Gene Gene information from NCBI Gene database.
Entrez ID 10228
Gene name Syntaxin 6
Gene symbol STX6
Synonyms (NCBI Gene)
-
Chromosome 1
Chromosome location 1q25.3
miRNA miRNA information provided by mirtarbase database.
1161
miRTarBase ID miRNA Experiments Reference
MIRT019742 hsa-miR-375 Microarray 20215506
MIRT719702 hsa-miR-4308 HITS-CLIP 19536157
MIRT719701 hsa-miR-4292 HITS-CLIP 19536157
MIRT719700 hsa-miR-6791-5p HITS-CLIP 19536157
MIRT719699 hsa-miR-130b-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
55
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0000139 Component Golgi membrane TAS
GO:0000149 Function SNARE binding IBA
GO:0005484 Function SNAP receptor activity IBA
GO:0005484 Function SNAP receptor activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603944 11441 ENSG00000135823
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O43752
Protein name Syntaxin-6
Protein function SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to th
PDB 2NPS , 4J2C
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF09177 Syntaxin-6_N 5 103 Syntaxin 6, N-terminal Domain
PF05739 SNARE 199 251 SNARE domain Family
Sequence
MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMK
DQMSTSSVQALAERKNR
QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
LFAVLLVVLIL
FLVL
Sequence length 255
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  SNARE interactions in vesicular transport   Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network