Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10198
Gene name Gene Name - the full gene name approved by the HGNC.	M-phase phosphoprotein 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MPHOSPH9
Synonyms (NCBI Gene) Gene synonyms aliases	MPP-9, MPP9
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q24.31

Show/Hide all(37)

miRTarBase ID	miRNA	Experiments	Reference
MIRT002676	hsa-miR-124-3p	Microarray	15685193
MIRT019557	hsa-miR-340-5p	Sequencing	20371350
MIRT020231	hsa-miR-130b-3p	Sequencing	20371350
MIRT002676	hsa-miR-124-3p	Microarray;Other	15685193
MIRT031174	hsa-miR-19b-3p	Sequencing	20371350
MIRT046416	hsa-miR-15b-5p	CLASH	23622248
MIRT1156120	hsa-miR-130a	CLIP-seq
MIRT1156121	hsa-miR-130b	CLIP-seq
MIRT1156122	hsa-miR-19a	CLIP-seq
MIRT1156123	hsa-miR-19b	CLIP-seq
MIRT1156124	hsa-miR-301a	CLIP-seq
MIRT1156125	hsa-miR-301b	CLIP-seq
MIRT1156126	hsa-miR-3163	CLIP-seq
MIRT1156127	hsa-miR-323-3p	CLIP-seq
MIRT1156128	hsa-miR-3666	CLIP-seq
MIRT1156129	hsa-miR-3944-5p	CLIP-seq
MIRT1156130	hsa-miR-4282	CLIP-seq
MIRT1156131	hsa-miR-4295	CLIP-seq
MIRT1156132	hsa-miR-4473	CLIP-seq
MIRT1156133	hsa-miR-4477a	CLIP-seq
MIRT1156134	hsa-miR-454	CLIP-seq
MIRT1156135	hsa-miR-4671-3p	CLIP-seq
MIRT1156136	hsa-miR-4789-5p	CLIP-seq
MIRT1156137	hsa-miR-671-5p	CLIP-seq
MIRT1156138	hsa-miR-944	CLIP-seq
MIRT2044656	hsa-miR-3152-5p	CLIP-seq
MIRT2044657	hsa-miR-340	CLIP-seq
MIRT2044658	hsa-miR-345	CLIP-seq
MIRT2044659	hsa-miR-4256	CLIP-seq
MIRT2044660	hsa-miR-4493	CLIP-seq
MIRT2044661	hsa-miR-4762-3p	CLIP-seq
MIRT2044662	hsa-miR-4774-3p	CLIP-seq
MIRT1156126	hsa-miR-3163	CLIP-seq
MIRT2044657	hsa-miR-340	CLIP-seq
MIRT2273902	hsa-miR-3668	CLIP-seq
MIRT2273903	hsa-miR-4773	CLIP-seq
MIRT2273904	hsa-miR-4796-5p	CLIP-seq

Show/Hide all(14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	20936779, 30375385, 36931259, 39251607
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IDA	8885239
GO:0005794	Component	Golgi apparatus	IEA
GO:0005813	Component	Centrosome	IDA	30375385
GO:0005813	Component	Centrosome	IEA
GO:0005814	Component	Centriole	IBA
GO:0005814	Component	Centriole	IDA	23644468, 30375385
GO:0005814	Component	Centriole	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:1902018	Process	Negative regulation of cilium assembly	IMP	30375385

MIM	HGNC	e!Ensembl
605501	7215	ENSG00000051825

Protein

UniProt ID

Q99550

Protein name

M-phase phosphoprotein 9

Protein function

Negatively regulates cilia formation by recruiting the CP110-CEP97 complex (a negative regulator of ciliogenesis) at the distal end of the mother centriole in ciliary cells (PubMed:30375385). At the beginning of cilia formation, MPHOSPH9 undergo

Family and domains

Sequence

MEEFDLVKTLHKTSSSVGSDENSLHSLGLNLNTDRSSPHLSTNGVSSFSGKTRPSVIQGT
VEVLTSLMQELQNSGKTDSELWKNCETRWLQLFNLVEKQCQEQIVAQQEQFHNQIQHIQE
EIKNLVKLQTSSASLASCEGNSSNKQVSSESQMGFFSLSSERNESVIHYPESTEPEIQQE
MSTSQPDCNVDSCSVSSGYGTFCISELNLYKSKDPKEFMEHIDVPKGQYVAPAVPAESLV
DGVKNENFYIQTPEECHVSLKEDVSISPGEFEHNFLGENKVSEVYSGKTNSNAITSWAQK
LKQNQPKRAHVEDGGSRSKQGNEQSKKTPIEKSDFAAATHPRAFYLSKPDETPNAWMSDS
GTGLTYWKLEEKDMHHSLPETLEKTFISLSSTDVSPNQSNTSNEMKLPSLKDIYYKKQRE
NKQLPERNLTSASNPNHPPEVLTLDPTLHMKPKQQISGIQPHGLPNALDDRISFSPDSVL
EPSMSSPSDIDSFSQASNVTSQLPGFPKYPSHTKASPVDSWKNQTFQNESRTSSTFPSVY
TITSNDISVNTVDEENTVMVASASVSQSQLPGTANSVPECISLTSLEDPVILSKIRQNLK
EKHARHIADLRAYYESEINSLKQKLEAKEISGVEDWKITNQILVDRCGQLDSALHEATSR
VRTLENKNNLLEIEVNDLRERFSAASSASKILQERIEEMRTSSKEKDNTIIRLKSRLQDL
EEAFENAYKLSDDKEAQLKQENKMFQDLLGEYESLGKEHRRVKDALNTTENKLLDAYTQI
SDLKRMISKLEAQVKQVEHENMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSI
FTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRETSDTPIMRALK
ELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLP
PSNRKSSTPTKREIMLTPVTVAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDT
VPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSSCPEPVPNGVKKVSVRTAWE
KNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGG
RITLQTRLNQEALEDRLERINRELGSVRMTLKKFHVLRTSANL

Sequence length

1183

Interactions

View interactions

Show/Hide Unknown Diseases (7)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Asthma	Asthma	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Insomnia	Insomnia	N/A	N/A	GWAS
Multiple Sclerosis	Multiple sclerosis	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS
Uterine Fibroids	Uterine fibroids	N/A	N/A	GWAS

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Diabetes Mellitus Type 2	Associate	25799151
Lymphoma Non Hodgkin	Associate	33951297
Multiple Sclerosis	Associate	20546594
Neoplasms	Stimulate	33174370
Neuroblastoma	Associate	20444257
Stomach Neoplasms	Stimulate	33174370
Tourette Syndrome	Associate	35354918
Venous Thromboembolism	Associate	31420334

MPHOSPH9 (M-phase phosphoprotein 9)