Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10250
Gene name Gene Name - the full gene name approved by the HGNC.	Serine and arginine repetitive matrix 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SRRM1
Synonyms (NCBI Gene) Gene synonyms aliases	160-KD, POP101, SRM160
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p36.11

Show/Hide all(144)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023485	hsa-miR-1-3p	Proteomics	18668040
MIRT043660	hsa-miR-326	CLASH	23622248
MIRT043025	hsa-miR-324-5p	CLASH	23622248
MIRT036777	hsa-miR-760	CLASH	23622248
MIRT530015	hsa-miR-4282	PAR-CLIP	22012620
MIRT530014	hsa-miR-499a-3p	PAR-CLIP	22012620
MIRT530013	hsa-miR-499b-3p	PAR-CLIP	22012620
MIRT530015	hsa-miR-4282	PAR-CLIP	22012620
MIRT530014	hsa-miR-499a-3p	PAR-CLIP	22012620
MIRT530013	hsa-miR-499b-3p	PAR-CLIP	22012620
MIRT1389781	hsa-miR-105	CLIP-seq
MIRT1389782	hsa-miR-1207-3p	CLIP-seq
MIRT1389783	hsa-miR-1252	CLIP-seq
MIRT1389784	hsa-miR-128	CLIP-seq
MIRT1389785	hsa-miR-1285	CLIP-seq
MIRT1389786	hsa-miR-1323	CLIP-seq
MIRT1389787	hsa-miR-186	CLIP-seq
MIRT1389788	hsa-miR-2113	CLIP-seq
MIRT1389789	hsa-miR-296-5p	CLIP-seq
MIRT1389790	hsa-miR-300	CLIP-seq
MIRT1389791	hsa-miR-3117-5p	CLIP-seq
MIRT1389792	hsa-miR-3138	CLIP-seq
MIRT1389793	hsa-miR-3187-5p	CLIP-seq
MIRT1389794	hsa-miR-3192	CLIP-seq
MIRT1389795	hsa-miR-3199	CLIP-seq
MIRT1389796	hsa-miR-320a	CLIP-seq
MIRT1389797	hsa-miR-320b	CLIP-seq
MIRT1389798	hsa-miR-320c	CLIP-seq
MIRT1389799	hsa-miR-320d	CLIP-seq
MIRT1389800	hsa-miR-3545-5p	CLIP-seq
MIRT1389801	hsa-miR-3646	CLIP-seq
MIRT1389802	hsa-miR-371-5p	CLIP-seq
MIRT1389803	hsa-miR-374c	CLIP-seq
MIRT1389804	hsa-miR-378g	CLIP-seq
MIRT1389805	hsa-miR-381	CLIP-seq
MIRT1389806	hsa-miR-3974	CLIP-seq
MIRT1389807	hsa-miR-4300	CLIP-seq
MIRT1389808	hsa-miR-4314	CLIP-seq
MIRT1389809	hsa-miR-4317	CLIP-seq
MIRT1389810	hsa-miR-4318	CLIP-seq
MIRT1389811	hsa-miR-4429	CLIP-seq
MIRT1389812	hsa-miR-4432	CLIP-seq
MIRT1389813	hsa-miR-4486	CLIP-seq
MIRT1389814	hsa-miR-4495	CLIP-seq
MIRT1389815	hsa-miR-4509	CLIP-seq
MIRT1389816	hsa-miR-450b-5p	CLIP-seq
MIRT1389817	hsa-miR-4536	CLIP-seq
MIRT1389818	hsa-miR-4633-3p	CLIP-seq
MIRT1389819	hsa-miR-4646-5p	CLIP-seq
MIRT1389820	hsa-miR-4652-3p	CLIP-seq
MIRT1389821	hsa-miR-4661-3p	CLIP-seq
MIRT1389822	hsa-miR-4661-5p	CLIP-seq
MIRT1389823	hsa-miR-4694-3p	CLIP-seq
MIRT1389824	hsa-miR-4744	CLIP-seq
MIRT1389825	hsa-miR-4778-5p	CLIP-seq
MIRT1389826	hsa-miR-4800-5p	CLIP-seq
MIRT1389827	hsa-miR-499-5p	CLIP-seq
MIRT1389828	hsa-miR-501-5p	CLIP-seq
MIRT1389829	hsa-miR-507	CLIP-seq
MIRT1389830	hsa-miR-520d-5p	CLIP-seq
MIRT1389831	hsa-miR-522	CLIP-seq
MIRT1389832	hsa-miR-524-5p	CLIP-seq
MIRT1389833	hsa-miR-548o	CLIP-seq
MIRT1389834	hsa-miR-557	CLIP-seq
MIRT1389835	hsa-miR-600	CLIP-seq
MIRT1389836	hsa-miR-605	CLIP-seq
MIRT1389837	hsa-miR-610	CLIP-seq
MIRT1389838	hsa-miR-612	CLIP-seq
MIRT1389839	hsa-miR-624	CLIP-seq
MIRT1389840	hsa-miR-655	CLIP-seq
MIRT1389841	hsa-miR-668	CLIP-seq
MIRT1389842	hsa-miR-888	CLIP-seq
MIRT1389843	hsa-miR-920	CLIP-seq
MIRT1389784	hsa-miR-128	CLIP-seq
MIRT1389785	hsa-miR-1285	CLIP-seq
MIRT2116764	hsa-miR-203	CLIP-seq
MIRT2116765	hsa-miR-214	CLIP-seq
MIRT1389790	hsa-miR-300	CLIP-seq
MIRT1389791	hsa-miR-3117-5p	CLIP-seq
MIRT2116766	hsa-miR-3120-5p	CLIP-seq
MIRT2116767	hsa-miR-3128	CLIP-seq
MIRT2116768	hsa-miR-3160-5p	CLIP-seq
MIRT1389793	hsa-miR-3187-5p	CLIP-seq
MIRT1389800	hsa-miR-3545-5p	CLIP-seq
MIRT2116769	hsa-miR-3619-5p	CLIP-seq
MIRT1389804	hsa-miR-378g	CLIP-seq
MIRT1389805	hsa-miR-381	CLIP-seq
MIRT2116770	hsa-miR-4291	CLIP-seq
MIRT1389808	hsa-miR-4314	CLIP-seq
MIRT2116771	hsa-miR-4470	CLIP-seq
MIRT1389813	hsa-miR-4486	CLIP-seq
MIRT1389814	hsa-miR-4495	CLIP-seq
MIRT1389820	hsa-miR-4652-3p	CLIP-seq
MIRT2116772	hsa-miR-4742-5p	CLIP-seq
MIRT2116773	hsa-miR-4793-5p	CLIP-seq
MIRT2116774	hsa-miR-579	CLIP-seq
MIRT1389838	hsa-miR-612	CLIP-seq
MIRT2116775	hsa-miR-664	CLIP-seq
MIRT2116776	hsa-miR-761	CLIP-seq
MIRT2116777	hsa-miR-922	CLIP-seq
MIRT1389785	hsa-miR-1285	CLIP-seq
MIRT1389786	hsa-miR-1323	CLIP-seq
MIRT1389787	hsa-miR-186	CLIP-seq
MIRT2116765	hsa-miR-214	CLIP-seq
MIRT1389789	hsa-miR-296-5p	CLIP-seq
MIRT1389790	hsa-miR-300	CLIP-seq
MIRT1389791	hsa-miR-3117-5p	CLIP-seq
MIRT2116766	hsa-miR-3120-5p	CLIP-seq
MIRT1389792	hsa-miR-3138	CLIP-seq
MIRT1389793	hsa-miR-3187-5p	CLIP-seq
MIRT1389800	hsa-miR-3545-5p	CLIP-seq
MIRT2116769	hsa-miR-3619-5p	CLIP-seq
MIRT1389803	hsa-miR-374c	CLIP-seq
MIRT1389804	hsa-miR-378g	CLIP-seq
MIRT1389805	hsa-miR-381	CLIP-seq
MIRT2339179	hsa-miR-3908	CLIP-seq
MIRT2339180	hsa-miR-3942-5p	CLIP-seq
MIRT2116770	hsa-miR-4291	CLIP-seq
MIRT2339181	hsa-miR-4313	CLIP-seq
MIRT1389808	hsa-miR-4314	CLIP-seq
MIRT1389810	hsa-miR-4318	CLIP-seq
MIRT1389813	hsa-miR-4486	CLIP-seq
MIRT1389814	hsa-miR-4495	CLIP-seq
MIRT1389816	hsa-miR-450b-5p	CLIP-seq
MIRT1389820	hsa-miR-4652-3p	CLIP-seq
MIRT2339182	hsa-miR-4666-5p	CLIP-seq
MIRT2339183	hsa-miR-4703-5p	CLIP-seq
MIRT2116772	hsa-miR-4742-5p	CLIP-seq
MIRT2116773	hsa-miR-4793-5p	CLIP-seq
MIRT1389826	hsa-miR-4800-5p	CLIP-seq
MIRT2339184	hsa-miR-495	CLIP-seq
MIRT1389829	hsa-miR-507	CLIP-seq
MIRT1389833	hsa-miR-548o	CLIP-seq
MIRT1389834	hsa-miR-557	CLIP-seq
MIRT2116774	hsa-miR-579	CLIP-seq
MIRT1389835	hsa-miR-600	CLIP-seq
MIRT1389836	hsa-miR-605	CLIP-seq
MIRT1389838	hsa-miR-612	CLIP-seq
MIRT1389839	hsa-miR-624	CLIP-seq
MIRT2339185	hsa-miR-653	CLIP-seq
MIRT1389840	hsa-miR-655	CLIP-seq
MIRT1389841	hsa-miR-668	CLIP-seq
MIRT2116776	hsa-miR-761	CLIP-seq
MIRT2116777	hsa-miR-922	CLIP-seq

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000375	Process	RNA splicing, via transesterification reactions	TAS	9531537
GO:0000398	Process	MRNA splicing, via spliceosome	IC	11991638
GO:0000398	Process	MRNA splicing, via spliceosome	TAS
GO:0003677	Function	DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0005515	Function	Protein binding	IPI	25416956, 26871637, 32296183
GO:0005634	Component	Nucleus	TAS	9531537
GO:0005654	Component	Nucleoplasm	TAS
GO:0005829	Component	Cytosol	TAS
GO:0006405	Process	RNA export from nucleus	TAS
GO:0006406	Process	MRNA export from nucleus	TAS
GO:0008380	Process	RNA splicing	TAS	9531537
GO:0016363	Component	Nuclear matrix	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0031124	Process	MRNA 3'-end processing	TAS
GO:0071013	Component	Catalytic step 2 spliceosome	IDA	11991638

MIM	HGNC	e!Ensembl
605975	16638	ENSG00000133226

Protein

UniProt ID

Q8IYB3

Protein name

Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)

Protein function

Part of pre- and post-splicing multiprotein mRNP complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Involved in numerous pre-mRNA processing events. Promotes constitutive and

PDB

1MP1 , 6FF4 , 6FF7 , 7ABG , 7ABH , 7ABI , 7DVQ , 8I0P , 8I0R

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01480	PWI	46 → 117	PWI domain	Family

Sequence

MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEIL
GFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIP
SAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSP
SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATS
TSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR
RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS
SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS
NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ
QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET
SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPI
QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH
RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP
IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNW
SPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAA
AAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQV
SPQS

Sequence length

904

Interactions

View interactions

	KEGG		Reactome
	Nucleocytoplasmic transport mRNA surveillance pathway		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Hypertension	Hypertension	GWAS
Schizophrenia	Schizophrenia	GWAS

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Hepatocellular	Associate	24592541
Hashimoto Disease	Associate	36674671
Neoplasm Metastasis	Associate	31902674
Neoplasms	Associate	16354706
Personality Disorders	Associate	31902674
Prostatic Neoplasms	Associate	31902674

SRRM1 (serine and arginine repetitive matrix 1)