Gene Gene information from NCBI Gene database.
Entrez ID 10090
Gene name Uronyl 2-sulfotransferase
Gene symbol UST
Synonyms (NCBI Gene)
2OSTCS-2OST
Chromosome 6
Chromosome location 6q25.1
Summary Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
487
miRTarBase ID miRNA Experiments Reference
MIRT002811 hsa-miR-1-3p Microarray 15685193
MIRT019065 hsa-miR-335-5p Microarray 18185580
MIRT002811 hsa-miR-1-3p Microarray 15685193
MIRT002811 hsa-miR-1-3p Microarray 18668037
MIRT027844 hsa-miR-98-5p Microarray 19088304
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0000139 Component Golgi membrane TAS
GO:0005794 Component Golgi apparatus IEA
GO:0008146 Function Sulfotransferase activity IBA
GO:0008146 Function Sulfotransferase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610752 17223 ENSG00000111962
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y2C2
Protein name Uronyl 2-sulfotransferase (EC 2.8.2.-) (Chondroitin sulfate 2-O-sulfotransferase) (CS-2OST)
Protein function Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues in glycosaminoglycan chains (PubMed:10187838, PubMed:17227754). Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity to
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03567 Sulfotransfer_2 97 358 Sulfotransferase family Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:10187838}.
Sequence
Sequence length 406
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate   Dermatan sulfate biosynthesis