CDH18 (cadherin 18)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1016
Gene name Gene Name - the full gene name approved by the HGNC.
Cadherin 18
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CDH18
Synonyms (NCBI Gene) Gene synonyms aliases
CDH14, CDH14L, CDH24
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5p14.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membra
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(6)
miRTarBase ID miRNA Experiments Reference
MIRT051690 hsa-let-7e-5p CLASH 23622248
MIRT2197344 hsa-miR-198 CLIP-seq
MIRT2197345 hsa-miR-3691-3p CLIP-seq
MIRT2197346 hsa-miR-4267 CLIP-seq
MIRT2197347 hsa-miR-4277 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(14)
GO ID Ontology Definition Evidence Reference
GO:0000902 Process Cell morphogenesis IBA 21873635
GO:0005509 Function Calcium ion binding IBA 21873635
GO:0005886 Component Plasma membrane TAS
GO:0005912 Component Adherens junction IBA 21873635
GO:0007043 Process Cell-cell junction assembly IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
603019 1757 ENSG00000145526
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q13634
Protein name Cadherin-18 (Cadherin-14)
Protein function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00028 Cadherin 58 → 150 Cadherin domain Domain
PF00028 Cadherin 164 → 259 Cadherin domain Domain
PF00028 Cadherin 273 → 374 Cadherin domain Domain
PF00028 Cadherin 388 → 479 Cadherin domain Domain
PF00028 Cadherin 492 → 589 Cadherin domain Domain
PF01049 Cadherin_C 637 → 784 Cadherin cytoplasmic region Family
Sequence
Sequence length 790
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Adherens junctions interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Hypertension Hypertensive disease rs13306026 28498854
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Leprosy Leprosy 25642632 ClinVar, GWAS
Dementia Dementia GWAS
Show/Hide Text Mining Associations (13)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 35242247
Apraxias Associate 27120335
Carcinogenesis Associate 37025097
Endometrial Hyperplasia Associate 37780629
Endometrial Neoplasms Associate 37780629
Heart Defects Congenital Associate 30342662
Lymphoma Associate 34166375
Metabolic Syndrome Associate 23628382, 30852652
Migraine Disorders Associate 34380431
Moyamoya Disease Associate 39238003