MYZAP (myocardial zonula adherens protein)

Gene
Gene miRNA Gene ontology Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
100820829
Gene name Gene Name - the full gene name approved by the HGNC.
Myocardial zonula adherens protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MYZAP
Synonyms (NCBI Gene) Gene synonyms aliases
CMD2K, GCOM1, Gup, MYOZAP
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q21.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a protein that is abundantly expressed in cardiac tissue. The encoded protein localizes to intercalated discs in cardiomyocytes and functions as an activator of Rho-dependent serum-response factor signaling. Alternative splicing results
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Associated diseases
Show/Hide all(44)
miRTarBase ID miRNA Experiments Reference
MIRT550546 hsa-miR-4282 PAR-CLIP 21572407
MIRT550545 hsa-miR-1277-5p PAR-CLIP 21572407
MIRT550544 hsa-miR-590-3p PAR-CLIP 21572407
MIRT550543 hsa-miR-338-5p PAR-CLIP 21572407
MIRT550542 hsa-miR-4731-3p PAR-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Associated diseases
Show/Hide all(17)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20412299
GO:0005665 Component RNA polymerase II, core complex IBA
GO:0005737 Component Cytoplasm IEA
GO:0005856 Component Cytoskeleton IEA
GO:0005886 Component Plasma membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Associated diseases
MIM HGNC e!Ensembl
614071 43444 ENSG00000263155
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Associated diseases
Show/Hide Causal Diseases (1)
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Disease merge term Disease name dbSNP ID References
Cardiomyopathy Primary dilated cardiomyopathy rs992189342 N/A
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Atrial Fibrillation Atrial fibrillation N/A N/A GWAS