Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	100528032
Gene name Gene Name - the full gene name approved by the HGNC.	KLRC4-KLRK1 readthrough
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KLRC4-KLRK1
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12p13.2
Summary Summary of gene provided in NCBI Entrez Gene.	This locus represents naturally occurring read-through transcription between the neighboring KLRC4 (killer cell lectin-like receptor subfamily C, member 4) and KLRK1 (killer cell lectin-like receptor subfamily K, member 1) genes on chromosome 12. The read

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miRTarBase ID	miRNA	Experiments
MIRT1099217	hsa-miR-103b	CLIP-seq
MIRT1099218	hsa-miR-1236	CLIP-seq
MIRT1099219	hsa-miR-205	CLIP-seq
MIRT1099220	hsa-miR-331-3p	CLIP-seq
MIRT1099221	hsa-miR-4292	CLIP-seq
MIRT1099222	hsa-miR-4420	CLIP-seq
MIRT1099223	hsa-miR-4496	CLIP-seq
MIRT1099224	hsa-miR-4753-3p	CLIP-seq
MIRT1099225	hsa-miR-548p	CLIP-seq
MIRT1099226	hsa-miR-942	CLIP-seq
MIRT2026944	hsa-miR-124	CLIP-seq
MIRT2026945	hsa-miR-4641	CLIP-seq
MIRT2026946	hsa-miR-4711-3p	CLIP-seq
MIRT2026947	hsa-miR-506	CLIP-seq
MIRT2026948	hsa-miR-593	CLIP-seq
MIRT2026949	hsa-miR-649	CLIP-seq
MIRT2452706	hsa-miR-1291	CLIP-seq
MIRT2452707	hsa-miR-3173-5p	CLIP-seq
MIRT2452708	hsa-miR-328	CLIP-seq
MIRT2026945	hsa-miR-4641	CLIP-seq
MIRT2452709	hsa-miR-663b	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0002223	Process	Stimulatory C-type lectin receptor signaling pathway	IEA
GO:0002250	Process	Adaptive immune response	IEA
GO:0002376	Process	Immune system process	IEA
GO:0005515	Function	Protein binding	IPI	10426993, 10426994, 11323699, 11754823, 15240696, 18544572, 19424970, 19436053, 19658097, 21712812, 23696226, 28559451, 32296183
GO:0005886	Component	Plasma membrane	IDA	17562706
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	2007850
GO:0006809	Process	Nitric oxide biosynthetic process	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	2007850
GO:0009897	Component	External side of plasma membrane	IBA
GO:0009897	Component	External side of plasma membrane	IEA
GO:0009986	Component	Cell surface	IDA	10426994, 15294961
GO:0009986	Component	Cell surface	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	9683661
GO:0030101	Process	Natural killer cell activation	IEA
GO:0030101	Process	Natural killer cell activation	IEA
GO:0030101	Process	Natural killer cell activation	TAS	18676862
GO:0030154	Process	Cell differentiation	IEA
GO:0030246	Function	Carbohydrate binding	IEA
GO:0031295	Process	T cell costimulation	TAS	18676862
GO:0032394	Function	MHC class Ib receptor activity	IEA
GO:0032729	Process	Positive regulation of type II interferon production	IEA
GO:0034260	Process	Negative regulation of GTPase activity	IDA	22585739
GO:0038023	Function	Signaling receptor activity	IBA
GO:0038023	Function	Signaling receptor activity	IDA	17562706
GO:0038023	Function	Signaling receptor activity	IEA
GO:0038023	Function	Signaling receptor activity	TAS	2007850
GO:0042267	Process	Natural killer cell mediated cytotoxicity	IDA	16582911
GO:0042267	Process	Natural killer cell mediated cytotoxicity	IDA	17562706
GO:0042288	Function	MHC class I protein binding	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0045429	Process	Positive regulation of nitric oxide biosynthetic process	IEA
GO:0045954	Process	Positive regulation of natural killer cell mediated cytotoxicity	IBA
GO:0045954	Process	Positive regulation of natural killer cell mediated cytotoxicity	IDA	15294961
GO:0045954	Process	Positive regulation of natural killer cell mediated cytotoxicity	IEA
GO:0050830	Process	Defense response to Gram-positive bacterium	IEA
GO:0051240	Process	Positive regulation of multicellular organismal process	IEA
GO:0071222	Process	Cellular response to lipopolysaccharide	IEA
GO:0098542	Process	Defense response to other organism	IEA
GO:2000502	Process	Negative regulation of natural killer cell chemotaxis	IDA	22585739

MIM	HGNC	e!Ensembl
HGNC	48357	N/A

	KEGG		Reactome
	Natural killer cell mediated cytotoxicity Malaria		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 signaling

KLRC4-KLRK1 (KLRC4-KLRK1 readthrough)