UST (uronyl 2-sulfotransferase)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
10090 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Uronyl 2-sulfotransferase |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
UST |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
2OST, CS-2OST |
Chromosome
Chromosome number
|
6 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
6q25.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008] |
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | |||||||||||
UniProt ID | Q9Y2C2 | ||||||||||
Protein name | Uronyl 2-sulfotransferase (EC 2.8.2.-) (Chondroitin sulfate 2-O-sulfotransferase) (CS-2OST) | ||||||||||
Protein function | Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues in glycosaminoglycan chains (PubMed:10187838, PubMed:17227754). Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity to | ||||||||||
Family and domains |
Pfam
|
||||||||||
Tissue specificity | TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10187838}. | ||||||||||
Sequence |
|
||||||||||
Sequence length | 406 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||||
|
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|