ARPC2 (actin related protein 2/3 complex subunit 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10109 |
| Gene name | Actin related protein 2/3 complex subunit 2 |
| Gene symbol | ARPC2 |
| Synonyms (NCBI Gene) |
ARC34PNAS-139PRO2446p34-Arc
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| Chromosome | 2 |
| Chromosome location | 2q35 |
| Summary | This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by |
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miRNA
miRNA information provided by mirtarbase database.
263
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O15144 | ||||||||||
| Protein name | Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC) | ||||||||||
| Protein function | Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks | ||||||||||
| PDB | 6UHC , 6YW6 , 6YW7 , 8P94 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 300 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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