AKAP9 (A-kinase anchoring protein 9)

Gene

• Entrez ID: 10142
• Gene name: A-kinase anchoring protein 9
• Gene symbol: AKAP9
• Synonyms (NCBI Gene): AKAP-9, AKAP350, AKAP450, CG-NAP, HYPERION, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO
• Chromosome: 7
• Chromosome location: 7q21.2
• Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene e

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs56198613	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Synonymous variant, coding sequence variant
rs61757663	G>C	Conflicting-interpretations-of-pathogenicity, likely-benign	Missense variant, coding sequence variant
rs61757664	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity, likely-benign	Missense variant, coding sequence variant
rs61757671	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity, likely-benign	Missense variant, coding sequence variant
rs77447750	T>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity, likely-benign	3 prime UTR variant, missense variant, coding sequence variant
rs121908566	C>T	Uncertain-significance, pathogenic	Missense variant, coding sequence variant, genic upstream transcript variant
rs139965373	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, coding sequence variant, missense variant
rs144875383	A>C	Conflicting-interpretations-of-pathogenicity, likely-benign	Coding sequence variant, missense variant
rs144888041	G>C	Benign, likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, coding sequence variant, missense variant
rs189083857	C>G	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, genic upstream transcript variant
rs192046591	A>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, upstream transcript variant, intron variant
rs201958512	A>G	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant
rs201977551	T>C,G	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Synonymous variant, missense variant, coding sequence variant
rs367857951	T>C	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Missense variant, coding sequence variant, genic upstream transcript variant
rs376950905	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Missense variant, coding sequence variant
rs553800160	A>C	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant
rs730880043	G>T	Likely-pathogenic	Coding sequence variant, genic upstream transcript variant, stop gained
rs796052199	T>A	Likely-pathogenic	Coding sequence variant, missense variant, genic upstream transcript variant
rs796052200	T>A	Likely-pathogenic	Coding sequence variant, missense variant, genic upstream transcript variant
rs1563145763	G>A	Likely-pathogenic	Coding sequence variant, stop gained

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004170	hsa-miR-192-5p	Microarray	16822819
MIRT030952	hsa-miR-21-5p	Microarray	19242418
MIRT776003	hsa-miR-1206	CLIP-seq
MIRT776004	hsa-miR-1226	CLIP-seq
MIRT776005	hsa-miR-1279	CLIP-seq
MIRT776006	hsa-miR-1283	CLIP-seq
MIRT776007	hsa-miR-133a	CLIP-seq
MIRT776008	hsa-miR-133b	CLIP-seq
MIRT776009	hsa-miR-300	CLIP-seq
MIRT776010	hsa-miR-3120-5p	CLIP-seq
MIRT776011	hsa-miR-3145-3p	CLIP-seq
MIRT776012	hsa-miR-3149	CLIP-seq
MIRT776013	hsa-miR-320e	CLIP-seq
MIRT776014	hsa-miR-3689a-5p	CLIP-seq
MIRT776015	hsa-miR-3689b	CLIP-seq
MIRT776016	hsa-miR-3689e	CLIP-seq
MIRT776017	hsa-miR-3689f	CLIP-seq
MIRT776018	hsa-miR-381	CLIP-seq
MIRT776019	hsa-miR-4281	CLIP-seq
MIRT776020	hsa-miR-4423-3p	CLIP-seq
MIRT776021	hsa-miR-4666-3p	CLIP-seq
MIRT776022	hsa-miR-4684-5p	CLIP-seq
MIRT776023	hsa-miR-4733-3p	CLIP-seq
MIRT776024	hsa-miR-513b	CLIP-seq
MIRT776025	hsa-miR-568	CLIP-seq
MIRT776026	hsa-miR-656	CLIP-seq
MIRT776027	hsa-miR-936	CLIP-seq
MIRT776028	hsa-miR-3133	CLIP-seq
MIRT776024	hsa-miR-513b	CLIP-seq
MIRT776029	hsa-miR-520d-5p	CLIP-seq
MIRT776030	hsa-miR-524-5p	CLIP-seq
MIRT776031	hsa-miR-548b-3p	CLIP-seq
MIRT1929006	hsa-miR-106a	CLIP-seq
MIRT1929007	hsa-miR-106b	CLIP-seq
MIRT1929008	hsa-miR-1197	CLIP-seq
MIRT1929009	hsa-miR-1286	CLIP-seq
MIRT1929010	hsa-miR-145	CLIP-seq
MIRT1929011	hsa-miR-17	CLIP-seq
MIRT1929012	hsa-miR-181a	CLIP-seq
MIRT1929013	hsa-miR-181b	CLIP-seq
MIRT1929014	hsa-miR-181c	CLIP-seq
MIRT1929015	hsa-miR-181d	CLIP-seq
MIRT1929016	hsa-miR-2054	CLIP-seq
MIRT1929017	hsa-miR-20a	CLIP-seq
MIRT1929018	hsa-miR-20b	CLIP-seq
MIRT1929019	hsa-miR-214	CLIP-seq
MIRT1929020	hsa-miR-34b	CLIP-seq
MIRT1929021	hsa-miR-3619-5p	CLIP-seq
MIRT1929022	hsa-miR-4262	CLIP-seq
MIRT1929023	hsa-miR-4275	CLIP-seq
MIRT1929024	hsa-miR-4291	CLIP-seq
MIRT1929025	hsa-miR-4436a	CLIP-seq
MIRT1929026	hsa-miR-4643	CLIP-seq
MIRT1929027	hsa-miR-466	CLIP-seq
MIRT776021	hsa-miR-4666-3p	CLIP-seq
MIRT1929028	hsa-miR-4668-3p	CLIP-seq
MIRT1929029	hsa-miR-4722-5p	CLIP-seq
MIRT1929030	hsa-miR-4789-3p	CLIP-seq
MIRT1929031	hsa-miR-519a	CLIP-seq
MIRT1929032	hsa-miR-519b-3p	CLIP-seq
MIRT1929033	hsa-miR-519c-3p	CLIP-seq
MIRT1929034	hsa-miR-519d	CLIP-seq
MIRT1929035	hsa-miR-548n	CLIP-seq
MIRT1929036	hsa-miR-548t	CLIP-seq
MIRT1929037	hsa-miR-561	CLIP-seq
MIRT1929038	hsa-miR-761	CLIP-seq
MIRT1929039	hsa-miR-922	CLIP-seq
MIRT1929040	hsa-miR-93	CLIP-seq
MIRT776021	hsa-miR-4666-3p	CLIP-seq
MIRT2169696	hsa-miR-1179	CLIP-seq
MIRT776014	hsa-miR-3689a-5p	CLIP-seq
MIRT776015	hsa-miR-3689b	CLIP-seq
MIRT776016	hsa-miR-3689e	CLIP-seq
MIRT776017	hsa-miR-3689f	CLIP-seq
MIRT2169697	hsa-miR-3692	CLIP-seq
MIRT2169698	hsa-miR-409-3p	CLIP-seq
MIRT2169699	hsa-miR-4307	CLIP-seq
MIRT2169700	hsa-miR-4719	CLIP-seq
MIRT1929012	hsa-miR-181a	CLIP-seq
MIRT1929013	hsa-miR-181b	CLIP-seq
MIRT1929014	hsa-miR-181c	CLIP-seq
MIRT1929015	hsa-miR-181d	CLIP-seq
MIRT1929016	hsa-miR-2054	CLIP-seq
MIRT1929019	hsa-miR-214	CLIP-seq
MIRT2472433	hsa-miR-3161	CLIP-seq
MIRT1929021	hsa-miR-3619-5p	CLIP-seq
MIRT2472434	hsa-miR-374a	CLIP-seq
MIRT2472435	hsa-miR-374b	CLIP-seq
MIRT1929022	hsa-miR-4262	CLIP-seq
MIRT1929024	hsa-miR-4291	CLIP-seq
MIRT2472436	hsa-miR-4457	CLIP-seq
MIRT1929026	hsa-miR-4643	CLIP-seq
MIRT1929027	hsa-miR-466	CLIP-seq
MIRT2472437	hsa-miR-4731-3p	CLIP-seq
MIRT1929030	hsa-miR-4789-3p	CLIP-seq
MIRT2472438	hsa-miR-4801	CLIP-seq
MIRT2472439	hsa-miR-5096	CLIP-seq
MIRT1929035	hsa-miR-548n	CLIP-seq
MIRT1929036	hsa-miR-548t	CLIP-seq
MIRT1929037	hsa-miR-561	CLIP-seq
MIRT2472440	hsa-miR-624	CLIP-seq
MIRT2472441	hsa-miR-660	CLIP-seq
MIRT1929038	hsa-miR-761	CLIP-seq
MIRT1929039	hsa-miR-922	CLIP-seq
MIRT1929012	hsa-miR-181a	CLIP-seq
MIRT1929013	hsa-miR-181b	CLIP-seq
MIRT1929014	hsa-miR-181c	CLIP-seq
MIRT1929015	hsa-miR-181d	CLIP-seq
MIRT1929016	hsa-miR-2054	CLIP-seq
MIRT1929019	hsa-miR-214	CLIP-seq
MIRT1929021	hsa-miR-3619-5p	CLIP-seq
MIRT1929022	hsa-miR-4262	CLIP-seq
MIRT1929024	hsa-miR-4291	CLIP-seq
MIRT1929026	hsa-miR-4643	CLIP-seq
MIRT1929027	hsa-miR-466	CLIP-seq
MIRT1929030	hsa-miR-4789-3p	CLIP-seq
MIRT2472439	hsa-miR-5096	CLIP-seq
MIRT1929035	hsa-miR-548n	CLIP-seq
MIRT1929036	hsa-miR-548t	CLIP-seq
MIRT1929037	hsa-miR-561	CLIP-seq
MIRT1929038	hsa-miR-761	CLIP-seq
MIRT1929039	hsa-miR-922	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005102	Function	Signaling receptor binding	TAS	9482789
GO:0005515	Function	Protein binding	IPI	12163479, 16980960, 18772391, 19242490, 20466722, 23455924, 25416956, 27666745, 28089391, 28514442, 29162697, 29961565, 31413325, 32353859, 32814053, 33060197, 33961781, 36217030
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IDA	12163479, 27666745
GO:0005794	Component	Golgi apparatus	IEA
GO:0005795	Component	Golgi stack	IBA
GO:0005795	Component	Golgi stack	IDA	19242490
GO:0005801	Component	Cis-Golgi network	IBA
GO:0005801	Component	Cis-Golgi network	IDA	24648492
GO:0005813	Component	Centrosome	IBA
GO:0005813	Component	Centrosome	IDA	20096683, 21399614, 24648492, 25657325, 29162697
GO:0005813	Component	Centrosome	IEA
GO:0005813	Component	Centrosome	TAS	10202149
GO:0005815	Component	Microtubule organizing center	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005856	Component	Cytoskeleton	TAS	9482789
GO:0007020	Process	Microtubule nucleation	IBA
GO:0007020	Process	Microtubule nucleation	IMP	19242490
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	10390370
GO:0007268	Process	Chemical synaptic transmission	TAS	9482789
GO:0008076	Component	Voltage-gated potassium channel complex	IDA	11799244
GO:0015459	Function	Potassium channel regulator activity	IBA
GO:0015459	Function	Potassium channel regulator activity	IMP	16002409
GO:0031116	Process	Positive regulation of microtubule polymerization	IMP	29162697
GO:0031503	Process	Protein-containing complex localization	IDA	19218243
GO:0034237	Function	Protein kinase A regulatory subunit binding	IBA
GO:0034237	Function	Protein kinase A regulatory subunit binding	IDA	21502359
GO:0034237	Function	Protein kinase A regulatory subunit binding	IEA
GO:0034237	Function	Protein kinase A regulatory subunit binding	IPI	17911601
GO:0034705	Component	Potassium channel complex	IDA	19218243
GO:0043025	Component	Neuronal cell body	IEA
GO:0044307	Component	Dendritic branch	IEA
GO:0044325	Function	Transmembrane transporter binding	IPI	11799244, 16002409, 18093912
GO:0051602	Process	Response to electrical stimulus	IEA
GO:0051661	Process	Maintenance of centrosome location	IBA
GO:0051661	Process	Maintenance of centrosome location	IMP	25657325
GO:0060090	Function	Molecular adaptor activity	IBA
GO:0060090	Function	Molecular adaptor activity	IDA	11799244, 27666745
GO:0060090	Function	Molecular adaptor activity	IEA
GO:0060306	Process	Regulation of membrane repolarization	IMP	16002409
GO:0060307	Process	Regulation of ventricular cardiac muscle cell membrane repolarization	IMP	18093912
GO:0071320	Process	Cellular response to cAMP	IMP	16002409, 18093912
GO:0086091	Process	Regulation of heart rate by cardiac conduction	IMP	18093912
GO:0097060	Component	Synaptic membrane	IBA
GO:0097060	Component	Synaptic membrane	IEA
GO:0098909	Process	Regulation of cardiac muscle cell action potential involved in regulation of contraction	IMP	18093912
GO:0098978	Component	Glutamatergic synapse	IDA	10390370
GO:0098978	Component	Glutamatergic synapse	IMP	10390370
GO:0099104	Function	Potassium channel activator activity	IMP	18093912
GO:0099147	Component	Extrinsic component of postsynaptic density membrane	IEA
GO:1903358	Process	Regulation of Golgi organization	IDA	27666745

Other IDs

• MIM: 604001
• HGNC: 379
• e!Ensembl: ENSG00000127914

Protein

• UniProt ID: Q99996
• Protein name: A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein
• Protein function: Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus (PubMed:10202149, PubMed:15047863). Required for microtubule nucleation
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10495	PACT_coil_coil	3704 → 3785	Pericentrin-AKAP-450 domain of centrosomal targeting protein	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed (PubMed:10202149). Isoform 4: Highly expressed in skeletal muscle and in pancreas (PubMed:9482789). {ECO:0000269|PubMed:10202149, ECO:0000269|PubMed:9482789}.
• Sequence:

  MEDEERQKKLEAGKAKLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHDVSAHHDLNIDQS
  QCNEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEISTTADDCSSEVNG
  CSFVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMMESELAGKQHEIEELNRELEE
  MRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQI
  QFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISF
  LQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLG
  ELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQ
  RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSN
  ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS
  REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL
  EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG
  IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ
  INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL
  KDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLN
  EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL
  HLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLS
  DLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLL
  DGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTK
  ESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKD
  KALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECS
  YFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTLL
  NKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVN
  HKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSESTV
  PPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNIVKLLEKQYQEQL
  EEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQIGF
  QTFETVDVKFKEEFKPLSKELGEHGKEILLSNSDPHDIPESKDCVLTISEEMFSKDKTFI
  VRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQR
  EDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRN
  SSTQTQNGNENQGEVEEQTFKEKELDRKPEDVPPEILSNERYALQKANNRLLKILLEVVK
  TTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSG
  SDMPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEA
  ISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKA
  EGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQK
  EAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIEL
  EQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRF
  QPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQAL
  LVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELE
  NKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLF
  GKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQEC
  VKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQ
  QVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSK
  DKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYK
  QIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSE
  PERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKE
  KKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVA
  TKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE
  SKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEI
  ISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEECGTLKAVIQCLRS
  KEGSSIPELAHSDAYQTREICSSDSGSDWGQGIYLTHSQGFDIASEGRGEESESATDSFP
  KKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKDLITK
  MQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTDAVGL
  LNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQE
  LLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLK
  AQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKE
  ELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV
  LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIV
  ELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLE
  EKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNW
  VLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFE
  TADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELTGHIS
  QLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWNREKL
  TLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALIYQKK
  YLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAISRMKF
  LVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSDLDYI
  RSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSGSTTQ
  FHAGMRR

• Sequence length: 3907

Pathways

Reactome:

Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Phase 3 - rapid repolarisation
Phase 2 - plateau phase
Anchoring of the basal body to the plasma membrane
Signaling by BRAF and RAF fusions
AURKA Activation by TPX2

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Long QT syndrome	Likely pathogenic	rs796052199, rs796052200	RCV000190222 RCV000190223
Long QT syndrome 11	Likely pathogenic	rs730880043	RCV000157100

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
AKAP9-related disorder	Likely benign; Benign; Uncertain significance; Conflicting classifications of pathogenicity	rs745898364, rs775989174, rs371133254, rs150968594, rs144662445, rs61757665, rs1214206783, rs765475242, rs749167841, rs771712081, rs139965373, rs151021935, rs34953651, rs144615758, rs141990258, rs149244653, rs367857951, rs139612565, rs34086871, rs61757671, rs786205262, rs144875383, rs201958512, rs61757664, rs144054367, rs139770404, rs147494754, rs767167128, rs141039834, rs751625334, rs756398963, rs2535278710, rs1248370802, rs772513653, rs151197146, rs180926926, rs751615449, rs138928104, rs1195627112, rs1157261703, rs2535335924, rs765469584, rs138390702, rs139963188, rs568626378, rs115624293, rs149341527, rs779280501, rs149979685, rs374340343, rs749254312, rs754974720, rs184184931, rs61757675, rs750905383, rs546600149, rs779260877, rs748951815, rs143473598, rs142092767, rs762012353, rs369522150, rs893173151, rs1425297084	RCV003953750 RCV003953759 RCV003948446 RCV003905186 RCV003952635 RCV003905187 RCV003407862 RCV004746521 RCV003416533 RCV003978656 RCV003975223 RCV003975224 RCV003907534 RCV003947450 RCV003917582 RCV003965223 RCV003907540 RCV003907541 RCV003927572 RCV003982921 RCV003422064 RCV003907542 RCV003927571 RCV003937537 RCV003917587 RCV003937748 RCV003927876 RCV003977668 RCV003907875 RCV003909891 RCV003955398 RCV003400451 RCV003410617 RCV003929282 RCV003922603 RCV003957850 RCV004745360 RCV003972520 RCV004747407 RCV003982808 RCV003941396 RCV003937272 RCV003902716 RCV003942576 RCV003932770 RCV003942575 RCV003902715 RCV003900120 RCV003942739 RCV003979946 RCV003928033 RCV003905663 RCV003980199 RCV003953097 RCV003420092 RCV003411779 RCV003411786 RCV003892774 RCV003938226 RCV003892780 RCV003975436 RCV003414000 RCV003393897 RCV003945937
Amyloidosis	Benign; Likely benign	rs141856443	RCV000853027
Arrhythmogenic right ventricular cardiomyopathy	Conflicting classifications of pathogenicity	rs144054367	RCV000853025
Atrial fibrillation	Benign; Likely benign	rs35669569	RCV000853010
Brugada syndrome	Conflicting classifications of pathogenicity	rs539375675	RCV005357923
Brugada syndrome 1	Conflicting classifications of pathogenicity	rs144888041	RCV000584786
Cardiac arrest	Likely benign; Uncertain significance	rs138161478, rs730880044, rs533277424, rs869025356	RCV000157098 RCV000157105 RCV000208026 RCV000208457
Cardiac arrhythmia	Benign; Likely benign; Conflicting classifications of pathogenicity	rs71292989, rs786205709, rs193922723	RCV001842507 RCV001842508 RCV001841513
Cardiomyopathy	Uncertain significance; Benign; Likely benign; Conflicting classifications of pathogenicity	rs777030400, rs35669569, rs34086871, rs76177450, rs61757673, rs201048693, rs376950905, rs141990258, rs1229169680, rs1042630361	RCV006255216 RCV000853010 RCV000853014 RCV000853018 RCV000853023 RCV000853024 RCV000853016 RCV000853015 RCV000853017 RCV000853019
Cardiovascular phenotype	Uncertain significance; Conflicting classifications of pathogenicity; Likely benign; Benign	rs61757668, rs147247719, rs140973676, rs1800906846, rs1423656714, rs762794527, rs1443301693, rs541209445, rs756966573, rs376670169, rs142509451, rs373613868, rs886038911, rs754569380, rs148318643, rs571076507, rs1799153881, rs756171219, rs1424485718, rs148726562, rs1207821150, rs767058162, rs776217591, rs537613965, rs759179468, rs756203652, rs548234238, rs910995516, rs751606673, rs1562947323, rs2130664563, rs2130667121, rs746651292, rs1193122767, rs1376477395, rs925619682, rs772512812, rs765553799, rs773105182, rs779652992, rs1814426128, rs761435123, rs761824694, rs1052036778, rs764711357, rs1818679501, rs185898118, rs374138966, rs781051056, rs1810606397, rs766673963, rs745898364, rs1199129544, rs775989174, rs998815963, rs2130646545, rs1228322452, rs770476104, rs1490213211, rs765888359, rs368222299, rs780211536, rs375897283, rs759583976, rs370129982, rs150138799, rs749770109, rs564064961, rs375586792, rs1801493738, rs780559414, rs141237587, rs757137701, rs760761631, rs1172853201, rs769718964, rs150736347, rs1471564069, rs372167195, rs777713030, rs371133254, rs547028589, rs141830654, rs752723636, rs1584452484, rs763275688, rs139192857, rs761734539, rs755516007, rs2130924831, rs768859701, rs1802542345, rs747304560, rs188264356, rs1430748591, rs767966419, rs1346719880, rs892241767, rs955404695, rs1359148155, rs137971303, rs1278796067, rs146648044, rs372568340, rs770850802, rs200034525, rs776312514, rs374724127, rs147876926, rs763770694, rs762460761, rs750350575, rs200596189, rs372941888, rs372076987, rs758623712, rs372425259, rs1440127984, rs749538379, rs1376652098, rs2130860716, rs146186205, rs768686908, rs769119204, rs769098388, rs1016368660, rs1562978382, rs767035977, rs1277410775, rs1176473354, rs779393285, rs368183690, rs868546210, rs761921630, rs182048899, rs1240091785, rs372844164, rs149357648, rs981017281, rs2130891688, rs1445749676, rs566937987, rs774408420, rs2230768, rs150016098, rs10236397, rs587780849, rs150968594, rs61757672, rs35759833, rs144662445, rs6960867, rs756486044, rs10228334, rs1063242, rs28927678, rs1063243, rs142401936, rs6964587, rs61757665, rs1989779, rs13245393, rs1408184706, rs373730126, rs1214206783, rs762609050, rs765475242, rs765144371, rs199780481, rs1240295587, rs199577930, rs1290288696, rs142831346, rs1351358009, rs572101398, rs369263681, rs748884520, rs369047678, rs2130860788, rs755049262, rs761783446, rs538801309, rs1040204302, rs553209225, rs374309022, rs144615758, rs1397831091, rs371664197, rs1475038289, rs751675949, rs756215009, rs1183671911, rs779122050, rs978219635, rs200327385, rs1563101732, rs948846648, rs759694779, rs905116504, rs148442799, rs747346120, rs369212896, rs906395966, rs140457022, rs761946454, rs1157417207, rs565850417, rs1363239151, rs139337441, rs1801192661, rs367997608, rs1280293616, rs372297197, rs779901993, rs746505983, rs776190475, rs1800893766, rs1471739869, rs2130900919, rs376638814, rs2130862031, rs61746591, rs754949903, rs1318456659, rs763681864, rs147986403, rs768107825, rs539934550, rs140053176, rs547958010, rs749167841, rs146264747, rs1469597087, rs550448097, rs1809744474, rs1305633544, rs768097461, rs774938501, rs778297562, rs201128911, rs574683571, rs1802527615, rs772173332, rs145915675, rs746472680, rs556260953, rs780419888, rs1384886142, rs771712081, rs537731606, rs770983849, rs746485312, rs753770347, rs907372253, rs886039192, rs1437373369, rs764654898, rs144893755, rs765317913, rs541883996, rs143259647, rs1344474912, rs1409141394, rs755614570, rs771287562, rs779524120, rs751636798, rs754882162, rs2130875407, rs2130646435, rs1259922164, rs571425127, rs766184161, rs762754861, rs2535318541, rs1240832304, rs2484622586, rs1238314038, rs370276249, rs774732981, rs1241305439, rs774196711, rs1562963640, rs2484697013, rs775317970, rs138161478, rs139965373, rs730880045, rs151021935, rs138468216, rs543634397, rs730880044, rs1295589910, rs767126052, rs1801193542, rs1388009164, rs369061534, rs1460660381, rs188318223, rs778100661, rs757383243, rs778955236, rs369862231, rs1336655717, rs1267824964, rs988349389, rs750252641, rs1390402540, rs754843357, rs755066824, rs2484720888, rs760966956, rs2484731190, rs755857275, rs2535331920, rs1292145089, rs761236914, rs779776032, rs762115704, rs758456170, rs1449568966, rs2535335691, rs2535335836, rs1203769632, rs767584253, rs1288116605, rs764231357, rs1361230486, rs2484807646, rs1196612780, rs1428052119, rs758115766, rs1360525453, rs2484697247, rs1012576562, rs2484721412, rs372572545, rs1212624660, rs1390307317, rs899043502, rs756679946, rs1286032853, rs887720617, rs1801485947, rs2484734147, rs868109719, rs574347880, rs750656682, rs1816733498, rs757753258, rs376870775, rs771486558, rs759159224, rs140271624, rs1008912458, rs1391898100, rs1170845496, rs2484622663, rs751533517, rs2484697145, rs369441906, rs2535300540, rs1443045387, rs755453815, rs369882717, rs2484663081, rs149641207, rs370061409, rs776533579, rs1167743012, rs375993686, rs774587200, rs781303159, rs2484807733, rs1373360499, rs1488696055, rs775361518, rs2484808730, rs1554426964, rs756752696, rs1032687352, rs1805577610, rs756990151, rs1465148408, rs756131845, rs749383289, rs745498011, rs1401330274, rs2484823109, rs1806730582, rs1229060941, rs1286918956, rs1420205598, rs1808210864, rs1808211243, rs1808213425, rs756880227, rs376631476, rs1027014437, rs772261291, rs765704985, rs780100627, rs778790678, rs745606140, rs1055578457, rs1308108893, rs186058479, rs2535208324, rs774755869, rs937791197, rs1487757753, rs772229774, rs375182237, rs2484808585, rs2484808605, rs536841769, rs1806317286, rs758207667, rs1217820914, rs774153068, rs2535190771, rs770002854, rs2535190854, rs182445675, rs772181773, rs766060779, rs1353892514, rs1262156619, rs2535195530, rs2535300823, rs945598717, rs2535208050, rs1205013152, rs773455040, rs2535221465, rs760453118, rs987632006, rs1196844754, rs1348186476, rs1383050508, rs1805967760, rs1470232952, rs774737080, rs928235051, rs368004938, rs752578751, rs2535195027, rs749616629, rs1810033476, rs2535204019, rs1039863676, rs2484671272, rs2535218708, rs2535218818, rs770443947, rs1051721340, rs769896624, rs774332915, rs886062467, rs754034590, rs759007219, rs1295735076, rs755498039, rs1198747710, rs1806209054, rs533352983, rs766763485, rs2535194615, rs930294584, rs149204469, rs2535194794, rs1810017623, rs2535218297, rs939208704, rs772504394, rs1811443186, rs752485780, rs1187168017, rs2535221741, rs2535221758, rs2535236353, rs2535236358, rs2484671408, rs1487087847, rs755797374, rs1196784193, rs1446704941, rs1331022410, rs2535245052, rs150229698, rs1469427280, rs141470927, rs1816700242, rs1276558790, rs1220477751, rs1488811536, rs752626437, rs750551851, rs747994062, rs753633654, rs988448987, rs2535258208, rs2535258322, rs764675849, rs1813938778, rs1447017311, rs1814239687, rs1180881855, rs1181749353, rs2535277776, rs2535277956, rs1815155123, rs371536340, rs752762680, rs1263767103, rs772296471, rs1347909469, rs1813126987, rs1166104018, rs748300250, rs1205692229, rs776261566, rs2484676076, rs1813191901, rs2484676113, rs752006269, rs775429275, rs745346171, rs2535247319, rs371753464, rs2535300986, rs368001901, rs2535257833, rs1813910200, rs963879028, rs370771679, rs908030381, rs2535269397, rs546876949, rs2535269719, rs772120685, rs1037309802, rs746988070, rs1816330429, rs144538179, rs759683044, rs1468640383, rs1813112972, rs749716365, rs560187315, rs1813175806, rs1813180723, rs2484598434, rs984927444, rs766108106, rs754507617, rs770325011, rs1813966442, rs2535259214, rs1813984684, rs148603859, rs2535267007, rs745808888, rs2535269169, rs1264961491, rs530613238, rs139479927, rs2535289051, rs2484688467, rs2484688473, rs749921738, rs762611117, rs1403214059, rs1795351636, rs772366481, rs766629770, rs200250245, rs1435679080, rs375743146, rs762175660, rs1207633245, rs1813776857, rs2535255287, rs2535258564, rs1236740692, rs2535266490, rs1375511184, rs2535266540, rs1312515973, rs1416774999, rs776938362, rs996476158, rs749833223, rs1196424928, rs757953782, rs761741274, rs951764561, rs1816641928, rs753546371, rs2535299154, rs1449431323, rs2535299340, rs2535299935, rs1352400309, rs2535300047, rs140462821, rs1305130423, rs559508511, rs1799190664, rs1426083577, rs1412898900, rs1334061465, rs774842633, rs1298777045, rs761646754, rs1014803047, rs1473679847, rs904851489, rs2535299851, rs867646139, rs1799077439, rs1816776801, rs1183330019, rs1816849732, rs2535302747, rs2535302916, rs1163076461, rs1799200073, rs2535303187, rs1816923793, rs1433272242, rs780179627, rs747117357, rs376703608, rs781744583, rs1170309661, rs2484689859, rs2484690091, rs749473172, rs2535302633, rs926370853, rs371522837, rs772510251, rs771923922, rs1584037958, rs1009919389, rs1440681292, rs1584542692, rs2535304560, rs2535304573, rs1423223603, rs2484477626, rs1584039463, rs770556341, rs771608420, rs1799137106, rs944150920, rs2484598729, rs1290104896, rs2484690011, rs1584033976, rs375521344, rs145033147, rs200030267, rs1799212375, rs769670110, rs762780139, rs2484688812, rs1453382766, rs1799224441, rs376021695, rs2535308509, rs1332040015, rs2484692586, rs141176252, rs971851892, rs1394849857, rs2535312112, rs774880478, rs1165990371, rs772376735, rs777030400, rs1799303998, rs2484694388, rs374100390, rs1816932363, rs758729015, rs2535308610, rs763751035, rs2484688878, rs1795366129, rs777621177, rs2484599089, rs2484693364, rs745858523, rs1375321033, rs780160560, rs375189777, rs777495665, rs2484688980, rs1347088192, rs750871444, rs1799299897, rs2484692033, rs2484692074, rs774286914, rs377735460, rs762574367, rs1354500244, rs2484693623, rs2130909664, rs1584542922, rs752551147, rs1054556530, rs773017487, rs750984360, rs2535308577, rs765951390, rs183942717, rs1799245251, rs2484599060, rs2484693102, rs761249322, rs765133006, rs2484693207, rs1176581695, rs769625141, rs1799305924, rs1060504955, rs2484695102, rs367762142, rs2484695147, rs748461520, rs2484694857, rs766339646, rs2484599409, rs1158379374, rs2484695597, rs34101758, rs1817777006, rs754493921, rs2484694708, rs1271209944, rs1234676587, rs1317491861, rs745614058, rs1245398203, rs2535318526, rs2484599443, rs755549001, rs781743438, rs763312542, rs770244495, rs1490879515, rs2484695320, rs1799346462, rs559598625, rs1254555386, rs756597777, rs2484695773, rs1455168198, rs149825027, rs1295931115, rs933536639, rs764164178, rs780459368, rs368807621, rs2535288562, rs1799069782, rs752156538, rs755408339, rs768026366, rs34953651, rs786205712, rs144888041, rs148920964, rs142673316, rs786205713, rs534185372, rs10644111, rs144372406, rs777627168, rs786205707, rs141990258, rs149244653, rs139468199, rs786205709, rs773428761, rs140470576, rs61757663, rs139046510, rs145675748, rs778568641, rs200821358, rs1019010778, rs747112882, rs1584334350, rs35669569, rs200518712, rs367857951, rs60031334, rs143894795, rs202091548, rs61757557, rs146797353, rs762293635, rs139612565, rs73407505, rs150379637, rs34086871, rs201632145, rs189083857, rs776979647, rs61757671, rs73226383, rs76177450, rs201977551, rs553800160, rs786205262, rs144875383, rs201958512, rs61757673, rs199762211, rs201048693, rs144021475, rs78351282, rs146495719, rs34956633, rs61757664, rs750007670, rs144054367, rs142729919, rs186148498, rs143306820, rs141856443, rs199527737, rs77447750, rs1799097592, rs1806214846, rs1813970987, rs755110736, rs751090118, rs1391373531, rs767106255, rs777988488, rs56198613, rs1036949055, rs372132898, rs1394216775, rs746546794, rs2484689505, rs766201022, rs1212640163, rs2484815643, rs1008740513, rs2484693597, rs1799235296, rs2484666480, rs776193956, rs752167348, rs2484692051, rs1298751672, rs1222761099, rs121908566, rs747777578, rs1799216709, rs764285952, rs756687571, rs373876340, rs776345336, rs139770404, rs143627839, rs528888059, rs2484671444, rs773523925, rs1376889041, rs993488428, rs754974720, rs1817784228, rs2484691193, rs1253696193, rs1186808279, rs938604667, rs1278236570, rs78515732, rs151038875, rs143712699, rs147494754, rs748742676, rs533277424, rs143283097, rs753467156, rs763942446, rs763549392, rs781409804, rs144170939, rs2535294764, rs2535246381, rs771040833, rs779137184, rs1801492188, rs2484693639, rs1260195887, rs2535247430, rs750345591, rs751812398, rs80191629, rs767167128, rs749315335, rs148267537, rs147158224, rs141039834, rs146305558, rs150332727, rs746961943, rs749082483, rs775991910, rs878854812, rs146710448, rs535686431, rs767337890, rs2535244614, rs772182187, rs1817210905, rs969130822, rs2484781081, rs1584285416, rs764321112, rs1799070800, rs1034432737, rs2535288532, rs1290596598, rs1813134631, rs1276941048, rs2535269673, rs2484808439, rs1799318590, rs1283297655, rs1329984046, rs767454911, rs2484816154, rs1356418352, rs2130873627, rs2535247779, rs1818905644, rs1293817927, rs1177146640, rs769042540, rs1813941617, rs2484695372, rs1271398612, rs1165716443, rs1811455362, rs1418934614, rs781213530, rs1439237476, rs1813907280, rs748951815, rs776845991, rs1156383005, rs2535259285, rs1052013069, rs2535288602, rs2535191045, rs2484666085, rs1584601292, rs1584040089, rs2484676328, rs780775109, rs1223177321, rs1298504605, rs2535244901, rs2535244911, rs1813208943, rs2535318428, rs1805968176, rs2535302847, rs1799361733, rs557411136, rs74746725, rs2535208102, rs2535263663, rs2535218541, rs751383195, rs2484807933, rs748910873, rs546024452, rs756863406, rs199744254, rs1814542252, rs1172115467, rs1216908478, rs759956336, rs747894504, rs200976922, rs140664656, rs767404316, rs200078353, rs34370932, rs756987521, rs763924466, rs886039202, rs760328706, rs376262014, rs886039037, rs145763255, rs752178666, rs886039006, rs886038914, rs147194783, rs141156177, rs886038843, rs373320584, rs754011064, rs886038923, rs149946443, rs751625334, rs746860114, rs763444110, rs753656531, rs140853603, rs756398963, rs745335257, rs771045819, rs373011242, rs1563110498, rs779708902, rs760613621, rs1257462759, rs753335214, rs1479087781, rs763151288, rs2535245031, rs2535245025, rs761159568, rs769368151, rs2535302956, rs1332713722, rs1450438768, rs1812683938, rs1447616097, rs2484598762, rs2484598767, rs1410587848, rs2535300980, rs2535218674, rs1795371147, rs753301970, rs2484671748, rs759803761, rs748206350, rs775472696, rs2535218804, rs1284895808, rs1252623150, rs1813174207, rs1436907898, rs767427358, rs1167977173, rs2535240072, rs2484676376, rs757829658, rs939803784, rs373789155, rs1161253827, rs2484688451, rs2535247481, rs2535278574, rs1191923442, rs2484689667, rs2535312156, rs2484695015, rs1407025000, rs749031818, rs1167465422, rs2484820521, rs1313880486, rs2535259064, rs2484689730, rs2535269498, rs369702920, rs2535300796, rs1797963116, rs1368023264, rs1360292141, rs2484692953, rs2484721460, rs1240000701, rs2535246211, rs781128255, rs2484750502, rs759296167, rs1177772169, rs1254426170, rs2535203926, rs1404750488, rs2484750436, rs770332643, rs1263755495, rs1031986925, rs1027760188, rs1400955269, rs1799174248, rs771803411, rs766454113, rs150527358, rs2484808770, rs1267250420, rs548992583, rs775430597, rs774276502, rs754149796, rs767908447, rs2535302573, rs2535247216, rs2484688736, rs2484671617, rs1281472029, rs751135212, rs1370987227, rs1186742224, rs1813193919, rs1276348861, rs763664936, rs1315830175, rs371461279, rs770246714, rs1479901490, rs2535165611, rs2535258511, rs2484808703, rs1799184253, rs140934835, rs758400476, rs754329751, rs765976119, rs142125596, rs78221443, rs764066037, rs769653270, rs780599681, rs189151663, rs376961682, rs767245893, rs776353922, rs2535259095, rs1815169853, rs747011533, rs1941492100, rs1799233867, rs1258121574, rs886062468, rs776582090, rs151197146, rs200844952, rs886062477, rs886062479, rs751615449, rs2535246869, rs527735002, rs372172519, rs2535299890, rs1209079493, rs146831402, rs374280470, rs751002727, rs886062474, rs147841245, rs200711005, rs138928104, rs775673048, rs138739292, rs1813783655, rs767204829, rs2484807687, rs1478936254, rs767324244, rs1180483368, rs746403215, rs767298163, rs557980103, rs568497742, rs2535300343, rs769833170, rs1158336906, rs1195627112, rs1258173137, rs761190206, rs1188686549, rs137892407, rs2484692133, rs2484622631, rs767035326, rs1490689068, rs1554422424, rs1806324619, rs377157172, rs1413683928, rs1343554455, rs769113364, rs1374385673, rs755491238, rs2484688649, rs770593631, rs2535301573, rs1816924939, rs2535308675, rs2535308732, rs1194616736, rs2535311906, rs779331135, rs1402356971, rs2535327187, rs1425583842, rs765201611, rs1355598014, rs2484689298, rs766537510, rs781602762, rs2484598663, rs2484689985, rs2484690186, rs754559990, rs149977450, rs2484691423, rs1429267561, rs2484692506, rs2484692824, rs775411707, rs2484599149, rs1033544238, rs748910186, rs2484695163, rs2484599325, rs1261831665, rs2484695978, rs2484696342, rs576475484, rs2484696781, rs2484697047, rs1799379984, rs148905984, rs969969451, rs764576466, rs2484725857, rs760961518, rs375200151, rs757874090, rs377136514, rs752092340, rs2484734049, rs765586191, rs2130716370, rs752180431, rs757027446, rs1802548589, rs1447947098, rs2484786965, rs1411463397, rs372398605, rs2484808792, rs1255291282, rs1314047305, rs377264390, rs2535164762, rs1342889309, rs1418213201, rs199631609, rs2535165522, rs2535191147, rs2535194837, rs776612633, rs2535194965, rs762337629, rs2535203699, rs1477894196, rs2535208088, rs2535218377, rs1180706651, rs2484671475, rs909236475, rs2535240359, rs745520352, rs781407265, rs770514359, rs2130860986, rs766291027, rs2535244908, rs746200047, rs1449439204, rs2535246532, rs2535246549, rs1813255105, rs878854810, rs1471648697, rs866236214, rs2535258169, rs2535258525, rs754777973, rs781238898, rs2535264271, rs2535264277, rs752802080, rs1814409672, rs374537447, rs756856124, rs1459451500, rs746900083, rs2535278443, rs1295492727, rs1269032462, rs1364235653, rs2535299380, rs976804494, rs1057521238, rs570384292, rs1060503553, rs1060504956, rs951438275, rs376950905, rs138390702, rs755140795, rs144269839, rs147772200, rs139963188, rs368444006, rs140782750, rs142610139, rs1060503580, rs371316172, rs747049411, rs752685614, rs377663331, rs138107415, rs138567837, rs568626378, rs115624293, rs142251048, rs149341527, rs891249707, rs749340561, rs777349648, rs757261572, rs752977579, rs143565222, rs375778014, rs779280501, rs963431431, rs149979685, rs756185133, rs777495335, rs147302252, rs746045284, rs374340343, rs1265369157, rs538621911, rs776992805, rs1554451226, rs749572064, rs185491437, rs759783541, rs776451600, rs779022140, rs142263098, rs1554435236, rs1000673132, rs142573103, rs138049714, rs187255726, rs760173622, rs747689685, rs1554430888, rs575158854, rs770573236, rs767137372, rs138765069, rs200730225, rs1422124687, rs1554367029, rs145936668, rs186969744, rs1554399721, rs142632541, rs148852801, rs768274954, rs143717354, rs368967178, rs146022334, rs936298117, rs375876545, rs1554404018, rs371085808, rs748637545, rs374700234, rs374455304, rs1252942288, rs1554404361, rs368006874, rs144918888, rs759926255, rs775917820, rs775799706, rs1554405166, rs551552300, rs1554405607, rs749254312, rs150875198, rs1309731483, rs760043880, rs762203528, rs565975524, rs184184931, rs1554426900, rs1400302163, rs1554430832, rs970122684, rs369082700, rs754481023, rs150102469, rs146854871, rs1554450960, rs1426533488, rs375175124, rs1554454272, rs775741227, rs148799606, rs150579291, rs756495468, rs765533928, rs61757675, rs372493917, rs377026066, rs1297567039, rs752031242, rs138566065, rs538476247, rs781296769, rs201298286, rs769686940, rs757123477, rs141094356, rs1455029822, rs61757667, rs771190405, rs1315064294, rs377561989, rs750905383, rs1330827109, rs201545032, rs551316515, rs192845338, rs1431417772, rs754943177, rs185594755, rs753029277, rs1004449825, rs372955225, rs796565514, rs781775348, rs565812419, rs1274983523, rs61757674, rs760860769, rs772669837, rs1563145763, rs368059326, rs201558875, rs780099038, rs1562958328, rs1563041499, rs768512576, rs529180209, rs1006205177, rs1463067477, rs377611430, rs539375675, rs368823780, rs199909093, rs1563142906, rs746612786, rs774013935, rs774110970, rs752618658, rs1563113459, rs750921440, rs1279150801, rs989895553, rs751926047, rs1029311669, rs546600149, rs779325943, rs141987389, rs746465984, rs763089587, rs200044616, rs776780461, rs769085707, rs777752444, rs749345540, rs536744826, rs748899639, rs1407994937, rs1554453992, rs763275190, rs779260877, rs746297415, rs772348877, rs368263036, rs758717247, rs747162821, rs982934060, rs373321787, rs779232513, rs537499946, rs148146011, rs371957004, rs759646439, rs1042630361, rs143473598, rs142092767, rs370346906, rs745393946, rs1336731619, rs747269042, rs761387563, rs780002980, rs143138024, rs200050078, rs762012353, rs768773867, rs762890144, rs777561134, rs761644697, rs748229690, rs1215615118, rs746815931, rs759286117, rs751653287, rs771419309, rs376528503, rs146864466, rs368162150, rs887210886, rs1447648184, rs1426532950, rs369206894, rs765992335, rs746335356, rs767728528, rs377560937, rs1221445886, rs1253028052, rs756905236, rs1463340231, rs1372778218, rs1304374666, rs757454990, rs970740445, rs746874048, rs143967328, rs372748115, rs745743634, rs890787072, rs367598698, rs763748052, rs147033628, rs901965564, rs371599265, rs373313419, rs916216692, rs1376036983, rs759219564, rs369522150, rs199880764, rs377559019, rs893173151, rs1425297084, rs190695638, rs145355395, rs138535219, rs149162273, rs757679497, rs201184315, rs755931396, rs1217996637, rs1810610818, rs780111217, rs149819328, rs773726579, rs961090757, rs1818400785, rs748330070, rs1283390674, rs746429266, rs1169980644, rs774423206, rs773257553, rs1810599049, rs759474634, rs561591139, rs1198428381, rs184676617, rs757278868, rs141103974, rs200288508, rs1816925987, rs1175318913	RCV003382524 RCV005340785 RCV002412016 RCV005851813 RCV002341635 RCV002329298 RCV002327694 RCV002341667 RCV002341664 RCV002350570 RCV002375412 RCV002384422 RCV004034341 RCV004035162 RCV002438704 RCV003294299 RCV005851833 RCV005330716 RCV002368116 RCV003294331 RCV002341706 RCV002357179 RCV003169640 RCV003382541 RCV002447406 RCV002377489 RCV002395779 RCV002322280 RCV002432002 RCV002350679 RCV003382565 RCV005340851 RCV004037552 RCV003298578 RCV004619675 RCV004629608 RCV004036803 RCV002368170 RCV002368167 RCV002420777 RCV006352219 RCV004036999 RCV004995706 RCV002420842 RCV004995710 RCV003169837 RCV004995763 RCV002395938 RCV002358906 RCV006352245 RCV002358922 RCV002368285 RCV004995788 RCV002322420 RCV006352256 RCV006352259 RCV003298749 RCV003298710 RCV005572592 RCV002350865 RCV002350879 RCV006352268 RCV002377672 RCV002449198 RCV003284326 RCV002439005 RCV003382592 RCV004037177 RCV002322512 RCV004995851 RCV005841805 RCV002329549 RCV002342015 RCV002342065 RCV004631717 RCV002329525 RCV002456870 RCV005341003 RCV002456838 RCV002334545 RCV002343668 RCV002359137 RCV002359095 RCV002359121 RCV002368515 RCV002377830 RCV002384837 RCV002432370 RCV002439149 RCV002456860 RCV003298911 RCV002324116 RCV004037884 RCV005341018 RCV002334578 RCV002359152 RCV005341020 RCV003382630 RCV004995966 RCV004039556 RCV002343794 RCV005572625 RCV002370265 RCV002370266 RCV002343806 RCV005341035 RCV004046107 RCV003382729 RCV002352709 RCV004043316 RCV004043321 RCV003167153 RCV002407206 RCV005343284 RCV002449548 RCV005572738 RCV002388957 RCV005572657 RCV002422906 RCV002359413 RCV002370708 RCV005841901 RCV004996105 RCV002370627 RCV002370452 RCV004631826 RCV005341096 RCV002423047 RCV002324484 RCV002329778 RCV004040601 RCV002331425 RCV002449554 RCV002361366 RCV002386618 RCV002361120 RCV005572686 RCV004996109 RCV003303474 RCV002370459 RCV006352552 RCV004990522 RCV002331514 RCV000251706 RCV000618857 RCV000249103 RCV003352776 RCV000619447 RCV000248579 RCV000251839 RCV000619879 RCV000252649 RCV004043870 RCV000244445 RCV000248223 RCV000249606 RCV000248916 RCV000618431 RCV000244317 RCV000618866 RCV000243269 RCV000243921 RCV003382798 RCV002324335 RCV002370405 RCV002359399 RCV002370553 RCV004045210 RCV005841954 RCV003382727 RCV002331513 RCV005841858 RCV002370532 RCV002352645 RCV002458978 RCV002386760 RCV002344012 RCV004043885 RCV005841860 RCV002370538 RCV005841862 RCV004045318 RCV002386893 RCV003382695 RCV004041631 RCV002449510 RCV002386901 RCV003303588 RCV005343280 RCV002370484 RCV002442994 RCV004990533 RCV002324219 RCV002343993 RCV003303431 RCV004990532 RCV004045474 RCV002425207 RCV005572704 RCV005841881 RCV005854163 RCV002361207 RCV002372806 RCV004996070 RCV005572718 RCV002441178 RCV003164130 RCV006352586 RCV002359390 RCV002334917 RCV005841865 RCV005851994 RCV004996035 RCV002449568 RCV003167111 RCV002442897 RCV004996091 RCV004042736 RCV004631882 RCV004039150 RCV002388777 RCV002370525 RCV002407108 RCV002425234 RCV004042943 RCV005841917 RCV002458655 RCV002423122 RCV002458651 RCV006357156 RCV005330975 RCV002324370 RCV003382755 RCV002337159 RCV003170427 RCV002386921 RCV002335030 RCV002427608 RCV002346350 RCV002434568 RCV002352823 RCV004045817 RCV004046553 RCV005574897 RCV005841966 RCV002352828 RCV004616984 RCV002352900 RCV003161625 RCV003307949 RCV005343356 RCV003307990 RCV002363645 RCV004045806 RCV002324565 RCV002346419 RCV003307979 RCV002398192 RCV003308048 RCV002331729 RCV002443102 RCV002363686 RCV005574904 RCV003161535 RCV002391314 RCV002372868 RCV003161549 RCV002454546 RCV004047207 RCV002373050 RCV002434606 RCV002443284 RCV003308122 RCV002319775 RCV002319780 RCV002319782 RCV002319802 RCV002319810 RCV002319826 RCV002325837 RCV002325901 RCV002325926 RCV002325989 RCV002324702 RCV002324740 RCV002324763 RCV002451828 RCV002444648 RCV000621526 RCV004019890 RCV000619474 RCV002381505 RCV006342132 RCV002453527 RCV002452032 RCV002337607 RCV002454830 RCV002454875 RCV002454973 RCV002454978 RCV002349142 RCV002349222 RCV002357460 RCV002373159 RCV002373166 RCV002321396 RCV002321422 RCV002323053 RCV002327991 RCV002328060 RCV002328124 RCV002322912 RCV002326498 RCV002326536 RCV002459351 RCV002452613 RCV002346679 RCV002457431 RCV002355395 RCV002359433 RCV002359457 RCV002375736 RCV002321182 RCV002321242 RCV002321336 RCV002333370 RCV002333429 RCV002327841 RCV002327851 RCV002327854 RCV002333649 RCV002333755 RCV002320754 RCV002320778 RCV002322534 RCV002326186 RCV002326320 RCV002457180 RCV002460236 RCV002337495 RCV002457285 RCV002457288 RCV002452261 RCV002452278 RCV002452364 RCV002460341 RCV002452441 RCV002363928 RCV002363958 RCV002363970 RCV002355225 RCV002363991 RCV002357733 RCV002375543 RCV002375561 RCV002375663 RCV002332154 RCV002332170 RCV002332270 RCV002445632 RCV002324942 RCV002324981 RCV002325027 RCV002445729 RCV002455000 RCV002351140 RCV002351147 RCV002351177 RCV002373172 RCV002373247 RCV002357652 RCV002333154 RCV002330143 RCV002330159 RCV002330222 RCV002331932 RCV002333913 RCV002333949 RCV002328424 RCV002330499 RCV002335188 RCV002335215 RCV002335221 RCV002335240 RCV002335263 RCV002351224 RCV002351265 RCV002340743 RCV002342682 RCV002342770 RCV002338323 RCV002338324 RCV002338332 RCV002349499 RCV002349529 RCV002349726 RCV002349821 RCV002349824 RCV002349874 RCV002347518 RCV002349974 RCV002356163 RCV002357862 RCV002357896 RCV002358135 RCV002358240 RCV002358244 RCV002368718 RCV002353941 RCV002353942 RCV002368810 RCV002353987 RCV002342407 RCV002342415 RCV002342479 RCV002342533 RCV002342534 RCV002342564 RCV002330419 RCV002342616 RCV002340320 RCV002335968 RCV002344220 RCV002344230 RCV002347002 RCV002345095 RCV002345114 RCV002345153 RCV002347334 RCV002355756 RCV002355948 RCV002355991 RCV002356060 RCV002356105 RCV002353858 RCV002366580 RCV002366724 RCV002368658 RCV002364196 RCV002364338 RCV002364376 RCV002364387 RCV002364474 RCV002340220 RCV002342164 RCV002342165 RCV002337900 RCV002337943 RCV002338112 RCV002335762 RCV002344710 RCV002344911 RCV002353360 RCV002353587 RCV002353596 RCV002360285 RCV002360409 RCV002360425 RCV002361875 RCV002356231 RCV002369198 RCV002377951 RCV002328587 RCV002339873 RCV002335437 RCV002335531 RCV002330631 RCV002337760 RCV002330700 RCV002337794 RCV002351348 RCV002340911 RCV002351915 RCV002359667 RCV002359679 RCV002359684 RCV002359905 RCV002353116 RCV002369045 RCV002369093 RCV002369095 RCV002354076 RCV002354105 RCV002361643 RCV002375792 RCV002375809 RCV002366759 RCV002366762 RCV002366791 RCV002366861 RCV002366884 RCV002362443 RCV002362444 RCV002370986 RCV002382553 RCV002382602 RCV002382732 RCV002393960 RCV002393980 RCV002394045 RCV002394085 RCV002394124 RCV002394126 RCV002416820 RCV002416840 RCV002416930 RCV002419053 RCV002434675 RCV002434682 RCV002434723 RCV002434829 RCV002434832 RCV002434836 RCV002373570 RCV002373787 RCV002371247 RCV002371265 RCV002371399 RCV002450069 RCV002371490 RCV002369654 RCV002378021 RCV002378345 RCV002378375 RCV002378378 RCV002370755 RCV002391470 RCV002391581 RCV002391638 RCV002393776 RCV002393803 RCV002393832 RCV002393901 RCV002409988 RCV002409995 RCV002412097 RCV002427950 RCV002412506 RCV002427992 RCV002428023 RCV002428025 RCV002430226 RCV002449661 RCV002449980 RCV002378657 RCV002378749 RCV002378840 RCV002385258 RCV002385260 RCV002376467 RCV002385343 RCV002369500 RCV002378308 RCV002367294 RCV002367298 RCV002367422 RCV002384895 RCV002385035 RCV002385126 RCV002409890 RCV002419543 RCV002421383 RCV002421403 RCV002427818 RCV002447730 RCV002414444 RCV002448006 RCV002448020 RCV002376411 RCV002376440 RCV002376441 RCV002378508 RCV002378515 RCV002378566 RCV002443516 RCV002374226 RCV002374232 RCV002374310 RCV002385202 RCV002377928 RCV002364803 RCV002382749 RCV002380027 RCV002380077 RCV002380360 RCV002396368 RCV002400599 RCV002400600 RCV002419336 RCV002419408 RCV002419452 RCV002412601 RCV002412606 RCV002376013 RCV002376019 RCV002376077 RCV002376105 RCV002376143 RCV002376144 RCV002376243 RCV002450109 RCV002443391 RCV002373944 RCV002374015 RCV002387046 RCV002387063 RCV002376740 RCV002387084 RCV002387089 RCV002376803 RCV002382963 RCV002382964 RCV002383047 RCV002405793 RCV002398348 RCV002398361 RCV002403770 RCV002401506 RCV002376850 RCV002376854 RCV002387273 RCV002387318 RCV002387339 RCV002387372 RCV002382842 RCV002382861 RCV002382872 RCV002382936 RCV002382939 RCV002387619 RCV002387631 RCV002405722 RCV002405748 RCV002395008 RCV002399079 RCV002399157 RCV002399233 RCV002410112 RCV002410122 RCV002410291 RCV002410367 RCV002381217 RCV002396575 RCV002389073 RCV002389177 RCV002396784 RCV002396909 RCV002403205 RCV002403238 RCV002403324 RCV002401216 RCV002401288 RCV002403481 RCV002398991 RCV002404128 RCV002404146 RCV002407731 RCV002404252 RCV002407846 RCV002407884 RCV002415183 RCV002380613 RCV002380834 RCV002380931 RCV002383599 RCV002381122 RCV002394387 RCV002394443 RCV002394640 RCV002400881 RCV002406079 RCV002414981 RCV002412769 RCV002412813 RCV002412860 RCV002412923 RCV002423415 RCV002423429 RCV002423637 RCV002423638 RCV002417901 RCV002432785 RCV002457901 RCV002459543 RCV002431083 RCV002431084 RCV002455644 RCV002434916 RCV002432994 RCV002437264 RCV002452984 RCV002452996 RCV002408172 RCV002408273 RCV002413263 RCV002413297 RCV002419853 RCV002421912 RCV002430595 RCV002432574 RCV002443643 RCV002443678 RCV002457708 RCV002450120 RCV002450189 RCV002455555 RCV002450624 RCV002430987 RCV002437098 RCV002426311 RCV002437203 RCV002437207 RCV002417380 RCV002419619 RCV002419715 RCV002417644 RCV002417686 RCV002455397 RCV002455404 RCV002433418 RCV002452791 RCV002426066 RCV002437360 RCV002423810 RCV002417208 RCV002417221 RCV002424166 RCV002424184 RCV002425512 RCV002425647 RCV002457499 RCV002446247 RCV002428487 RCV002428515 RCV002453104 RCV002428731 RCV002453139 RCV002441455 RCV002441698 RCV002441745 RCV002435001 RCV002439449 RCV002439565 RCV002439737 RCV002440045 RCV002440235 RCV002440243 RCV002441835 RCV002441860 RCV002441998 RCV002431336 RCV002437580 RCV002439371 RCV002439887 RCV002438161 RCV002444011 RCV002444148 RCV002444212 RCV002435179 RCV002435217 RCV002435233 RCV002435312 RCV002435396 RCV002437628 RCV002435845 RCV002435937 RCV002442132 RCV002442134 RCV002442221 RCV002435552 RCV000618639 RCV005575069 RCV004070346 RCV003383002 RCV003383004 RCV005575055 RCV004992461 RCV003294472 RCV004071867 RCV006342781 RCV002453573 RCV003352791 RCV003278674 RCV002433729 RCV003162726 RCV000242948 RCV000251693 RCV002362867 RCV003162727 RCV000620147 RCV000251195 RCV000248835 RCV000621504 RCV002336389 RCV002326932 RCV002336390 RCV002336391 RCV000620424 RCV002362866 RCV004020023 RCV000617996 RCV002381540 RCV000250287 RCV000253746 RCV002345571 RCV004632176 RCV005575080 RCV005335639 RCV003161726 RCV004071990 RCV000254067 RCV005338092 RCV000621863 RCV000618946 RCV000619217 RCV002408741 RCV002426816 RCV000621677 RCV000245265 RCV002326937 RCV000247905 RCV000250219 RCV000243341 RCV000617198 RCV002336405 RCV002345578 RCV002345579 RCV000252240 RCV000250867 RCV000243812 RCV000253231 RCV002408742 RCV002415728 RCV000241571 RCV002372067 RCV000620913 RCV005572279 RCV000619253 RCV002372068 RCV000243508 RCV002381554 RCV000248840 RCV000250716 RCV004020046 RCV000619518 RCV002415730 RCV000619885 RCV000617326 RCV002433743 RCV000248078 RCV002321683 RCV002326938 RCV003161754 RCV004634180 RCV004634181 RCV005333542 RCV003294575 RCV004070810 RCV003294601 RCV004070594 RCV000617636 RCV003162129 RCV003384353 RCV005333568 RCV003308143 RCV003382890 RCV003164817 RCV004064380 RCV005854245 RCV004990787 RCV004065566 RCV006357479 RCV004066620 RCV004990835 RCV003167693 RCV004064757 RCV004064723 RCV004064724 RCV003382940 RCV004990878 RCV005575003 RCV002336077 RCV003167895 RCV003382971 RCV004067150 RCV003170635 RCV003170653 RCV002390537 RCV004629166 RCV000248585 RCV000243061 RCV002408883 RCV004990930 RCV006342666 RCV004632146 RCV004068446 RCV004990962 RCV003382991 RCV004632148 RCV004068609 RCV004990975 RCV004068685 RCV005854386 RCV004070994 RCV000246934 RCV002319461 RCV000618805 RCV000246728 RCV004106717 RCV002408902 RCV000622053 RCV005338111 RCV004108544 RCV004108568 RCV004116860 RCV004117064 RCV004136500 RCV004146493 RCV004143033 RCV004140079 RCV004140772 RCV004158496 RCV004150336 RCV004170940 RCV004179495 RCV004180138 RCV004178024 RCV000250014 RCV003298286 RCV002365201 RCV004992110 RCV002418015 RCV000617362 RCV002429119 RCV000618814 RCV002338738 RCV000619619 RCV002401892 RCV005841534 RCV002444903 RCV006342190 RCV000621715 RCV004246151 RCV003171729 RCV003171730 RCV003171731 RCV003171244 RCV003171732 RCV003171733 RCV003171245 RCV003171734 RCV003171246 RCV003171735 RCV003171736 RCV003171737 RCV003171247 RCV003171738 RCV003171248 RCV003171739 RCV003171740 RCV003171741 RCV003171742 RCV003171743 RCV003171744 RCV003171745 RCV003171746 RCV003171747 RCV003171748 RCV003171249 RCV003171250 RCV003171749 RCV003171750 RCV003171251 RCV003171751 RCV003171752 RCV003171753 RCV003171754 RCV003171755 RCV003171756 RCV003171252 RCV003171757 RCV003171758 RCV003171759 RCV003171761 RCV003171762 RCV003171763 RCV003171764 RCV003171765 RCV003171253 RCV003171254 RCV003171766 RCV003171767 RCV003171768 RCV003171255 RCV003171256 RCV003171769 RCV003171257 RCV003171770 RCV003171771 RCV003171258 RCV003171259 RCV003171260 RCV003171772 RCV003171261 RCV003171773 RCV003171774 RCV003171262 RCV003171263 RCV003171775 RCV003171776 RCV003171777 RCV003177564 RCV003177583 RCV004259637 RCV004257556 RCV004265668 RCV004274417 RCV003213811 RCV003213812 RCV003213813 RCV003213814 RCV004285618 RCV000251328 RCV000252299 RCV000254245 RCV000248212 RCV000245713 RCV000251578 RCV000247931 RCV000250842 RCV000248302 RCV000248261 RCV000248203 RCV000247725 RCV000242820 RCV000249884 RCV000251084 RCV000242971 RCV000249869 RCV000244190 RCV000245408 RCV000252879 RCV000246887 RCV000251256 RCV000252644 RCV000248997 RCV000247946 RCV000251850 RCV000245232 RCV000251135 RCV000243591 RCV000243700 RCV000254339 RCV000249384 RCV000249122 RCV004287520 RCV004286436 RCV004295615 RCV004314064 RCV004321604 RCV004309090 RCV004308761 RCV003296235 RCV003296236 RCV003288274 RCV003296238 RCV003296239 RCV003288275 RCV004322802 RCV003305781 RCV003305782 RCV003305784 RCV003305786 RCV003305787 RCV003310943 RCV003310944 RCV003310945 RCV003310946 RCV003310947 RCV003310948 RCV003310950 RCV003310951 RCV003310952 RCV003310953 RCV003310954 RCV003310955 RCV003310957 RCV003310958 RCV003310959 RCV003310960 RCV003310961 RCV003310962 RCV003310963 RCV003310964 RCV003310966 RCV003310967 RCV003310968 RCV003310969 RCV003310970 RCV003310971 RCV003310972 RCV003310974 RCV003310975 RCV003310976 RCV003310977 RCV003310978 RCV003310979 RCV003310981 RCV003310982 RCV003310983 RCV003310984 RCV003310985 RCV003310986 RCV003310988 RCV003310989 RCV004992589 RCV004333280 RCV003360622 RCV004353370 RCV004351527 RCV004355650 RCV004356773 RCV004356696 RCV003385829 RCV003385830 RCV003385831 RCV003385832 RCV003382255 RCV003382256 RCV003382257 RCV003382258 RCV003382259 RCV003382260 RCV003382261 RCV003382262 RCV003382263 RCV003382264 RCV003382265 RCV003382267 RCV003382268 RCV003382269 RCV003382270 RCV003382271 RCV003382272 RCV003382273 RCV003382274 RCV003382275 RCV003382276 RCV003382277 RCV003382278 RCV003382279 RCV003382281 RCV003382282 RCV003382283 RCV003382284 RCV003382285 RCV003382287 RCV003382288 RCV005335789 RCV004369085 RCV005575187 RCV005844271 RCV004992641 RCV005335799 RCV004992659 RCV004992663 RCV004369317 RCV004992661 RCV004371562 RCV004371659 RCV005844279 RCV004371751 RCV006347794 RCV004371917 RCV004992732 RCV004373902 RCV002402074 RCV002446612 RCV000619407 RCV002338951 RCV003168562 RCV004992185 RCV002446614 RCV000620601 RCV004374003 RCV005854562 RCV004992750 RCV005575216 RCV004992773 RCV005856548 RCV004374207 RCV006347839 RCV005338158 RCV002374599 RCV000618070 RCV000620066 RCV002446613 RCV005572309 RCV004022059 RCV006347846 RCV004374277 RCV005335903 RCV005335895 RCV004992806 RCV000619602 RCV003168561 RCV002328877 RCV004022058 RCV002348112 RCV002365424 RCV000620597 RCV002356490 RCV002365423 RCV000619531 RCV000619623 RCV004634365 RCV004366757 RCV005575246 RCV004366846 RCV005335942 RCV004366906 RCV004634379 RCV004366912 RCV004992923 RCV004992924 RCV004634392 RCV004634396 RCV004992933 RCV004992937 RCV004992925 RCV005575255 RCV004369577 RCV004402121 RCV004402167 RCV004402194 RCV004402216 RCV004402226 RCV004402229 RCV004402238 RCV004402312 RCV004402346 RCV004402351 RCV004521685 RCV004521686 RCV004521687 RCV004521688 RCV004521689 RCV004521690 RCV004521691 RCV004521692 RCV004521693 RCV004521694 RCV004521695 RCV004521696 RCV004521697 RCV004521698 RCV004521699 RCV004521700 RCV004521701 RCV004521702 RCV004521703 RCV004521704 RCV004521705 RCV004521706 RCV004521707 RCV004521708 RCV004521709 RCV004521710 RCV004521711 RCV004521712 RCV004521713 RCV004521714 RCV004521715 RCV004521716 RCV004521717 RCV004521718 RCV004521719 RCV004521720 RCV004521721 RCV004521722 RCV004521723 RCV004521724 RCV004521725 RCV004521727 RCV004521728 RCV004521729 RCV004521730 RCV004521731 RCV004521732 RCV004521733 RCV004521734 RCV004521735 RCV004521736 RCV004521737 RCV004521738 RCV004521739 RCV004521740 RCV004521741 RCV004521742 RCV004521743 RCV004521744 RCV004521745 RCV004521746 RCV004521747 RCV004521748 RCV004521749 RCV004521750 RCV004521751 RCV004521752 RCV004521753 RCV004521754 RCV004521755 RCV004521756 RCV004521757 RCV004521758 RCV004521759 RCV004521760 RCV004521761 RCV004521762 RCV004521763 RCV004521764 RCV004521765 RCV004521766 RCV004521767 RCV004521768 RCV004521769 RCV004521770 RCV004521771 RCV004521772 RCV004521773 RCV004523735 RCV004523736 RCV004523737 RCV004523738 RCV004523739 RCV004523740 RCV004523741 RCV004523742 RCV004523743 RCV004523744 RCV004523745 RCV004523746 RCV004523747 RCV004523748 RCV004523749 RCV004523750 RCV004523751 RCV004523752 RCV004523753 RCV004523754 RCV004523755 RCV004523756 RCV004523757 RCV004523758 RCV004523759 RCV004523760 RCV004523761 RCV004523762 RCV004523763 RCV004523764 RCV004523765 RCV004523766 RCV002348182 RCV002339000 RCV005572318 RCV002350043 RCV000621312 RCV005338186 RCV002356758 RCV000619225 RCV002329081 RCV002339191 RCV003298510 RCV002356759 RCV000620675 RCV000618311 RCV000621390 RCV003168863 RCV000622221 RCV002374875 RCV004022894 RCV002402368 RCV002436521 RCV000622237 RCV002339190 RCV002350044 RCV000621785 RCV003168930 RCV002446913 RCV002383833 RCV000621830 RCV004992270 RCV002329173 RCV002329209 RCV002395223 RCV002330831 RCV002330830 RCV002350182 RCV000617535 RCV004023769 RCV000620706 RCV004992320 RCV005841594 RCV002384056 RCV004619320 RCV002438304 RCV002323921 RCV002350186 RCV002367780 RCV006342345 RCV002395298 RCV003302784 RCV002323920 RCV002341268 RCV002420362 RCV006342344 RCV002350183 RCV002350185 RCV002350187 RCV002448630 RCV002413453 RCV004629235 RCV002438303 RCV000620609 RCV004992321 RCV004023768 RCV002350184 RCV002413454 RCV002404580 RCV004024588 RCV002334011 RCV002350466 RCV000620386 RCV000619575 RCV000619915 RCV000621808 RCV000617610 RCV000620708 RCV000619153 RCV000621192 RCV000619608 RCV000621539 RCV000617314 RCV000619621 RCV000620623 RCV000621953 RCV000620345 RCV000620509 RCV000619091 RCV000617528 RCV000621262 RCV000618207 RCV000620320 RCV000620916 RCV000621782 RCV000619612 RCV000620471 RCV000618837 RCV000619704 RCV000621926 RCV000619856 RCV000619053 RCV000620410 RCV000620234 RCV000621080 RCV000619743 RCV000621247 RCV000619763 RCV000620615 RCV000618543 RCV000618469 RCV000620775 RCV000619530 RCV000620565 RCV000617780 RCV000617453 RCV000617688 RCV000618855 RCV000620955 RCV000619574 RCV000617216 RCV000618060 RCV000622175 RCV000619107 RCV000618512 RCV000618211 RCV000617444 RCV000619402 RCV000621479 RCV000619074 RCV000620749 RCV000617618 RCV000619170 RCV000618576 RCV000618862 RCV000620944 RCV000619908 RCV000620823 RCV000617515 RCV000617539 RCV002448912 RCV002377333 RCV002343178 RCV002404744 RCV005572347 RCV002448938 RCV002343210 RCV002360508 RCV003302989 RCV002420683 RCV002331111 RCV002360507 RCV003162802 RCV002385984 RCV004025410 RCV002457996 RCV002325214 RCV002360511 RCV002388013 RCV003380645 RCV002360515 RCV002420684 RCV002358767 RCV002358764 RCV002385983 RCV002438655 RCV004025404 RCV002334221 RCV003163081 RCV002334300 RCV005572366 RCV004993945 RCV005841613 RCV004026389 RCV002352185 RCV002440476 RCV002369930 RCV002422608 RCV004026521 RCV005572363 RCV002369884 RCV004025130 RCV002360728 RCV002406598 RCV002406588 RCV005328383 RCV005572377 RCV002325457 RCV004993991 RCV003166009 RCV004994020 RCV005572383 RCV003169011 RCV002442701 RCV005338370 RCV002325571 RCV004028266 RCV002336684 RCV002336634 RCV003362944 RCV002334465 RCV002336706 RCV003166175 RCV002352457 RCV005338380 RCV002360934 RCV005851612 RCV002381855 RCV005572392 RCV002422782 RCV005851625 RCV002442673 RCV002370160 RCV006342553 RCV002370174 RCV002370138 RCV004028849 RCV002381867 RCV003307541 RCV003166102 RCV002440632 RCV002363178 RCV002319935 RCV002336731 RCV002345930 RCV003307576 RCV002345937 RCV002363202 RCV002336760 RCV002442793 RCV002372418 RCV002352547 RCV005572405 RCV004994088 RCV002381957 RCV002390769 RCV003307623 RCV002372457 RCV002453960 RCV002427181 RCV002332824 RCV003169193 RCV002409097 RCV003169267 RCV002372557 RCV004029462 RCV002445081 RCV004030245 RCV002346206 RCV002416285 RCV002363530 RCV002445156 RCV006355901 RCV002402452 RCV002429621 RCV003160223 RCV002429742 RCV002436551 RCV002436684 RCV002451262 RCV003307820 RCV002348445 RCV002348349 RCV004030487 RCV002409415 RCV003307819 RCV004031722 RCV002372794 RCV002379502 RCV002379535 RCV004629427 RCV002320286 RCV004994252 RCV002445412 RCV002375056 RCV004629480 RCV002365889 RCV002447037 RCV005841721 RCV002322084 RCV002451439 RCV002436809 RCV002327467 RCV002327476 RCV002348688 RCV002402597 RCV002402615 RCV002322012 RCV002339536 RCV004033762 RCV005340691 RCV002436909 RCV005841739 RCV005572503 RCV002366060 RCV002411890 RCV005340713 RCV002322149 RCV002327576 RCV002357043 RCV005340720 RCV002375264 RCV002379951 RCV002418830 RCV005340725 RCV002418861 RCV002322171 RCV002393694 RCV002402858 RCV003382508 RCV004036273 RCV003294249 RCV002327631 RCV002357101 RCV002366140 RCV002366138 RCV002366141 RCV002366120 RCV002402872 RCV002375353 RCV004036373 RCV004629550 RCV003382510 RCV002350552
Catecholaminergic polymorphic ventricular tachycardia	Conflicting classifications of pathogenicity	rs144888041	RCV000853011
Cervical cancer	Likely benign; Conflicting classifications of pathogenicity; Uncertain significance	rs757310407, rs145033147, rs760961518	RCV005912782 RCV005889667 RCV005939432
Cholangiocarcinoma	Uncertain significance; Likely benign; Benign	rs747360879, rs772968330, rs10257832	RCV005934823 RCV005901250 RCV005903883
Colon adenocarcinoma	Conflicting classifications of pathogenicity	rs146831402	RCV005899269
Colorectal cancer	Benign	rs6964587	RCV000171778
Congenital long QT syndrome	Benign; Likely benign; Conflicting classifications of pathogenicity; Uncertain significance	rs2230768, rs10236397, rs733957, rs35759833, rs6960867, rs10228334, rs1063242, rs28927678, rs1063243, rs1989779, rs13245393, rs139965373, rs151021935, rs755408339, rs144888041, rs534185372, rs10644111, rs140470576, rs139046510, rs35669569, rs367857951, rs60031334, rs61757557, rs146797353, rs139612565, rs73407505, rs61757671, rs73226383, rs201977551, rs78351282, rs34956633, rs61757664, rs144054367, rs142729919, rs143306820, rs200327385, rs77447750, rs139770404, rs78515732, rs143712699, rs147494754, rs80191629, rs141039834, rs150332727, rs775991910, rs146710448, rs34370932, rs756398963, rs886062464, rs142125596, rs886062469, rs78221443, rs73403768, rs764066037, rs769653270, rs780599681, rs886062475, rs554984079, rs886062478, rs189151663, rs376961682, rs767245893, rs762931104, rs886062463, rs886062465, rs532128328, rs886062468, rs886062472, rs776582090, rs151197146, rs200844952, rs375657019, rs886062476, rs886062477, rs764732139, rs377532409, rs180926926, rs112467497, rs886062479, rs751615449, rs371245265, rs764753013, rs542223871, rs886062470, rs4727267, rs146831402, rs886062467, rs886062471, rs374280470, rs751002727, rs886062474, rs147841245, rs200711005, rs768384617, rs138928104, rs115270109, rs775673048, rs138739292, rs886062480, rs886062481, rs886062482, rs886062483	RCV000356670 RCV000398917 RCV000279126 RCV000306061 RCV000261848 RCV000341751 RCV000282743 RCV000310199 RCV000353938 RCV000388439 RCV000342249 RCV000302445 RCV000267992 RCV000362168 RCV000354957 RCV000303943 RCV000280223 RCV000351603 RCV000365126 RCV000407417 RCV000384780 RCV000296066 RCV000264374 RCV000278007 RCV000340819 RCV000402169 RCV000267059 RCV000358502 RCV000309341 RCV000347974 RCV000301532 RCV000361837 RCV000382450 RCV000279610 RCV000310251 RCV000370586 RCV000346721 RCV000328206 RCV000260119 RCV005863047 RCV000297662 RCV000330366 RCV000401333 RCV000383455 RCV000370654 RCV000320983 RCV000383341 RCV000343246 RCV000389947 RCV000365707 RCV000356880 RCV000298587 RCV000336078 RCV000311322 RCV000317260 RCV000288990 RCV000334232 RCV000369912 RCV000340650 RCV000317358 RCV000289614 RCV000333928 RCV000358705 RCV000271816 RCV000401695 RCV000379206 RCV000399538 RCV000331936 RCV000274391 RCV000370962 RCV000394468 RCV000336412 RCV000269240 RCV000319474 RCV000401315 RCV000357166 RCV000268295 RCV000322405 RCV000282286 RCV000373196 RCV000363979 RCV000284576 RCV000336359 RCV000325248 RCV000380555 RCV000380417 RCV000345420 RCV000349102 RCV000346490 RCV000308447 RCV000283253 RCV000294466 RCV000349420 RCV000301608 RCV000356054 RCV000374132 RCV000288501 RCV000338122 RCV000332448 RCV000307177 RCV000400313 RCV000370317 RCV000298063
Familial cancer of breast	Benign; Likely benign	rs142729919	RCV005889669
Gastric cancer	Conflicting classifications of pathogenicity; Likely benign; Benign	rs554984079, rs754481023, rs10257832	RCV005899270 RCV005900074 RCV005903882
Heart failure	Benign; Likely benign	rs35669569, rs150102469	RCV000853010 RCV000853020
Hepatocellular carcinoma	Uncertain significance; Benign	rs761946454, rs12538678	RCV005924124 RCV005902337
Hypertrophic cardiomyopathy	Benign; Likely benign; Conflicting classifications of pathogenicity; Uncertain significance	rs35669569, rs77447750, rs149341527, rs769718964	RCV000853010 RCV000853028 RCV000853022 RCV000497730
Long QT syndrome 1	Uncertain significance; Conflicting classifications of pathogenicity	rs730880044, rs146811417, rs377026066, rs1798317723, rs961090757, rs1818400785	RCV001256718 RCV001256722 RCV001256724 RCV001256721 RCV001256717 RCV001256716
Long QT syndrome 2	Likely benign	rs138161478	RCV000157099
Lung cancer	Benign; Likely benign	rs78515732, rs772968330	RCV005893694 RCV005901251
Malignant lymphoma, large B-cell, diffuse	Benign	rs12538678	RCV005902338
Malignant tumor of esophagus	Uncertain significance; Likely benign; Benign; Conflicting classifications of pathogenicity	rs752923990, rs768017962, rs142729919, rs192845338	RCV005911016 RCV005921113 RCV005889670 RCV005900122
Ovarian serous cystadenocarcinoma	Benign; Likely benign; Uncertain significance	rs142729919, rs767167128, rs777752444, rs558339511	RCV005889671 RCV005895311 RCV005902090 RCV005904086
Primary dilated cardiomyopathy	Conflicting classifications of pathogenicity; Benign; Likely benign	rs750350575, rs143894795, rs141856443, rs777349648	RCV003319230 RCV000853012 RCV000853027 RCV000498433
Restrictive cardiomyopathy	Benign; Likely benign	rs149946443	RCV000853021
Sarcoma	Likely benign; Benign	rs770553269, rs76709221	RCV005916374 RCV005919334
Sudden cardiac death	Conflicting classifications of pathogenicity	rs151021935	RCV000157102
Thyroid cancer, nonmedullary, 1	Benign; Likely benign; Conflicting classifications of pathogenicity	rs142729919, rs140782750	RCV005889672 RCV005899613
unspecified heart condition	Benign; Likely benign	rs150016098	RCV000853459
Uterine corpus endometrial carcinoma	Likely benign; Benign	rs116169457, rs76709221, rs142729919	RCV005914789 RCV005919335 RCV005889673
Ventricular fibrillation	Conflicting classifications of pathogenicity; Benign; Likely benign; Uncertain significance	rs139965373, rs786205707, rs61757673, rs142603711	RCV000157101 RCV000208405 RCV000853023 RCV000208209
Ventricular tachycardia	Uncertain significance; Conflicting classifications of pathogenicity	rs730880042, rs141039834	RCV000157097 RCV000853013
Wolff-Parkinson-White pattern	Uncertain significance; Conflicting classifications of pathogenicity	rs767137372, rs137892407	RCV000656173 RCV000656165

Associations from Text Mining
Disease Name	Relationship Type	References
Alzheimer Disease	Associate	25172201, 29516269, 35307406, 35567427
Anodontia	Associate	26786868
Arrhythmias Cardiac	Associate	27707468
Breast Neoplasms	Associate	21931171, 24943594, 26510858, 27270325, 33407744
Brugada Syndrome	Associate	27707468
Carcinogenesis	Associate	26786868
Cardiomyopathy Dilated	Associate	28750076
Cardiomyopathy Hypertrophic	Associate	28750076
Cardiovascular Diseases	Associate	25087618
Colorectal Neoplasms	Associate	25446987, 26786868, 26887056
Death Sudden Cardiac	Associate	37650513
Dementia	Associate	31836585
Esophageal Squamous Cell Carcinoma	Associate	36966136
Hereditary Breast and Ovarian Cancer Syndrome	Associate	26510858
Idiopathic Pulmonary Fibrosis	Associate	38035073
Inflammatory Bowel Diseases	Associate	32764209
Long QT Syndrome	Associate	20809527, 24561134, 25087618, 28003625, 36395689
Lung Neoplasms	Associate	16741161
Melanoma	Associate	20520718
Neoplasms	Associate	30776432
Prostatic Neoplasms	Associate	31134918
Pulmonary Disease Chronic Obstructive	Associate	24452374
Romano Ward Syndrome	Associate	18093912, 25087618, 37650513
Stomach Diseases	Associate	26786868
Stomach Neoplasms	Associate	31164161
Thyroid cancer follicular	Associate	38203733
Thyroid Diseases	Associate	38203733
Thyroid Neoplasms	Associate	22887574, 38203733