Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	10095
Gene name Gene Name - the full gene name approved by the HGNC.	Actin related protein 2/3 complex subunit 1B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ARPC1B
Synonyms (NCBI Gene) Gene synonyms aliases	ARC41, IMD71, PLTEID, p40-ARC, p41-ARC
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they bo

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SNP ID	Visualize variation	Clinical significance	Consequence
rs111297226	G>A,C	Pathogenic	Splice donor variant
rs760191638	CTGCT>-	Pathogenic	Coding sequence variant, frameshift variant
rs1186149065	C>A,T	Pathogenic	Coding sequence variant, missense variant
rs1584409386	->CC	Pathogenic	Coding sequence variant, frameshift variant
rs1584410808	GA>-	Pathogenic	Coding sequence variant, frameshift variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT002566	hsa-miR-124-3p	Microarray	15685193
MIRT002566	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT002566	hsa-miR-124-3p	Microarray	15685193
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23313552
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23313552
MIRT616873	hsa-miR-3941	HITS-CLIP	23313552
MIRT616872	hsa-miR-4672	HITS-CLIP	23313552
MIRT616871	hsa-miR-466	HITS-CLIP	23313552
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23313552
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT635904	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT635903	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT621204	hsa-miR-1237-5p	HITS-CLIP	23824327
MIRT621203	hsa-miR-4488	HITS-CLIP	23824327
MIRT621202	hsa-miR-4697-5p	HITS-CLIP	23824327
MIRT621201	hsa-miR-6846-5p	HITS-CLIP	23824327
MIRT621200	hsa-miR-6848-5p	HITS-CLIP	23824327
MIRT621199	hsa-miR-1275	HITS-CLIP	23824327
MIRT621198	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT621197	hsa-miR-7109-5p	HITS-CLIP	23824327
MIRT621196	hsa-miR-6751-5p	HITS-CLIP	23824327
MIRT621195	hsa-miR-6803-5p	HITS-CLIP	23824327
MIRT635907	hsa-miR-450a-2-3p	HITS-CLIP	23824327
MIRT635906	hsa-miR-4260	HITS-CLIP	23824327
MIRT635905	hsa-miR-5572	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT635904	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT635903	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT621204	hsa-miR-1237-5p	HITS-CLIP	23824327
MIRT621203	hsa-miR-4488	HITS-CLIP	23824327
MIRT621202	hsa-miR-4697-5p	HITS-CLIP	23824327
MIRT621201	hsa-miR-6846-5p	HITS-CLIP	23824327
MIRT621200	hsa-miR-6848-5p	HITS-CLIP	23824327
MIRT621199	hsa-miR-1275	HITS-CLIP	23824327
MIRT621198	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT621197	hsa-miR-7109-5p	HITS-CLIP	23824327
MIRT621196	hsa-miR-6751-5p	HITS-CLIP	23824327
MIRT621195	hsa-miR-6803-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612122	hsa-miR-4422	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612117	hsa-miR-3653-3p	HITS-CLIP	23824327
MIRT612116	hsa-miR-3658	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT441178	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT441178	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT616870	hsa-miR-2681-5p	PAR-CLIP	26701625
MIRT616870	hsa-miR-2681-5p	PAR-CLIP	26701625
MIRT616870	hsa-miR-2681-5p	PAR-CLIP	26701625
MIRT635904	hsa-miR-33a-5p	PAR-CLIP	26701625
MIRT635904	hsa-miR-33a-5p	PAR-CLIP	26701625
MIRT635904	hsa-miR-33a-5p	PAR-CLIP	26701625
MIRT635903	hsa-miR-33b-5p	PAR-CLIP	26701625
MIRT635903	hsa-miR-33b-5p	PAR-CLIP	26701625
MIRT635903	hsa-miR-33b-5p	PAR-CLIP	26701625
MIRT616873	hsa-miR-3941	PAR-CLIP	26701625
MIRT616873	hsa-miR-3941	PAR-CLIP	26701625
MIRT616873	hsa-miR-3941	PAR-CLIP	26701625
MIRT616871	hsa-miR-466	PAR-CLIP	26701625
MIRT616871	hsa-miR-466	PAR-CLIP	26701625
MIRT616871	hsa-miR-466	PAR-CLIP	26701625
MIRT616872	hsa-miR-4672	PAR-CLIP	26701625
MIRT616872	hsa-miR-4672	PAR-CLIP	26701625
MIRT616872	hsa-miR-4672	PAR-CLIP	26701625
MIRT616875	hsa-miR-6768-5p	PAR-CLIP	26701625
MIRT616875	hsa-miR-6768-5p	PAR-CLIP	26701625
MIRT616875	hsa-miR-6768-5p	PAR-CLIP	26701625
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	27418678
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	27418678
MIRT616873	hsa-miR-3941	HITS-CLIP	27418678
MIRT616873	hsa-miR-3941	HITS-CLIP	27418678
MIRT616871	hsa-miR-466	HITS-CLIP	27418678
MIRT616871	hsa-miR-466	HITS-CLIP	27418678
MIRT616872	hsa-miR-4672	HITS-CLIP	27418678
MIRT616872	hsa-miR-4672	HITS-CLIP	27418678
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	27418678
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	27418678
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	27418678
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23313552
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23313552
MIRT616873	hsa-miR-3941	HITS-CLIP	23313552
MIRT616872	hsa-miR-4672	HITS-CLIP	23313552
MIRT616871	hsa-miR-466	HITS-CLIP	23313552
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23313552
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT635904	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT635903	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT621204	hsa-miR-1237-5p	HITS-CLIP	23824327
MIRT621203	hsa-miR-4488	HITS-CLIP	23824327
MIRT621202	hsa-miR-4697-5p	HITS-CLIP	23824327
MIRT621201	hsa-miR-6846-5p	HITS-CLIP	23824327
MIRT621200	hsa-miR-6848-5p	HITS-CLIP	23824327
MIRT621199	hsa-miR-1275	HITS-CLIP	23824327
MIRT621198	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT621197	hsa-miR-7109-5p	HITS-CLIP	23824327
MIRT621196	hsa-miR-6751-5p	HITS-CLIP	23824327
MIRT621195	hsa-miR-6803-5p	HITS-CLIP	23824327
MIRT635907	hsa-miR-450a-2-3p	HITS-CLIP	23824327
MIRT635906	hsa-miR-4260	HITS-CLIP	23824327
MIRT635905	hsa-miR-5572	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT635904	hsa-miR-33a-5p	HITS-CLIP	23824327
MIRT635903	hsa-miR-33b-5p	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT621204	hsa-miR-1237-5p	HITS-CLIP	23824327
MIRT621203	hsa-miR-4488	HITS-CLIP	23824327
MIRT621202	hsa-miR-4697-5p	HITS-CLIP	23824327
MIRT621201	hsa-miR-6846-5p	HITS-CLIP	23824327
MIRT621200	hsa-miR-6848-5p	HITS-CLIP	23824327
MIRT621199	hsa-miR-1275	HITS-CLIP	23824327
MIRT621198	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT621197	hsa-miR-7109-5p	HITS-CLIP	23824327
MIRT621196	hsa-miR-6751-5p	HITS-CLIP	23824327
MIRT621195	hsa-miR-6803-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT616875	hsa-miR-6768-5p	HITS-CLIP	23824327
MIRT616874	hsa-miR-5003-3p	HITS-CLIP	23824327
MIRT616873	hsa-miR-3941	HITS-CLIP	23824327
MIRT616872	hsa-miR-4672	HITS-CLIP	23824327
MIRT616871	hsa-miR-466	HITS-CLIP	23824327
MIRT616870	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612122	hsa-miR-4422	HITS-CLIP	23824327
MIRT612121	hsa-miR-3646	HITS-CLIP	23824327
MIRT612120	hsa-miR-1252-3p	HITS-CLIP	23824327
MIRT612119	hsa-miR-95-5p	HITS-CLIP	23824327
MIRT612118	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612117	hsa-miR-3653-3p	HITS-CLIP	23824327
MIRT612116	hsa-miR-3658	HITS-CLIP	23824327
MIRT612115	hsa-miR-1305	HITS-CLIP	23824327
MIRT612114	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT799693	hsa-miR-1206	CLIP-seq
MIRT799694	hsa-miR-124	CLIP-seq
MIRT799695	hsa-miR-1263	CLIP-seq
MIRT799696	hsa-miR-127-5p	CLIP-seq
MIRT799697	hsa-miR-181a	CLIP-seq
MIRT799698	hsa-miR-181b	CLIP-seq
MIRT799699	hsa-miR-181c	CLIP-seq
MIRT799700	hsa-miR-181d	CLIP-seq
MIRT799701	hsa-miR-330-3p	CLIP-seq
MIRT799702	hsa-miR-338-3p	CLIP-seq
MIRT799703	hsa-miR-3622a-5p	CLIP-seq
MIRT799704	hsa-miR-4262	CLIP-seq
MIRT799705	hsa-miR-4291	CLIP-seq
MIRT799706	hsa-miR-433	CLIP-seq
MIRT799707	hsa-miR-4473	CLIP-seq
MIRT799708	hsa-miR-4777-3p	CLIP-seq
MIRT799709	hsa-miR-494	CLIP-seq
MIRT799710	hsa-miR-502-5p	CLIP-seq
MIRT799711	hsa-miR-506	CLIP-seq
MIRT799712	hsa-miR-512-3p	CLIP-seq
MIRT799713	hsa-miR-520f	CLIP-seq
MIRT799714	hsa-miR-543	CLIP-seq
MIRT799715	hsa-miR-545	CLIP-seq
MIRT799716	hsa-miR-634	CLIP-seq
MIRT799693	hsa-miR-1206	CLIP-seq
MIRT1936245	hsa-miR-1265	CLIP-seq
MIRT799696	hsa-miR-127-5p	CLIP-seq
MIRT1936246	hsa-miR-1292	CLIP-seq
MIRT799697	hsa-miR-181a	CLIP-seq
MIRT799698	hsa-miR-181b	CLIP-seq
MIRT799699	hsa-miR-181c	CLIP-seq
MIRT799700	hsa-miR-181d	CLIP-seq
MIRT1936247	hsa-miR-2355-5p	CLIP-seq
MIRT1936248	hsa-miR-2392	CLIP-seq
MIRT799701	hsa-miR-330-3p	CLIP-seq
MIRT799702	hsa-miR-338-3p	CLIP-seq
MIRT1936249	hsa-miR-33a	CLIP-seq
MIRT1936250	hsa-miR-33b	CLIP-seq
MIRT799704	hsa-miR-4262	CLIP-seq
MIRT799705	hsa-miR-4291	CLIP-seq
MIRT799706	hsa-miR-433	CLIP-seq
MIRT1936251	hsa-miR-4471	CLIP-seq
MIRT799707	hsa-miR-4473	CLIP-seq
MIRT1936252	hsa-miR-4493	CLIP-seq
MIRT1936253	hsa-miR-4530	CLIP-seq
MIRT799708	hsa-miR-4777-3p	CLIP-seq
MIRT799710	hsa-miR-502-5p	CLIP-seq
MIRT799712	hsa-miR-512-3p	CLIP-seq
MIRT799713	hsa-miR-520f	CLIP-seq
MIRT799714	hsa-miR-543	CLIP-seq
MIRT799715	hsa-miR-545	CLIP-seq
MIRT799716	hsa-miR-634	CLIP-seq
MIRT1936254	hsa-miR-646	CLIP-seq
MIRT799693	hsa-miR-1206	CLIP-seq
MIRT799696	hsa-miR-127-5p	CLIP-seq
MIRT799702	hsa-miR-338-3p	CLIP-seq
MIRT799706	hsa-miR-433	CLIP-seq
MIRT799707	hsa-miR-4473	CLIP-seq
MIRT799712	hsa-miR-512-3p	CLIP-seq
MIRT799713	hsa-miR-520f	CLIP-seq
MIRT799716	hsa-miR-634	CLIP-seq
MIRT1936245	hsa-miR-1265	CLIP-seq
MIRT1936247	hsa-miR-2355-5p	CLIP-seq
MIRT1936248	hsa-miR-2392	CLIP-seq
MIRT1936252	hsa-miR-4493	CLIP-seq
MIRT1936253	hsa-miR-4530	CLIP-seq
MIRT1936254	hsa-miR-646	CLIP-seq
MIRT1936245	hsa-miR-1265	CLIP-seq
MIRT1936247	hsa-miR-2355-5p	CLIP-seq
MIRT1936248	hsa-miR-2392	CLIP-seq
MIRT1936252	hsa-miR-4493	CLIP-seq
MIRT1936253	hsa-miR-4530	CLIP-seq
MIRT2675404	hsa-miR-513a-5p	CLIP-seq
MIRT1936254	hsa-miR-646	CLIP-seq

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IEA
GO:0005200	Function	Structural constituent of cytoskeleton	IDA	11741539
GO:0005200	Function	Structural constituent of cytoskeleton	TAS	9230079
GO:0005515	Function	Protein binding	IPI	25944859
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005885	Component	Arp2/3 protein complex	IBA
GO:0005885	Component	Arp2/3 protein complex	IDA	11741539
GO:0005885	Component	Arp2/3 protein complex	IEA
GO:0005885	Component	Arp2/3 protein complex	TAS	9230079
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0015629	Component	Actin cytoskeleton	TAS	9230079
GO:0032355	Process	Response to estradiol	IEA
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IBA
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IDA	11741539
GO:0034314	Process	Arp2/3 complex-mediated actin nucleation	IEA
GO:0036284	Component	Tubulobulbar complex	IEA
GO:0043627	Process	Response to estrogen	IEA
GO:0044877	Function	Protein-containing complex binding	IEA
GO:0051015	Function	Actin filament binding	IDA	11741539
GO:0070062	Component	Extracellular exosome	HDA	20458337

MIM	HGNC	e!Ensembl
604223	704	ENSG00000130429

Protein

UniProt ID

O15143

Protein name

Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)

Protein function

Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:11741539, PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin netwo

PDB

6UHC , 6YW6 , 8P94

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00400	WD40	42 → 80	WD domain, G-beta repeat	Repeat
PF00400	WD40	132 → 170	WD domain, G-beta repeat	Repeat

Sequence

MAYHSFLVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDW
APESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI
SICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERP
APTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATL
ASETLPLLALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARE
RFQNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVK
SLESALKDLKIK

Sequence length

372

Interactions

View interactions

	KEGG		Reactome
	Endocytosis Tight junction Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton Bacterial invasion of epithelial cells Pathogenic Escherichia coli infection Shigellosis Salmonella infection Yersinia infection		Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis

Show/Hide Causal Diseases (3)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Platelet Abnormalities With Eosinophilia And Immune-Mediated Inflammatory Disease	platelet abnormalities with eosinophilia and immune-mediated inflammatory disease	rs1794454006, rs1186149065, rs1584410808, rs760191638	N/A
Immunodeficiency	Inherited Immunodeficiency Diseases	rs1584409386	N/A
Severe combined immunodeficiency disease	combined immunodeficiency	rs760191638	N/A

Show/Hide Text Mining Associations (37)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Abscess	Associate	31379835
Adenocarcinoma of Lung	Associate	35441736
Asthma	Associate	33679784
Blood Platelet Disorders	Associate	28368018, 35163398
Carcinogenesis	Associate	20345486
CD59 Deficiency	Associate	35163398
Deafness Autosomal Recessive 71	Associate	39277702
Diabetes Mellitus	Associate	40718484
Drug Hypersensitivity	Associate	33679784
Eczema	Associate	31379835
Eosinophilia	Associate	28368018, 35163398
Genetic Diseases Inborn	Associate	33679784, 34135903
Glioblastoma	Associate	35111386, 35185876
Glioma	Associate	35111386
Helicobacter Infections	Stimulate	20345486
Immunologic Deficiency Syndromes	Associate	28368018, 31379835, 34135903
Infections	Associate	30254128, 33679784
Inflammation	Associate	28368018, 33679784, 34135903
Kidney Calculi	Associate	40718484
Kimura Disease	Associate	32846771
Lymphopenia	Associate	30254128
Myopathies Structural Congenital	Associate	35111386
Neoplasm Metastasis	Associate	35163398
Neoplasms	Inhibit	21628992
Neoplasms	Associate	35111386, 35185876
Oligodendroglioma	Associate	29631562
Polyradiculoneuropathy Chronic Inflammatory Demyelinating	Associate	33408168
Positive Pressure Respiration Intrinsic	Associate	32846771
Prostatic Neoplasms	Associate	35163398
Prostatic Neoplasms Castration Resistant	Stimulate	35163398
Severe Combined Immunodeficiency	Associate	33679784
Skin Manifestations	Associate	30254128, 31379835
Syndrome	Associate	33679784
Thrombocytopenia	Associate	30254128, 33679784
Uveal melanoma	Associate	34630418
Wiskott Aldrich Syndrome	Associate	28368018, 29127144
X Linked Combined Immunodeficiency Diseases	Associate	30254128, 33679784

ARPC1B (actin related protein 2/3 complex subunit 1B)