Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Behcet syndrome |
Behcet Syndrome |
rs886040969, rs886039866, rs746055479, rs752615209, rs774164456, rs751454741 |
23041938 |
Diabetes mellitus |
Diabetes Mellitus, Insulin-Dependent |
rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs80356663, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs371977235, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261 View all (293 more) |
17632545 |
Rheumatoid arthritis |
Rheumatoid Arthritis |
rs587776843 |
21653640, 19503088, 21156761 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Cervical Cancer |
Cervical Cancer |
Our screens identified 10 miRNAs that enhance fitness of HeLa cells and have been reported to be up-regulated in cervical cancer (Table2). |
|
GWAS, CBGDA |
Ankylosing Spondylitis |
Ankylosing Spondylitis |
|
|
GWAS |
Asthma |
Asthma |
|
|
GWAS |
Allergic Sensitization |
Allergic Sensitization |
|
|
GWAS |
Carcinoma |
Carcinoma |
|
|
GWAS |
Giant Cell Arteritis |
Giant Cell Arteritis |
|
|
GWAS |
Psoriasis |
Psoriasis |
|
|
GWAS |
Gout |
Gout |
|
|
GWAS |
Takayasu Arteritis |
Takayasu Arteritis |
|
|
GWAS |
Systemic lupus erythematosus |
Systemic lupus erythematosus |
|
|
GWAS |
Iritis |
Iritis |
|
|
GWAS |
Uveitis |
Uveitis |
|
|
GWAS |
Colorectal Cancer |
Colorectal Cancer |
In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. |
|
GWAS, CBGDA |
Hypothyroidism |
Hypothyroidism |
|
|
GWAS |
Insomnia |
Insomnia |
|
|
GWAS |
Myocardial Infarction |
Myocardial Infarction |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Addison Disease |
Associate
|
19820007, 24614117 |
Agranulocytosis |
Associate
|
26070312, 27157822 |
Alopecia Areata |
Associate
|
16417220 |
AMR Syndrome |
Associate
|
21199204 |
Arthritis Juvenile |
Associate
|
37741520 |
Arthritis Psoriatic |
Associate
|
30177859 |
Arthritis Rheumatoid |
Associate
|
11407684, 12878725, 14730600, 19409079, 32123296, 32831971 |
Asthma |
Associate
|
27439200 |
Atherosclerosis |
Associate
|
22170063 |
Autoimmune Diseases |
Associate
|
15055739, 16178876, 16417220, 19662431, 21506888, 36958849 |
Barrett Esophagus |
Associate
|
35437997 |
Behcet Syndrome |
Associate
|
10205273, 10513813, 11796403, 12068141, 15529349, 15934084, 16784494, 21506888, 24136464, 24821759, 25889189, 26331842, 30252881, 31350414, 39317938, 9037047 View all (1 more) |
Bone Marrow Diseases |
Associate
|
15328155 |
Breast Neoplasms |
Associate
|
1718386, 21069948, 22301547, 27026046, 34077462, 36641654 |
Bronchiolitis Obliterans Syndrome |
Associate
|
19786616, 27549307 |
Calcinosis Cutis |
Inhibit
|
10079252, 23975858 |
Carcinogenesis |
Associate
|
11918717, 23024757, 26125933 |
Carcinoma |
Associate
|
15205239 |
Carcinoma |
Stimulate
|
18208618 |
Carcinoma Basal Cell |
Associate
|
22006220 |
Carcinoma Hepatocellular |
Associate
|
18754878, 22302133, 22704489, 23024757, 23593449, 24204805, 24357186, 25031731, 25228093, 25393367, 26517016, 26893439, 27998720, 28427234, 28928439, 30361527, 30723271, 30912093, 31471884, 32683508, 36210637 View all (6 more) |
Carcinoma Non Small Cell Lung |
Associate
|
16187081, 23935919, 23975858, 25363527 |
Carcinoma Ovarian Epithelial |
Associate
|
22258792 |
Carcinoma Pancreatic Ductal |
Associate
|
33820913 |
Carcinoma Renal Cell |
Associate
|
19568411, 24289557, 24641397, 35936986 |
Carcinoma Renal Cell |
Stimulate
|
26349747 |
Carcinoma Squamous Cell |
Associate
|
11918717 |
CD59 Deficiency |
Associate
|
33437901 |
Celiac Disease |
Associate
|
15357948 |
Chagas Disease |
Associate
|
34489964 |
Chemical and Drug Induced Liver Injury |
Associate
|
21948571 |
Cholangiocarcinoma |
Associate
|
26373575, 35223192 |
Cholangitis Sclerosing |
Associate
|
25521205 |
Colitis Ulcerative |
Associate
|
11737059, 16178876, 19662431, 26940143 |
Colorectal Neoplasms |
Associate
|
30988067, 34719204, 36958849 |
Communicable Diseases |
Associate
|
22370708 |
COVID 19 |
Associate
|
35805975 |
Crohn Disease |
Associate
|
28684217 |
Cytomegalovirus Infections |
Associate
|
31881183 |
Dermatomyositis |
Associate
|
39447013 |
Diabetes Mellitus |
Associate
|
21506888, 7913951 |
Diabetes Mellitus Type 1 |
Associate
|
22323559, 7913951 |
Diarrhea Chronic with Villous Atrophy |
Associate
|
15357948 |
Disease |
Associate
|
11839711 |
Drug Hypersensitivity Syndrome |
Associate
|
26190474 |
Enterocolitis Neutropenic |
Associate
|
20460636 |
Eosinophilic Esophagitis |
Associate
|
35437997 |
Fibrocystic Breast Disease |
Inhibit
|
29090365 |
Fibrosis |
Associate
|
28427234, 30723271, 31471884, 33437901 |
GATA2 Deficiency |
Associate
|
20667578, 23935919 |
Glaucoma |
Associate
|
25549595 |
Glycosuria Renal |
Associate
|
21199204, 22631059 |
Gout |
Associate
|
35451026 |
Graft vs Host Disease |
Associate
|
19654407, 25064744, 26483398, 27549307, 27987385, 28088489, 32153595 |
Hemolytic Uremic Syndrome |
Stimulate
|
19155520 |
Hepatitis B |
Associate
|
23024757 |
Hepatitis C |
Associate
|
31471884 |
Hepatitis C Chronic |
Associate
|
28427234, 28928439, 30723271, 30912093, 31471884 |
Hepatitis C Chronic |
Inhibit
|
32683508 |
HIV Infections |
Associate
|
20667578 |
Hyperlipoproteinemia Type II |
Associate
|
21199204 |
Hypoxia |
Inhibit
|
29693186 |
Hypoxia |
Associate
|
31402756 |
Idiopathic Noncirrhotic Portal Hypertension |
Associate
|
27998720 |
Idiopathic Pulmonary Fibrosis |
Inhibit
|
29090365 |
Immune System Diseases |
Associate
|
19155520 |
Immuno hemolytic anemia |
Associate
|
28379387 |
Infections |
Associate
|
15051759, 34650566 |
Infections |
Stimulate
|
21857986, 27733551 |
Infectious Mononucleosis |
Associate
|
2828228 |
Inflammation |
Associate
|
21948571, 26646698, 30794652, 36754452 |
Inflammatory Bowel Disease 2 |
Associate
|
11737059 |
Inflammatory Bowel Diseases |
Associate
|
11737059, 19230040 |
Intraocular Lymphoma |
Associate
|
25549595 |
Kidney Diseases |
Associate
|
22631059 |
Kidney Failure Chronic |
Stimulate
|
19155520 |
Kidney Neoplasms |
Associate
|
24641397, 25987057 |
Laryngeal Neoplasms |
Associate
|
18312485 |
Latent Autoimmune Diabetes in Adults |
Associate
|
22323559 |
Leukemia |
Associate
|
16585609, 21477352, 22215138, 23445485, 30063799 |
Leukemia Large Granular Lymphocytic |
Associate
|
20460636 |
Leukemia Lymphocytic Chronic B Cell |
Associate
|
22215138 |
Leukemia Myelogenous Chronic BCR ABL Positive |
Associate
|
16046526, 16585609 |
Leukemia Myeloid |
Associate
|
22304689 |
Leukemia Myeloid Acute |
Associate
|
29449224, 37143070 |
Liver Cirrhosis |
Associate
|
22370708, 28427234, 30723271 |
Liver Diseases |
Associate
|
18754878, 28427234 |
Lung Neoplasms |
Associate
|
23935919 |
Lung Neoplasms |
Inhibit
|
23975858 |
Lung Neoplasms |
Stimulate
|
37679517 |
Lupus Erythematosus Systemic |
Associate
|
21702010, 34012432 |
Lymphatic Metastasis |
Inhibit
|
15962390 |
Lymphatic Metastasis |
Associate
|
25031731 |
Lymphatic Metastasis |
Stimulate
|
26349747 |
Melanoma |
Associate
|
10079252, 10478640, 17934731, 24994597, 26564811, 7543821, 9637706 |
Monoclonal Gammopathy of Undetermined Significance |
Associate
|
18202175 |
Mouth Neoplasms |
Associate
|
33730629 |
Multiple Myeloma |
Associate
|
18202175, 23686482, 26269456, 27903272, 29765374, 34482362, 35967396, 37460534, 38191242 |
Multiple Sclerosis |
Associate
|
22184268 |
Myelodysplastic Syndromes |
Associate
|
17341666 |
Nasopharyngeal Carcinoma |
Associate
|
18087217, 21536588 |
Neoplasm Metastasis |
Stimulate
|
15205239 |
Neoplasms |
Associate
|
10359807, 12712472, 14983503, 15051759, 15962390, 16585609, 16636811, 16754847, 17109473, 17635809, 18422748, 19048252, 19109132, 19124832, 19289577, 19615970, 20848094, 20871627, 21061445, 21211023, 21352198, 21477352, 21935360, 22215138, 22524849, 22704489, 23226940, 23937717, 24359553, 26125933, 26349747, 26373575, 26708143, 28334733, 28379387, 28771222, 29487978, 29496042, 30063799, 30361527, 30742113, 31435903, 32683508, 32849657, 32968163, 33730629, 33868281, 34719204, 35223192, 35936986, 36641654, 36958849, 37298418, 38035108 View all (39 more) |
Neoplasms |
Inhibit
|
15205239, 25031731, 2829169 |
Neoplasms |
Stimulate
|
29279329 |
Neoplasms Glandular and Epithelial |
Associate
|
32214110 |
Neoplasms Squamous Cell |
Associate
|
16061555 |
Neuroblastoma |
Associate
|
15548365, 21061445, 36521927 |
Nevus |
Inhibit
|
10079252 |
Optic Nerve Neoplasms |
Inhibit
|
14983503 |
Ovarian Neoplasms |
Associate
|
21935360 |
Pancreatic Neoplasms |
Associate
|
31166958 |
Parasitic Diseases |
Associate
|
22370708 |
Peripheral Nervous System Diseases |
Associate
|
11737059 |
Pleural Effusion |
Associate
|
15328155 |
Precursor Cell Lymphoblastic Leukemia Lymphoma |
Associate
|
16010586 |
Prostatic Neoplasms Castration Resistant |
Associate
|
29693186 |
Prosthesis Failure |
Associate
|
23935919 |
Psoriasis |
Associate
|
21506888, 25087609 |
Renal Insufficiency Chronic |
Associate
|
28419176 |
Retinoblastoma |
Associate
|
14983503 |
Schistosomiasis |
Associate
|
22370708 |
Sezary Syndrome |
Associate
|
18754036 |
Sjogren's Syndrome |
Associate
|
28379387 |
Small Cell Lung Carcinoma |
Associate
|
1325431 |
Spondylitis Ankylosing |
Associate
|
23727634, 30177859 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
19414815, 22524849, 33730629 |
Stomach Neoplasms |
Associate
|
15150599, 26708143, 33868281 |
Stomach Neoplasms |
Inhibit
|
15962390 |
Takayasu Arteritis |
Associate
|
26996483 |
Tertiary Lymphoid Structures |
Inhibit
|
23975858 |
Thyroiditis Autoimmune |
Associate
|
22006220 |
Triple Negative Breast Neoplasms |
Associate
|
37685962 |
Uterine Cervical Dysplasia |
Associate
|
16061555 |
Uterine Cervical Neoplasms |
Associate
|
10727458, 18208618, 21477352, 24403192, 33794208 |
Uveal melanoma |
Associate
|
15205239 |
Uveal melanoma |
Inhibit
|
15381927 |
Vascular System Injuries |
Associate
|
22170063 |
Ventricular Dysfunction Left |
Associate
|
34489964 |
Virus Diseases |
Stimulate
|
23024757, 26982091 |
Virus Diseases |
Associate
|
23226940 |
Vitiligo |
Associate
|
31877315 |
|