Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	10063
Gene name	Cytochrome c oxidase copper chaperone COX17
Gene symbol	COX17
Synonyms (NCBI Gene)	-
Chromosome	3
Chromosome location	3q13.33
Summary	Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochond

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miRTarBase ID	miRNA	Experiments	Reference
MIRT045209	hsa-miR-186-5p	CLASH	23622248
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT635877	hsa-miR-1284	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT635877	hsa-miR-1284	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT635877	hsa-miR-1284	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT635877	hsa-miR-1284	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT635877	hsa-miR-1284	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT635877	hsa-miR-1284	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT612014	hsa-miR-6782-3p	HITS-CLIP	23824327
MIRT612013	hsa-miR-875-5p	HITS-CLIP	23824327
MIRT612012	hsa-miR-1207-3p	HITS-CLIP	23824327
MIRT612011	hsa-miR-4251	HITS-CLIP	23824327
MIRT612010	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT612009	hsa-miR-3144-3p	HITS-CLIP	23824327
MIRT612008	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT612007	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT612006	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT612005	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT905066	hsa-miR-338-5p	CLIP-seq
MIRT905067	hsa-miR-340	CLIP-seq
MIRT905068	hsa-miR-3692	CLIP-seq
MIRT905069	hsa-miR-3973	CLIP-seq
MIRT905070	hsa-miR-4659a-3p	CLIP-seq
MIRT905071	hsa-miR-4659b-3p	CLIP-seq
MIRT905072	hsa-miR-4778-3p	CLIP-seq
MIRT905073	hsa-miR-520g	CLIP-seq
MIRT905074	hsa-miR-520h	CLIP-seq
MIRT905075	hsa-miR-600	CLIP-seq
MIRT1968430	hsa-miR-1298	CLIP-seq
MIRT1968431	hsa-miR-377	CLIP-seq
MIRT1968432	hsa-miR-873	CLIP-seq
MIRT1968433	hsa-miR-944	CLIP-seq
MIRT1968430	hsa-miR-1298	CLIP-seq
MIRT2204261	hsa-miR-150	CLIP-seq
MIRT2204262	hsa-miR-3133	CLIP-seq
MIRT905069	hsa-miR-3973	CLIP-seq
MIRT2204263	hsa-miR-4511	CLIP-seq
MIRT905072	hsa-miR-4778-3p	CLIP-seq
MIRT905073	hsa-miR-520g	CLIP-seq
MIRT905074	hsa-miR-520h	CLIP-seq
MIRT1968432	hsa-miR-873	CLIP-seq
MIRT1968433	hsa-miR-944	CLIP-seq

Show/Hide all (28)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005507	Function	Copper ion binding	IEA
GO:0005507	Function	Copper ion binding	TAS	9050918
GO:0005515	Function	Protein binding	IPI	16189514, 18458339, 19182799, 25416956, 29568061, 32296183, 32814053
GO:0005737	Component	Cytoplasm	IDA	19393246
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	9050918
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005758	Component	Mitochondrial intermembrane space	IBA
GO:0005758	Component	Mitochondrial intermembrane space	IDA	19393246
GO:0005758	Component	Mitochondrial intermembrane space	IEA
GO:0005758	Component	Mitochondrial intermembrane space	TAS
GO:0006091	Process	Generation of precursor metabolites and energy	TAS	9050918
GO:0006825	Process	Copper ion transport	TAS	9050918
GO:0007507	Process	Heart development	IEA
GO:0008047	Function	Enzyme activator activity	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	19393246
GO:0016531	Function	Copper chaperone activity	IBA
GO:0016531	Function	Copper chaperone activity	IEA
GO:0016531	Function	Copper chaperone activity	IMP	19393246
GO:0016531	Function	Copper chaperone activity	ISS
GO:0033617	Process	Mitochondrial cytochrome c oxidase assembly	IBA
GO:0033617	Process	Mitochondrial cytochrome c oxidase assembly	IEA
GO:0033617	Process	Mitochondrial cytochrome c oxidase assembly	IMP	19393246
GO:0046872	Function	Metal ion binding	IEA
GO:1903136	Function	Cuprous ion binding	IDA	18093982
GO:1904960	Process	Positive regulation of cytochrome-c oxidase activity	IMP	19393246

MIM	HGNC	e!Ensembl
604813	2264	ENSG00000138495

Q14061

Protein name

Cytochrome c oxidase copper chaperone

Protein function

Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions

PDB

2L0Y , 2LGQ , 2RN9 , 2RNB

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05051	COX17	18 → 63	Cytochrome C oxidase copper chaperone (COX17)	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10982038}.

Sequence

MPGLVDSNPAPPESQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALG
FKI

Sequence length

Interactions

View interactions

	KEGG
	Oxidative phosphorylation Metabolic pathways Thermogenesis

COX17 (cytochrome c oxidase copper chaperone COX17)