Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10184
Gene name Gene Name - the full gene name approved by the HGNC.
LHFPL tetraspan subfamily member 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LHFPL2
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q14.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-l
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019846 hsa-miR-375 Microarray 20215506
MIRT024177 hsa-miR-221-3p Sequencing 20371350
MIRT028068 hsa-miR-93-5p Sequencing 20371350
MIRT028386 hsa-miR-32-5p Sequencing 20371350
MIRT052375 hsa-let-7a-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0002576 Process Platelet degranulation TAS
GO:0003674 Function Molecular_function ND
GO:0005515 Function Protein binding IPI 32296183
GO:0005575 Component Cellular_component ND
GO:0005886 Component Plasma membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
609718 6588 ENSG00000145685
Protein
UniProt ID Q6ZUX7
Protein name LHFPL tetraspan subfamily member 2 protein (Lipoma HMGIC fusion partner-like 2 protein)
Protein function Plays a role in female and male fertility. Involved in distal reproductive tract development.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10242 L_HMGIC_fpl 9 204 Lipoma HMGIC fusion partner-like protein Family
Tissue specificity TISSUE SPECIFICITY: Expressed in all tissues and cell lines examined except brain and peripheral blood leukocytes. {ECO:0000269|PubMed:9039502}.
Sequence
Sequence length 228
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Platelet degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Glomerulonephritis IGA Glomerulonephritis rs778043831 25133636
Parkinson disease Parkinson Disease rs33939927, rs35801418, rs34805604, rs35870237, rs34995376, rs74315355, rs28940284, rs74315356, rs74315357, rs28940285, rs730880302, rs750664040, rs74315359, rs74315360, rs45539432
View all (84 more)
27402877
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 37589508
Coronary Disease Associate 28408707
Parkinson Disease Associate 27402877