Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10099
Gene name Gene Name - the full gene name approved by the HGNC.	Tetraspanin 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TSPAN3
Synonyms (NCBI Gene) Gene synonyms aliases	TM4-A, TM4SF8, TSPAN-3
Chromosome Chromosome number	15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	15q24.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate

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miRTarBase ID	miRNA	Experiments	Reference
MIRT000215	hsa-miR-197-3p	Microarray, qRT-PCR	16822819
MIRT020952	hsa-miR-155-5p	Proteomics	18668040
MIRT030069	hsa-miR-26b-5p	Microarray	19088304
MIRT031979	hsa-miR-16-5p	Proteomics	18668040
MIRT052616	hsa-let-7a-5p	CLASH	23622248
MIRT052340	hsa-let-7b-5p	CLASH	23622248
MIRT051380	hsa-let-7f-5p	CLASH	23622248
MIRT031979	hsa-miR-16-5p	CLASH	23622248
MIRT000215	hsa-miR-197-3p	CLASH	23622248
MIRT046454	hsa-miR-15b-5p	CLASH	23622248
MIRT041737	hsa-miR-484	CLASH	23622248
MIRT041737	hsa-miR-484	CLASH	23622248
MIRT553318	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT553317	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT553316	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT553315	hsa-miR-483-3p	PAR-CLIP	21572407
MIRT553314	hsa-miR-323a-3p	PAR-CLIP	21572407
MIRT553313	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT553312	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT553311	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT553310	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT553309	hsa-miR-3666	PAR-CLIP	21572407
MIRT553308	hsa-miR-4295	PAR-CLIP	21572407
MIRT553307	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT553306	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT553305	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT553304	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT553303	hsa-miR-548ac	PAR-CLIP	21572407
MIRT553302	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT553301	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT553300	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT553299	hsa-miR-548z	PAR-CLIP	21572407
MIRT553298	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT553297	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT553296	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT553295	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT553294	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT553293	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT553292	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT553291	hsa-miR-548aa	PAR-CLIP	21572407
MIRT553290	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT553289	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT553288	hsa-miR-497-3p	PAR-CLIP	21572407
MIRT553287	hsa-miR-4528	PAR-CLIP	21572407
MIRT553286	hsa-miR-5689	PAR-CLIP	21572407
MIRT553285	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT553284	hsa-miR-337-3p	PAR-CLIP	21572407
MIRT465088	hsa-miR-562	PAR-CLIP	23592263
MIRT465087	hsa-miR-196a-5p	PAR-CLIP	23592263
MIRT465086	hsa-miR-196b-5p	PAR-CLIP	23592263
MIRT465084	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT465085	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT282122	hsa-miR-5589-3p	PAR-CLIP	23592263
MIRT465083	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT465082	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT465081	hsa-miR-6802-5p	PAR-CLIP	23592263
MIRT000215	hsa-miR-197-3p	qRT-PCR	28418912
MIRT000215	hsa-miR-197-3p	qRT-PCR	28418912
MIRT553318	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT553317	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT553316	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT553315	hsa-miR-483-3p	PAR-CLIP	21572407
MIRT553314	hsa-miR-323a-3p	PAR-CLIP	21572407
MIRT553313	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT553312	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT553311	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT553310	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT553309	hsa-miR-3666	PAR-CLIP	21572407
MIRT553308	hsa-miR-4295	PAR-CLIP	21572407
MIRT553307	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT553306	hsa-miR-199a-3p	PAR-CLIP	21572407
MIRT553305	hsa-miR-199b-3p	PAR-CLIP	21572407
MIRT553304	hsa-miR-3129-5p	PAR-CLIP	21572407
MIRT553303	hsa-miR-548ac	PAR-CLIP	21572407
MIRT553302	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT553301	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT553300	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT553299	hsa-miR-548z	PAR-CLIP	21572407
MIRT553298	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT553297	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT553296	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT553295	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT553294	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT553293	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT553292	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT553291	hsa-miR-548aa	PAR-CLIP	21572407
MIRT553290	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT553289	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT553288	hsa-miR-497-3p	PAR-CLIP	21572407
MIRT553287	hsa-miR-4528	PAR-CLIP	21572407
MIRT553286	hsa-miR-5689	PAR-CLIP	21572407
MIRT553285	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT553284	hsa-miR-337-3p	PAR-CLIP	21572407
MIRT465088	hsa-miR-562	PAR-CLIP	23592263
MIRT465087	hsa-miR-196a-5p	PAR-CLIP	23592263
MIRT465086	hsa-miR-196b-5p	PAR-CLIP	23592263
MIRT465084	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT465085	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT282122	hsa-miR-5589-3p	PAR-CLIP	23592263
MIRT465083	hsa-miR-541-3p	PAR-CLIP	23592263
MIRT465082	hsa-miR-654-5p	PAR-CLIP	23592263
MIRT465081	hsa-miR-6802-5p	PAR-CLIP	23592263
MIRT1459789	hsa-miR-4717-3p	CLIP-seq
MIRT1459790	hsa-miR-605	CLIP-seq
MIRT1459791	hsa-miR-130a	CLIP-seq
MIRT1459792	hsa-miR-130b	CLIP-seq
MIRT1459793	hsa-miR-15a	CLIP-seq
MIRT1459794	hsa-miR-15b	CLIP-seq
MIRT1459795	hsa-miR-16	CLIP-seq
MIRT1459796	hsa-miR-195	CLIP-seq
MIRT1459797	hsa-miR-208a	CLIP-seq
MIRT1459798	hsa-miR-208b	CLIP-seq
MIRT1459799	hsa-miR-301a	CLIP-seq
MIRT1459800	hsa-miR-301b	CLIP-seq
MIRT1459801	hsa-miR-323-3p	CLIP-seq
MIRT1459802	hsa-miR-3611	CLIP-seq
MIRT1459803	hsa-miR-3646	CLIP-seq
MIRT1459804	hsa-miR-424	CLIP-seq
MIRT1459805	hsa-miR-4432	CLIP-seq
MIRT1459806	hsa-miR-4499	CLIP-seq
MIRT1459807	hsa-miR-454	CLIP-seq
MIRT1459808	hsa-miR-4680-5p	CLIP-seq
MIRT1459809	hsa-miR-4720-3p	CLIP-seq
MIRT1459810	hsa-miR-497	CLIP-seq
MIRT1459811	hsa-miR-499-5p	CLIP-seq
MIRT1459812	hsa-miR-508-5p	CLIP-seq
MIRT1459813	hsa-miR-515-5p	CLIP-seq
MIRT1459814	hsa-miR-520a-5p	CLIP-seq
MIRT1459815	hsa-miR-525-5p	CLIP-seq
MIRT1459816	hsa-miR-767-3p	CLIP-seq
MIRT1459817	hsa-miR-922	CLIP-seq
MIRT1459793	hsa-miR-15a	CLIP-seq
MIRT1459794	hsa-miR-15b	CLIP-seq
MIRT1459795	hsa-miR-16	CLIP-seq
MIRT1459796	hsa-miR-195	CLIP-seq
MIRT1459818	hsa-miR-323-5p	CLIP-seq
MIRT1459819	hsa-miR-3606	CLIP-seq
MIRT1459820	hsa-miR-3689d	CLIP-seq
MIRT1459804	hsa-miR-424	CLIP-seq
MIRT1459821	hsa-miR-4536	CLIP-seq
MIRT1459822	hsa-miR-4723-5p	CLIP-seq
MIRT1459823	hsa-miR-4787-5p	CLIP-seq
MIRT1459810	hsa-miR-497	CLIP-seq
MIRT1459814	hsa-miR-520a-5p	CLIP-seq
MIRT1459815	hsa-miR-525-5p	CLIP-seq
MIRT1459824	hsa-miR-876-3p	CLIP-seq
MIRT1459817	hsa-miR-922	CLIP-seq
MIRT1555218	hsa-miR-196a	CLIP-seq
MIRT1555219	hsa-miR-196b	CLIP-seq
MIRT1555220	hsa-miR-3148	CLIP-seq
MIRT1555221	hsa-miR-4709-3p	CLIP-seq
MIRT1555222	hsa-miR-4773	CLIP-seq
MIRT2137977	hsa-miR-3127-3p	CLIP-seq
MIRT2137978	hsa-miR-3926	CLIP-seq
MIRT2137979	hsa-miR-548s	CLIP-seq
MIRT2137980	hsa-miR-1227	CLIP-seq
MIRT2137981	hsa-miR-3910	CLIP-seq
MIRT2137982	hsa-miR-548an	CLIP-seq
MIRT2358904	hsa-miR-197	CLIP-seq
MIRT2358905	hsa-miR-3194-3p	CLIP-seq
MIRT2358906	hsa-miR-4264	CLIP-seq
MIRT1555221	hsa-miR-4709-3p	CLIP-seq
MIRT2358907	hsa-miR-942	CLIP-seq
MIRT2358908	hsa-miR-4529-3p	CLIP-seq
MIRT1459813	hsa-miR-515-5p	CLIP-seq
MIRT2462501	hsa-miR-4722-3p	CLIP-seq
MIRT1555218	hsa-miR-196a	CLIP-seq
MIRT1555219	hsa-miR-196b	CLIP-seq
MIRT1555220	hsa-miR-3148	CLIP-seq
MIRT2652138	hsa-miR-1225-5p	CLIP-seq
MIRT2652139	hsa-miR-1236	CLIP-seq
MIRT1459791	hsa-miR-130a	CLIP-seq
MIRT1459792	hsa-miR-130b	CLIP-seq
MIRT2652140	hsa-miR-1910	CLIP-seq
MIRT1459797	hsa-miR-208a	CLIP-seq
MIRT1459798	hsa-miR-208b	CLIP-seq
MIRT1459799	hsa-miR-301a	CLIP-seq
MIRT1459800	hsa-miR-301b	CLIP-seq
MIRT1459801	hsa-miR-323-3p	CLIP-seq
MIRT2652141	hsa-miR-330-3p	CLIP-seq
MIRT2652142	hsa-miR-340	CLIP-seq
MIRT2652143	hsa-miR-3614-5p	CLIP-seq
MIRT2652144	hsa-miR-3618	CLIP-seq
MIRT2652145	hsa-miR-3661	CLIP-seq
MIRT1459820	hsa-miR-3689d	CLIP-seq
MIRT2652146	hsa-miR-3920	CLIP-seq
MIRT2652147	hsa-miR-3921	CLIP-seq
MIRT2358906	hsa-miR-4264	CLIP-seq
MIRT2652148	hsa-miR-4299	CLIP-seq
MIRT2652149	hsa-miR-4304	CLIP-seq
MIRT2652150	hsa-miR-432	CLIP-seq
MIRT1459805	hsa-miR-4432	CLIP-seq
MIRT2652151	hsa-miR-4437	CLIP-seq
MIRT2652152	hsa-miR-4443	CLIP-seq
MIRT2652153	hsa-miR-4452	CLIP-seq
MIRT1459807	hsa-miR-454	CLIP-seq
MIRT2652154	hsa-miR-455-3p	CLIP-seq
MIRT2652155	hsa-miR-4653-5p	CLIP-seq
MIRT2652156	hsa-miR-4674	CLIP-seq
MIRT2652157	hsa-miR-4699-3p	CLIP-seq
MIRT2652158	hsa-miR-4699-5p	CLIP-seq
MIRT1555221	hsa-miR-4709-3p	CLIP-seq
MIRT2652159	hsa-miR-4711-5p	CLIP-seq
MIRT1459809	hsa-miR-4720-3p	CLIP-seq
MIRT2652160	hsa-miR-4753-3p	CLIP-seq
MIRT2652161	hsa-miR-4760-5p	CLIP-seq
MIRT2652162	hsa-miR-4790-3p	CLIP-seq
MIRT2652163	hsa-miR-4793-5p	CLIP-seq
MIRT2652164	hsa-miR-4797-5p	CLIP-seq
MIRT2652165	hsa-miR-4802-3p	CLIP-seq
MIRT2652166	hsa-miR-488	CLIP-seq
MIRT2652167	hsa-miR-492	CLIP-seq
MIRT1459811	hsa-miR-499-5p	CLIP-seq
MIRT2652168	hsa-miR-548ae	CLIP-seq
MIRT2652169	hsa-miR-548aj	CLIP-seq
MIRT2652170	hsa-miR-548am	CLIP-seq
MIRT2652171	hsa-miR-548x	CLIP-seq
MIRT2652172	hsa-miR-593	CLIP-seq
MIRT2652173	hsa-miR-607	CLIP-seq
MIRT2652174	hsa-miR-622	CLIP-seq
MIRT2652175	hsa-miR-627	CLIP-seq
MIRT2652176	hsa-miR-631	CLIP-seq
MIRT2652177	hsa-miR-890	CLIP-seq
MIRT2652178	hsa-miR-924	CLIP-seq
MIRT2358907	hsa-miR-942	CLIP-seq
MIRT2652138	hsa-miR-1225-5p	CLIP-seq
MIRT2652139	hsa-miR-1236	CLIP-seq
MIRT1459791	hsa-miR-130a	CLIP-seq
MIRT1459792	hsa-miR-130b	CLIP-seq
MIRT2652140	hsa-miR-1910	CLIP-seq
MIRT1459797	hsa-miR-208a	CLIP-seq
MIRT1459798	hsa-miR-208b	CLIP-seq
MIRT1459799	hsa-miR-301a	CLIP-seq
MIRT1459800	hsa-miR-301b	CLIP-seq
MIRT1459801	hsa-miR-323-3p	CLIP-seq
MIRT2652141	hsa-miR-330-3p	CLIP-seq
MIRT2652142	hsa-miR-340	CLIP-seq
MIRT2652143	hsa-miR-3614-5p	CLIP-seq
MIRT2652144	hsa-miR-3618	CLIP-seq
MIRT2652145	hsa-miR-3661	CLIP-seq
MIRT1459820	hsa-miR-3689d	CLIP-seq
MIRT2652146	hsa-miR-3920	CLIP-seq
MIRT2652147	hsa-miR-3921	CLIP-seq
MIRT2358906	hsa-miR-4264	CLIP-seq
MIRT2652148	hsa-miR-4299	CLIP-seq
MIRT2652149	hsa-miR-4304	CLIP-seq
MIRT2652150	hsa-miR-432	CLIP-seq
MIRT1459805	hsa-miR-4432	CLIP-seq
MIRT2652151	hsa-miR-4437	CLIP-seq
MIRT2652152	hsa-miR-4443	CLIP-seq
MIRT2652153	hsa-miR-4452	CLIP-seq
MIRT1459807	hsa-miR-454	CLIP-seq
MIRT2652154	hsa-miR-455-3p	CLIP-seq
MIRT2652155	hsa-miR-4653-5p	CLIP-seq
MIRT2652156	hsa-miR-4674	CLIP-seq
MIRT2652157	hsa-miR-4699-3p	CLIP-seq
MIRT2652158	hsa-miR-4699-5p	CLIP-seq
MIRT1555221	hsa-miR-4709-3p	CLIP-seq
MIRT2652159	hsa-miR-4711-5p	CLIP-seq
MIRT1459809	hsa-miR-4720-3p	CLIP-seq
MIRT2652160	hsa-miR-4753-3p	CLIP-seq
MIRT2652161	hsa-miR-4760-5p	CLIP-seq
MIRT2652162	hsa-miR-4790-3p	CLIP-seq
MIRT2652163	hsa-miR-4793-5p	CLIP-seq
MIRT2652164	hsa-miR-4797-5p	CLIP-seq
MIRT2652165	hsa-miR-4802-3p	CLIP-seq
MIRT2694359	hsa-miR-485-3p	CLIP-seq
MIRT2652166	hsa-miR-488	CLIP-seq
MIRT2652167	hsa-miR-492	CLIP-seq
MIRT1459811	hsa-miR-499-5p	CLIP-seq
MIRT2652168	hsa-miR-548ae	CLIP-seq
MIRT2652169	hsa-miR-548aj	CLIP-seq
MIRT2652170	hsa-miR-548am	CLIP-seq
MIRT2652171	hsa-miR-548x	CLIP-seq
MIRT2652172	hsa-miR-593	CLIP-seq
MIRT2652173	hsa-miR-607	CLIP-seq
MIRT2652174	hsa-miR-622	CLIP-seq
MIRT2652175	hsa-miR-627	CLIP-seq
MIRT2652176	hsa-miR-631	CLIP-seq
MIRT2652177	hsa-miR-890	CLIP-seq
MIRT2652178	hsa-miR-924	CLIP-seq
MIRT2358907	hsa-miR-942	CLIP-seq

Show/Hide all(4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0008150	Process	Biological_process	ND
GO:0070062	Component	Extracellular exosome	HDA	19056867

MIM	HGNC	e!Ensembl
613134	17752	ENSG00000140391

Protein

UniProt ID

O60637

Protein name

Tetraspanin-3 (Tspan-3) (Tetraspanin TM4-A) (Transmembrane 4 superfamily member 8)

Protein function

Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00335	Tetraspanin	9 → 236	Tetraspanin family	Family

Sequence

MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV
GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ
KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS
NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD
PAYELLITGGTYA

Sequence length

253

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237 View all (293 more)	30718926

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Diabetes	Diabetes	GWAS
Uterine Fibroids	Uterine Fibroids	GWAS

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	37047617
Brain Injuries Traumatic	Associate	37047617
Colorectal Neoplasms	Associate	33378017
Glioblastoma	Stimulate	37587203
Neoplasm Metastasis	Associate	33378017
Neoplasms	Associate	35088879

TSPAN3 (tetraspanin 3)