Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10226
Gene name Gene Name - the full gene name approved by the HGNC.
Perilipin 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PLIN3
Synonyms (NCBI Gene) Gene synonyms aliases
M6PRBP1, PP17, TIP47
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.3
Summary Summary of gene provided in NCBI Entrez Gene.
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs,
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016368 hsa-miR-193b-3p Proteomics 21512034
MIRT021117 hsa-miR-186-5p Sequencing 20371350
MIRT023413 hsa-miR-30b-5p Sequencing 20371350
MIRT025384 hsa-miR-34a-5p Proteomics 21566225
MIRT025384 hsa-miR-34a-5p Proteomics 21566225
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 19490898, 23593007, 25416956, 32296183, 32814053
GO:0005737 Component Cytoplasm TAS 9590177
GO:0005768 Component Endosome TAS 9590177
GO:0005794 Component Golgi apparatus TAS 9590177
GO:0005811 Component Lipid droplet IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
602702 16893 ENSG00000105355
Protein
UniProt ID O60664
Protein name Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17)
Protein function Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets (PubMed:34077757). Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03036 Perilipin 18 425 Perilipin family Family
Sequence
Sequence length 434
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Triglyceride catabolism
Retrograde transport at the Trans-Golgi-Network
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Lung carcinoma Carcinoma of lung rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355
View all (44 more)
28604730
Unknown
Disease term Disease name Evidence References Source
Vitiligo Vitiligo GWAS
Hypothyroidism Hypothyroidism GWAS
Carcinoma Carcinoma GWAS
Alzheimer disease Alzheimer disease GWAS
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 20081801, 37464334
Cystic Fibrosis Inhibit 33482299
Diabetes Mellitus Type 2 Associate 26171795
Hepatitis C Associate 26170028
Lung Neoplasms Stimulate 36293388
Non alcoholic Fatty Liver Disease Stimulate 37464334
Polycystic Ovary Syndrome Inhibit 25342854
Prostatic Neoplasms Associate 34410522