PPIF (peptidylprolyl isomerase F)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10105 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Peptidylprolyl isomerase F |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PPIF |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CYP3, CyP-M, Cyp-D, CypD |
Chromosome
Chromosome number
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10 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10q22.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P30405 | ||||||||||
Protein name | Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Mitochondrial cyclophilin) (CyP-M) (Rotamase F) | ||||||||||
Protein function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357). Involved in regulation of the mitochondrial permeability transition pore (mPTP) (PubMe | ||||||||||
PDB | 2BIT , 2BIU , 2Z6W , 3QYU , 3R49 , 3R4G , 3R54 , 3R56 , 3R57 , 3R59 , 3RCF , 3RCG , 3RCI , 3RCK , 3RCL , 3RD9 , 3RDA , 3RDB , 3RDC , 4J58 , 4J59 , 4J5A , 4J5B , 4J5C , 4J5D , 4J5E , 4O8H , 4O8I , 4XNC , 4ZSC , 4ZSD , 5A0E , 5CBT , 5CBU , 5CBV , 5CBW , 5CCN , 5CCQ , 5CCR , 5CCS , 6R8L , 6R8O , 6R8W , 6R9S , 6R9U , 6R9X , 6RA1 , 6Y3E , 6YBM , 7OGI , 7PMT | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 207 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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