Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10063
Gene name Gene Name - the full gene name approved by the HGNC.
Cytochrome c oxidase copper chaperone COX17
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
COX17
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q13.33
Summary Summary of gene provided in NCBI Entrez Gene.
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochond
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT045209 hsa-miR-186-5p CLASH 23622248
MIRT612014 hsa-miR-6782-3p HITS-CLIP 23824327
MIRT612013 hsa-miR-875-5p HITS-CLIP 23824327
MIRT612012 hsa-miR-1207-3p HITS-CLIP 23824327
MIRT612011 hsa-miR-4251 HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005507 Function Copper ion binding TAS 9050918
GO:0005515 Function Protein binding IPI 16189514, 18458339, 19182799, 25416956, 29568061, 32296183, 32814053
GO:0005737 Component Cytoplasm IDA 19393246
GO:0005758 Component Mitochondrial intermembrane space IBA 21873635
GO:0005758 Component Mitochondrial intermembrane space IDA 19393246
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604813 2264 ENSG00000138495
Protein
UniProt ID Q14061
Protein name Cytochrome c oxidase copper chaperone
Protein function Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions
PDB 2L0Y , 2LGQ , 2RN9 , 2RNB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05051 COX17 18 63 Cytochrome C oxidase copper chaperone (COX17) Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:10982038}.
Sequence
Sequence length 63
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Oxidative phosphorylation
Metabolic pathways
Thermogenesis
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 23624903
Associations from Text Mining
Disease Name Relationship Type References
Cardiomyopathy Dilated Inhibit 27711126
Colorectal Neoplasms Associate 38078879