Gene Gene information from NCBI Gene database.
Entrez ID 100507290
Gene name Zinc finger protein 865
Gene symbol ZNF865
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19q13.42
miRNA miRNA information provided by mirtarbase database.
504
miRTarBase ID miRNA Experiments Reference
MIRT514453 hsa-miR-4438 HITS-CLIP 23313552
MIRT539605 hsa-miR-6504-3p HITS-CLIP 23313552
MIRT689518 hsa-miR-4269 HITS-CLIP 23313552
MIRT689517 hsa-miR-6715b-5p HITS-CLIP 23313552
MIRT689516 hsa-miR-4740-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0003677 Function DNA binding IEA
GO:0003700 Function DNA-binding transcription factor activity IBA
GO:0005634 Component Nucleus IEA
GO:0006357 Process Regulation of transcription by RNA polymerase II IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P0CJ78
Protein name Zinc finger protein 865
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 224 246 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 252 277 Domain
PF00096 zf-C2H2 350 372 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 378 400 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 407 429 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 440 466 Domain
PF00096 zf-C2H2 550 572 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 606 628 Zinc finger, C2H2 type Domain
PF13912 zf-C2H2_6 697 721 Domain
PF00096 zf-C2H2 904 926 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 932 954 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 960 982 Zinc finger, C2H2 type Domain
Sequence
MEANPAGSGAGGGGSSGIGGEDGVHFQSYPFDFLEFLNHQRFEPMELYGEHAKAVAALPC
APGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAK
KPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAP
AGAPGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKSFKQSSHLV
QHMLVH
SGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGPHLPPLGLPAPA
ASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFACPLCWKVFK
KPSHLHQHQIIH
TGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPCGICGKAFRDAS
YLLKHQAAH
AGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKDGAASA
PQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGG
SGASVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVH
TRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTS
AGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVHQ
A
APERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAG
AGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRR
SHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTG
ERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAY
RCEHCGKGFFYLSSVLRHQRAH
EPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCS
SCGEGFANTYGLKKHRLAHKAENLGGPGAGAGTLAGKDA
Sequence length 1059
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
INSOMNIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ZNF865-related disorder Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Esophageal Neoplasms Associate 37013470
★☆☆☆☆
Found in Text Mining only