hsa-let-7d-5p	Sequencing	20371350
MIRT001654	hsa-let-7b-5p	Proteomics;Other	18668040
MIRT040654	hsa-miR-92b-3p	CLASH	23622248
MIRT551923	hsa-miR-5683	HITS-CLIP	21572407
MIRT518817	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT518816	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT518815	hsa-miR-6504-3p	HITS-CLIP	21572407
MIRT518811	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT518809	hsa-miR-6083	HITS-CLIP	21572407
MIRT518808	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT551941	hsa-miR-1252-3p	PAR-CLIP	20371350
MIRT551939	hsa-miR-3925-5p	PAR-CLIP	20371350
MIRT551940	hsa-miR-3123	PAR-CLIP	20371350
MIRT551938	hsa-miR-4719	PAR-CLIP	20371350
MIRT551937	hsa-miR-146a-5p	PAR-CLIP	20371350
MIRT551936	hsa-miR-146b-5p	PAR-CLIP	20371350
MIRT551935	hsa-miR-7153-5p	PAR-CLIP	20371350
MIRT551934	hsa-let-7a-5p	PAR-CLIP	20371350
MIRT001654	hsa-let-7b-5p	PAR-CLIP	20371350
MIRT551933	hsa-let-7c-5p	PAR-CLIP	20371350
MIRT032126	hsa-let-7d-5p	PAR-CLIP	20371350
MIRT551932	hsa-let-7e-5p	PAR-CLIP	20371350
MIRT551931	hsa-let-7f-5p	PAR-CLIP	20371350
MIRT551930	hsa-let-7g-5p	PAR-CLIP	20371350
MIRT551929	hsa-let-7i-5p	PAR-CLIP	20371350
MIRT551927	hsa-miR-4458	PAR-CLIP	20371350
MIRT551928	hsa-miR-4500	PAR-CLIP	20371350
MIRT551926	hsa-miR-98-5p	PAR-CLIP	20371350
MIRT551925	hsa-miR-202-3p	PAR-CLIP	20371350
MIRT551924	hsa-miR-1303	PAR-CLIP	20371350
MIRT551941	hsa-miR-1252-3p	PAR-CLIP	21572407
MIRT551939	hsa-miR-3925-5p	PAR-CLIP	21572407
MIRT551940	hsa-miR-3123	PAR-CLIP	21572407
MIRT551938	hsa-miR-4719	PAR-CLIP	21572407
MIRT551937	hsa-miR-146a-5p	PAR-CLIP	21572407
MIRT551936	hsa-miR-146b-5p	PAR-CLIP	21572407
MIRT551935	hsa-miR-7153-5p	PAR-CLIP	21572407
MIRT551934	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT001654	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT551933	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT032126	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT551932	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT551931	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT551930	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT551929	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT551927	hsa-miR-4458	PAR-CLIP	21572407
MIRT551928	hsa-miR-4500	PAR-CLIP	21572407
MIRT551926	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT551925	hsa-miR-202-3p	PAR-CLIP	21572407
MIRT551924	hsa-miR-1303	PAR-CLIP	21572407
MIRT551923	hsa-miR-5683	PAR-CLIP	21572407
MIRT518817	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT518816	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT518815	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT518814	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT518813	hsa-miR-1250-3p	PAR-CLIP	21572407
MIRT518812	hsa-miR-153-5p	PAR-CLIP	21572407
MIRT518811	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT518810	hsa-miR-5696	PAR-CLIP	21572407
MIRT291883	hsa-miR-579-3p	PAR-CLIP	21572407
MIRT291887	hsa-miR-664b-3p	PAR-CLIP	21572407
MIRT518809	hsa-miR-6083	PAR-CLIP	21572407
MIRT518808	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT518817	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT518816	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT518815	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT518814	hsa-miR-205-3p	PAR-CLIP	23446348
MIRT518813	hsa-miR-1250-3p	PAR-CLIP	23446348
MIRT518812	hsa-miR-153-5p	PAR-CLIP	23446348
MIRT518811	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT518810	hsa-miR-5696	PAR-CLIP	23446348
MIRT291883	hsa-miR-579-3p	PAR-CLIP	23446348
MIRT291887	hsa-miR-664b-3p	PAR-CLIP	23446348
MIRT518809	hsa-miR-6083	PAR-CLIP	23446348
MIRT518808	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT551923	hsa-miR-5683	HITS-CLIP	21572407
MIRT518817	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT518816	hsa-miR-656-3p	HITS-CLIP	21572407
MIRT518815	hsa-miR-6504-3p	HITS-CLIP	21572407
MIRT518811	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT518809	hsa-miR-6083	HITS-CLIP	21572407
MIRT518808	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT551941	hsa-miR-1252-3p	PAR-CLIP	20371350
MIRT551939	hsa-miR-3925-5p	PAR-CLIP	20371350
MIRT551940	hsa-miR-3123	PAR-CLIP	20371350
MIRT551938	hsa-miR-4719	PAR-CLIP	20371350
MIRT551937	hsa-miR-146a-5p	PAR-CLIP	20371350
MIRT551936	hsa-miR-146b-5p	PAR-CLIP	20371350
MIRT551935	hsa-miR-7153-5p	PAR-CLIP	20371350
MIRT551934	hsa-let-7a-5p	PAR-CLIP	20371350
MIRT001654	hsa-let-7b-5p	PAR-CLIP	20371350
MIRT551933	hsa-let-7c-5p	PAR-CLIP	20371350
MIRT032126	hsa-let-7d-5p	PAR-CLIP	20371350
MIRT551932	hsa-let-7e-5p	PAR-CLIP	20371350
MIRT551931	hsa-let-7f-5p	PAR-CLIP	20371350
MIRT551930	hsa-let-7g-5p	PAR-CLIP	20371350
MIRT551929	hsa-let-7i-5p	PAR-CLIP	20371350
MIRT551927	hsa-miR-4458	PAR-CLIP	20371350
MIRT551928	hsa-miR-4500	PAR-CLIP	20371350
MIRT551926	hsa-miR-98-5p	PAR-CLIP	20371350
MIRT551925	hsa-miR-202-3p	PAR-CLIP	20371350
MIRT551924	hsa-miR-1303	PAR-CLIP	20371350
MIRT551941	hsa-miR-1252-3p	PAR-CLIP	21572407
MIRT551939	hsa-miR-3925-5p	PAR-CLIP	21572407
MIRT551940	hsa-miR-3123	PAR-CLIP	21572407
MIRT551938	hsa-miR-4719	PAR-CLIP	21572407
MIRT551937	hsa-miR-146a-5p	PAR-CLIP	21572407
MIRT551936	hsa-miR-146b-5p	PAR-CLIP	21572407
MIRT551935	hsa-miR-7153-5p	PAR-CLIP	21572407
MIRT551934	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT001654	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT551933	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT032126	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT551932	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT551931	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT551930	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT551929	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT551927	hsa-miR-4458	PAR-CLIP	21572407
MIRT551928	hsa-miR-4500	PAR-CLIP	21572407
MIRT551926	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT551925	hsa-miR-202-3p	PAR-CLIP	21572407
MIRT551924	hsa-miR-1303	PAR-CLIP	21572407
MIRT551923	hsa-miR-5683	PAR-CLIP	21572407
MIRT518817	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT518816	hsa-miR-656-3p	PAR-CLIP	21572407
MIRT518815	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT518814	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT518813	hsa-miR-1250-3p	PAR-CLIP	21572407
MIRT518812	hsa-miR-153-5p	PAR-CLIP	21572407
MIRT518811	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT518810	hsa-miR-5696	PAR-CLIP	21572407
MIRT291883	hsa-miR-579-3p	PAR-CLIP	21572407
MIRT291887	hsa-miR-664b-3p	PAR-CLIP	21572407
MIRT518809	hsa-miR-6083	PAR-CLIP	21572407
MIRT518808	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT518817	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT518816	hsa-miR-656-3p	PAR-CLIP	23446348
MIRT518815	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT518814	hsa-miR-205-3p	PAR-CLIP	23446348
MIRT518813	hsa-miR-1250-3p	PAR-CLIP	23446348
MIRT518812	hsa-miR-153-5p	PAR-CLIP	23446348
MIRT518811	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT518810	hsa-miR-5696	PAR-CLIP	23446348
MIRT291883	hsa-miR-579-3p	PAR-CLIP	23446348
MIRT291887	hsa-miR-664b-3p	PAR-CLIP	23446348
MIRT518809	hsa-miR-6083	PAR-CLIP	23446348
MIRT518808	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT775963	hsa-miR-1273f	CLIP-seq
MIRT775964	hsa-miR-127-5p	CLIP-seq
MIRT775965	hsa-miR-1283	CLIP-seq
MIRT775966	hsa-miR-145	CLIP-seq
MIRT775967	hsa-miR-154	CLIP-seq
MIRT775968	hsa-miR-1825	CLIP-seq
MIRT775969	hsa-miR-183	CLIP-seq
MIRT775970	hsa-miR-193a-5p	CLIP-seq
MIRT775971	hsa-miR-199a-5p	CLIP-seq
MIRT775972	hsa-miR-199b-5p	CLIP-seq
MIRT775973	hsa-miR-3129-3p	CLIP-seq
MIRT775974	hsa-miR-3130-3p	CLIP-seq
MIRT775975	hsa-miR-3180-5p	CLIP-seq
MIRT775976	hsa-miR-3650	CLIP-seq
MIRT775977	hsa-miR-3658	CLIP-seq
MIRT775978	hsa-miR-3929	CLIP-seq
MIRT775979	hsa-miR-431	CLIP-seq
MIRT775980	hsa-miR-4419b	CLIP-seq
MIRT775981	hsa-miR-4455	CLIP-seq
MIRT775982	hsa-miR-4478	CLIP-seq
MIRT775983	hsa-miR-4484	CLIP-seq
MIRT775984	hsa-miR-4536	CLIP-seq
MIRT775985	hsa-miR-4705	CLIP-seq
MIRT775986	hsa-miR-4724-3p	CLIP-seq
MIRT775987	hsa-miR-4735-5p	CLIP-seq
MIRT775988	hsa-miR-4746-3p	CLIP-seq
MIRT775989	hsa-miR-4775	CLIP-seq
MIRT775990	hsa-miR-4781-3p	CLIP-seq
MIRT775991	hsa-miR-4793-3p	CLIP-seq
MIRT775992	hsa-miR-520d-5p	CLIP-seq
MIRT775993	hsa-miR-524-5p	CLIP-seq
MIRT775994	hsa-miR-526b	CLIP-seq
MIRT775995	hsa-miR-548an	CLIP-seq
MIRT775996	hsa-miR-548m	CLIP-seq
MIRT775997	hsa-miR-590-3p	CLIP-seq
MIRT775998	hsa-miR-609	CLIP-seq
MIRT775999	hsa-miR-615-5p	CLIP-seq
MIRT776000	hsa-miR-622	CLIP-seq
MIRT776001	hsa-miR-656	CLIP-seq
MIRT776002	hsa-miR-802	CLIP-seq
MIRT1928987	hsa-miR-1179	CLIP-seq
MIRT1928988	hsa-miR-1229	CLIP-seq
MIRT1928989	hsa-miR-1914	CLIP-seq
MIRT1928990	hsa-miR-197	CLIP-seq
MIRT1928991	hsa-miR-214	CLIP-seq
MIRT1928992	hsa-miR-3183	CLIP-seq
MIRT1928993	hsa-miR-331-5p	CLIP-seq
MIRT1928994	hsa-miR-3545-3p	CLIP-seq
MIRT1928995	hsa-miR-3619-5p	CLIP-seq
MIRT1928996	hsa-miR-378g	CLIP-seq
MIRT1928997	hsa-miR-3918	CLIP-seq
MIRT1928998	hsa-miR-4678	CLIP-seq
MIRT1928999	hsa-miR-4680-5p	CLIP-seq
MIRT1929000	hsa-miR-4720-3p	CLIP-seq
MIRT1929001	hsa-miR-4723-3p	CLIP-seq
MIRT1929002	hsa-miR-586	CLIP-seq
MIRT1929003	hsa-miR-607	CLIP-seq
MIRT1929004	hsa-miR-642b	CLIP-seq
MIRT1929005	hsa-miR-761	CLIP-seq
MIRT1928987	hsa-miR-1179	CLIP-seq
MIRT2169668	hsa-miR-1207-3p	CLIP-seq
MIRT2169669	hsa-miR-1249	CLIP-seq
MIRT2169670	hsa-miR-1267	CLIP-seq
MIRT775963	hsa-miR-1273f	CLIP-seq
MIRT775965	hsa-miR-1283	CLIP-seq
MIRT775970	hsa-miR-193a-5p	CLIP-seq
MIRT1928991	hsa-miR-214	CLIP-seq
MIRT2169671	hsa-miR-224	CLIP-seq
MIRT2169672	hsa-miR-3120-3p	CLIP-seq
MIRT775974	hsa-miR-3130-3p	CLIP-seq
MIRT2169673	hsa-miR-329	CLIP-seq
MIRT2169674	hsa-miR-335	CLIP-seq
MIRT2169675	hsa-miR-34b	CLIP-seq
MIRT1928995	hsa-miR-3619-5p	CLIP-seq
MIRT2169676	hsa-miR-362-3p	CLIP-seq
MIRT775977	hsa-miR-3658	CLIP-seq
MIRT2169677	hsa-miR-3677-5p	CLIP-seq
MIRT2169678	hsa-miR-3691-3p	CLIP-seq
MIRT2169679	hsa-miR-377	CLIP-seq
MIRT1928997	hsa-miR-3918	CLIP-seq
MIRT2169680	hsa-miR-3920	CLIP-seq
MIRT2169681	hsa-miR-4263	CLIP-seq
MIRT775979	hsa-miR-431	CLIP-seq
MIRT2169682	hsa-miR-4435	CLIP-seq
MIRT2169683	hsa-miR-4496	CLIP-seq
MIRT2169684	hsa-miR-4652-3p	CLIP-seq
MIRT2169685	hsa-miR-4717-5p	CLIP-seq
MIRT775986	hsa-miR-4724-3p	CLIP-seq
MIRT2169686	hsa-miR-4738-3p	CLIP-seq
MIRT2169687	hsa-miR-4760-5p	CLIP-seq
MIRT2169688	hsa-miR-4778-5p	CLIP-seq
MIRT775990	hsa-miR-4781-3p	CLIP-seq
MIRT775991	hsa-miR-4793-3p	CLIP-seq
MIRT2169689	hsa-miR-4795-3p	CLIP-seq
MIRT2169690	hsa-miR-519a	CLIP-seq
MIRT2169691	hsa-miR-519b-3p	CLIP-seq
MIRT2169692	hsa-miR-519c-3p	CLIP-seq
MIRT775992	hsa-miR-520d-5p	CLIP-seq
MIRT775993	hsa-miR-524-5p	CLIP-seq
MIRT775994	hsa-miR-526b	CLIP-seq
MIRT775996	hsa-miR-548m	CLIP-seq
MIRT2169693	hsa-miR-576-5p	CLIP-seq
MIRT2169694	hsa-miR-582-5p	CLIP-seq
MIRT1929003	hsa-miR-607	CLIP-seq
MIRT775999	hsa-miR-615-5p	CLIP-seq
MIRT776000	hsa-miR-622	CLIP-seq
MIRT1929004	hsa-miR-642b	CLIP-seq
MIRT2169695	hsa-miR-651	CLIP-seq
MIRT776001	hsa-miR-656	CLIP-seq
MIRT1929005	hsa-miR-761	CLIP-seq
MIRT2169670	hsa-miR-1267	CLIP-seq
MIRT1928991	hsa-miR-214	CLIP-seq
MIRT2472426	hsa-miR-3146	CLIP-seq
MIRT2472427	hsa-miR-3182	CLIP-seq
MIRT1928995	hsa-miR-3619-5p	CLIP-seq
MIRT1928997	hsa-miR-3918	CLIP-seq
MIRT2169680	hsa-miR-3920	CLIP-seq
MIRT2169683	hsa-miR-4496	CLIP-seq
MIRT2472428	hsa-miR-4643	CLIP-seq
MIRT2169684	hsa-miR-4652-3p	CLIP-seq
MIRT2472429	hsa-miR-4659a-3p	CLIP-seq
MIRT2472430	hsa-miR-4659b-3p	CLIP-seq
MIRT2472431	hsa-miR-4762-3p	CLIP-seq
MIRT2169688	hsa-miR-4778-5p	CLIP-seq
MIRT1929003	hsa-miR-607	CLIP-seq
MIRT2472432	hsa-miR-621	CLIP-seq
MIRT1929004	hsa-miR-642b	CLIP-seq
MIRT2169695	hsa-miR-651	CLIP-seq
MIRT1929005	hsa-miR-761	CLIP-seq
MIRT2169670	hsa-miR-1267	CLIP-seq
MIRT1928991	hsa-miR-214	CLIP-seq
MIRT2472427	hsa-miR-3182	CLIP-seq
MIRT1928995	hsa-miR-3619-5p	CLIP-seq
MIRT1928997	hsa-miR-3918	CLIP-seq
MIRT2169680	hsa-miR-3920	CLIP-seq
MIRT2169683	hsa-miR-4496	CLIP-seq
MIRT2169684	hsa-miR-4652-3p	CLIP-seq
MIRT2472429	hsa-miR-4659a-3p	CLIP-seq
MIRT2472430	hsa-miR-4659b-3p	CLIP-seq
MIRT2472431	hsa-miR-4762-3p	CLIP-seq
MIRT2169688	hsa-miR-4778-5p	CLIP-seq
MIRT1929003	hsa-miR-607	CLIP-seq
MIRT1929004	hsa-miR-642b	CLIP-seq
MIRT2169695	hsa-miR-651	CLIP-seq
MIRT1929005	hsa-miR-761	CLIP-seq

Show/Hide all(35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000278	Process	Mitotic cell cycle	TAS	9473338
GO:0000793	Component	Condensed chromosome	IEA
GO:0001939	Component	Female pronucleus	IEA
GO:0002376	Process	Immune system process	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003690	Function	Double-stranded DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	9473338, 12740381, 16227597, 16980585, 22130794, 23995757, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	9473338
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA	26683827
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0007076	Process	Mitotic chromosome condensation	IBA
GO:0007076	Process	Mitotic chromosome condensation	IEA
GO:0007165	Process	Signal transduction	TAS	9473338
GO:0008270	Function	Zinc ion binding	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016363	Component	Nuclear matrix	IBA
GO:0016363	Component	Nuclear matrix	IEA
GO:0016363	Component	Nuclear matrix	ISS
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IEA
GO:0034237	Function	Protein kinase A regulatory subunit binding	IBA
GO:0034237	Function	Protein kinase A regulatory subunit binding	IEA
GO:0034237	Function	Protein kinase A regulatory subunit binding	IPI	17911601
GO:0042826	Function	Histone deacetylase binding	IDA	16980585
GO:0044839	Process	Cell cycle G2/M phase transition	IMP	16980585
GO:0045087	Process	Innate immune response	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0051059	Function	NF-kappaB binding	IEA
GO:0071222	Process	Cellular response to lipopolysaccharide	IEA
GO:0071380	Process	Cellular response to prostaglandin E stimulus	IEA

MIM	HGNC	e!Ensembl
604692	378	ENSG00000105127

Protein

UniProt ID

O43823

Protein name

A-kinase anchor protein 8 (AKAP-8) (A-kinase anchor protein 95 kDa) (AKAP 95)

Protein function

Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II) (PubMed:9473338). Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromo

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04988	AKAP95	415 → 546	A-kinase anchoring protein 95 (AKAP95)	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Expressed in mature dendritic cells. {ECO:0000269|PubMed:19277197}.

Sequence

MDQGYGGYGAWSAGPANTQGAYGTGVASWQGYENYNYYGAQNTSVTTGATYSYGPASWEA
AKANDGGLAAGAPAMHMASYGPEPCTDNSDSLIAKINQRLDMMSKEGGRGGSGGGGEGIQ
DRESSFRFQPFESYDSRPCLPEHNPYRPSYSYDYEFDLGSDRNGSFGGQYSECRDPARER
GSLDGFMRGRGQGRFQDRSNPGTFMRSDPFVPPAASSEPLSTPWNELNYVGGRGLGGPSP
SRPPPSLFSQSMAPDYGVMGMQGAGGYDSTMPYGCGRSQPRMRDRDRPKRRGFDRFGPDG
TGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEK
EDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRF
ISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKETAKPKPDPFKGIGQEHFFKKIEAAH
CLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYL
KGEDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESS
GEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEA
ESAQTRVAPAPAAADAEVEQTDAESKDAVPTE

Sequence length

692

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Long QT Syndrome	long qt syndrome	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Autistic Disorder	Associate	26076356
Breast Neoplasms	Associate	28755423, 32321829
Cleft Lip	Associate	26913922
Colorectal Neoplasms	Associate	36691407
Esophageal Neoplasms	Associate	28771997
Lung Neoplasms	Associate	26880274, 32338437
Lymphatic Metastasis	Associate	36691407
Ovarian Neoplasms	Associate	26823747
Rectal Neoplasms	Associate	25973052

AKAP8 (A-kinase anchoring protein 8)