PCAT1 (prostate cancer associated transcript 1)

Gene
Gene miRNA Other IDs Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
100750225
Gene name Gene Name - the full gene name approved by the HGNC.
Prostate cancer associated transcript 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PCAT1
Synonyms (NCBI Gene) Gene synonyms aliases
PCA1, PCAT-1, PiHL
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8q24.21
Summary Summary of gene provided in NCBI Entrez Gene.
This gene produces a long non-coding RNA that promotes cell proliferation and is upregulated in prostate, colorectal, and other cancers. This RNA negatively regulates the BRCA2 tumor suppressor protein and positively regulates Myc oncoprotein. It contains
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Other IDs Associated diseases
Show/Hide all(2)
miRTarBase ID miRNA Experiments Reference
MIRT735699 hsa-miR-129-5p Luciferase reporter assay, Immunoprecipitaion (IP), Immunohistochemistry (IHC), qRT-PCR 32048803
MIRT737419 hsa-miR-508-3p Luciferase reporter assay, Western blotting, qRT-PCR 31920393
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Other IDs Associated diseases
MIM HGNC e!Ensembl
616043 43022 ENSG00000253438
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Other IDs Associated diseases
Show/Hide Unknown Diseases (12)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Breast cancer Breast cancer (early onset), Breast cancer N/A N/A GWAS
Breast Cancer Postmenopausal breast cancer, Breast cancer (estrogen-receptor negative) N/A N/A GWAS
Colorectal Cancer Early onset colorectal cancer, Colorectal cancer, Colorectal cancer (PheCode 153), ICD10 C18, C19, C20: colorectal cancer N/A N/A GWAS
Diabetes Type 2 diabetes or prostate cancer (pleiotropy) N/A N/A GWAS
Show/Hide Text Mining Associations (42)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 31464517
Anemia Hemolytic Associate 24693973
Bone Diseases Associate 34564896
Cap Myopathy Associate 32059012
Carcinogenesis Associate 35415876
Carcinoma Hepatocellular Associate 26097602, 33829443
Carcinoma Non Small Cell Lung Associate 31464517, 32114419, 35415876
Carcinoma Squamous Cell Associate 31464517
Colonic Neoplasms Associate 31694571
Colorectal Neoplasms Associate 24204606, 30205577, 31253700, 31694571, 33094859, 33277833